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01.11.2015 | Review

Considering treatment of male genital schistosomiasis as a tool for future HIV prevention: a systematic review

verfasst von: Chalotte Willemann Stecher, Per Kallestrup, Eyrun Floerecke Kjetland, Birgitte Vennervald, Eskild Petersen

Erschienen in: International Journal of Public Health | Ausgabe 7/2015

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Abstract

Objectives

Male genital schistosomiasis (MGS) is a neglected manifestation of Schistosoma haematobium infection with ignored implications on reproductive health and a differential diagnosis to sexually transmitted infections in endemic regions. MGS may have associations with HIV transmission and acquisition, and treatment could be a neglected chance of HIV prevention. This review summarizes current knowledge on epidemiology, clinical manifestations, diagnosis and treatment of MGS as a hypothesized risk factor for HIV transmission. Future research areas of global interest are suggested.

Methods

PubMed published literature was reviewed based on the MOOSE guidelines. All publications on MGS were included regardless of publication year and study design. Furthermore, all publications were searched for information on possible HIV association.

Results

The 40 identified publications related to MGS were dominated by case reports and observational studies. No randomized clinical trials have been conducted to date, and very scant information related to possible associations with HIV transmission was presented.

Conclusions

Clinical, randomized studies and epidemiological studies covering the possible association between MGS and HIV are urgently needed. Furthermore, field diagnostic tools should be developed and future mass treatment programs should include adults to reduce morbidity and prevent HIV acquisition.

Systematic review registration number

CRD42015016252.

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Titel: Considering treatment of male genital schistosomiasis as a tool for future HIV prevention: a systematic review
verfasst von: Chalotte Willemann Stecher
Per Kallestrup
Eyrun Floerecke Kjetland
Birgitte Vennervald
Eskild Petersen
Publikationsdatum: 01.11.2015
Verlag: Springer Basel
Erschienen in: International Journal of Public Health / Ausgabe 7/2015
Print ISSN: 1661-8556
Elektronische ISSN: 1661-8564
DOI: https://doi.org/10.1007/s00038-015-0714-7

Springer Medizin

Abstract

Objectives

Methods

Results

Conclusions

Systematic review registration number

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