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Erschienen in: Child's Nervous System 10/2010

01.10.2010 | Special Annual Issue

Non-invasive imaging of intracranial pediatric vascular lesions

verfasst von: Thierry A. G. M. Huisman, Samata Singhi, Pedro S. Pinto

Erschienen in: Child's Nervous System | Ausgabe 10/2010

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Abstract

Objectives

The goal of this review is to discuss the different non-invasive imaging techniques as well as the age-specific pediatric vascular pathologies and their imaging features.

Material and methods

Ultrasound, computed tomography, and magnetic resonance imaging features of pediatric ischemic stroke, intracranial hemorrhage, aneurysms, cavernomas, developmental venous anomalies, and arteriovenous malformations are presented. In addition, multiple non-invasive angiographic techniques (CT and MR angiography) and functional MRI sequences (diffusion, perfusion, and susceptibility-weighted imaging) are discussed.

Conclusion

Neurovascular imaging plays a central role in the early, sensitive, and specific diagnosis of pediatric intracranial vascular disorders. A detailed knowledge of the quality and exact angioarchitecture of pediatric vascular pathologies as well as their impact on the cerebral hemo-dynamics is essential to guide and monitor treatment options and to predict functional outcome.
Literatur
1.
Zurück zum Zitat Acciarri N, Galassi E, Giulioni M, Pozzati E, Grasso V, Palandri G, Badaloni F, Zucchelli M, Calbucci F (2009) Cavernous malformations of the central nervous system in the pediatric age group. Pediatr Neurosurg 45:81–104CrossRefPubMed Acciarri N, Galassi E, Giulioni M, Pozzati E, Grasso V, Palandri G, Badaloni F, Zucchelli M, Calbucci F (2009) Cavernous malformations of the central nervous system in the pediatric age group. Pediatr Neurosurg 45:81–104CrossRefPubMed
2.
Zurück zum Zitat Agid R, Kimchi TJ, Lee S-K, Ter Brugge KG (2007) Diagnostic characteristics and management of intracranial aneurysms in children. Neuroimaging Clin N Am 17:153–163CrossRefPubMed Agid R, Kimchi TJ, Lee S-K, Ter Brugge KG (2007) Diagnostic characteristics and management of intracranial aneurysms in children. Neuroimaging Clin N Am 17:153–163CrossRefPubMed
3.
Zurück zum Zitat Alvarez H, Monaco G, Rodesch G, Sachet M, Krings T, Lasjaunias P (2007) Vein of Galen aneurysmal malformations. Neuroimaging Clin N Am 17:189–206CrossRefPubMed Alvarez H, Monaco G, Rodesch G, Sachet M, Krings T, Lasjaunias P (2007) Vein of Galen aneurysmal malformations. Neuroimaging Clin N Am 17:189–206CrossRefPubMed
4.
Zurück zum Zitat Backens M, Schmitz B (2005) Unenhanced MR angiography. In: Schneider G, Prince MR, Meaney JFM, Ho VB (eds) Magnetic resonance angiography. Techniques, indications and practical applications. Springer, Milan, pp 3–22 Backens M, Schmitz B (2005) Unenhanced MR angiography. In: Schneider G, Prince MR, Meaney JFM, Ho VB (eds) Magnetic resonance angiography. Techniques, indications and practical applications. Springer, Milan, pp 3–22
5.
Zurück zum Zitat Batista L, Ozanne A, Barbosa M, Alvarez H, Lasjaunias P (2005) Arteriovenous malformations: diagnosis and endovascular treatment. In: Tortori-Donati P (ed) Pediatric neuroradiology: brain. Springer, Berlin, pp 287–317CrossRef Batista L, Ozanne A, Barbosa M, Alvarez H, Lasjaunias P (2005) Arteriovenous malformations: diagnosis and endovascular treatment. In: Tortori-Donati P (ed) Pediatric neuroradiology: brain. Springer, Berlin, pp 287–317CrossRef
6.
Zurück zum Zitat Chabrier S, Lasjaunias P, Husson B, Landrieu P, Tardieu M (2003) Ischemic stroke from dissection of the craniocervical arteries in childhood: report of 12 patients. Eur J Paediatr Neurol 7:39–42CrossRefPubMed Chabrier S, Lasjaunias P, Husson B, Landrieu P, Tardieu M (2003) Ischemic stroke from dissection of the craniocervical arteries in childhood: report of 12 patients. Eur J Paediatr Neurol 7:39–42CrossRefPubMed
7.
Zurück zum Zitat Da Costa L, Wallace MC, ter Brugge KG, O’Kelly C, Willinsky RA, Tymianski M (2009) The natural history and predictive features of hemorrhage from brain arteriovenous malformations. Stroke 40:100–105CrossRefPubMed Da Costa L, Wallace MC, ter Brugge KG, O’Kelly C, Willinsky RA, Tymianski M (2009) The natural history and predictive features of hemorrhage from brain arteriovenous malformations. Stroke 40:100–105CrossRefPubMed
8.
Zurück zum Zitat Daneman A, Epelman M, Blaser S, Jarrin JR (2006) Imaging of the brain in full-term neonates: does sonography still play a role? Pediatr Radiol 36:636–646CrossRefPubMed Daneman A, Epelman M, Blaser S, Jarrin JR (2006) Imaging of the brain in full-term neonates: does sonography still play a role? Pediatr Radiol 36:636–646CrossRefPubMed
9.
Zurück zum Zitat deVeber G (2002) Stroke and the child’s brain: an overview of epidemiology, syndromes and risk factors. Curr Opin Neurol 15:133–138CrossRefPubMed deVeber G (2002) Stroke and the child’s brain: an overview of epidemiology, syndromes and risk factors. Curr Opin Neurol 15:133–138CrossRefPubMed
10.
Zurück zum Zitat Garner TB, Del Curling O, Kelly DL Jr, Laster DW Jr (1991) The natural history of intracranial venous angiomas. J Neurosurg 75:715–722CrossRefPubMed Garner TB, Del Curling O, Kelly DL Jr, Laster DW Jr (1991) The natural history of intracranial venous angiomas. J Neurosurg 75:715–722CrossRefPubMed
11.
Zurück zum Zitat Hetts SW, Narvid J, Sanai N, Lawton MT, Gupta N, Fullerton HJ, Dowd CF, Higashida RT, Halbach VV (2009) Intracranial aneurysms in childhood: 27-year single-institution experience. AJNR Am J Neuroradiol 30:1315–1324CrossRefPubMed Hetts SW, Narvid J, Sanai N, Lawton MT, Gupta N, Fullerton HJ, Dowd CF, Higashida RT, Halbach VV (2009) Intracranial aneurysms in childhood: 27-year single-institution experience. AJNR Am J Neuroradiol 30:1315–1324CrossRefPubMed
12.
Zurück zum Zitat Ho VB, Corse WR, Maki JF (2005) Contrast-enhanced MR angiography: theory and technical optimization. In: Schneider G, Prince MR, Meaney JFM, Ho VB (eds) Magnetic resonance angiography. Techniques, indications and practical applications. Springer, Milan, pp 23–42 Ho VB, Corse WR, Maki JF (2005) Contrast-enhanced MR angiography: theory and technical optimization. In: Schneider G, Prince MR, Meaney JFM, Ho VB (eds) Magnetic resonance angiography. Techniques, indications and practical applications. Springer, Milan, pp 23–42
13.
Zurück zum Zitat Huisman TAGM, Wichmann W, Samara C, Valavanis A (1993) MR-angiography of cerebral cavernomas. Neuroradiology 35(Suppl):41 Huisman TAGM, Wichmann W, Samara C, Valavanis A (1993) MR-angiography of cerebral cavernomas. Neuroradiology 35(Suppl):41
14.
Zurück zum Zitat Huisman TAGM, Wichmann W, Valavanis A (1994) MRA of developmental venous anomalies (DVA). Neuroradiology 36(Suppl):143 Huisman TAGM, Wichmann W, Valavanis A (1994) MRA of developmental venous anomalies (DVA). Neuroradiology 36(Suppl):143
15.
Zurück zum Zitat Huisman TAGM (2003) Diffusion-weighted imaging: basic concepts and application in cerebral stroke and head trauma. Eur Radiol 13:2283–2297CrossRefPubMed Huisman TAGM (2003) Diffusion-weighted imaging: basic concepts and application in cerebral stroke and head trauma. Eur Radiol 13:2283–2297CrossRefPubMed
16.
Zurück zum Zitat Huisman TAGM, Sorensen AG (2004) Perfusion-weighted magnetic resonance imaging of the brain: techniques and application in children. Eur Radiol 14:59–72CrossRefPubMed Huisman TAGM, Sorensen AG (2004) Perfusion-weighted magnetic resonance imaging of the brain: techniques and application in children. Eur Radiol 14:59–72CrossRefPubMed
17.
Zurück zum Zitat Huisman TAGM (2005) Intracranial hemorrhage: ultrasound, CT and MRI findings. Eur Radiol 15:434–440CrossRefPubMed Huisman TAGM (2005) Intracranial hemorrhage: ultrasound, CT and MRI findings. Eur Radiol 15:434–440CrossRefPubMed
18.
19.
Zurück zum Zitat Kimchi TJ, Agid R, Lee S-K, Ter Brugge KG (2007) Arterial ischemic stroke in children. Neuroimaging Clin N Am 17:175–187CrossRefPubMed Kimchi TJ, Agid R, Lee S-K, Ter Brugge KG (2007) Arterial ischemic stroke in children. Neuroimaging Clin N Am 17:175–187CrossRefPubMed
20.
Zurück zum Zitat Kimchi TJ, Lee SK, Agid R, Shroff M, Ter Brugge KG (2007) Cerebral sinovenous thrombosis in children. Neuroimaging Clin N Am 17:239–244CrossRef Kimchi TJ, Lee SK, Agid R, Shroff M, Ter Brugge KG (2007) Cerebral sinovenous thrombosis in children. Neuroimaging Clin N Am 17:239–244CrossRef
21.
Zurück zum Zitat Lasjaunias PL, Campi A, Rodesch G et al (1997) Aneurysmal disease in children: review of 20 cases with intracranial locations. Interv Neuroradiol 3:215–229PubMed Lasjaunias PL, Campi A, Rodesch G et al (1997) Aneurysmal disease in children: review of 20 cases with intracranial locations. Interv Neuroradiol 3:215–229PubMed
22.
Zurück zum Zitat Lee MT, Piomelli S, Granger S, Miller ST, Brambilla DJ, Adams RJ (2006) Stroke prevention trial in sickle cell anemia (STOP): extended follow-up and final results. Blood 108:847–852CrossRefPubMed Lee MT, Piomelli S, Granger S, Miller ST, Brambilla DJ, Adams RJ (2006) Stroke prevention trial in sickle cell anemia (STOP): extended follow-up and final results. Blood 108:847–852CrossRefPubMed
23.
Zurück zum Zitat Leijser LM, de Vries LS, Cowan FM (2006) Using cerebral ultrasound effectively in the newborn infant. Early Hum Dev 82:827–835CrossRefPubMed Leijser LM, de Vries LS, Cowan FM (2006) Using cerebral ultrasound effectively in the newborn infant. Early Hum Dev 82:827–835CrossRefPubMed
24.
Zurück zum Zitat Lo WD, Lee J, Rusin J, Perkins E, Roach ES (2008) Intracranial hemorrhage in children. Arch Neurol 65:1629–1633CrossRefPubMed Lo WD, Lee J, Rusin J, Perkins E, Roach ES (2008) Intracranial hemorrhage in children. Arch Neurol 65:1629–1633CrossRefPubMed
25.
Zurück zum Zitat Lowe LH, Bulas DI (2005) Transcranial Doppler imaging in children: sickle cell screening and beyond. Pediatr Radiol 35:54–65CrossRefPubMed Lowe LH, Bulas DI (2005) Transcranial Doppler imaging in children: sickle cell screening and beyond. Pediatr Radiol 35:54–65CrossRefPubMed
26.
27.
Zurück zum Zitat McLaughlin MR, Kondziolka D, Flickinger JC, Lunsford S, Lunsford LD (1998) The prospective natural history of cerebral venous malformations. Neurosurgery 43:195–200CrossRefPubMed McLaughlin MR, Kondziolka D, Flickinger JC, Lunsford S, Lunsford LD (1998) The prospective natural history of cerebral venous malformations. Neurosurgery 43:195–200CrossRefPubMed
28.
Zurück zum Zitat Mottolese C, Hermier M, Stan H, Jouvet A, Saint-Pierre G, Froment JC, Bret P, Lapras C (2001) Central nervous system cavernomas in the pediatric age group. Neurosurg Rev 24:55–71CrossRefPubMed Mottolese C, Hermier M, Stan H, Jouvet A, Saint-Pierre G, Froment JC, Bret P, Lapras C (2001) Central nervous system cavernomas in the pediatric age group. Neurosurg Rev 24:55–71CrossRefPubMed
29.
Zurück zum Zitat Patel AN, Richaerdson AE (1971) Ruptured intracranial aneurysms in the first two decades of life: a study of 58 patients. J Neurosurg 35:571–576CrossRefPubMed Patel AN, Richaerdson AE (1971) Ruptured intracranial aneurysms in the first two decades of life: a study of 58 patients. J Neurosurg 35:571–576CrossRefPubMed
30.
Zurück zum Zitat Pereles FS, Ho VB (2005) Time-resolved MR angiography. In: Schneider G, Prince MR, Meaney JFM, Ho VB (eds) Magnetic resonance angiography. Techniques, indications and practical applications. Springer, Milan, pp 43–54 Pereles FS, Ho VB (2005) Time-resolved MR angiography. In: Schneider G, Prince MR, Meaney JFM, Ho VB (eds) Magnetic resonance angiography. Techniques, indications and practical applications. Springer, Milan, pp 43–54
31.
Zurück zum Zitat Rafay MF, Pontigon A-M, Chiang J, Adams M, Jarvis DA, Silver F, MacGregor D, deVeber GA (2009) Delay to diagnosis in acute pediatric arterial ischemic stroke. Stroke 40:58–64CrossRefPubMed Rafay MF, Pontigon A-M, Chiang J, Adams M, Jarvis DA, Silver F, MacGregor D, deVeber GA (2009) Delay to diagnosis in acute pediatric arterial ischemic stroke. Stroke 40:58–64CrossRefPubMed
32.
Zurück zum Zitat Rea D, Brandsema JF, Armstrong D, Parkin PC, deVeber G, MacGregor D, Logan WJ, Askalan R (2009) Cerebral arteriopathy in children with neurofibromatosis type 1. Pediatrics 124:e467–e483CrossRef Rea D, Brandsema JF, Armstrong D, Parkin PC, deVeber G, MacGregor D, Logan WJ, Askalan R (2009) Cerebral arteriopathy in children with neurofibromatosis type 1. Pediatrics 124:e467–e483CrossRef
33.
Zurück zum Zitat San Millan Ruiz D, Yilmaz H, Gailloud P (2009) Cerebral developmental venous anomalies: current concepts. Ann Neurol 66:271–283CrossRef San Millan Ruiz D, Yilmaz H, Gailloud P (2009) Cerebral developmental venous anomalies: current concepts. Ann Neurol 66:271–283CrossRef
34.
Zurück zum Zitat Schoenberg BS, Melinger JF, Schienberg DG (1978) Cerebrovascular disease in infants and children: a study of incidence, clinical features, and survival. Neurology 28:763–768PubMed Schoenberg BS, Melinger JF, Schienberg DG (1978) Cerebrovascular disease in infants and children: a study of incidence, clinical features, and survival. Neurology 28:763–768PubMed
35.
Zurück zum Zitat Tong KA, Ashwal S, Obenaus A, Nickerson JP, Kido D, Haacke EM (2008) Susceptibility-weighted MR imaging: a review of clinical applications in children. AJNR Am J Neuroradiol 29:9–17CrossRefPubMed Tong KA, Ashwal S, Obenaus A, Nickerson JP, Kido D, Haacke EM (2008) Susceptibility-weighted MR imaging: a review of clinical applications in children. AJNR Am J Neuroradiol 29:9–17CrossRefPubMed
36.
Zurück zum Zitat Wang J-J, Shi K-L, Li J-W, Jiang L-Q, Caspi O, Fang F, Xiao J, Jing H, Zou L-P (2009) Risk factors for arterial ischemic and hemorrhagic stroke in childhood. Pediatr Neurol 40:277–281CrossRefPubMed Wang J-J, Shi K-L, Li J-W, Jiang L-Q, Caspi O, Fang F, Xiao J, Jing H, Zou L-P (2009) Risk factors for arterial ischemic and hemorrhagic stroke in childhood. Pediatr Neurol 40:277–281CrossRefPubMed
37.
Zurück zum Zitat Zimmerman RA (2005) MRI/MRA evaluation of sickle cell disease of the brain. Pediatr Radiol 35:249–257CrossRefPubMed Zimmerman RA (2005) MRI/MRA evaluation of sickle cell disease of the brain. Pediatr Radiol 35:249–257CrossRefPubMed
38.
Zurück zum Zitat Zou Z, Ma L, Cheng L, Cai Y, Meng X (2008) Time-resolved contrast-enhanced MR angiography of intracranial lesions. J Magn Reson Imaging 27:692–699CrossRefPubMed Zou Z, Ma L, Cheng L, Cai Y, Meng X (2008) Time-resolved contrast-enhanced MR angiography of intracranial lesions. J Magn Reson Imaging 27:692–699CrossRefPubMed
Metadaten
Titel
Non-invasive imaging of intracranial pediatric vascular lesions
verfasst von
Thierry A. G. M. Huisman
Samata Singhi
Pedro S. Pinto
Publikationsdatum
01.10.2010
Verlag
Springer-Verlag
Erschienen in
Child's Nervous System / Ausgabe 10/2010
Print ISSN: 0256-7040
Elektronische ISSN: 1433-0350
DOI
https://doi.org/10.1007/s00381-010-1203-1

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