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Erschienen in: Clinical Oral Investigations 8/2013

01.11.2013 | Original Article

Is smoking a predictor of apical periodontitis?

verfasst von: Fabiola-Regina Rodriguez, Babür Taner, Roland Weiger, Clemens Walter

Erschienen in: Clinical Oral Investigations | Ausgabe 8/2013

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Abstract

Objectives

To evaluate the association between cigarette smoking and the frequency of apical periodontitis in female and male patients seeking treatment at the University of Basel (KREBS Project).

Materials and methods

This cohort study included full-mouth periapical radiographs of 161 subjects, including 66 current smokers, 26 former smokers and 69 individuals who had never smoked. The periapical region of all teeth was radiographically evaluated using the Periapical Index (PAI) score. Generalised linear mixed-effects models using the logit link were performed.

Results

The frequency of apical periodontitis differed based on gender and smoking status. Current male cigarette smokers with <10 or ≥10 pack years showed frequencies of apical periodontitis of 12 % and 5.5 %, respectively, compared to 3.8 % in individuals who had never smoked. The corresponding data for female smokers were 5.7 % and 7.2 % in smokers with <10 or ≥10 pack years, respectively, versus 5.2 % in individuals who had never smoked. The factors “prevalent coronal restoration” (p < 0.001), “prevalent root canal treatment” (p < 0.001) and “quality of root canal filling” (p < 0.001) were significant predictors for apical periodontitis. After adjustment for quality of root canal filling cigarette smoking was not associated with apical periodontitis in current female and male smokers with <10 or ≥10 pack years (p > 0.05).

Conclusion

Smoking status did not predict apical periodontitis in females and males in this sample group.

Clinical relevance

With respect to quality of root canal filling, tobacco use may not be a significant predictor for apical periodontitis.
Literatur
1.
Zurück zum Zitat Duncan HF, Pitt Ford TR (2006) The potential association between smoking and endodontic disease. Int Endod J 39:843–854PubMedCrossRef Duncan HF, Pitt Ford TR (2006) The potential association between smoking and endodontic disease. Int Endod J 39:843–854PubMedCrossRef
3.
Zurück zum Zitat Frisk F, Hakeberg M (2006) Socio-economic risk indicators for apical periodontitis. Acta Odontol Scand 64:123–128PubMedCrossRef Frisk F, Hakeberg M (2006) Socio-economic risk indicators for apical periodontitis. Acta Odontol Scand 64:123–128PubMedCrossRef
4.
Zurück zum Zitat López-López J, Jané-Salas E, Estrugo-Devesa A, Castellanos-Cosano L, Martín-González J, Velasco-Ortega E, Segura-Egea JJ (2012) Frequency and distribution of root-filled teeth and apical periodontitis in an adult population of Barcelona, Spain. Int Dent J 62:40–46PubMedCrossRef López-López J, Jané-Salas E, Estrugo-Devesa A, Castellanos-Cosano L, Martín-González J, Velasco-Ortega E, Segura-Egea JJ (2012) Frequency and distribution of root-filled teeth and apical periodontitis in an adult population of Barcelona, Spain. Int Dent J 62:40–46PubMedCrossRef
5.
Zurück zum Zitat Aleksejuniene J, Eriksen HM, Sidaravicius B, Haapasalo M (2000) Apical periodontitis and related factors in an adult Lithuanian population. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 90:95–101PubMedCrossRef Aleksejuniene J, Eriksen HM, Sidaravicius B, Haapasalo M (2000) Apical periodontitis and related factors in an adult Lithuanian population. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 90:95–101PubMedCrossRef
6.
Zurück zum Zitat Bergström J, Babcan J, Eliasson S (2004) Tobacco smoking and dental periapical condition. Eur J Oral Sci 112:115–120PubMedCrossRef Bergström J, Babcan J, Eliasson S (2004) Tobacco smoking and dental periapical condition. Eur J Oral Sci 112:115–120PubMedCrossRef
7.
Zurück zum Zitat Krall EA, Abreu Sosa C, Garcia C, Nunn ME, Caplan DJ, Garcia RI (2006) Cigarette smoking increases the risk of root canal treatment. J Dent Res 85:313–317 Krall EA, Abreu Sosa C, Garcia C, Nunn ME, Caplan DJ, Garcia RI (2006) Cigarette smoking increases the risk of root canal treatment. J Dent Res 85:313–317
8.
Zurück zum Zitat Kirkevang LL, Wenzel A (2003) Risk indicators for apical periodontitis. Community Dent Oral Epidemiol 31:59–67PubMedCrossRef Kirkevang LL, Wenzel A (2003) Risk indicators for apical periodontitis. Community Dent Oral Epidemiol 31:59–67PubMedCrossRef
9.
Zurück zum Zitat Kirkevang LL, Vaeth M, Horsted-Bindslev P, Bahrami G, Wenzel A (2007) Risk factors for developing apical periodontitis in a general population. Int Endod J 40:290–299PubMedCrossRef Kirkevang LL, Vaeth M, Horsted-Bindslev P, Bahrami G, Wenzel A (2007) Risk factors for developing apical periodontitis in a general population. Int Endod J 40:290–299PubMedCrossRef
10.
Zurück zum Zitat Segura-Egea JJ, Jimenez-Pinzon A, Rios-Santos JV, Velasco-Ortega E, Cisneros-Cabello R, Poyato-Ferrera MM (2008) High prevalence of apical periodontitis amongst smokers in a sample of Spanish adults. Int Endod J 41:310–316PubMedCrossRef Segura-Egea JJ, Jimenez-Pinzon A, Rios-Santos JV, Velasco-Ortega E, Cisneros-Cabello R, Poyato-Ferrera MM (2008) High prevalence of apical periodontitis amongst smokers in a sample of Spanish adults. Int Endod J 41:310–316PubMedCrossRef
11.
Zurück zum Zitat Segura-Egea JJ, Castellanos-Cosano L, Velasco-Ortega E, Ríos-Santos JV, Llamas-Carreras JM, Machuca G, López-Frías FJ (2011) Relationship between smoking and endodontic variables in hypertensive patients. J Endod 37:764–767PubMedCrossRef Segura-Egea JJ, Castellanos-Cosano L, Velasco-Ortega E, Ríos-Santos JV, Llamas-Carreras JM, Machuca G, López-Frías FJ (2011) Relationship between smoking and endodontic variables in hypertensive patients. J Endod 37:764–767PubMedCrossRef
12.
Zurück zum Zitat Tomar SL, Asma S (2000) Smoking-attributable periodontitis in the United States: findings from NHANES III. National Health and Nutrition Examination Survey. J Periodontol 71:743–751PubMedCrossRef Tomar SL, Asma S (2000) Smoking-attributable periodontitis in the United States: findings from NHANES III. National Health and Nutrition Examination Survey. J Periodontol 71:743–751PubMedCrossRef
13.
Zurück zum Zitat Warnakulasuriya S, Dietrich T, Bornstein MM et al (2010) Oral health risks of tobacco use and effects of cessation. Int Dent J 60:7–30PubMed Warnakulasuriya S, Dietrich T, Bornstein MM et al (2010) Oral health risks of tobacco use and effects of cessation. Int Dent J 60:7–30PubMed
14.
Zurück zum Zitat Walter C, Krall EA, Dietrich T (2012) Active and passive smoking – assessment issues in periodontal research. Periodontol 2000 58:84–92 Walter C, Krall EA, Dietrich T (2012) Active and passive smoking – assessment issues in periodontal research. Periodontol 2000 58:84–92
15.
Zurück zum Zitat Palmer RM, Wilson RF, Hasan AS, Scott DA (2005) Mechanisms of action of environmental factors — tobacco smoking. J Clin Periodontol 32:180–195PubMedCrossRef Palmer RM, Wilson RF, Hasan AS, Scott DA (2005) Mechanisms of action of environmental factors — tobacco smoking. J Clin Periodontol 32:180–195PubMedCrossRef
16.
Zurück zum Zitat Ryder MI (2007) The influence of smoking on host response in periodontal infections. Periodontol 2000 (43):267–277CrossRef Ryder MI (2007) The influence of smoking on host response in periodontal infections. Periodontol 2000 (43):267–277CrossRef
17.
Zurück zum Zitat Matthews JB, Chen FM, Milward MR, Ling MR, Chapple IL (2012) Neutrophil superoxide production in the presence of cigarette smoke extract, nicotine and cotinine. J Clin Periodontol 39:626–634PubMedCrossRef Matthews JB, Chen FM, Milward MR, Ling MR, Chapple IL (2012) Neutrophil superoxide production in the presence of cigarette smoke extract, nicotine and cotinine. J Clin Periodontol 39:626–634PubMedCrossRef
18.
Zurück zum Zitat Krall EA, Dawson-Hughes B (1999) Smoking increases bone loss and decreases intestinal calcium absorption. J Bone Miner Res 14:215–220PubMedCrossRef Krall EA, Dawson-Hughes B (1999) Smoking increases bone loss and decreases intestinal calcium absorption. J Bone Miner Res 14:215–220PubMedCrossRef
19.
Zurück zum Zitat Payne JB, Johnson GK, Reinhardt RA, Dyer JK, Maze CA, Dunning DG (1996) Nicotine effects on PGE2 and IL-1 beta release by LPS-treated human monocytes. J Periodontal Res 31:99–104PubMedCrossRef Payne JB, Johnson GK, Reinhardt RA, Dyer JK, Maze CA, Dunning DG (1996) Nicotine effects on PGE2 and IL-1 beta release by LPS-treated human monocytes. J Periodontal Res 31:99–104PubMedCrossRef
21.
Zurück zum Zitat Walter C, Krastl G, Weiger R (2008) Step-wise treatment of two periodontal–endodontic lesions in a heavy smoker. Int Endod J 41:1015–1023PubMedCrossRef Walter C, Krastl G, Weiger R (2008) Step-wise treatment of two periodontal–endodontic lesions in a heavy smoker. Int Endod J 41:1015–1023PubMedCrossRef
22.
Zurück zum Zitat Forey B, Hamling J, Hamling J, Lee P (2007) International smoking statistics: a collection of worldwide historical data. Switzerland. Web Edition, 1–40 Forey B, Hamling J, Hamling J, Lee P (2007) International smoking statistics: a collection of worldwide historical data. Switzerland. Web Edition, 1–40
23.
Zurück zum Zitat Meisel P, Reifenberger J, Haase R, Nauck M, Bandt C, Kocher T (2008) Women are periodontally healthier than men, but why don't they have more teeth than men? Menopause 15:270–275PubMedCrossRef Meisel P, Reifenberger J, Haase R, Nauck M, Bandt C, Kocher T (2008) Women are periodontally healthier than men, but why don't they have more teeth than men? Menopause 15:270–275PubMedCrossRef
24.
Zurück zum Zitat Ansari WE, Stock C, Snelgrove S et al (2011) Feeling healthy? A survey of physical and psychological wellbeing of students from seven universities in the UK. Int J Environ Res Public Health 8:1308–1323PubMedCrossRef Ansari WE, Stock C, Snelgrove S et al (2011) Feeling healthy? A survey of physical and psychological wellbeing of students from seven universities in the UK. Int J Environ Res Public Health 8:1308–1323PubMedCrossRef
25.
Zurück zum Zitat Zitzmann NU, Zemp E, Weiger R, Lang NP, Walter C (2011) Does a clinician’s sex influence treatment decisions? Int J Prosthodont 24:507–514PubMed Zitzmann NU, Zemp E, Weiger R, Lang NP, Walter C (2011) Does a clinician’s sex influence treatment decisions? Int J Prosthodont 24:507–514PubMed
26.
Zurück zum Zitat McKay JC, Quiñonez CR (2012) The feminization of dentistry: implications for the profession. J Can Dent Assoc 78:c1 McKay JC, Quiñonez CR (2012) The feminization of dentistry: implications for the profession. J Can Dent Assoc 78:c1
27.
Zurück zum Zitat Ridao-Sacie C, Segura-Egea JJ, Fernández-Palacín A, Bullón-Fernández P, Ríos-Santos JV (2007) Radiological assessment of periapical status using the periapical index: comparison of periapical radiography and digital panoramic radiography. Int Endod J 40:433–440PubMedCrossRef Ridao-Sacie C, Segura-Egea JJ, Fernández-Palacín A, Bullón-Fernández P, Ríos-Santos JV (2007) Radiological assessment of periapical status using the periapical index: comparison of periapical radiography and digital panoramic radiography. Int Endod J 40:433–440PubMedCrossRef
28.
Zurück zum Zitat Rohlin M, Kullendorff B, Ahlquist M, Henrikson CO, Hollender L, Stenström B (1989) Comparison between panoramic and periapical radiography in the diagnosis of periapical bone lesions. Dentomaxillofac Radiol 18:151–155PubMed Rohlin M, Kullendorff B, Ahlquist M, Henrikson CO, Hollender L, Stenström B (1989) Comparison between panoramic and periapical radiography in the diagnosis of periapical bone lesions. Dentomaxillofac Radiol 18:151–155PubMed
29.
Zurück zum Zitat Rodriguez F, Weiger R, Walter C (2012) Lower education level as a risk factor for tooth loss in a Swiss population (Krebs-cohort). Europerio7, 6.6.-9.6.2012, Vienna, Austria, J Clin Periodontol 2012 Issue Supplement s13; 39:81 (PO 266) Rodriguez F, Weiger R, Walter C (2012) Lower education level as a risk factor for tooth loss in a Swiss population (Krebs-cohort). Europerio7, 6.6.-9.6.2012, Vienna, Austria, J Clin Periodontol 2012 Issue Supplement s13; 39:81 (PO 266)
30.
Zurück zum Zitat Ramseier CA, Bornstein MM, Saxer UP, Klingler K, Walter C (2007) Tobacco use prevention and cessation in the dental practice. Schweiz Monatsschr Zahnmed 117:253–278PubMed Ramseier CA, Bornstein MM, Saxer UP, Klingler K, Walter C (2007) Tobacco use prevention and cessation in the dental practice. Schweiz Monatsschr Zahnmed 117:253–278PubMed
31.
Zurück zum Zitat Walter C, Kaner D, Berndt DC, Weiger R, Zitzmann NU (2009) Three-dimensional imaging as a pre-operative tool in decision making for furcation surgery. J Clin Periodontol 36:250–257PubMedCrossRef Walter C, Kaner D, Berndt DC, Weiger R, Zitzmann NU (2009) Three-dimensional imaging as a pre-operative tool in decision making for furcation surgery. J Clin Periodontol 36:250–257PubMedCrossRef
32.
33.
Zurück zum Zitat Ainamo J, Bay I (1975) Problems and proposals for recording gingivitis and plaque. Int Dent J 25:229–235PubMed Ainamo J, Bay I (1975) Problems and proposals for recording gingivitis and plaque. Int Dent J 25:229–235PubMed
34.
Zurück zum Zitat Ørstavik D, Kerekes K, Eriksen HM (1986) The periapical index: a scoring system for radiographic assessment of apical periodontitis. Dent Traumatol 2:20–34CrossRef Ørstavik D, Kerekes K, Eriksen HM (1986) The periapical index: a scoring system for radiographic assessment of apical periodontitis. Dent Traumatol 2:20–34CrossRef
35.
Zurück zum Zitat Ørstavik D (1988) Reliability of the periapical index scoring system. Scand J Dent Res 96:108–111PubMed Ørstavik D (1988) Reliability of the periapical index scoring system. Scand J Dent Res 96:108–111PubMed
36.
Zurück zum Zitat Tronstad L, Asbjornsen K, Doving L, Pedersen I, Eriksen HM (2000) Influence of coronal restorations on the periapical health of endodontically treated teeth. Endod Dent Traumatol 16:218–221PubMedCrossRef Tronstad L, Asbjornsen K, Doving L, Pedersen I, Eriksen HM (2000) Influence of coronal restorations on the periapical health of endodontically treated teeth. Endod Dent Traumatol 16:218–221PubMedCrossRef
37.
Zurück zum Zitat Segura-Egea JJ, Jiménez-Pinzón A, Ríos-Santos JV, Velasco-Ortega E, Cisneros-Cabello R, Poyato-Ferrera M (2005) High prevalence of apical periodontitis amongst type 2 diabetic patients. Int Endod J 38:564–569PubMedCrossRef Segura-Egea JJ, Jiménez-Pinzón A, Ríos-Santos JV, Velasco-Ortega E, Cisneros-Cabello R, Poyato-Ferrera M (2005) High prevalence of apical periodontitis amongst type 2 diabetic patients. Int Endod J 38:564–569PubMedCrossRef
38.
Zurück zum Zitat Weiger R, Hitzler S, Hermle G, Löst C (1997) Periapical status, quality of root canal fillings and estimated endodontic treatment needs in an urban German population. Endod Dent Traumatol 13:69–74PubMedCrossRef Weiger R, Hitzler S, Hermle G, Löst C (1997) Periapical status, quality of root canal fillings and estimated endodontic treatment needs in an urban German population. Endod Dent Traumatol 13:69–74PubMedCrossRef
39.
Zurück zum Zitat Everitt BS (1968) Moments of statistics kappa and weighted kappa. Br J Math Stat Psychol, 97–103 Everitt BS (1968) Moments of statistics kappa and weighted kappa. Br J Math Stat Psychol, 97–103
40.
Zurück zum Zitat Broemeling LD (2007) Bayesian biostatistics and diagnostic medicine. Chapman and Hall/CRC, p 119 Broemeling LD (2007) Bayesian biostatistics and diagnostic medicine. Chapman and Hall/CRC, p 119
41.
Zurück zum Zitat Johnson GK Gutmiller JM (2007) The impact of cigarette smoking on periodontal disease and treatment. Periodontol 2000 44:178–194CrossRef Johnson GK Gutmiller JM (2007) The impact of cigarette smoking on periodontal disease and treatment. Periodontol 2000 44:178–194CrossRef
42.
Zurück zum Zitat Dietrich T, Hoffmann K (2004) A comprehensive index for the modeling of smoking history in periodontal research. J Dent Res 83:859–863PubMedCrossRef Dietrich T, Hoffmann K (2004) A comprehensive index for the modeling of smoking history in periodontal research. J Dent Res 83:859–863PubMedCrossRef
43.
Zurück zum Zitat Marending M, Peters OA, Zehnder M (2005) Factors affecting the outcome of orthograde root canal therapy in a general dentistry hospital practice. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 99:119–124PubMedCrossRef Marending M, Peters OA, Zehnder M (2005) Factors affecting the outcome of orthograde root canal therapy in a general dentistry hospital practice. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 99:119–124PubMedCrossRef
44.
Zurück zum Zitat Enberg N, Wolf J, Ainamo A, Alho H, Heinälä P, Lenander-Lumikari M (2001) Dental diseases and loss of teeth in a group of Finnish alcoholics: a radiological study. Acta Odontol Scand 59:341–347PubMedCrossRef Enberg N, Wolf J, Ainamo A, Alho H, Heinälä P, Lenander-Lumikari M (2001) Dental diseases and loss of teeth in a group of Finnish alcoholics: a radiological study. Acta Odontol Scand 59:341–347PubMedCrossRef
45.
Zurück zum Zitat Ng YL, Mann V, Rahbaran S, Lewsey J, Gulabivala K (2008) Outcome of primary root canal treatment: systematic review of the literature — Part 2. Influence of clinical factors. Int Endod J 41:6–31PubMedCrossRef Ng YL, Mann V, Rahbaran S, Lewsey J, Gulabivala K (2008) Outcome of primary root canal treatment: systematic review of the literature — Part 2. Influence of clinical factors. Int Endod J 41:6–31PubMedCrossRef
46.
Zurück zum Zitat Rees JS, Thomas M, Naik P (2011) A prospective study of the prevalence of periapical pathology in severely worn teeth. Dent Update 38:24–26PubMed Rees JS, Thomas M, Naik P (2011) A prospective study of the prevalence of periapical pathology in severely worn teeth. Dent Update 38:24–26PubMed
47.
Zurück zum Zitat Lee BD, White SC (2005) Age and trabecular features of alveolar bone associated with osteoporosis. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 100:92–98PubMedCrossRef Lee BD, White SC (2005) Age and trabecular features of alveolar bone associated with osteoporosis. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 100:92–98PubMedCrossRef
48.
Zurück zum Zitat Jonasson G, Jonasson L, Kiliaridis S (2007) Skeletal bone mineral density in relation to thickness, bone mass, and structure of the mandibular alveolar process in dentate men and women. Eur J Oral Sci 115:117–123PubMedCrossRef Jonasson G, Jonasson L, Kiliaridis S (2007) Skeletal bone mineral density in relation to thickness, bone mass, and structure of the mandibular alveolar process in dentate men and women. Eur J Oral Sci 115:117–123PubMedCrossRef
49.
Zurück zum Zitat Bergström J, Eliasson S, Ahlberg KF (1987) Periapical status in subjects with regular dental care habits. Community Dent Oral Epidemiol 15:236–239PubMedCrossRef Bergström J, Eliasson S, Ahlberg KF (1987) Periapical status in subjects with regular dental care habits. Community Dent Oral Epidemiol 15:236–239PubMedCrossRef
50.
Zurück zum Zitat Peciuliene V, Rimkuviene J, Maneliene R, Ivanauskaite D (2006) Apical periodontitis in root filled teeth associated with the quality of root fillings. Stomatologija 8:122–126PubMed Peciuliene V, Rimkuviene J, Maneliene R, Ivanauskaite D (2006) Apical periodontitis in root filled teeth associated with the quality of root fillings. Stomatologija 8:122–126PubMed
Metadaten
Titel
Is smoking a predictor of apical periodontitis?
verfasst von
Fabiola-Regina Rodriguez
Babür Taner
Roland Weiger
Clemens Walter
Publikationsdatum
01.11.2013
Verlag
Springer Berlin Heidelberg
Erschienen in
Clinical Oral Investigations / Ausgabe 8/2013
Print ISSN: 1432-6981
Elektronische ISSN: 1436-3771
DOI
https://doi.org/10.1007/s00784-012-0893-z

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