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01.04.2015 | Original Paper

Regulation of lipid production by light-emitting diodes in human sebocytes

verfasst von: Yu Ra Jung, Sue Jeong Kim, Kyung Cheol Sohn, Young Lee, Young Joon Seo, Young Ho Lee, Kyu Uang Whang, Chang Deok Kim, Jeung Hoon Lee, Myung Im

Erschienen in: Archives of Dermatological Research | Ausgabe 3/2015

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Abstract

Light-emitting diodes (LED) have been used to treat acne vulgaris. However, the efficacy of LED on sebaceous lipid production in vitro has not been examined. This study investigated the efficacy of 415 nm blue light and 630 nm red light on lipid production in human sebocytes. When applied to human primary sebocytes, 415 nm blue light suppressed cell proliferation. Based on a lipogenesis study using Oil Red O, Nile red staining, and thin-layered chromatography, 630 nm red light strongly downregulated lipid production in sebocytes. These results suggest that 415 nm blue light and 630 nm red light influence lipid production in human sebocytes and have beneficial effects on acne by suppressing sebum production.

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Titel: Regulation of lipid production by light-emitting diodes in human sebocytes
verfasst von: Yu Ra Jung
Sue Jeong Kim
Kyung Cheol Sohn
Young Lee
Young Joon Seo
Young Ho Lee
Kyu Uang Whang
Chang Deok Kim
Jeung Hoon Lee
Myung Im
Publikationsdatum: 01.04.2015
Verlag: Springer Berlin Heidelberg
Erschienen in: Archives of Dermatological Research / Ausgabe 3/2015
Print ISSN: 0340-3696
Elektronische ISSN: 1432-069X
DOI: https://doi.org/10.1007/s00403-015-1547-1

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Regulation of lipid production by light-emitting diodes in human sebocytes

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