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Erschienen in: Clinical Research in Cardiology 7/2017

22.03.2017 | Review

Hypertension up to date: SPRINT to SPYRAL

verfasst von: Saarraaken Kulenthiran, Sebastian Ewen, Michael Böhm, Felix Mahfoud

Erschienen in: Clinical Research in Cardiology | Ausgabe 7/2017

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Abstract

Hypertension is the most common chronic cardiovascular condition with increasing prevalence all over the world. Treatment of patients at risk requires a multimodal therapeutic concept to adjust blood pressure, including systematic identification of secondary causes of hypertension or pseudo-resistance, lifestyle modification, polypharmacy, and as well as accompanying risk factors and comorbidities. The present review discusses recent studies on patients with increased cardiovascular risk potentially influencing future treatment strategies. It covers blood pressure targets in patients at risk (SPRINT), novel treatment options such as angiotensin receptor neprilysin inhibitors, discusses the treatment of patients with impaired glucose tolerance, and appreciates novelties in controlling therapy-resistant hypertension by fourth-line pharmacotherapies (PATHWAY), as well as new interventional approaches.
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Zurück zum Zitat Mahfoud F, Böhm M, Azizi M, Pathak A, Durand Zaleski I, Ewen S, Tsioufis K, Andersson B, Blankestijn PJ, Burnier M, Chatellier G, Gafoor S, Grassi G, Joner M, Kjeldsen SE et al (2015) Proceedings from the European clinical consensus conference for renal denervation: considerations on future clinical trial design. Eur Heart J 36(33):2219–2227. doi:10.1093/eurheartj/ehv192 CrossRefPubMed Mahfoud F, Böhm M, Azizi M, Pathak A, Durand Zaleski I, Ewen S, Tsioufis K, Andersson B, Blankestijn PJ, Burnier M, Chatellier G, Gafoor S, Grassi G, Joner M, Kjeldsen SE et al (2015) Proceedings from the European clinical consensus conference for renal denervation: considerations on future clinical trial design. Eur Heart J 36(33):2219–2227. doi:10.​1093/​eurheartj/​ehv192 CrossRefPubMed
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Zurück zum Zitat Spiering W, Van der Heyden J, Kroon AA, van der Meiracker AH, Devireddy C, Foster MT, Ghali MG, Mendelsohn FO, Reuter H, Bates MC et al (2016) Controlling and lowering blood pressure with the MobiusHD device: first-in-man interim results (CALM-FIM-Study). J Hypertens 2016(Suppl 2):e105. doi:10.1097/01.hjh.0000491608.58838.2e CrossRef Spiering W, Van der Heyden J, Kroon AA, van der Meiracker AH, Devireddy C, Foster MT, Ghali MG, Mendelsohn FO, Reuter H, Bates MC et al (2016) Controlling and lowering blood pressure with the MobiusHD device: first-in-man interim results (CALM-FIM-Study). J Hypertens 2016(Suppl 2):e105. doi:10.​1097/​01.​hjh.​0000491608.​58838.​2e CrossRef
Metadaten
Titel
Hypertension up to date: SPRINT to SPYRAL
verfasst von
Saarraaken Kulenthiran
Sebastian Ewen
Michael Böhm
Felix Mahfoud
Publikationsdatum
22.03.2017
Verlag
Springer Berlin Heidelberg
Erschienen in
Clinical Research in Cardiology / Ausgabe 7/2017
Print ISSN: 1861-0684
Elektronische ISSN: 1861-0692
DOI
https://doi.org/10.1007/s00392-017-1095-0

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