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Clinical Research in Cardiology

Clinical Research in Cardiology OnlineFirst articles

04.01.2019 | Original Paper Open Access

Prognostic significance of changes in heart rate following uptitration of beta-blockers in patients with sub-optimally treated heart failure with reduced ejection fraction in sinus rhythm versus atrial fibrillation

Heart rate is a risk factor in patients with heart failure with reduced ejection fraction (HFrEF) that, when reduced, provides outcome benefits [ 1 , 2 ]. However, the benefit of heart rate-mediated reduction is less clear in atrial fibrillation …

03.01.2019 | Original Paper

Incidence, predictors, and outcomes of DAPT disruption due to non-compliance vs. bleeding after PCI: insights from the PARIS Registry

The World Health Organization (WHO) reports that approximately 50% of patients do not take medications as prescribed, and that anywhere from one-third to two-third of hospitalizations are due to poor medication adherence, even in developed …

02.01.2019 | Original Paper

Direct oral anticoagulants and vitamin K antagonists are linked to differential profiles of cardiac function and lipid metabolism

Anticoagulation therapy with vitamin K antagonist (VKA) has represented one of the cornerstones of antithrombotic therapy for decades [ 1 ]. The introduction of direct acting oral anticoagulants (DOAC) has considerably changed the landscape and …

02.01.2019 | Original Paper

Impact of eplerenone on major cardiovascular outcomes in patients with systolic heart failure according to baseline heart rate

Elevated resting heart rate is an established risk factor for cardiovascular mortality and morbidity in people with cardiovascular disease [ 1 ]. The magnitude of autonomic dysfunction is partly reflected by heart rate [ 2 ], and increased heart …

21.12.2018 | Original Paper

Prognostic impact of chronic kidney disease and renal replacement therapy in ventricular tachyarrhythmias and aborted cardiac arrest

Compared to the general population, patients suffering from chronic kidney disease (CKD) are associated with a higher incidence of arterial wall thickening and stiffness leading to progressive coronary calcification [ 1 – 3 ]. This CKD-related …

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International journal for clinical cardiovascular research. It provides a forum for original and review articles as well as clinical correspondence and critical perspective articles. Articles are only accepted if they meet stringent scientific standards and have undergone peer review. The journal regularly receives articles from the field of clinical cardiology, angiology, as well as heart and vascular surgery. As the official journal of the German Cardiac Society, it gives a current and competent survey on the diagnosis and therapy of heart and vascular diseases. Supplemental issues are published in Clinical Research of Cardiology Supplements.


  •  Deutsche Gesellschaft für Kardiologie - Herz- und Kreislaufforschung e.V. (DGK)
  •  Deutsche Gesellschaft für Pädiatrische Kardiologie (DGPK)
  •  Deutsche Gesellschaft für Prävention und Rehabilitation von Herz-Kreislauf-Erkrankungen 
  • Arbeitsgemeinschaft Leitender Kardiologischer Krankenhausärzte (ALKK)
  • Sektion Kardiologie im BDI
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