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The journal of nutrition, health & aging

Erschienen in:

14.12.2021 | Original Research

Sarcopenia Is Associated with Fecal Incontinence in Patients with Dysphagia: Implication for Anal Sarcopenia

verfasst von: S. Mizuno, Hidetaka Wakabayashi, M. Yamakawa, F. Wada, R. Kato, Y. Furiya, S. Nishioka, R. Momosaki

Erschienen in: The journal of nutrition, health & aging | Ausgabe 1/2022

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Abstract

Objectives

To examine the relationship between sarcopenia and fecal incontinence in patients with dysphagia.

Design

Cross-sectional study using the Japanese sarcopenic dysphagia database.

Setting

19 hospitals including 9 acute care hospitals, 8 rehabilitation hospitals, 2 long-term care hospitals, and 1 home visit rehabilitation center.

Participants

460 dysphagic patients, aged 20 years and older.

Measurements

Sarcopenia was diagnosed by the 2019 criteria of the Asian Working Group for Sarcopenia. Fecal incontinence was assessed by health care professionals at baseline according to the definition of the Japanese Practice Guidelines for Fecal Incontinence. We examined whether there was a significant difference between the rate of fecal incontinence in patients with/without sarcopenia. Age, sex, type of dwelling, Barthel index, Charlson comorbidity index (CCI), calf circumference, handgrip strength, body mass index, malnourishment, C-reactive protein level, serum albumin level, and delivery of enteral nutrition by nasogastric and/or gastrostomy tube were measured. To examine the relationship between sarcopenia and fecal incontinence, logistic regression analysis was performed with adjustments for age, sex, sarcopenia, CCI, enteral nutrition, and dwelling.

Results

The mean age of patients was 81 ± 10 years. Of the 460 study patients, 404 (88%) patients had sarcopenia and 104 had fecal incontinence (23%). The rate of fecal incontinence was higher in the sarcopenia group than the non-sarcopenia group (25% vs. 7%, P = 0.003). Logistic regression analysis showed that sarcopenia was independently associated with fecal incontinence (odds ratio: 3.114, 95% confidence interval: 1.045, 9.282).

Conclusion

The prevalence of fecal incontinence was 23% in patients with dysphagia. Sarcopenia was independently associated with fecal incontinence, which suggests the presence of anal sarcopenia. Defecation control should be assessed in patients with sarcopenia.

Chen LK, Woo J, Assantachai P, Auyeung TW, Chou MY, Iijima K, et al. Asian Working Group for Sarcopenia: 2019 Consensus Update on Sarcopenia Diagnosis and Treatment. J Am Med Dir Assoc. 2020;21:300–7.e2. doi:https://doi.org/10.1016/j.jamda.2019.12.012CrossRef

Makizako H, Nakai Y, Tomioka K, Taniguchi Y. Prevalence of sarcopenia defined using the Asia Working Group for Sarcopenia criteria in Japanese community-dwelling older adults: A systematic review and meta-analysis. Phys Ther Res. 2019;22:53–7. doi:https://doi.org/10.1298/ptr.R0005CrossRef

Churilov I, Churilov L, MacIsaac RJ, Ekinci EI. Systematic review and meta-analysis of prevalence of sarcopenia in post acute inpatient rehabilitation. Osteoporos Int. 2018;29:805–12. doi:https://doi.org/10.1007/s00198-018-4381-4CrossRef

Woo T, Yu S, Visvanathan R. Systematic Literature Review on the Relationship Between Biomarkers of Sarcopenia and Quality of Life in Older People. J Frailty Aging. 2016;5:88–99. doi:https://doi.org/10.14283/jfa.2016.93PubMed

Tsekoura M, Kastrinis A, Katsoulaki M, Billis E, Gliatis J. Sarcopenia and Its Impact on Quality of Life. Adv Exp Med Biol. 2017;987:213–8. doi:https://doi.org/10.1007/978-3-319-57379-3_19CrossRef

Maeda K, Yamana T, Takao Y, Mimura T, Katsuno H, Seki M, et al. Japanese Practice Guidelines for Fecal Incontinence Part 1-Definition, Epidemiology, Etiology, Pathophysiology and Causes, Risk Factors, Clinical Evaluations, and Symptomatic Scores and QoL Questionnaire for Clinical Evaluations-English Version. J Anus Rectum Colon. 2021;5:52–66. doi:https://doi.org/10.23922/jarc.2020-057CrossRef

Ng KS, Sivakumaran Y, Nassar N, Gladman MA. Fecal Incontinence: Community Prevalence and Associated Factors—A Systematic Review. Dis Colon Rectum. 2015;58:1194–209. doi:https://doi.org/10.1097/dcr.0000000000000514CrossRef

Meyer I, Richter HE. Impact of fecal incontinence and its treatment on quality of life in women. Womens Health (Lond). 2015;11:225–38. doi:https://doi.org/10.2217/whe.14.66CrossRef

Silva RRL, Coutinho JFV, Vasconcelos CTM, Vasconcelos Neto JA, Barbosa RGB, M BM, et al. Prevalence of sarcopenia in older women with pelvic floor dysfunction. Eur J Obstet Gynecol Reprod Biol. 2021;263:159–63. doi:https://doi.org/10.1016/j.ejogrb.2021.06.037CrossRef

10.

Parker-Autry C, Houston DK, Rushing J, Richter HE, Subak L, Kanaya AM, et al. Characterizing the Functional Decline of Older Women With Incident Urinary Incontinence. Obstet Gynecol. 2017;130:1025–32. doi:https://doi.org/10.1097/aog.0000000000002322CrossRef

11.

Bag Soytas R, Soytas M, Danacioglu YO, Citgez S, Yavuzer H, Can G, et al. Relationship between the types of urinary incontinence, handgrip strength, and pelvic floor muscle strength in adult women. Neurourol Urodyn. 2021;40:1532–8. doi:https://doi.org/10.1002/nau.24699CrossRef

12.

Yamashita S, Kawabata H, Deguchi R, Ueda Y, Higuchi M, Muraoka S, et al. Myosteatosis as a novel predictor of urinary incontinence after robot-assisted radical prostatectomy. Int J Urol. 2021. doi:https://doi.org/10.1111/iju.14704

13.

Asaoka D, Takeda T, Inami Y, Abe D, Shimada Y, Matsumoto K, et al. Association between the severity of constipation and sarcopenia in elderly adults: A single-center university hospital-based, cross-sectional study. Biomed Rep. 2021;14:2. doi:https://doi.org/10.3892/br.2020.1378PubMed

14.

Kido Y, Yoshimura Y, Wakabayashi H, Momosaki R, Nagano F, Bise T, et al. Sarcopenia is associated with incontinence and recovery of independence in urination and defecation in post-acute rehabilitation patients. Nutrition. 2021;91–92:111397. doi:https://doi.org/10.1016/j.nut.2021.111397CrossRef

15.

Wakabayashi H, Takahashi R, Murakami T. The Prevalence and Prognosis of Sarcopenic Dysphagia in Patients Who Require Dysphagia Rehabilitation. J Nutr Health Aging. 2019;23:84–8. doi:https://doi.org/10.1007/s12603-018-1117-2CrossRef

16.

Mizuno S, Wakabayashi H, Fujishima I, Kishima M, Itoda M, Yamakawa M, et al. Construction and Quality Evaluation of the Japanese Sarcopenic Dysphagia Database. J Nutr Health Aging. 2021;25:926–32. doi:https://doi.org/10.1007/s12603-021-1646-yCrossRef

17.

Kunieda K, Ohno T, Fujishima I, Hojo K, Morita T. Reliability and validity of a tool to measure the severity of dysphagia: the Food Intake LEVEL Scale. J Pain Symptom Manage. 2013;46:201–6. doi:https://doi.org/10.1016/j.jpainsymman.2012.07.020CrossRef

18.

Mahoney FI, Barthel DW. Functional evaluation: the Barthel index. Md State Med J. 1965;14:61–5.

19.

Quan H, Li B, Couris CM, Fushimi K, Graham P, Hider P, et al. Updating and validating the Charlson comorbidity index and score for risk adjustment in hospital discharge abstracts using data from 6 countries. Am J Epidemiol. 2011;173:676–82. doi:https://doi.org/10.1093/aje/kwq433CrossRef

20.

Cederholm T, Jensen GL, Correia M, Gonzalez MC, Fukushima R, Higashiguchi T, et al. GLIM criteria for the diagnosis of malnutrition — A consensus report from the global clinical nutrition community. J Cachexia Sarcopenia Muscle. 2019;10:207–17. doi:https://doi.org/10.1002/jcsm.12383CrossRef

21.

Lee TH, Lee JS, Kim J, Kim JO, Kim HG, Jeon SR, et al. Spontaneous Internal Anal Sphincter Relaxation During High-resolution Anorectal Manometry Is Associated With Peripheral Neuropathy and Higher Charlson Comorbidity Scores in Patients With Defecatory Disorders. J Neurogastroenterol Motil. 2020;26:362–9. doi:https://doi.org/10.5056/jnm19129CrossRef

22.

Majid HA, Emery PW, Whelan K. Definitions, attitudes, and management practices in relation to diarrhea during enteral nutrition: a survey of patients, nurses, and dietitians. Nutr Clin Pract. 2012;27:252–60. doi:https://doi.org/10.1177/0884533611431986CrossRef

23.

Pretlove SJ, Radley S, Toozs-Hobson PM, Thompson PJ, Coomarasamy A, Khan KS. Prevalence of anal incontinence according to age and gender: a systematic review and meta-regression analysis. Int Urogynecol J Pelvic Floor Dysfunct. 2006;17:407–17. doi:https://doi.org/10.1007/s00192-005-0014-5CrossRef

24.

Jacob L, Kostev K. Urinary and fecal incontinence in stroke survivors followed in general practice: A retrospective cohort study. Ann Phys Rehabil Med. 2020;63:488–94. doi:https://doi.org/10.1016/j.rehab.2019.12.007CrossRef

25.

Shiraishi A, Wakabayashi H, Yoshimura Y. Oral Management in Rehabilitation Medicine: Oral Frailty, Oral Sarcopenia, and Hospital-Associated Oral Problems. J Nutr Health Aging. 2020;24:1094–9. doi:https://doi.org/10.1007/s12603-020-1439-8CrossRef

26.

Nagano A, Wakabayashi H, Maeda K, Kokura Y, Miyazaki S, Mori T, et al. Respiratory Sarcopenia and Sarcopenic Respiratory Disability: Concepts, Diagnosis, and Treatment. J Nutr Health Aging. 2021;25:507–15. doi:https://doi.org/10.1007/s12603-021-1587-5CrossRef

27.

Nagano A, Nishioka S, Wakabayashi H. Rehabilitation Nutrition for Iatrogenic Sarcopenia and Sarcopenic Dysphagia. J Nutr Health Aging. 2019;23:256–65. doi:https://doi.org/10.1007/s12603-018-1150-1CrossRef

28.

Mori T, Wakabayashi H, Ogawa N, Fujishima I, Oshima F, Itoda M, et al. The Mass of Geniohyoid Muscle Is Associated with Maximum Tongue Pressure and Tongue Area in Patients with Sarcopenic Dysphagia. J Nutr Health Aging. 2021;25:356–60. doi:https://doi.org/10.1007/s12603-020-1528-8CrossRef

29.

Shimizu A, Maeda K, Wakabayashi H, Nishioka S, Ohno T, Nomoto A, et al. Sarcopenic Dysphagia with Low Tongue Pressure Is Associated with Worsening of Swallowing, Nutritional Status, and Activities of Daily Living. J Nutr Health Aging. 2021;25:883–8. doi:https://doi.org/10.1007/s12603-021-1641-3CrossRef

30.

Laurberg S, Swash M. Effects of aging on the anorectal sphincters and their innervation. Dis Colon Rectum. 1989;32:737–42. doi:https://doi.org/10.1007/bf02562120CrossRef

31.

Frudinger A, Halligan S, Bartram CI, Price AB, Kamm MA, Winter R. Female anal sphincter: age-related differences in asymptomatic volunteers with high-frequency endoanal US. Radiology. 2002;224:417–23. doi:https://doi.org/10.1148/radiol.2242010985CrossRef

32.

Kaneko T, Nemoto T, Funahashi K, Koike J, Shibuya K, Kaneko H. Differences in innervated neurons of the internal anal sphincter based on age and sex: A histological study. Geriatr Gerontol Int. 2018;18:495–500. doi:https://doi.org/10.1111/ggi.13193CrossRef

33.

Dias N, Zhang C, Li X, Neshatian L, Orejuela FJ, Zhang Y. Neural control properties of the external anal sphincter in young and elderly women. Neurourol Urodyn. 2019;38:1828–33. doi:https://doi.org/10.1002/nau.24108CrossRef

34.

Kakehi S, Wakabayashi H, Inuma H, Inose T, Shioya M, Aoyama Y, et al. Rehabilitation Nutrition and Exercise Therapy for Sarcopenia. World J Mens Health. 2021. doi:https://doi.org/10.5534/wjmh.200190

35.

Mizuno S, Wakabayashi H, Wada F. Rehabilitation nutrition for individuals with frailty, disability, sarcopenic dysphagia, or sarcopenic respiratory disability. Curr Opin Clin Nutr Metab Care. 2021. doi:https://doi.org/10.1097/mco.0000000000000787

36.

Scott KM. Pelvic floor rehabilitation in the treatment of fecal incontinence. Clin Colon Rectal Surg. 2014;27:99–105. doi:https://doi.org/10.1055/s-0034-1384662CrossRef

37.

Mazur-Bialy AI, Kołomańska-Bogucka D, Opławski M, Tim S. Physiotherapy for Prevention and Treatment of Fecal Incontinence in Women-Systematic Review of Methods. J Clin Med. 2020;9:3255. doi:https://doi.org/10.3390/jcm9103255CrossRef

38.

Maeda K, Mimura T, Yoshioka K, Seki M, Katsuno H, Takao Y, et al. Japanese Practice Guidelines for Fecal Incontinence Part 2-Examination and Conservative Treatment for Fecal Incontinence- English Version. J Anus Rectum Colon. 2021;5:67–83. doi:https://doi.org/10.23922/jarc.2020-079CrossRef

Titel: Sarcopenia Is Associated with Fecal Incontinence in Patients with Dysphagia: Implication for Anal Sarcopenia
verfasst von: S. Mizuno
Hidetaka Wakabayashi
M. Yamakawa
F. Wada
R. Kato
Y. Furiya
S. Nishioka
R. Momosaki
Publikationsdatum: 14.12.2021
Verlag: Springer Paris
Erschienen in: The journal of nutrition, health & aging / Ausgabe 1/2022
Print ISSN: 1279-7707
Elektronische ISSN: 1760-4788
DOI: https://doi.org/10.1007/s12603-021-1711-6

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Abstract

Objectives

Design

Setting

Participants

Measurements

Results

Conclusion

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