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European Journal of Pediatrics

Erschienen in:

30.05.2020 | COVID-19 | Review Zur Zeit gratis

Children’s heart and COVID-19: Up-to-date evidence in the form of a systematic review

verfasst von: Giulia Sanna, Gaia Serrau, Pier Paolo Bassareo, Paola Neroni, Vassilios Fanos, Maria Antonietta Marcialis

Erschienen in: European Journal of Pediatrics | Ausgabe 7/2020

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Abstract

The new coronavirus disease outbreak in 2019 (COVID-19) represents a dramatic challenge for healthcare systems worldwide. As to viral tropism, lungs are not the only COVID-19 target but also the heart may be involved in a not negligible percentage of the infected patients. Myocarditis-related cardiac dysfunction and potentially life-threatening arrhythmias are the main aftermaths. A few studies showed that myocardial injury in adult patients is often linked with a fatal outcome. Conversely, scientific evidence in children is sparse, although several reports were published with the description of a cardiac involvement in COVID-19 paediatric patients. In these young subjects, a background of surgically treated congenital heart disease seems to be a predisposing factor.

Conclusion: This systematic review is aimed at summarizing all COVID-19 cases with a cardiac involvement published in paediatric age and trying to explain the underlying mechanisms responsible for COVID-19-related myocardial damage.

What is Known: • Coronaviruses proved to be able to jump from animals to humans. • The outbreak of COVID-19 started from China (Dec 2019) and became pandemic.
What is New: • Even in childhood, COVID-19 is not without the risk of cardiac involvement. • Myocarditis, heart failure, and arrhythmias are among the possible manifestations.

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Titel: Children’s heart and COVID-19: Up-to-date evidence in the form of a systematic review
verfasst von: Giulia Sanna
Gaia Serrau
Pier Paolo Bassareo
Paola Neroni
Vassilios Fanos
Maria Antonietta Marcialis
Publikationsdatum: 30.05.2020
Verlag: Springer Berlin Heidelberg
Schlagwort: COVID-19
Erschienen in: European Journal of Pediatrics / Ausgabe 7/2020
Print ISSN: 0340-6199
Elektronische ISSN: 1432-1076
DOI: https://doi.org/10.1007/s00431-020-03699-0

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Children’s heart and COVID-19: Up-to-date evidence in the form of a systematic review

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