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01.05.2013 | Original article

¹²⁵I Seed implant brachytherapy for the treatment of parotid gland cancers in children and adolescents

verfasst von: L. Zheng, MD, DDS, J. Zhang, MD, DDS, T. Song, MD, DDS, Prof. J. Zhang, MD, DDS, G. Yu, MD, DDS, Y. Zhang, MD, DDS

Erschienen in: Strahlentherapie und Onkologie | Ausgabe 5/2013

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Abstract

Background and purpose

There is a lack of optimal treatment strategies for managing salivary gland cancers in children and adolescents. This study is aimed at assessing the effect of ¹²⁵I seed implantation for the treatment of parotid cancers in children and adolescents.

Patients and methods

A total of 12 patients younger than 16 years with parotid gland malignant tumors underwent ¹²⁵I seed implant brachytherapy between October 2003 and November 2008. All patients were assessed after treatment and at the local tumor control appointments. Facial nerve function, maxillofacial development, and radioactive side-effects were assessed.

Results

The follow-up period ranged from 41–104 months. One patient with T4b died of pulmonary metastasis. The other patients were alive during the follow-up period. There were no serious radiation-related complications. The treatment did not affect facial nerve function and dentofacial growth in any of the children.

Conclusion

For parotid gland cancers in children, ¹²⁵I seed implant brachytherapy may be an acceptable treatment without serious complications and with satisfactory short-term effects.

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Titel: 125I Seed implant brachytherapy for the treatment of parotid gland cancers in children and adolescents
verfasst von: L. Zheng, MD, DDS
J. Zhang, MD, DDS
T. Song, MD, DDS
Prof. J. Zhang, MD, DDS
G. Yu, MD, DDS
Y. Zhang, MD, DDS
Publikationsdatum: 01.05.2013
Verlag: Springer-Verlag
Erschienen in: Strahlentherapie und Onkologie / Ausgabe 5/2013
Print ISSN: 0179-7158
Elektronische ISSN: 1439-099X
DOI: https://doi.org/10.1007/s00066-013-0313-6

Springer Medizin

¹²⁵I Seed implant brachytherapy for the treatment of parotid gland cancers in children and adolescents