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Erschienen in: World Journal of Surgery 10/2013

01.10.2013

Laparoscopy-Assisted Distal Gastrectomy Versus Open Distal Gastrectomy. A Prospective Randomized Single-Blind Study

verfasst von: Shuji Takiguchi, Yoshiyuki Fujiwara, Makoto Yamasaki, Hiroshi Miyata, Kiyokazu Nakajima, Mitsugu Sekimoto, Masaki Mori, Yuichiro Doki

Erschienen in: World Journal of Surgery | Ausgabe 10/2013

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Abstract

Background

Laparoscopy-assisted distal gastrectomy (LADG) is generally considered superior to open distal gastrectomy (ODG) with regard to postoperative quality-of-life. Differences in postoperative pain may exist due to recent pain control techniques including epidural anesthesia. There is little evidence for this difference. In this article we report the results of our randomized single-blind study in LADG versus ODG. The aim of the present study was to evaluate differences in postoperative physical activity between LADG and ODG.

Methods

Forty patients with early gastric cancer (stage IA and IB) were registered in this randomized study. For strict evaluation, patients were not told about the type of operation until postoperative day 7. Postoperative physical activity was evaluated objectively by Active Tracer, which records the cumulative acceleration over a 24 h period to investigate differences in postoperative recovery. Questionnaire and visual analog scale score related to postoperative pain were also investigated.

Results

Significant differences were observed with a more favorable outcome noted in the LADG group with respect to intraoperative blood loss (P < 0.001), total amount of pain rescue (P < 0.001), wound size (P < 0.001), postoperative hospital stay (P < 0.001), and inflammatory parameters (C-reactive protein, SaO2, and duration of febrile period) (P < 0.001). Cumulative physical recovery to 70 % of the preoperative level was significantly shorter (by 3 days, P < 0.001) in the LADG group.

Conclusions

Comparison of LADG and ODG for patients with early gastric cancer showed favorable outcome and earlier recovery of physical activity in the LADG group.
Literatur
1.
Zurück zum Zitat Kitano S, Iso Y, Moriyama M et al (1994) Laparoscopy-assisted Billroth I gastrectomy. Surg Laparosc Endosc 4:146–148PubMed Kitano S, Iso Y, Moriyama M et al (1994) Laparoscopy-assisted Billroth I gastrectomy. Surg Laparosc Endosc 4:146–148PubMed
2.
Zurück zum Zitat Adachi Y, Shiraishi N, Shiromizu A et al (2000) Laparoscopy-assisted Billroth I gastrectomy compared with conventional open gastrectomy. Arch Surg 135:806–810PubMedCrossRef Adachi Y, Shiraishi N, Shiromizu A et al (2000) Laparoscopy-assisted Billroth I gastrectomy compared with conventional open gastrectomy. Arch Surg 135:806–810PubMedCrossRef
3.
Zurück zum Zitat Reyes CD, Weber KJ, Gagner M et al (2001) Laparoscopic vs open gastrectomy: a retrospective review. Surg Endosc 15:928–931PubMedCrossRef Reyes CD, Weber KJ, Gagner M et al (2001) Laparoscopic vs open gastrectomy: a retrospective review. Surg Endosc 15:928–931PubMedCrossRef
4.
Zurück zum Zitat Shimizu S, Uchiyama A, Mizumoto K et al (2000) Laparoscopically assisted distal gastrectomy for early gastric cancer: is it superior to open surgery? Surg Endosc 14:27–31PubMedCrossRef Shimizu S, Uchiyama A, Mizumoto K et al (2000) Laparoscopically assisted distal gastrectomy for early gastric cancer: is it superior to open surgery? Surg Endosc 14:27–31PubMedCrossRef
5.
Zurück zum Zitat Yano H, Monden T, Kinuta M et al (2001) The usefulness of laparoscopy-assisted distal gastrectomy in comparison with that of open distal gastrectomy for early gastric cancer. Gastric Cancer 4:93–97PubMedCrossRef Yano H, Monden T, Kinuta M et al (2001) The usefulness of laparoscopy-assisted distal gastrectomy in comparison with that of open distal gastrectomy for early gastric cancer. Gastric Cancer 4:93–97PubMedCrossRef
6.
Zurück zum Zitat Hayashi H, Ochiai T, Shimada H et al (2005) Prospective randomized study of open versus laparoscopy-assisted distal gastrectomy with extraperigastric lymph node dissection for early gastric cancer. Surg Endosc 19:1172–1176PubMedCrossRef Hayashi H, Ochiai T, Shimada H et al (2005) Prospective randomized study of open versus laparoscopy-assisted distal gastrectomy with extraperigastric lymph node dissection for early gastric cancer. Surg Endosc 19:1172–1176PubMedCrossRef
7.
Zurück zum Zitat Kitano S, Shiraishi N, Fujii K et al (2002) A randomized controlled trial comparing open vs laparoscopy-assisted distal gastrectomy for the treatment of early gastric cancer: an interim report. Surgery 131:S306–S311PubMedCrossRef Kitano S, Shiraishi N, Fujii K et al (2002) A randomized controlled trial comparing open vs laparoscopy-assisted distal gastrectomy for the treatment of early gastric cancer: an interim report. Surgery 131:S306–S311PubMedCrossRef
8.
Zurück zum Zitat Wong DL, Baker CM (1988) Pain in children: comparison of assessment scales. Pediatr Nurs 14:9–17PubMed Wong DL, Baker CM (1988) Pain in children: comparison of assessment scales. Pediatr Nurs 14:9–17PubMed
9.
Zurück zum Zitat Squirrell DM, Majeed AW, Troy G et al (1998) A randomized, prospective, blinded comparison of postoperative pain, metabolic response, and perceived health after laparoscopic and small incision cholecystectomy. Surgery 12:485–495CrossRef Squirrell DM, Majeed AW, Troy G et al (1998) A randomized, prospective, blinded comparison of postoperative pain, metabolic response, and perceived health after laparoscopic and small incision cholecystectomy. Surgery 12:485–495CrossRef
10.
Zurück zum Zitat Majeed AW, Troy G, Nicholl JP et al (1996) Randomised, prospective, single-blind comparison of laparoscopic versus small-incision cholecystectomy. Lancet 13(347):989–994CrossRef Majeed AW, Troy G, Nicholl JP et al (1996) Randomised, prospective, single-blind comparison of laparoscopic versus small-incision cholecystectomy. Lancet 13(347):989–994CrossRef
11.
Zurück zum Zitat Kawamura H, Homma S, Yokota R et al (2008) Assessment of pain by face scales after gastrectomy: comparison of laparoscopically assisted gastrectomy and open gastrectomy. Surg Endosc 23:991–995PubMedCrossRef Kawamura H, Homma S, Yokota R et al (2008) Assessment of pain by face scales after gastrectomy: comparison of laparoscopically assisted gastrectomy and open gastrectomy. Surg Endosc 23:991–995PubMedCrossRef
12.
Zurück zum Zitat Nomura A, Kakinoki S, Takechi S et al (1996) Physical activity affects ambulatory blood pressure in normotensive and hypertensive elderly people. Cardiol Elderly 4:101–104 Nomura A, Kakinoki S, Takechi S et al (1996) Physical activity affects ambulatory blood pressure in normotensive and hypertensive elderly people. Cardiol Elderly 4:101–104
13.
Zurück zum Zitat Tsukioka M, Kamo C, Kaneko M et al (1995) The effect of nipradilol on essential hypertension with cerebrovascular disease assessed by 24-hour ambulatory blood pressure monitoring [in Japanese]. Ther Res 16:1161–1169 Tsukioka M, Kamo C, Kaneko M et al (1995) The effect of nipradilol on essential hypertension with cerebrovascular disease assessed by 24-hour ambulatory blood pressure monitoring [in Japanese]. Ther Res 16:1161–1169
14.
Zurück zum Zitat Steele BG, Holt L, Belza B et al (2000) Quantitating physical activity in COPD using a triaxial accelerometer. Chest 117:1359–1367PubMedCrossRef Steele BG, Holt L, Belza B et al (2000) Quantitating physical activity in COPD using a triaxial accelerometer. Chest 117:1359–1367PubMedCrossRef
15.
Zurück zum Zitat Inoue Y, Kimura T, Noro H et al (2003) Is laparoscopic colorectal surgery less invasive than classical open surgery? Surg Endosc 17:1269–1273PubMedCrossRef Inoue Y, Kimura T, Noro H et al (2003) Is laparoscopic colorectal surgery less invasive than classical open surgery? Surg Endosc 17:1269–1273PubMedCrossRef
16.
Zurück zum Zitat Kim YW, Baik YH, Yun YH et al (2008) Improved quality of life outcomes after laparoscopy-assisted distal gastrectomy for early gastric cancer: results of a prospective randomized clinical trial. Ann Surg 248:721–727PubMedCrossRef Kim YW, Baik YH, Yun YH et al (2008) Improved quality of life outcomes after laparoscopy-assisted distal gastrectomy for early gastric cancer: results of a prospective randomized clinical trial. Ann Surg 248:721–727PubMedCrossRef
17.
Zurück zum Zitat Clinical Outcomes of Surgical Therapy Study Group (2004) A comparison of laparoscopically assisted and open colectomy for colon cancer. N Engl J Med 350:2050–2059CrossRef Clinical Outcomes of Surgical Therapy Study Group (2004) A comparison of laparoscopically assisted and open colectomy for colon cancer. N Engl J Med 350:2050–2059CrossRef
18.
Zurück zum Zitat Lacy AM, Garcia-Valdecasas JC, Delgado S et al (2002) Laparoscopy-assisted colectomy versus open colectomy for treatment of non-metastatic colon cancer: a randomised trial. Lancet 359:2224–2229PubMedCrossRef Lacy AM, Garcia-Valdecasas JC, Delgado S et al (2002) Laparoscopy-assisted colectomy versus open colectomy for treatment of non-metastatic colon cancer: a randomised trial. Lancet 359:2224–2229PubMedCrossRef
19.
Zurück zum Zitat Weeks JC, Nelson H, Gelber S et al (2002) Short-term quality-of-life outcomes following laparoscopic-assisted colectomy vs open colectomy for colon cancer: a randomized trial. JAMA 287:321–328PubMedCrossRef Weeks JC, Nelson H, Gelber S et al (2002) Short-term quality-of-life outcomes following laparoscopic-assisted colectomy vs open colectomy for colon cancer: a randomized trial. JAMA 287:321–328PubMedCrossRef
20.
Zurück zum Zitat Huscher CG, Mingoli A, Sgarzini G et al (2005) Laparoscopic versus open subtotal gastrectomy for distal gastric cancer: five-year results of a randomized prospective trial. Ann Surg 241:232–237PubMedCrossRef Huscher CG, Mingoli A, Sgarzini G et al (2005) Laparoscopic versus open subtotal gastrectomy for distal gastric cancer: five-year results of a randomized prospective trial. Ann Surg 241:232–237PubMedCrossRef
21.
Zurück zum Zitat Mochiki E, Kamiyama Y, Aihara R et al (2005) Laparoscopic assisted distal gastrectomy for early gastric cancer: five years’ experience. Surgery 137:317–322PubMedCrossRef Mochiki E, Kamiyama Y, Aihara R et al (2005) Laparoscopic assisted distal gastrectomy for early gastric cancer: five years’ experience. Surgery 137:317–322PubMedCrossRef
Metadaten
Titel
Laparoscopy-Assisted Distal Gastrectomy Versus Open Distal Gastrectomy. A Prospective Randomized Single-Blind Study
verfasst von
Shuji Takiguchi
Yoshiyuki Fujiwara
Makoto Yamasaki
Hiroshi Miyata
Kiyokazu Nakajima
Mitsugu Sekimoto
Masaki Mori
Yuichiro Doki
Publikationsdatum
01.10.2013
Verlag
Springer US
Erschienen in
World Journal of Surgery / Ausgabe 10/2013
Print ISSN: 0364-2313
Elektronische ISSN: 1432-2323
DOI
https://doi.org/10.1007/s00268-013-2121-7

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