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01.02.2009 | Original Article

Acute kidney injury requiring dialysis in obstetric patients: a series of 55 cases in Brazil

verfasst von: Geraldo B. Silva Jr, Francisco Amaury Monteiro, Rosa M. S. Mota, José Gerardo A. Paiva, José Walter Correia, José G. Bezerra Filho, Rafael N. Macedo, Rafael S. A. Lima, Elizabeth F. Daher

Erschienen in: Archives of Gynecology and Obstetrics | Ausgabe 2/2009

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Abstract

Objective

To investigate the risk factors associated with oliguria and death in obstetric patients with acute kidney injury (AKI).

Methods

The study group included all obstetric patients with AKI, under dialytic treatment, in Hospital Geral César Cals, Fortaleza, Brazil, from January 2000 to December 2006. AKI were classified according to the RIFLE criteria. Univariate and multivariate analysis were performed to investigate the factors associated with oliguria and death.

Results

A total of 55 patients were included. Their average age was 26.2 ± 6.7 years. The main etiologies of AKI were pregnancy-related hypertension (41.8%), HELLP syndrome (40%), puerperal sepsis (14.5%), abruption placentae (9.1%), hemolytic uremic syndrome (9.1%) and thrombotic thrombocytopenic purpura (5.5%). Oliguria was observed in 36 cases (65%). Death occurred in 17 cases (30.9%). Factors associated with oliguria were, diagnosis of HELLP syndrome, hyperbilirubinemia and death. Factors associated with death were, presence of puerperal sepsis, hyperbilirubinemia, hypotension, oliguria and low levels of HCO₃.

Conclusion

AKI is a rare but potential fatal complication in obstetric patients. RIFLE criteria seem to have association with mortality. There are important factors associated with oliguria and death, which must be prompt recognized to the institution of adequate therapeutic measures.

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Titel: Acute kidney injury requiring dialysis in obstetric patients: a series of 55 cases in Brazil
verfasst von: Geraldo B. Silva Jr
Francisco Amaury Monteiro
Rosa M. S. Mota
José Gerardo A. Paiva
José Walter Correia
José G. Bezerra Filho
Rafael N. Macedo
Rafael S. A. Lima
Elizabeth F. Daher
Publikationsdatum: 01.02.2009
Verlag: Springer-Verlag
Erschienen in: Archives of Gynecology and Obstetrics / Ausgabe 2/2009
Print ISSN: 0932-0067
Elektronische ISSN: 1432-0711
DOI: https://doi.org/10.1007/s00404-008-0682-8

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