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Medical Microbiology and Immunology

Medical Microbiology and Immunology OnlineFirst articles

12.09.2018 | Original Investigation

Intranasal co-administration of recombinant active fragment of Zonula occludens toxin and truncated recombinant EspB triggers potent systemic, mucosal immune responses and reduces span of E. coli O157:H7 fecal shedding in BALB/c mice

Escherichia coli O157:H7 with its traits such as intestinal colonization and fecal-oral route of transmission demands mucosal vaccine development. E. coli secreted protein B (EspB) is one of the key type III secretory system (TTSS) targets for …

10.09.2018 | Original Investigation

Role of pentamer complex-specific and IgG subclass 3 antibodies in HCMV hyperimmunoglobulin and standard intravenous IgG preparations

HCMV is a ubiquitous virus that causes an incidence of congenital infection in the range of 0.2–2% of all live births. After a primary maternal infection during pregnancy maternal–fetal transmission rates increase from 9% in early or …

10.09.2018 | Original Investigation

The sequence analysis of Epstein–Barr virus EBNA1 gene: could viral screening markers for nasopharyngeal carcinoma be identified?

Epstein–Barr virus (EBV) has been identified as a group 1 carcinogenic agent, particularly for nasopharyngeal carcinoma (NPC). The sequence diversity of EBV nuclear antigen 1 (EBNA1) reflects region-restricted polymorphisms, which may be …

31.08.2018 | Original Investigation

Activation of brain endothelium by Escherichia coli K1 virulence factor cglD promotes polymorphonuclear leukocyte transendothelial migration

Escherichia coli K1 is the most common Gram-negative bacteria causing neonatal meningitis. Polymorphonuclear leukocyte (PMN) transmigration across the blood–brain barrier (BBB) is the hallmark of bacterial meningitis. Reportedly, the deletion of …

30.08.2018 | Original Investigation

Polymorphisms in the TGFB1 signal peptide influence human papillomavirus infection and development of cervical lesions

The main purpose was to assess the effect of c.29C>T and c.74G>C polymorphisms in the TGFB1 signal peptide on HPV infection and development of cervical lesions. Cervical swabs and blood samples were obtained from 349 outpatient women, along with …

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Medical Microbiology and Immunology covers all aspects of the interrelationship between infectious agents and their hosts. Among the major topics covered are microbial and viral pathogenesis and the immunological host response to infections. The journal also publishes information from other fields of microbiology, including mycology and parasitology.

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