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Journal of Cachexia, Sarcopenia and Muscle
Erschienen in: Journal of Cachexia, Sarcopenia and Muscle 2/2013

01.06.2013 | Review

Cancer cachexia: impact, mechanisms and emerging treatments

verfasst von: Vanessa C. Vaughan, Peter Martin, Paul A. Lewandowski

Erschienen in: Journal of Cachexia, Sarcopenia and Muscle | Ausgabe 2/2013

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Abstract

Many forms of cancer present with a complex metabolic profile characterised by loss of lean body mass known as cancer cachexia. The physical impact of cachexia contributes to decreased patient quality of life, treatment success and survival due to gross alterations in protein metabolism, increased oxidative stress and systemic inflammation. The psychological impact also contributes to decreased quality of life for both patients and their families. Combination therapies that target multiple pathways, such as eicosapentaenoic acid administered in combination with exercise, appetite stimulants, antioxidants or anti-inflammatories, have potential in the treatment of this complex syndrome and require further development.
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Metadaten
Titel
Cancer cachexia: impact, mechanisms and emerging treatments
verfasst von
Vanessa C. Vaughan
Peter Martin
Paul A. Lewandowski
Publikationsdatum
01.06.2013
Verlag
Springer-Verlag
Erschienen in
Journal of Cachexia, Sarcopenia and Muscle / Ausgabe 2/2013
Print ISSN: 2190-5991
Elektronische ISSN: 2190-6009
DOI
https://doi.org/10.1007/s13539-012-0087-1

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