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01.04.2011 | Original paper

Postdiagnosis diet quality, the combination of diet quality and recreational physical activity, and prognosis after early-stage breast cancer

verfasst von: Stephanie M. George, Melinda L. Irwin, Ashley W. Smith, Marian L. Neuhouser, Jill Reedy, Anne McTiernan, Catherine M. Alfano, Leslie Bernstein, Cornelia M. Ulrich, Kathy B. Baumgartner, Steven C. Moore, Demetrius Albanes, Susan T. Mayne, Mitchell H. Gail, Rachel Ballard-Barbash

Erschienen in: Cancer Causes & Control | Ausgabe 4/2011

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Abstract

Objective

To investigate, among women with breast cancer, how postdiagnosis diet quality and the combination of diet quality and recreational physical activity are associated with prognosis.

Methods

This multiethnic, prospective observational cohort included 670 women diagnosed with local or regional breast cancer. Thirty months after diagnosis, women completed self-report assessments on diet and physical activity and were followed for 6 years. Cox proportional hazards models were used to estimate hazard ratios (HR) and 95% confidence intervals for death from any cause and breast cancer death.

Results

Women consuming better-quality diets, as defined by higher Healthy Eating Index-2005 scores, had a 60% reduced risk of death from any cause (HR_Q4:Q1: 0.40, 95% CI: 0.17, 0.94) and an 88% reduced risk of death from breast cancer (HR_Q4:Q1: 0.12, 95% CI: 0.02, 0.99). Compared with inactive survivors consuming poor-quality diets, survivors engaging in any recreational physical activity and consuming better-quality diets had an 89% reduced risk of death from any cause (HR: 0.11, 95% CI: 0.04, 0.36) and a 91% reduced risk of death from breast cancer (HR: 0.09, 95% CI: 0.01, 0.89). Associations observed were independent of obesity status.

Conclusion

Women diagnosed with localized or regional breast cancer may improve prognosis by adopting better-quality dietary patterns and regular recreational physical activity. Lifestyle interventions emphasizing postdiagnosis behavior changes are advisable in breast cancer survivors.

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Titel: Postdiagnosis diet quality, the combination of diet quality and recreational physical activity, and prognosis after early-stage breast cancer
verfasst von: Stephanie M. George
Melinda L. Irwin
Ashley W. Smith
Marian L. Neuhouser
Jill Reedy
Anne McTiernan
Catherine M. Alfano
Leslie Bernstein
Cornelia M. Ulrich
Kathy B. Baumgartner
Steven C. Moore
Demetrius Albanes
Susan T. Mayne
Mitchell H. Gail
Rachel Ballard-Barbash
Publikationsdatum: 01.04.2011
Verlag: Springer Netherlands
Erschienen in: Cancer Causes & Control / Ausgabe 4/2011
Print ISSN: 0957-5243
Elektronische ISSN: 1573-7225
DOI: https://doi.org/10.1007/s10552-011-9732-9

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Postdiagnosis diet quality, the combination of diet quality and recreational physical activity, and prognosis after early-stage breast cancer