Skip to main content
Erschienen in: Journal of Bone and Mineral Metabolism 1/2016

01.01.2016 | Original Article

Mortality after hip fracture with vertebral compression fracture is poor

verfasst von: Norio Imai, Naoto Endo, Tadashi Hoshino, Ken Suda, Dai Miyasaka, Tomoyuki Ito

Erschienen in: Journal of Bone and Mineral Metabolism | Ausgabe 1/2016

Einloggen, um Zugang zu erhalten

Abstract

Due to the increasing elderly population, the prevalence of osteoporotic hip fractures in Japanese patients continues to rise. It is well established that patients with either hip fracture or both symptomatic and asymptomatic morphometric vertebral compression fracture (VCF) have a poor health prognosis compared with the general population. The purpose of this study was to retrospectively investigate vertebral fracture rates among patients with hip fracture and their influence on mortality. We examined 182 cases of osteoporotic hip fracture in patients admitted to our institution between January 2009 and May 2011. The average age at the time of fracture was 85 years. Radiographs of the lumbar spine were obtained from all of the participants and the lateral spinal radiographs were examined for evidence of VCF. The patients were classified into two groups, those with VCF and those without. A VCF was identified in approximately 78 % of the patients. The mortality rate 1 year after the hip fracture was approximately 22 % and it was significantly higher in patients with VCF. Through multivariate statistics we found that VCF, post-operative complication, loss of ambulation after operation and medication for osteoporosis were statistically significant. In other words, VCF, post-operative complication and loss of ambulation were considered to be poor prognostic factors and medication for osteoporosis was likely to improve the prognosis. We concluded that the risk of mortality after hip fracture is significantly greater in patients who also have VCF compared to patients without VCF, and that medication for osteoporosis is likely to improve prognosis.
Literatur
1.
Zurück zum Zitat Morita Y, Endo N, Iga T, Kunihiko T, Ohkawa Y (2002) The incidence of cervical and trochanteric fractures of the proximal femur in 1999 in Niigata Prefecture, Japan. J Bone Miner Metab 20:311–318PubMedCrossRef Morita Y, Endo N, Iga T, Kunihiko T, Ohkawa Y (2002) The incidence of cervical and trochanteric fractures of the proximal femur in 1999 in Niigata Prefecture, Japan. J Bone Miner Metab 20:311–318PubMedCrossRef
2.
Zurück zum Zitat Orimo H, Yaegashi Y, Onoda T, Yasumasa F, Hosoi T, Sakata K (2009) Hip fracture incidence in Japan: estimates of new patients in 2007 and 20-year trends. Arch Osteoporos 4:71–77PubMedPubMedCentralCrossRef Orimo H, Yaegashi Y, Onoda T, Yasumasa F, Hosoi T, Sakata K (2009) Hip fracture incidence in Japan: estimates of new patients in 2007 and 20-year trends. Arch Osteoporos 4:71–77PubMedPubMedCentralCrossRef
3.
Zurück zum Zitat Hagino H, Furukawa K, Fujiwara S, Okano T, Katagiri H, Yamamoto K, Teshima R (2009) Recent trends in the incidence and lifetime risk of hip fracture in Tottori, Japan. Osteoporos Int 20:543–548PubMedCrossRef Hagino H, Furukawa K, Fujiwara S, Okano T, Katagiri H, Yamamoto K, Teshima R (2009) Recent trends in the incidence and lifetime risk of hip fracture in Tottori, Japan. Osteoporos Int 20:543–548PubMedCrossRef
4.
Zurück zum Zitat Chevally T, Guilley E, Herrmann FR, Hoffmeyer P, Rapin CH, Rizzoli R (2007) Incidence of hip fracture over a 10-year period (1991–2000): reversal of a secular trend. Bone 40:1284–1289CrossRef Chevally T, Guilley E, Herrmann FR, Hoffmeyer P, Rapin CH, Rizzoli R (2007) Incidence of hip fracture over a 10-year period (1991–2000): reversal of a secular trend. Bone 40:1284–1289CrossRef
5.
6.
Zurück zum Zitat Kannus P, Niemi S, Parkkari J, Palvanen M, Vuori I, Järivinen M (2006) Nationwide decline in incidence of hip fracture. J Bone Miner Res 21:1836–1838PubMedCrossRef Kannus P, Niemi S, Parkkari J, Palvanen M, Vuori I, Järivinen M (2006) Nationwide decline in incidence of hip fracture. J Bone Miner Res 21:1836–1838PubMedCrossRef
7.
Zurück zum Zitat Johnell O, Kanis JA, Odén A, Sernbo L, Redlund-Johnell C, Petterson C, Laet C, Jönsson B (2004) Mortality after osteoporotic fractures. Osteoporos Int 15:38–42PubMedCrossRef Johnell O, Kanis JA, Odén A, Sernbo L, Redlund-Johnell C, Petterson C, Laet C, Jönsson B (2004) Mortality after osteoporotic fractures. Osteoporos Int 15:38–42PubMedCrossRef
8.
Zurück zum Zitat Bliuc D, Nguyen D, Milch VE, Nguyen TV, Eisman JA, Center JR (2009) Mortality risk associated with low-trauma osteoporotic fracture and subsequent fracture in men and women. JAMA 301:513–521PubMedCrossRef Bliuc D, Nguyen D, Milch VE, Nguyen TV, Eisman JA, Center JR (2009) Mortality risk associated with low-trauma osteoporotic fracture and subsequent fracture in men and women. JAMA 301:513–521PubMedCrossRef
9.
Zurück zum Zitat Ioannidis G, Papaioannou A, Hopman WN, Akhtar-Danesh N, Anastassiades T, Pickard L, Kennedy CC, Prior JC, Olszynski WP, Davison KS, Goltzman D, Thabane L, Gafni A, Papadimitropoulos EA, Brown JP, Josse RG, Hanley DA, Adachi JD (2009) Relation between fractures and mortality: results from the Canadian multicentre osteoporosis study. CMAJ 181:265–271PubMedPubMedCentralCrossRef Ioannidis G, Papaioannou A, Hopman WN, Akhtar-Danesh N, Anastassiades T, Pickard L, Kennedy CC, Prior JC, Olszynski WP, Davison KS, Goltzman D, Thabane L, Gafni A, Papadimitropoulos EA, Brown JP, Josse RG, Hanley DA, Adachi JD (2009) Relation between fractures and mortality: results from the Canadian multicentre osteoporosis study. CMAJ 181:265–271PubMedPubMedCentralCrossRef
10.
Zurück zum Zitat Orimo H, Hayashi Y, Fukunaga M, Sone T, Fujiwara S, Shiraki M, Kushida K, Miyamoto S, Soen S, Nishimura J, Ohashi Y, Hosoi T, Gomi I, Takana H, Ikai T, Kishimoto H (2001) Gempatsusei kotusosyousyou no sindan kijun 2000 nendo kaitei ban. Nihon Kotsutaisya Gakkai Zasshi 14:76–82 (in Japanese) Orimo H, Hayashi Y, Fukunaga M, Sone T, Fujiwara S, Shiraki M, Kushida K, Miyamoto S, Soen S, Nishimura J, Ohashi Y, Hosoi T, Gomi I, Takana H, Ikai T, Kishimoto H (2001) Gempatsusei kotusosyousyou no sindan kijun 2000 nendo kaitei ban. Nihon Kotsutaisya Gakkai Zasshi 14:76–82 (in Japanese)
11.
Zurück zum Zitat Chirodian N, Arch B, Parker MJ (2005) Sliding hip screw fixation of trochanteric hip fractures: outcome of 1024 procedures. Injury 36:793–800PubMedCrossRef Chirodian N, Arch B, Parker MJ (2005) Sliding hip screw fixation of trochanteric hip fractures: outcome of 1024 procedures. Injury 36:793–800PubMedCrossRef
12.
Zurück zum Zitat McLeod K, Brodie MP, Fahey PP, Gray RA (2005) Long-term survival of surgically treated hip fracture in an Australian regional hospital. Anaesth Intensive Care 33:749–755PubMed McLeod K, Brodie MP, Fahey PP, Gray RA (2005) Long-term survival of surgically treated hip fracture in an Australian regional hospital. Anaesth Intensive Care 33:749–755PubMed
13.
Zurück zum Zitat Petersen MB, Jørgensen HL, Hansen K, Duus BR (2006) Factors affecting post-operative mortality of patients with displaced femoral neck fracture. Injury 37:705–711PubMedCrossRef Petersen MB, Jørgensen HL, Hansen K, Duus BR (2006) Factors affecting post-operative mortality of patients with displaced femoral neck fracture. Injury 37:705–711PubMedCrossRef
14.
Zurück zum Zitat Alarcón T, González-Montalvo JI, Bárcena A, Saez P (2001) Further experience of nonagenarians with hip fractures. Injury 32:555–558PubMedCrossRef Alarcón T, González-Montalvo JI, Bárcena A, Saez P (2001) Further experience of nonagenarians with hip fractures. Injury 32:555–558PubMedCrossRef
15.
Zurück zum Zitat Sakamoto K, Nakamura T, Hagino H, Endo N, Mori S, Muto Y, Harad A, Yamamoto S, Tomita K, Yoshimura M, Yamamoto H (2006) Report on the Japanese Orthopaedic Association’s 3-year project observing hip fractures at fixed-point hospitals. J Orthop Sci 11:127–134PubMedCrossRef Sakamoto K, Nakamura T, Hagino H, Endo N, Mori S, Muto Y, Harad A, Yamamoto S, Tomita K, Yoshimura M, Yamamoto H (2006) Report on the Japanese Orthopaedic Association’s 3-year project observing hip fractures at fixed-point hospitals. J Orthop Sci 11:127–134PubMedCrossRef
16.
Zurück zum Zitat Lau E, Ong K, Kurtz S, Schmier J, Edidin A (2008) Mortality following the diagnosis of vertebral compression fracture in the Medicare population. J Bone Joint Surg 90:1479–1486PubMedCrossRef Lau E, Ong K, Kurtz S, Schmier J, Edidin A (2008) Mortality following the diagnosis of vertebral compression fracture in the Medicare population. J Bone Joint Surg 90:1479–1486PubMedCrossRef
17.
Zurück zum Zitat Sakuma M, Endo N, Oinuma T, Endo E, Yazawa T, Watanabe K, Watanabe S (2008) Incidence and outcome of osteoporotic fractures in 2004 in Sado City, Niigata Prefecture, Japan. J Bone Miner Metab 26:373–378PubMedCrossRef Sakuma M, Endo N, Oinuma T, Endo E, Yazawa T, Watanabe K, Watanabe S (2008) Incidence and outcome of osteoporotic fractures in 2004 in Sado City, Niigata Prefecture, Japan. J Bone Miner Metab 26:373–378PubMedCrossRef
18.
Zurück zum Zitat Boonen S, Lips P, Bouillon R, Bischoff-Ferrari A, Vanderschueren D, Haentjens P (2007) Need for additional calcium to reduce the risk of hip fracture with vitamin D supplementation: evidence from a comparative metaanalysis of randomized controlled trials. J Clin Endocrinol Metab 92:1415–1423PubMedCrossRef Boonen S, Lips P, Bouillon R, Bischoff-Ferrari A, Vanderschueren D, Haentjens P (2007) Need for additional calcium to reduce the risk of hip fracture with vitamin D supplementation: evidence from a comparative metaanalysis of randomized controlled trials. J Clin Endocrinol Metab 92:1415–1423PubMedCrossRef
19.
Zurück zum Zitat Papapoulos SE, Quandt SA, Liberman UA, Hochberg MC, Thompson DE (2005) Meta-analysis of the efficacy of alendronate for the prevention of hip fractures in postmenopausal women. Osteoporos Int 16:468–474PubMedCrossRef Papapoulos SE, Quandt SA, Liberman UA, Hochberg MC, Thompson DE (2005) Meta-analysis of the efficacy of alendronate for the prevention of hip fractures in postmenopausal women. Osteoporos Int 16:468–474PubMedCrossRef
20.
Zurück zum Zitat Lyles KW, Colón-Emeric CS, Magaziner JS, Adachi JD, Pieper CF, Mautalen C, Hyldstrup L, Recknor C, Nordsletten L, Moore KA, Lavecchia C, Zhang J, Mesenbrink P, Hodgson PK, Abrams K, Orloff JJ, Horowitz Z, Eriksen EF, Boonen S (2007) Zoledronic acid and clinical fractures and mortality after hip fracture. N Engl J Med 357:1799–1809PubMedCrossRef Lyles KW, Colón-Emeric CS, Magaziner JS, Adachi JD, Pieper CF, Mautalen C, Hyldstrup L, Recknor C, Nordsletten L, Moore KA, Lavecchia C, Zhang J, Mesenbrink P, Hodgson PK, Abrams K, Orloff JJ, Horowitz Z, Eriksen EF, Boonen S (2007) Zoledronic acid and clinical fractures and mortality after hip fracture. N Engl J Med 357:1799–1809PubMedCrossRef
Metadaten
Titel
Mortality after hip fracture with vertebral compression fracture is poor
verfasst von
Norio Imai
Naoto Endo
Tadashi Hoshino
Ken Suda
Dai Miyasaka
Tomoyuki Ito
Publikationsdatum
01.01.2016
Verlag
Springer Japan
Erschienen in
Journal of Bone and Mineral Metabolism / Ausgabe 1/2016
Print ISSN: 0914-8779
Elektronische ISSN: 1435-5604
DOI
https://doi.org/10.1007/s00774-014-0640-4

Weitere Artikel der Ausgabe 1/2016

Journal of Bone and Mineral Metabolism 1/2016 Zur Ausgabe

Leitlinien kompakt für die Innere Medizin

Mit medbee Pocketcards sicher entscheiden.

Seit 2022 gehört die medbee GmbH zum Springer Medizin Verlag

Notfall-TEP der Hüfte ist auch bei 90-Jährigen machbar

26.04.2024 Hüft-TEP Nachrichten

Ob bei einer Notfalloperation nach Schenkelhalsfraktur eine Hemiarthroplastik oder eine totale Endoprothese (TEP) eingebaut wird, sollte nicht allein vom Alter der Patientinnen und Patienten abhängen. Auch über 90-Jährige können von der TEP profitieren.

Niedriger diastolischer Blutdruck erhöht Risiko für schwere kardiovaskuläre Komplikationen

25.04.2024 Hypotonie Nachrichten

Wenn unter einer medikamentösen Hochdrucktherapie der diastolische Blutdruck in den Keller geht, steigt das Risiko für schwere kardiovaskuläre Ereignisse: Darauf deutet eine Sekundäranalyse der SPRINT-Studie hin.

Bei schweren Reaktionen auf Insektenstiche empfiehlt sich eine spezifische Immuntherapie

Insektenstiche sind bei Erwachsenen die häufigsten Auslöser einer Anaphylaxie. Einen wirksamen Schutz vor schweren anaphylaktischen Reaktionen bietet die allergenspezifische Immuntherapie. Jedoch kommt sie noch viel zu selten zum Einsatz.

Therapiestart mit Blutdrucksenkern erhöht Frakturrisiko

25.04.2024 Hypertonie Nachrichten

Beginnen ältere Männer im Pflegeheim eine Antihypertensiva-Therapie, dann ist die Frakturrate in den folgenden 30 Tagen mehr als verdoppelt. Besonders häufig stürzen Demenzkranke und Männer, die erstmals Blutdrucksenker nehmen. Dafür spricht eine Analyse unter US-Veteranen.

Update Innere Medizin

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.