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Journal of Neural Transmission
Erschienen in: Journal of Neural Transmission 11/2013

01.11.2013 | Neurology and Preclinical Neurological Studies - Review Article

Movement disorders in systemic lupus erythematosus and the antiphospholipid syndrome

verfasst von: José Fidel Baizabal-Carvallo, Cecilia Bonnet, Joseph Jankovic

Erschienen in: Journal of Neural Transmission | Ausgabe 11/2013

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Abstract

Movement disorders (MDs), particularly chorea, may be the presenting neurological complication of systemic lupus erythematosus (SLE) and the antiphospholipid syndrome (APS), but the association is not often initially recognized. Current evidence suggests an autoimmune mechanism related to antiphospholipid antibodies in these two conditions, although the antigenic target within the central nervous system has not yet been identified. Based on a comprehensive review of the literature, this article summarizes the current knowledge on MDs in SLE and APS. A high index of suspicion is required to make an early diagnosis and initiate appropriate treatment to provide symptomatic relief and to prevent other systemic complications related to the autoimmune process.
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Metadaten
Titel
Movement disorders in systemic lupus erythematosus and the antiphospholipid syndrome
verfasst von
José Fidel Baizabal-Carvallo
Cecilia Bonnet
Joseph Jankovic
Publikationsdatum
01.11.2013
Verlag
Springer Vienna
Erschienen in
Journal of Neural Transmission / Ausgabe 11/2013
Print ISSN: 0300-9564
Elektronische ISSN: 1435-1463
DOI
https://doi.org/10.1007/s00702-013-1023-z

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