Introduction
Expectancies to be met by MRI of the lung
Role of MRI | Situation/pathological condition | i.v. contrast |
---|---|---|
Situations that warrant the use of MRI | Children | Optional |
Pregnant women | Optional | |
Young patients with need for repeated imaging of the lungs | Optional | |
To replace CT if contrast media are contra-indicated | Optional | |
Scientific studies | Optional | |
Pharmaceutical trials | Optional | |
In discussion: lung cancer screening | Optional | |
Indications covered by MRI | Complicated thoracic mass (mediastinum and chest wall invasion)a | Optional |
with advantages over CT | Differentiation of atelectasis and pulmonary massa | Optional |
Differentiation of mediastinal masses | Optional | |
Evaluation of respiratory mechanics | No | |
Diagnosis of pulmonary perfusion deficits (embolism, hypoxic vasoconstriction) | Yes | |
Cystic fibrosis (with perfusion study)a | Yes | |
Indications covered by MRI | Pneumonia | No |
as effectively as with CT | Atelectasis | No |
(if situation warrants use of MRI) | Cystic fibrosis (without perfusion study)a | No |
Tuberculosis | No | |
Pulmonary nodules (> 3 mm) | No | |
Sarcoidosis | Optional | |
Acute and chronic pulmonary embolisma | Yes | |
Abnormalities of pulmonary venous drainage | Yes | |
Pulmonary arterial aneurysm | Yes | |
Lung sequestration | Yes | |
AV malformation (M. Osler) | Yes | |
Staging of lung cancer | Yes | |
Vasculitis (e.g. Wegener’s) | Yes | |
Pleural effusion of unclear origin | Yes | |
Mesothelioma | Yes | |
Indications covered less effectively | Pulmonary miconodules (< 3 mm) | Optional |
than with CT | Interstitial lung diseasea | Optional |
Emphysema/COPD* | Optional |
Sequence type | Features or variations | Vendor–specific acronyms | Respiration manoeuvre | Spatial resolution | Temporal resolution | Particular use for lung MRI (pathology) | Protocol suggestiona | ||||
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Siemens | Philips | GE | Hitachi | Toshiba | (Typical acquisition time) | (Typical pixel size) | (s per slice or volume) | ||||
3D gradient echo T1-weighted | Volume interpolation (ce with fat saturation) | VIBE | THRIVE | LAVA | TIGRE | Quick3D | Breath–hold (21 s) | High (1.5 × 1.5 mm) | Low | Pulmonary nodules, masses, airways | G, T, V |
Max. spatial resolution for angiography | Flash 3D | FFE | SPGR | RF spoiled SARGE | FE, FFE | Breath-hold (21 s) | High (1.2 × 1 mm) | Low | High resolution angiogram (embolism AVM) | V | |
Echo sharing | TWIST | TRAK | TRICKS | TRAQ | DRKS | Breath-hold or shallow breathing | Low (3.5 × 2 mm) | High (< 1.5 s/vol) | First pass lung perfusion (embolism, hypoxic vasoconstriction) | V, (T) | |
Fast spin echo T2-weighted | Half Fourier acquisition | HASTE | Halfscan FSE | ½ NEX FSE | Half scan Single shot FSE | AFI RO | Multiple breath-hold (2 × 20 s) | Low (1.8 × 1.8 mm) | High | Infiltrates | G, T |
Rotating phase encoding | BLADE | MultiVane | PROPELLER | RADAR | JET | Multiple breath hold (4-5 × 20 s) | Moderate (1.8 × 1.5 mm) | Moderate | Nodules and masses | G, T | |
Respir. triggered, high res. | TSE-rt | TSE | FSE | FSE | FSE | Respiration triggered (5-10 min) | Moderate-high (1.3 × 1 mm) | Low | Masses | (G), (T) | |
Fat saturated | TSE fs BLADE fs | TSE fs or MultiVane | FSE fs or PROPELLER | FSE fs or RADAR | FSE fs or JET fs | Multiple breath-hold(4-5 × 20 s) or respiration triggered (4-8 min) | Moderate (1.8 × 1.5 mm) | Moderate | Lymph nodes bone metastases | G, T | |
Short tau inversion recovery | Fast spin echo | STIR | STIR | STIR | STIR | STIR | |||||
Diffusion weighted imaging (DWI) | Echo planar imaging or other fast technique | REVEAL (DWI) | DWIBS (DWI) | Whole Body Diffusion (DWI) | DWI | Body Vision (DWI) | Multiple breath-hold (3-4 × 20 s) or respiration triggered (4-5 min) | Low (3 × ×2 mm) | Low | Nodules and masses | T |
Steady state GRE | T1/T2 contrast | TrueFISP | bFFE | FIESTA | BASG | TrueSSFP | Free breathing (60 s) or instructed br. manoeuvres | Moderate (2.4 × 1.6 mm) | High (< 0.5 s/sl.) | Pulmonary embolism | G, T, V |
Respiration mechanics | T |
Sequence combination dedicated to clinical problems | Patients compliant, able to hold breath for 20 s | i.v. contrast | Alternative approach in patients unable to hold breath for 20s, e.g. children | ||||||
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General question (15 min) | Thoracic mass (20 min) | Pulmonary embolism, AVM (15 min) | Mass w/ vessel invasion (25 min) | Sequence selection | Slice orientation | Slice thickness | Respiration manoeuvre | ||
X | X | X | 3D gradient echo T1-w. | Transverse | 4 mm (interpolated) | Breath-hold | no | Not available/to be developed | |
X | X | X | Fast spin echo T2-w., half Fourier | Coronal | 6-8 mm | Breath-hold | No | Triggered or non triggered acquisition in free breathing (0-5 min increase in acquisition time) | |
X | X | X | X | Steady state GRE | Coronal | 4-6 mm | Free breathing | No | No change needed |
X | X | X | Fast spin echo T2-w., rotating phase encoding | Coronal (non-fat sat.) | 4-6 mm | Breath-hold | No | Triggered acquisition in free breathing (5 min increase in acquisition time) | |
X | (X) | (X) | Fast spin echo T2-w. rotating phase encoding | Transverse (fat sat. or IR) | 4-6 mm | Breath-hold | No | Triggered acquisition in free breathing (5 min increase in acquisition time) | |
X | (X) | Diffusion weighted imaging | Multi breath-hold | No | Triggered acquisition in free breathing (5 min. increase in acquisition time) | ||||
X | X | 3D gradient echo T1-w. dynamic angio | Coronal | 5 mm | Breath-hold | Yes | Acquisition in shallow free breathing possible (no increase in acquisition time) | ||
X | X | 3D gradient echo T1-w. max. spatial res. angio | Coronal | 1.5-3 mm | Breath-hold | Yes | Not available/to be developed | ||
X | X | X | 3D gradient echo T1-w. fat saturated | Transverse | 4 mm (interpolated) | Breath-hold | Yes | Not available/to be developed | |
X | 3D gradient echo T1-w. fat saturated | Coronal | 4 mm (interpolated) | Breath-hold | Yes | Not available/to be developed |
½ NEX | Half Fourier acquisition (GE) |
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2D | Two-dimensional (single image in one plane) |
2D + t | Temporally resolved (dynamic) imaging in a single plane (used to differentiate from 3D for spatially resolved acqisitions) |
3D | Three-dimensional (spatial resolution) |
3D + t | Temporally resolved (dynamic) imaging in multiple volumes |
4D | Four-dimensional (with spatial and temporal resolution, a term often used as synonym to 3D + t) |
AFI RO | Advanced Fourier imaging in read out (partial/half Fourier acquisition sequence; Toshiba) |
ASL | Arterial spin labeling |
BASG | Balanced spoiled steady state acquisition rewinded gradient (gradient echo sequence with steady state acquisition; Hitachi) |
bFFE | Balanced fast field echo (gradient echo sequence with steady state acquisition; Philips) |
BLADE | Brand name/not an acronym (rotating phase encoding sequence; Siemens) |
Body Vision | Brand name/not an acronym (diffusion weighted imaging sequence; Toshiba) |
ce | Contrast enhanced |
CT | Computed tomography |
DCE MRI | Dynamic contrast enhanced MRI (can be 2D + t or 3D + t) |
DRKS | Different rate k-space sampling (temporally resolved 3D gradient echo sequence with temporal resolution (3D + t) achieved by echo sharing; Toshiba) |
DWI | diffusion-weighted imaging |
DWIBS | Diffusion-Weighted whole body Imaging with body BBackground signal Suppression (diffusion-weighted imaging sequence; Philips) |
FE | Field echo (gradient echo sequence syn. to flash; Toshiba, Philips) |
FFE | Fast field echo (gradient echo sequence syn. to flash; Toshiba, Philips) |
FIESTA | Fast imaging employing steady state acquisition (gradient echo sequence with steady state acquisition; GE) |
Flash | Fast low angle shot (the basic technique for GE sequences; Siemens) |
FSE | Fast spin echo (sequence; GE, Hitachi, Toshiba) |
GE | Gradient echo (gradient echo sequence) |
GRE | Gradient recalled echo (gradient echo sequence) |
Half scan | Half Fourier acquisition technique (Philips, Hitachi) |
HASTE | Half Fourier short turbo spin echo (sequence; Siemens) |
JET | Brand name/not an acronym (rotating phase encoding sequence; Toshiba) |
LAVA | Liver acquisition with volume acceleration (a 3D gradient echo sequence with volume interpolation and RF fat saturation; GE) |
MRA | Magnetic resonance angiography |
MRI | Magnetic resonance imaging (MR imaging) |
MultiVane | Brand name/not an acronym (rotating phase encoding sequence; Philips) |
PROPELLER | Periodically Rotated Overlapping Parallel Lines with Enhanced Reconstruction (rotating phase encoding sequence; GE) |
Quick3D | 3D gradient echo with volume interpolation (sequence; Toshiba) |
RADAR | Radial acquisition regime (rotating phase encoding sequence; Hitachi) |
REVEAL | Brand name/not an acronym (diffusion weighted imaging sequence; Siemens) |
RF | Radio frequency |
SARGE | Spoiled steady state acquisition rewinded gradient echo (sequence syn. to flash; Hitachi) |
SF6 | Sulphur hexafluoride |
SPGR | Spoiled gradient echo recalled (sequence syn. to flash; GE) |
SSFP | Steady state free precession (gradient echo sequence with steady state acquisition) |
STIR | Short tau inversion recovery (sequence) |
T | Tesla (unit for field strength) |
T1, T2 | Time constants for signal decay in MRI |
T1-w./T2-w. | Sequences producing images with T1- or T2-weighted contrast |
THRIVE | T1 high resolution isotropic volume excitation (a 3D gradient echo sequence with volume interpolation and RF fat saturation; Philips) |
TIGRE | Brand name/not an acronym (a 3D gradient echo sequence with volume interpolation and RF fat saturation; Hitachi) |
TRAK | Time-resolved angiography using keyhole (a temporally resolved 3D gradient echo sequence with temporal resolution (3D + t) achieved by echo sharing; Philips) |
TRICKS | Time-resolved imaging of contrast kinetics (a temporally resolved 3D gradient echo sequence with temporal resolution (3D + t) achieved by echo sharing; GE) |
TrueFISP | True fast imaging with steady state precession (gradient echo sequence with steady state acquisition; Siemens) |
TrueSSFP | True steady state free precession (gradient echo sequence with steady state acquisition; Toshiba) |
TSE | Turbo spin echo (fast spin echo sequence; Siemens, Philips) |
TWIST | Time-resolved angiography with stochastic trajectories (temporally resolved 3D gradient echo sequence with temporal resolution (3D + t) achieved by echo sharing; Siemens) |
VIBE | Volumetric interpolated breath hold examination (a 3D gradient echo sequence with volume interpolation and RF fat saturation; Siemens) |