Skip to main content
Erschienen in: Archives of Gynecology and Obstetrics 2/2009

01.02.2009 | Original Article

Primary care sector versus treatment centre follow up for post-treatment cervical squamous intraepithelial neoplasia (SIL)

verfasst von: Piya Ray, Kavitha Madhuri Thumuluru, Veena Kaul

Erschienen in: Archives of Gynecology and Obstetrics | Ausgabe 2/2009

Einloggen, um Zugang zu erhalten

Abstract

Objective

The NHSCSP 2004 guideline recommends that the best practice for the follow up of post-treatment squamous intraepithelial neoplasia (SIL) is by cytological surveillance in the treatment centre or alternatively, in the primary care sector as a minimum standard. We undertook this study to test this recommendation.

Setting

In a colposcopy clinic of a district general hospital of UK.

Population

Retrospective analysis of 418 patients treated for squamous intraepithelial neoplasia whose post treatment cytological surveillance was followed up for 18 months after treatment. A prospective patient preference questionnaire was also undertaken in 50 randomly chosen patients having treatment to elicit their preferences for the place of follow up.

Results

At 8 months 66.4% had their first smear in the primary care sector as compared to 88.6% in the treatment centre. The post-treatment follow up smear performance graph seems to be different for the primary care sector compared to treatment centre. In 12 months nearly 90% of the patients had at least one smear and by 18 months 96.9% of the treated patients had a follow up smear in the community which would detect residual disease. There was no statistically significant difference in the detection of residual disease in the community compared to the treatment centre during the follow up period. A total of 76% of patients preferred to have their follow up smears in the primary care.

Conclusion

Targets set by the NHSCSP of UK were not met either by the primary care sector or the treatment centre in the 8 months but was satisfactorily achieved by both in 12 months.

Recommendation

These preliminary results indicate a need for a larger multi centre randomised trial to establish if the primary sector is truly a satisfactory alternative for patient follow up. Cytological surveillance is best carried out in the place desired by the patients to allow good compliance with the monitoring process.
Literatur
1.
Zurück zum Zitat Soutter WP, Lopes A, Fletcher A et al (1997) Invasive cancer after conservative therapy for CIN. Lancet 349:978–980PubMedCrossRef Soutter WP, Lopes A, Fletcher A et al (1997) Invasive cancer after conservative therapy for CIN. Lancet 349:978–980PubMedCrossRef
2.
Zurück zum Zitat Giles J et al (1989) Medical audit in the followup of patients treated for cervical intraepithelial neoplasia. J Obstet Gynecol 10:78–79 Giles J et al (1989) Medical audit in the followup of patients treated for cervical intraepithelial neoplasia. J Obstet Gynecol 10:78–79
3.
Zurück zum Zitat Mcindoe WA et al (1984) The invasive potential of carcinoma in situ of the cervix. Am J Obstet Gynecol 64:451–458 Mcindoe WA et al (1984) The invasive potential of carcinoma in situ of the cervix. Am J Obstet Gynecol 64:451–458
4.
Zurück zum Zitat Grunsell H, Alm P, Larsson G (1983) Cure rates after laser conisation for early cervical neoplasia. Ann Chir Gynaecol 72:218–222 Grunsell H, Alm P, Larsson G (1983) Cure rates after laser conisation for early cervical neoplasia. Ann Chir Gynaecol 72:218–222
5.
Zurück zum Zitat Anderson ES, Nielson K, Larsen G (1990) Laser conisation:followup in patients with cervical intraepithelial neoplasia in the cone margin. Gynecol Oncol 39:328–331CrossRef Anderson ES, Nielson K, Larsen G (1990) Laser conisation:followup in patients with cervical intraepithelial neoplasia in the cone margin. Gynecol Oncol 39:328–331CrossRef
6.
Zurück zum Zitat Biggrig A, Haffenden DK, Sheehan AL, Codling BW, Read MD (1994) Efficacy and safety of large loop excision of the transformation zone. Lancet 343:32–34CrossRef Biggrig A, Haffenden DK, Sheehan AL, Codling BW, Read MD (1994) Efficacy and safety of large loop excision of the transformation zone. Lancet 343:32–34CrossRef
7.
Zurück zum Zitat Soutter WP, Butler JS, Tipples M (2006) The role of colposcopy in the followup of women treated for cervical intraepithelial neoplasia. BJOG May 113(5):511–514CrossRef Soutter WP, Butler JS, Tipples M (2006) The role of colposcopy in the followup of women treated for cervical intraepithelial neoplasia. BJOG May 113(5):511–514CrossRef
8.
Zurück zum Zitat Paraskevaidis E, Jandial L, Mann EM, Fisher PM, Kitchener HC (1991) Pattern of treatment failure following laser for cervical intraepithelial neoplasia: implications for follow-up protocol. Obstet Gynecol 78(1):80–83PubMed Paraskevaidis E, Jandial L, Mann EM, Fisher PM, Kitchener HC (1991) Pattern of treatment failure following laser for cervical intraepithelial neoplasia: implications for follow-up protocol. Obstet Gynecol 78(1):80–83PubMed
Metadaten
Titel
Primary care sector versus treatment centre follow up for post-treatment cervical squamous intraepithelial neoplasia (SIL)
verfasst von
Piya Ray
Kavitha Madhuri Thumuluru
Veena Kaul
Publikationsdatum
01.02.2009
Verlag
Springer-Verlag
Erschienen in
Archives of Gynecology and Obstetrics / Ausgabe 2/2009
Print ISSN: 0932-0067
Elektronische ISSN: 1432-0711
DOI
https://doi.org/10.1007/s00404-008-0674-8

Weitere Artikel der Ausgabe 2/2009

Archives of Gynecology and Obstetrics 2/2009 Zur Ausgabe

Blutdrucksenkung könnte Uterusmyome verhindern

Frauen mit unbehandelter oder neu auftretender Hypertonie haben ein deutlich erhöhtes Risiko für Uterusmyome. Eine Therapie mit Antihypertensiva geht hingegen mit einer verringerten Inzidenz der gutartigen Tumoren einher.

Antikörper-Wirkstoff-Konjugat hält solide Tumoren in Schach

16.05.2024 Zielgerichtete Therapie Nachrichten

Trastuzumab deruxtecan scheint auch jenseits von Lungenkrebs gut gegen solide Tumoren mit HER2-Mutationen zu wirken. Dafür sprechen die Daten einer offenen Pan-Tumor-Studie.

Mammakarzinom: Senken Statine das krebsbedingte Sterberisiko?

15.05.2024 Mammakarzinom Nachrichten

Frauen mit lokalem oder metastasiertem Brustkrebs, die Statine einnehmen, haben eine niedrigere krebsspezifische Mortalität als Patientinnen, die dies nicht tun, legen neue Daten aus den USA nahe.

S3-Leitlinie zur unkomplizierten Zystitis: Auf Antibiotika verzichten?

15.05.2024 Harnwegsinfektionen Nachrichten

Welche Antibiotika darf man bei unkomplizierter Zystitis verwenden und wovon sollte man die Finger lassen? Welche pflanzlichen Präparate können helfen? Was taugt der zugelassene Impfstoff? Antworten vom Koordinator der frisch überarbeiteten S3-Leitlinie, Prof. Florian Wagenlehner.

Update Gynäkologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert – ganz bequem per eMail.