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Diabetologia

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01.05.2004 | Commentary

Is “Cushing’s disease of the omentum” an affliction of mouse and men?

verfasst von: B. R. Walker

Erschienen in: Diabetologia | Ausgabe 5/2004

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Excerpt

Adipose tissue is increasingly recognised as an “endocrine factory”, releasing many newly identified hormones such as leptin, resistin, adiponectin etc. These discoveries have stirred enthusiasm for investigating “older” hormones that are also released from adipose tissue. One of these is cortisol, putatively generated in excess in omental adipose tissue in obese people [1], increasing glucocorticoid receptor activation in adipose and being released into the portal circulation to act also in the liver and exacerbate the metabolic complications of the obesity. …

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Titel: Is “Cushing’s disease of the omentum” an affliction of mouse and men?
verfasst von: B. R. Walker
Publikationsdatum: 01.05.2004
Verlag: Springer-Verlag
Erschienen in: Diabetologia / Ausgabe 5/2004
Print ISSN: 0012-186X
Elektronische ISSN: 1432-0428
DOI: https://doi.org/10.1007/s00125-004-1390-y

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