Skip to main content
Erschienen in: Emergency Radiology 6/2017

01.12.2017 | Original Article

Assessing 3D T2 FSE sequence for identification of the normal appendix: working toward a single-sequence MR appendicitis protocol

verfasst von: Nattinee Leelakanok, Andrew S. Phelps, Matthew A. Zapala, Kambrie Kato, Michael Ohliger, Yi Li, Jesse Courtier

Erschienen in: Emergency Radiology | Ausgabe 6/2017

Einloggen, um Zugang zu erhalten

Abstract

Purposes

To assess the ability of a single isotropic 3D T2 FSE sequence to identify the normal appendix in children with potential implication as alternative second-line modality in pediatric appendicitis.

Materials and methods

Retrospective review of MR abdomino-pelvis or pelvis in children from Oct 2014–Dec 2016 was done. Only exams with 3D T2 FSE sequence performed on a single scanner type were selected. Patients with history of post appendectomy, studies in which field of view did not include ileocecal valve, with technical and protocol errors, or with fat-saturated acquisition were excluded. All images were blindly reviewed by three radiologists. The following questions were asked: (1) Is the appendix visualized?, (2) What is the most clearly demonstrable plane?, (3) Where is the appendix located?, (4) Are there any findings indicating appendicitis? Average pairwise percentage and Fleiss Kappa were used to assess the inter-rater agreement on the visualization and location of the appendix.

Results

A total of 22 MRI studies were reviewed (F = 13:M = 9, Mean age = 11.45 yrs. [SD = 4.3]). Total MRI scan time was estimated at 6 mins. Readers saw appendix in 72.7–81.8%, and saw with high confidence in 12 cases (54.5%), low confidence in 4–6 case (18.2–27.3%), and did not see in 4–6 cases(18.2–27.3%). The average pairwise percentage agreement was 71.2%. Fleiss Kappa of overall rating of visualization was 0.52 (p < 0.001). Fleiss Kappa of high confidence of visualization was 0.76 (p < 0.001). Reader 1 and reader 2 saw the appendix best on the axial plane. Reader 3 saw the appendix best on the coronal plane. For location, deep pelvis was the most common identified location. The average pairwise percentage agreement was 68.2% and Fleiss Kappa was 0.76 (p < 0.001). There is no findings indicating appendicitis.

Conclusion

A single 3D T2 FSE sequence had good ability to detect normal appendices and also allowed multiplanar reconstructions, which may use as a single-sequence protocol in cases of suspected appendicitis in children when ultrasound is inconclusive.
Literatur
1.
Zurück zum Zitat Herliczek TW, Swenson DW, Mayo-Smith WW (2013) Utility of MRI after inconclusive ultrasound in pediatric patients with suspected appendicitis: retrospective review of 60 consecutive patients. AJR Am J Roentgenol 200:969–973CrossRefPubMed Herliczek TW, Swenson DW, Mayo-Smith WW (2013) Utility of MRI after inconclusive ultrasound in pediatric patients with suspected appendicitis: retrospective review of 60 consecutive patients. AJR Am J Roentgenol 200:969–973CrossRefPubMed
2.
Zurück zum Zitat Swenson DW, Schooler GR, Stamoulis C, Lee EY (2016) MRI of the normal appendix in children: data toward a new reference standard. Pediatr Radiol 46:1003–1010CrossRefPubMed Swenson DW, Schooler GR, Stamoulis C, Lee EY (2016) MRI of the normal appendix in children: data toward a new reference standard. Pediatr Radiol 46:1003–1010CrossRefPubMed
3.
Zurück zum Zitat Pinto Leite N, Leite NP, Pereira JM et al (2005) CT evaluation of appendicitis and its complications: imaging techniques and key diagnostic findings. Am J Roentgenol 185:406–417CrossRef Pinto Leite N, Leite NP, Pereira JM et al (2005) CT evaluation of appendicitis and its complications: imaging techniques and key diagnostic findings. Am J Roentgenol 185:406–417CrossRef
4.
Zurück zum Zitat Doria AS, Moineddin R, Kellenberger CJ et al (2006) US or CT for diagnosis of appendicitis in children and adults? A meta-analysis. Radiology 241:83–94CrossRefPubMed Doria AS, Moineddin R, Kellenberger CJ et al (2006) US or CT for diagnosis of appendicitis in children and adults? A meta-analysis. Radiology 241:83–94CrossRefPubMed
5.
Zurück zum Zitat Orth RC, Guillerman RP, Zhang W et al (2015) Prospective comparison of MR imaging and US for the diagnosis of pediatric appendicitis. Radiology 277:927CrossRefPubMed Orth RC, Guillerman RP, Zhang W et al (2015) Prospective comparison of MR imaging and US for the diagnosis of pediatric appendicitis. Radiology 277:927CrossRefPubMed
6.
Zurück zum Zitat Cobben LP, Groot I, Haans L et al (2004) MRI for clinically suspected appendicitis during pregnancy. Am J Roentgenol 183:671–675CrossRef Cobben LP, Groot I, Haans L et al (2004) MRI for clinically suspected appendicitis during pregnancy. Am J Roentgenol 183:671–675CrossRef
7.
Zurück zum Zitat Nitta N, Takahashi M, Furukawa A et al (2005) MR imaging of the normal appendix and acute appendicitis. J Magn Reson Imaging 21:156–165CrossRefPubMed Nitta N, Takahashi M, Furukawa A et al (2005) MR imaging of the normal appendix and acute appendicitis. J Magn Reson Imaging 21:156–165CrossRefPubMed
8.
Zurück zum Zitat Nikolaidis P, Hammond N, Marko J et al (2006) Incidence of visualization of the normal appendix on different MRI sequences. Emerg Radiol 12:223–226CrossRefPubMed Nikolaidis P, Hammond N, Marko J et al (2006) Incidence of visualization of the normal appendix on different MRI sequences. Emerg Radiol 12:223–226CrossRefPubMed
9.
Zurück zum Zitat Cobben L, Groot I, Kingma L et al (2009) A simple MRI protocol in patients with clinically suspected appendicitis: results in 138 patients and effect on outcome of appendectomy. Eur Radiol 19:1175–1183CrossRefPubMed Cobben L, Groot I, Kingma L et al (2009) A simple MRI protocol in patients with clinically suspected appendicitis: results in 138 patients and effect on outcome of appendectomy. Eur Radiol 19:1175–1183CrossRefPubMed
10.
Zurück zum Zitat Freelon D (2010) ReCal: intercoder reliability calculation as a web service. International Journal of Internet Science 5:20–33 Freelon D (2010) ReCal: intercoder reliability calculation as a web service. International Journal of Internet Science 5:20–33
11.
Zurück zum Zitat Viera AJ, Garrett JM (2005) Understanding interobserver agreement: the kappa statistic. Fam Med 37:360–363PubMed Viera AJ, Garrett JM (2005) Understanding interobserver agreement: the kappa statistic. Fam Med 37:360–363PubMed
12.
Zurück zum Zitat Zapf A, Castell S, Morawietz L, Karch A (2016) Measuring inter-rater reliability for nominal data—which coefficients and confidence intervals are appropriate? BMC Med Res Methodol. doi:10.1186/s12874-016-0200-9 Zapf A, Castell S, Morawietz L, Karch A (2016) Measuring inter-rater reliability for nominal data—which coefficients and confidence intervals are appropriate? BMC Med Res Methodol. doi:10.​1186/​s12874-016-0200-9
13.
14.
Zurück zum Zitat Joo S-M, Lee KH, Kim YH et al (2009) Detection of the normal appendix with low-dose unenhanced CT: use of the sliding slab averaging technique. Radiology 251:780–787CrossRefPubMed Joo S-M, Lee KH, Kim YH et al (2009) Detection of the normal appendix with low-dose unenhanced CT: use of the sliding slab averaging technique. Radiology 251:780–787CrossRefPubMed
15.
Zurück zum Zitat Karabulut N, Boyaci N, Yagci B et al (2007) Computed tomography evaluation of the normal appendix: comparison of low-dose and standard-dose unenhanced helical computed tomography. J Comput Assist Tomogr 31:732–740CrossRefPubMed Karabulut N, Boyaci N, Yagci B et al (2007) Computed tomography evaluation of the normal appendix: comparison of low-dose and standard-dose unenhanced helical computed tomography. J Comput Assist Tomogr 31:732–740CrossRefPubMed
16.
Zurück zum Zitat Smith EA, Dillman JR (2016) Current role of body MRI in pediatric oncology. Pediatr Radiol 46:873–880CrossRefPubMed Smith EA, Dillman JR (2016) Current role of body MRI in pediatric oncology. Pediatr Radiol 46:873–880CrossRefPubMed
17.
Zurück zum Zitat Johnson AK, Filippi CG, Andrews T et al (2012) Ultrafast 3-T MRI in the evaluation of children with acute lower abdominal pain for the detection of appendicitis. AJR Am J Roentgenol 198:1424–1430CrossRefPubMed Johnson AK, Filippi CG, Andrews T et al (2012) Ultrafast 3-T MRI in the evaluation of children with acute lower abdominal pain for the detection of appendicitis. AJR Am J Roentgenol 198:1424–1430CrossRefPubMed
18.
Zurück zum Zitat Semelka RC, Armao DM, Elias J Jr, Huda W (2007) Imaging strategies to reduce the risk of radiation in CT studies, including selective substitution with MRI. J Magn Reson Imaging 25:900–909CrossRefPubMed Semelka RC, Armao DM, Elias J Jr, Huda W (2007) Imaging strategies to reduce the risk of radiation in CT studies, including selective substitution with MRI. J Magn Reson Imaging 25:900–909CrossRefPubMed
19.
Zurück zum Zitat Baldisserotto M, Valduga SG, da Cunha CFJS (2008) MR imaging evaluation of the normal appendix in children and adolescents. Radiology 249:278–284CrossRefPubMed Baldisserotto M, Valduga SG, da Cunha CFJS (2008) MR imaging evaluation of the normal appendix in children and adolescents. Radiology 249:278–284CrossRefPubMed
20.
Zurück zum Zitat Moore MM, Kulaylat AN, Hollenbeak CS et al (2016) Magnetic resonance imaging in pediatric appendicitis: a systematic review. Pediatr Radiol 46:928–939CrossRefPubMed Moore MM, Kulaylat AN, Hollenbeak CS et al (2016) Magnetic resonance imaging in pediatric appendicitis: a systematic review. Pediatr Radiol 46:928–939CrossRefPubMed
21.
Zurück zum Zitat Rosenkrantz AB, Neil J, Kong X et al (2010) Prostate cancer: comparison of 3D T2-weighted with conventional 2D T2-weighted imaging for image quality and tumor detection. AJR Am J Roentgenol 194:446–452CrossRefPubMed Rosenkrantz AB, Neil J, Kong X et al (2010) Prostate cancer: comparison of 3D T2-weighted with conventional 2D T2-weighted imaging for image quality and tumor detection. AJR Am J Roentgenol 194:446–452CrossRefPubMed
22.
Zurück zum Zitat Johnson G, Wadghiri YZ, Turnbull DH (1999) 2D multislice and 3D MRI sequences are often equally sensitive. Magn Reson Med 41:824–828CrossRefPubMed Johnson G, Wadghiri YZ, Turnbull DH (1999) 2D multislice and 3D MRI sequences are often equally sensitive. Magn Reson Med 41:824–828CrossRefPubMed
23.
Zurück zum Zitat Hori M, Kim T, Onishi H et al (2011) Uterine tumors: comparison of 3D versus 2D T2-weighted turbo spin-echo MR imaging at 3.0 T—initial experience. Radiology 258:154–163CrossRefPubMed Hori M, Kim T, Onishi H et al (2011) Uterine tumors: comparison of 3D versus 2D T2-weighted turbo spin-echo MR imaging at 3.0 T—initial experience. Radiology 258:154–163CrossRefPubMed
25.
Zurück zum Zitat Lyons GR, Renjen P, Askin G et al (2017) Diagnostic utility of intravenous contrast for MR imaging in pediatric appendicitis. Pediatr Radiol 47:398–403CrossRefPubMed Lyons GR, Renjen P, Askin G et al (2017) Diagnostic utility of intravenous contrast for MR imaging in pediatric appendicitis. Pediatr Radiol 47:398–403CrossRefPubMed
26.
Zurück zum Zitat Rosines LA, Chow DS, Lampl BS et al (2014) Value of gadolinium-enhanced MRI in detection of acute appendicitis in children and adolescents. AJR Am J Roentgenol 203:W543–W548CrossRefPubMed Rosines LA, Chow DS, Lampl BS et al (2014) Value of gadolinium-enhanced MRI in detection of acute appendicitis in children and adolescents. AJR Am J Roentgenol 203:W543–W548CrossRefPubMed
27.
Zurück zum Zitat O’Malley ME, Alharbi F, Chawla TP, Moshonov H (2016) CT following US for possible appendicitis: anatomic coverage. Eur Radiol 26:532–538CrossRefPubMed O’Malley ME, Alharbi F, Chawla TP, Moshonov H (2016) CT following US for possible appendicitis: anatomic coverage. Eur Radiol 26:532–538CrossRefPubMed
28.
Zurück zum Zitat Davis J, Roh AT, Petterson MB et al (2017) Computed tomography localization of the appendix in the pediatric population relative to the lumbar spine. Pediatr Radiol 47:301–305CrossRefPubMed Davis J, Roh AT, Petterson MB et al (2017) Computed tomography localization of the appendix in the pediatric population relative to the lumbar spine. Pediatr Radiol 47:301–305CrossRefPubMed
Metadaten
Titel
Assessing 3D T2 FSE sequence for identification of the normal appendix: working toward a single-sequence MR appendicitis protocol
verfasst von
Nattinee Leelakanok
Andrew S. Phelps
Matthew A. Zapala
Kambrie Kato
Michael Ohliger
Yi Li
Jesse Courtier
Publikationsdatum
01.12.2017
Verlag
Springer Berlin Heidelberg
Erschienen in
Emergency Radiology / Ausgabe 6/2017
Print ISSN: 1070-3004
Elektronische ISSN: 1438-1435
DOI
https://doi.org/10.1007/s10140-017-1538-y

Weitere Artikel der Ausgabe 6/2017

Emergency Radiology 6/2017 Zur Ausgabe

Darf man die Behandlung eines Neonazis ablehnen?

08.05.2024 Gesellschaft Nachrichten

In einer Leseranfrage in der Zeitschrift Journal of the American Academy of Dermatology möchte ein anonymer Dermatologe bzw. eine anonyme Dermatologin wissen, ob er oder sie einen Patienten behandeln muss, der eine rassistische Tätowierung trägt.

Ein Drittel der jungen Ärztinnen und Ärzte erwägt abzuwandern

07.05.2024 Klinik aktuell Nachrichten

Extreme Arbeitsverdichtung und kaum Supervision: Dr. Andrea Martini, Sprecherin des Bündnisses Junge Ärztinnen und Ärzte (BJÄ) über den Frust des ärztlichen Nachwuchses und die Vorteile des Rucksack-Modells.

Endlich: Zi zeigt, mit welchen PVS Praxen zufrieden sind

IT für Ärzte Nachrichten

Darauf haben viele Praxen gewartet: Das Zi hat eine Liste von Praxisverwaltungssystemen veröffentlicht, die von Nutzern positiv bewertet werden. Eine gute Grundlage für wechselwillige Ärztinnen und Psychotherapeuten.

Akuter Schwindel: Wann lohnt sich eine MRT?

28.04.2024 Schwindel Nachrichten

Akuter Schwindel stellt oft eine diagnostische Herausforderung dar. Wie nützlich dabei eine MRT ist, hat eine Studie aus Finnland untersucht. Immerhin einer von sechs Patienten wurde mit akutem ischämischem Schlaganfall diagnostiziert.

Update Radiologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.