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Journal of Natural Medicines
Erschienen in: Journal of Natural Medicines 1/2022

22.09.2021 | Original Paper

Cliniatines A–C, new Amaryllidaceae alkaloids from Clivia miniata, inhibiting Acetylcholinesterase

verfasst von: Yusuke Hirasawa, Tomoko Tanaka, Shiro Hirasawa, Chin Piow Wong, Nahoko Uchiyama, Toshio Kaneda, Yukihiro Goda, Hiroshi Morita

Erschienen in: Journal of Natural Medicines | Ausgabe 1/2022

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Abstract

Cliniatines A–C (1–3), three new Amaryllidaceae alkaloids, consisting of 2,6-dimetylpyridine and lycorine-type and/or galanthamine-type were isolated from Clivia miniata (Lindl.) Bosse. The structures and absolute configurations of 1–3 were elucidated based on spectroscopic data and chemical correlation. Cliniatines A–C showed moderate inhibitory activity against acetylcholinesterase.

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Metadaten
Titel
Cliniatines A–C, new Amaryllidaceae alkaloids from Clivia miniata, inhibiting Acetylcholinesterase
verfasst von
Yusuke Hirasawa
Tomoko Tanaka
Shiro Hirasawa
Chin Piow Wong
Nahoko Uchiyama
Toshio Kaneda
Yukihiro Goda
Hiroshi Morita
Publikationsdatum
22.09.2021
Verlag
Springer Singapore
Erschienen in
Journal of Natural Medicines / Ausgabe 1/2022
Print ISSN: 1340-3443
Elektronische ISSN: 1861-0293
DOI
https://doi.org/10.1007/s11418-021-01570-6

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