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Medical Microbiology and Immunology

Erschienen in:

19.01.2018 | Review

The microbiology and treatment of human mastitis

verfasst von: Angeliki Angelopoulou, Des Field, C. Anthony Ryan, Catherine Stanton, Colin Hill, R. Paul Ross

Erschienen in: Medical Microbiology and Immunology | Ausgabe 2/2018

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Abstract

Mastitis, which is generally described as an inflammation of breast tissue, is a common and debilitating disease which frequently results in the cessation of exclusive breastfeeding and affects up to 33% of lactating women. The condition is a primary cause of decreased milk production and results in organoleptic and nutritional alterations in milk quality. Recent studies employing culture-independent techniques, including metagenomic sequencing, have revealed a loss of bacterial diversity in the microbiome of mastitic milk samples compared to healthy milk samples. In those infected, the pathogens Staphylococcus aureus, Staphylococcus epidermidis and members of corynebacteria have been identified as the predominant etiological agents in acute, subacute and granulomatous mastitis, respectively. The increased incidence of antibiotic resistance in the causative species is also a key cause of concern for treatment of the disease, thus leading to the need to develop novel therapies. In this respect, probiotics and bacteriocins have revealed potential as alternative treatments.

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Titel: The microbiology and treatment of human mastitis
verfasst von: Angeliki Angelopoulou
Des Field
C. Anthony Ryan
Catherine Stanton
Colin Hill
R. Paul Ross
Publikationsdatum: 19.01.2018
Verlag: Springer Berlin Heidelberg
Erschienen in: Medical Microbiology and Immunology / Ausgabe 2/2018
Print ISSN: 0300-8584
Elektronische ISSN: 1432-1831
DOI: https://doi.org/10.1007/s00430-017-0532-z

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25.04.2024 | Hypotonie | Nachrichten

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