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Erschienen in:

01.11.2019 | Evidence-Based Medicine, Clinical Trials and Their Interpretations (L. Roever, Section Editor)

Effect of Aerobic Exercise on Peak Oxygen Consumption, VE/VCO₂ Slope, and Health-Related Quality of Life in Patients with Heart Failure with Preserved Left Ventricular Ejection Fraction: a Systematic Review and Meta-Analysis

verfasst von: Mansueto Gomes-Neto, André Rodrigues Durães, Lino Sergio Rocha Conceição, Leonardo Roever, Tong Liu, Gary Tse, Giuseppe Biondi-Zoccai, Ana Lucia Barbosa Goes, Iura Gonzalez Nogueira Alves, Øyvind Ellingsen, Vitor Oliveira Carvalho

Erschienen in: Current Atherosclerosis Reports | Ausgabe 11/2019

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Abstract

Purpose of Review

The aim of this study was to determine the effects of aerobic exercise on peak oxygen uptake (peak VO₂), minute ventilation/carbon dioxide production (VE/VCO₂ slope), and health-related quality of life (HRQoL) among patients with heart failure (HF) and preserved ejection fraction (HFpEF).

Recent Findings

We conducted a Cochrane Library, MEDLINE/PubMed, Physiotherapy Evidence Database, and SciELO search (from 1985 to May 2019) for randomized controlled trials that evaluated the effects of aerobic exercise in HFpEF patients. We calculated the mean differences (MD) and 95% confidence interval (CI). Ten intervention studies were included providing a total of 399 patients. Compared with control, aerobic exercise resulted in improvement in peak VO₂ MD 1.9 mL kg⁻¹ min⁻¹ (95% CI 1.3 to 2.5; N = 314) and HRQoL measured by Minnesota Living with Heart Failure MD 5.4 (95% CI − 10.5 to − 0.2; N = 256). No significant difference in VE/VCO₂ slope was found between participants in the aerobic exercise group and the control group. The quality of evidence for peak VO₂ and HRQoL was assessed as being moderate.

Summary

Aerobic exercise moderately improves peak VO₂ and HRQoL and should be considered a strategy of rehabilitation of HFpEF individuals.

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Titel: Effect of Aerobic Exercise on Peak Oxygen Consumption, VE/VCO2 Slope, and Health-Related Quality of Life in Patients with Heart Failure with Preserved Left Ventricular Ejection Fraction: a Systematic Review and Meta-Analysis
verfasst von: Mansueto Gomes-Neto
André Rodrigues Durães
Lino Sergio Rocha Conceição
Leonardo Roever
Tong Liu
Gary Tse
Giuseppe Biondi-Zoccai
Ana Lucia Barbosa Goes
Iura Gonzalez Nogueira Alves
Øyvind Ellingsen
Vitor Oliveira Carvalho
Publikationsdatum: 01.11.2019
Verlag: Springer US
Erschienen in: Current Atherosclerosis Reports / Ausgabe 11/2019
Print ISSN: 1523-3804
Elektronische ISSN: 1534-6242
DOI: https://doi.org/10.1007/s11883-019-0806-6

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