Skip to main content
Erschienen in: The European Journal of Health Economics 1/2010

01.01.2010 | Original Paper

The dynamics of colorectal cancer management in 17 countries

verfasst von: Panos Kanavos, Willemien Schurer

Erschienen in: The European Journal of Health Economics | Sonderheft 1/2010

Einloggen, um Zugang zu erhalten

Abstract

This paper discusses the current care management arrangements for colorectal cancer (CRC) in 16 OECD countries plus the Russian Federation by analysing data sources, the uptake of screening and surveillance, the available capacity in endoscopy services, the treatment pathways in medical treatment, as well as the type and availability of pharmaceutical care. The paper highlights significant variations in practice across the 17 countries. Common themes emerge from each of these practices and standards in terms of political interest in policies and awareness of CRC (both of which need to be enhanced), affordability (in terms of scarcity of resources in some countries and out-of-pocket payments for parts of the overall treatment process), access (in terms of the significant variation that has been observed within and across countries with regard to diagnostics, treatment and certain pharmaceuticals) and quality of CRC services (which may arise due to variations in treatment and pharmaceutical guidelines as well as minimal monitoring). When considering policy options for the future, it is important to, first, improve data collection both within as well as across countries through international co-operation; second, it is critical to have greater national and international support for cancer screening activities proven to be effective and cost-effective; third, endoscopy capacity in individual countries needs to be improved, also allowing more choice to ensure timely diagnosis, regardless of screening activities; fourth, public and political awareness needs to be enhanced as it is the key to improving CRC outcomes; fifth, where appropriate, to give consideration to the principles of equity, human dignity and disease severity, among others, when deciding on the uptake of new (targeted) treatments, rather than base decisions solely on cost-effectiveness criteria; and sixth, to firm up national guidelines including screening, diagnosis, treatment, pharmaceutical treatments and surveillance, with a view to enhancing their timeliness, evidence-base and free access to all.
Fußnoten
1
Cancer and CRC incidence and mortality were chosen as proxies for country cancer population burdens. In countries with particularly poor-quality cancer registry data (Hungary, Russia) these estimates may be less accurate; however, for the remaining countries this correction gives an estimate of cancer spending per incident (first year of cancer) and mortality (last year of cancer) when spending is likely to be the highest.
 
Literatur
1.
Zurück zum Zitat Ferlay, J., Autier, P., Boniol, M., et al.: Estimates of the cancer incidence and mortality in Europe in 2006. Ann. Oncol. (2007) Ferlay, J., Autier, P., Boniol, M., et al.: Estimates of the cancer incidence and mortality in Europe in 2006. Ann. Oncol. (2007)
2.
Zurück zum Zitat Verdecchia, A., Francisci, S., Brenner, H., et al.: Recent cancer survival in Europe: a 2000–2002 period analysis of EUROCARE-4 data. Lancet Oncol. (2007) Verdecchia, A., Francisci, S., Brenner, H., et al.: Recent cancer survival in Europe: a 2000–2002 period analysis of EUROCARE-4 data. Lancet Oncol. (2007)
3.
Zurück zum Zitat Sant, M., Aereleid, T., Berrino, F., et al.: EUROCARE-3: survival of cancer patients diagnosed 1990–1994—results and commentary. Ann. Oncol. 14(S5), v61–118 (2003) Sant, M., Aereleid, T., Berrino, F., et al.: EUROCARE-3: survival of cancer patients diagnosed 1990–1994—results and commentary. Ann. Oncol. 14(S5), v61–118 (2003)
4.
Zurück zum Zitat Streetly, A, Holland, W.: Population screening and public health. In: Oxford Textbook of Public Health, vol. 3, chapter 12.7. Oxford University Press (2009) Streetly, A, Holland, W.: Population screening and public health. In: Oxford Textbook of Public Health, vol. 3, chapter 12.7. Oxford University Press (2009)
5.
Zurück zum Zitat Gatta, G., Ciccolallo, L., Capocaccia, R., et al.: Differences in colorectal cancer survival between European and US populations: the importance of sub-site and morphology. Eur. J. Cancer 39, 2214–2222 (2003)CrossRef Gatta, G., Ciccolallo, L., Capocaccia, R., et al.: Differences in colorectal cancer survival between European and US populations: the importance of sub-site and morphology. Eur. J. Cancer 39, 2214–2222 (2003)CrossRef
6.
Zurück zum Zitat Council of the European Union: Council recommendation of 2 December 2003 on cancer screening. Official J. EU 327, 34–38 (2003) Council of the European Union: Council recommendation of 2 December 2003 on cancer screening. Official J. EU 327, 34–38 (2003)
8.
Zurück zum Zitat European Group for Colorectal Screening: Recommendation to include colorectal cancer screening in public health policy. J. Med. Screen. 6, 80–81 (1999) European Group for Colorectal Screening: Recommendation to include colorectal cancer screening in public health policy. J. Med. Screen. 6, 80–81 (1999)
9.
Zurück zum Zitat Perry, N., Broeders, M., de Wolf, C., et al. (eds.): European guidelines for quality assurance in breast cancer screening and diagnosis, 4th edn. Office for Official Publications of the European Communities, Luxembourg (2006) Perry, N., Broeders, M., de Wolf, C., et al. (eds.): European guidelines for quality assurance in breast cancer screening and diagnosis, 4th edn. Office for Official Publications of the European Communities, Luxembourg (2006)
10.
Zurück zum Zitat Kanavos, P., Schurer, W., Owusu-Apenten, C., et al.: Colorectal cancer in Europe and Australia: challenges and opportunities for the future. London School of Economics, LSE Health, London (2008) Kanavos, P., Schurer, W., Owusu-Apenten, C., et al.: Colorectal cancer in Europe and Australia: challenges and opportunities for the future. London School of Economics, LSE Health, London (2008)
11.
Zurück zum Zitat European Commission: Cancer screening in the European Union: report on the implementation of the council recommendation on cancer screening—first report. Brussels (2008) European Commission: Cancer screening in the European Union: report on the implementation of the council recommendation on cancer screening—first report. Brussels (2008)
12.
Zurück zum Zitat Australian Institute of Health and Welfare, Australian Government Department of Health and Aging for the National Bowel Cancer Screening Program: National bowel cancer screening program monitoring report 2007. Cancer series, number 40, Canberra (2008) Australian Institute of Health and Welfare, Australian Government Department of Health and Aging for the National Bowel Cancer Screening Program: National bowel cancer screening program monitoring report 2007. Cancer series, number 40, Canberra (2008)
13.
Zurück zum Zitat Gyrd-Hansen, D., Sogaard, J., Kronborg, O.: Colorectal cancer screening: efficiency and effectiveness. Health Econ. 7, 9–20 (1998)CrossRef Gyrd-Hansen, D., Sogaard, J., Kronborg, O.: Colorectal cancer screening: efficiency and effectiveness. Health Econ. 7, 9–20 (1998)CrossRef
14.
Zurück zum Zitat Lejeune, C., Arveux, P., Dancourt, V., et al.: Cost effectiveness analysis of fecal occult blood screening for colorectal cancer. Int. J. Tech. Assoc. Health Care 20, 434–439 (2004) Lejeune, C., Arveux, P., Dancourt, V., et al.: Cost effectiveness analysis of fecal occult blood screening for colorectal cancer. Int. J. Tech. Assoc. Health Care 20, 434–439 (2004)
15.
Zurück zum Zitat Berchi, C., Bouvier, V., Réaud, J.M.: Cost effectiveness analysis of two strategies for mass screening for colorectal cancer in France. Health Econ. 13, 227–238 (2004)CrossRef Berchi, C., Bouvier, V., Réaud, J.M.: Cost effectiveness analysis of two strategies for mass screening for colorectal cancer in France. Health Econ. 13, 227–238 (2004)CrossRef
16.
Zurück zum Zitat Stone, C.A., Carter, R.C., Vos, T., et al.: Colorectal cancer screening in Australia: an economic evaluation of a potential biennial screening program using faecal occult blood tests. Aust. N. Z. J. Public Health 28, 273–282 (2004) Stone, C.A., Carter, R.C., Vos, T., et al.: Colorectal cancer screening in Australia: an economic evaluation of a potential biennial screening program using faecal occult blood tests. Aust. N. Z. J. Public Health 28, 273–282 (2004)
17.
Zurück zum Zitat Whynes, D.K., Neilson, A.R., Walker, A.R., et al.: Faecal occult blood screening for colorectal cancer: is it cost-effective? Health Econ. 7, 21–29 (1998)CrossRef Whynes, D.K., Neilson, A.R., Walker, A.R., et al.: Faecal occult blood screening for colorectal cancer: is it cost-effective? Health Econ. 7, 21–29 (1998)CrossRef
18.
Zurück zum Zitat Whynes, D.K., Nottingham, F.O.B.: Screening trial: cost-effectiveness of screening for colorectal cancer: evidence from the Nottingham faecal occult blood trial. J. Med. Screen. 11, 11–15 (2004)CrossRef Whynes, D.K., Nottingham, F.O.B.: Screening trial: cost-effectiveness of screening for colorectal cancer: evidence from the Nottingham faecal occult blood trial. J. Med. Screen. 11, 11–15 (2004)CrossRef
19.
Zurück zum Zitat Tappenden, P., Chilcott, J., Eggington, S., et al.: Option appraisal of population based colorectal cancer screening programmes in England. Gut 56, 677–684 (2007)CrossRef Tappenden, P., Chilcott, J., Eggington, S., et al.: Option appraisal of population based colorectal cancer screening programmes in England. Gut 56, 677–684 (2007)CrossRef
20.
Zurück zum Zitat O’Leary, B.A., Olynyk, J.K., Neville, A.M., et al.: Cost-effectiveness of colorectal cancer screening: comparison of community-based flexible sigmoidoscopy with fecal occult blood testing and colonoscopy. J. Gastroenterol. Hepatol. 19, 38–47 (2004)CrossRef O’Leary, B.A., Olynyk, J.K., Neville, A.M., et al.: Cost-effectiveness of colorectal cancer screening: comparison of community-based flexible sigmoidoscopy with fecal occult blood testing and colonoscopy. J. Gastroenterol. Hepatol. 19, 38–47 (2004)CrossRef
21.
Zurück zum Zitat Norum, J.: Prevention of colorectal cancer: a cost-effectiveness approach to a screening model employing sigmoidoscopy. Ann. Oncol. 9, 613–618 (1998)CrossRef Norum, J.: Prevention of colorectal cancer: a cost-effectiveness approach to a screening model employing sigmoidoscopy. Ann. Oncol. 9, 613–618 (1998)CrossRef
22.
Zurück zum Zitat Hassan, C., Zullo, A., Laghi, A., et al.: Colon cancer prevention in Italy: Cost-effectiveness analysis with CT colonography and endoscopy. Dig. Liver Dis. 39, 242–250 (2007) Hassan, C., Zullo, A., Laghi, A., et al.: Colon cancer prevention in Italy: Cost-effectiveness analysis with CT colonography and endoscopy. Dig. Liver Dis. 39, 242–250 (2007)
23.
Zurück zum Zitat Denis, B.J., Ruetsch, M., Strentz, P., et al.: Short term outcomes of the first round of a pilot colorectal cancer screening programme with guaiac based faecal occult blood test. Gut 56, 1579–1584 (2007)CrossRef Denis, B.J., Ruetsch, M., Strentz, P., et al.: Short term outcomes of the first round of a pilot colorectal cancer screening programme with guaiac based faecal occult blood test. Gut 56, 1579–1584 (2007)CrossRef
25.
Zurück zum Zitat Segnan, N., Senore, C., Androni, B., et al.: Randomized trial of different strategies for colorectal cancer: patient response and detection rates. J. Natl Cancer Inst. 97, 347–357 (2005) Segnan, N., Senore, C., Androni, B., et al.: Randomized trial of different strategies for colorectal cancer: patient response and detection rates. J. Natl Cancer Inst. 97, 347–357 (2005)
26.
Zurück zum Zitat UK Flexible Sigmoidoscopy Screening Trial Investigators: Single flexible sigmoidoscopy screening to prevent colorectal cancer: baseline findings of a UK muticentre randomised trial. Lancet 359, 1291–1300 (2002)CrossRef UK Flexible Sigmoidoscopy Screening Trial Investigators: Single flexible sigmoidoscopy screening to prevent colorectal cancer: baseline findings of a UK muticentre randomised trial. Lancet 359, 1291–1300 (2002)CrossRef
27.
Zurück zum Zitat Zorzi, M., Falcini, F., Fedato, C., et al.: Screening for colorectal cancer in Italy: 2006 survey. Epidemiol. Prev. 32(S1), 55–68 (2008) Zorzi, M., Falcini, F., Fedato, C., et al.: Screening for colorectal cancer in Italy: 2006 survey. Epidemiol. Prev. 32(S1), 55–68 (2008)
28.
Zurück zum Zitat European Commission: Health in the European Union. Special Eurobarometer 272e/Wave 66.2 (2007) European Commission: Health in the European Union. Special Eurobarometer 272e/Wave 66.2 (2007)
29.
Zurück zum Zitat Geitona, M., Kanavos, P.: Colorectal cancer management and prevention policies in Greece (this issue) Geitona, M., Kanavos, P.: Colorectal cancer management and prevention policies in Greece (this issue)
30.
Zurück zum Zitat Verastegui, E., Mohar, A.: Colorectal cancer in Mexico: should a middle income country invest in screening or treatment? (this issue) Verastegui, E., Mohar, A.: Colorectal cancer in Mexico: should a middle income country invest in screening or treatment? (this issue)
31.
Zurück zum Zitat Avkentieva, M.: Colorectal cancer in Russia (this issue) Avkentieva, M.: Colorectal cancer in Russia (this issue)
32.
Zurück zum Zitat Tatar, M., Tatar, F.: Colorectal cancer in Turkey: current situation and challenges for the future (this issue) Tatar, M., Tatar, F.: Colorectal cancer in Turkey: current situation and challenges for the future (this issue)
33.
Zurück zum Zitat Chevreul, K.: Colorectal cancer in France (this issue) Chevreul, K.: Colorectal cancer in France (this issue)
34.
Zurück zum Zitat Masseria, C.: Colorectal cancer in Italy: a review of current national and regional practices on screening and treatment (this issue) Masseria, C.: Colorectal cancer in Italy: a review of current national and regional practices on screening and treatment (this issue)
35.
Zurück zum Zitat Schurer, W., Kanavos, P.: Evolution of colorectal cancer care in the United Kingdom (this issue) Schurer, W., Kanavos, P.: Evolution of colorectal cancer care in the United Kingdom (this issue)
36.
Zurück zum Zitat Schulenburg, M.G., Prenzler, A., Schurer, W.: Cancer management and reimbursement aspects in Germany—an overview of colorectal cancer (this issue) Schulenburg, M.G., Prenzler, A., Schurer, W.: Cancer management and reimbursement aspects in Germany—an overview of colorectal cancer (this issue)
37.
Zurück zum Zitat Ruszkowski, J.: Colorectal cancer in Poland: undergoing improvements (this issue) Ruszkowski, J.: Colorectal cancer in Poland: undergoing improvements (this issue)
38.
Zurück zum Zitat Pinto, C.G., Paquete, A.T., Pissarra, I.: Colorectal cancer in Portugal (this issue) Pinto, C.G., Paquete, A.T., Pissarra, I.: Colorectal cancer in Portugal (this issue)
39.
Zurück zum Zitat Schurer, W.: The current status of colorectal cancer in the Netherlands: directions to the future (this issue) Schurer, W.: The current status of colorectal cancer in the Netherlands: directions to the future (this issue)
40.
Zurück zum Zitat Lopez-Bastida, J., Bellas-Beceiro, B., Quintero-Carrión, E.: The challenge of colorectal cancer prevention in Spain (this issue) Lopez-Bastida, J., Bellas-Beceiro, B., Quintero-Carrión, E.: The challenge of colorectal cancer prevention in Spain (this issue)
41.
Zurück zum Zitat Boncz, I., Brodszky, V., Péntek, M., Ágoston, I., Nagy, Z., Kárpáti, K., Kriszbacher, I., Fuszek, P., Gulácsi, L.: The disease burden of colorectal cancer in Hungary (this issue) Boncz, I., Brodszky, V., Péntek, M., Ágoston, I., Nagy, Z., Kárpáti, K., Kriszbacher, I., Fuszek, P., Gulácsi, L.: The disease burden of colorectal cancer in Hungary (this issue)
42.
Zurück zum Zitat Vrangbaek, K., Nielsen, M.B.: Colorectal cancer care in Denmark: status and dilemmas (this issue) Vrangbaek, K., Nielsen, M.B.: Colorectal cancer care in Denmark: status and dilemmas (this issue)
43.
Zurück zum Zitat Canard, J.M., Debette-Gratien, M., Dumas, R., et al.: A prospective national study on colonoscopy and sigmoidoscopy in 2000 in France. Gastroenterol. Clin. Biol. 29, 17–22 (2005) Canard, J.M., Debette-Gratien, M., Dumas, R., et al.: A prospective national study on colonoscopy and sigmoidoscopy in 2000 in France. Gastroenterol. Clin. Biol. 29, 17–22 (2005)
45.
Zurück zum Zitat Terhaar sive Droste, J.S., Craanen, M.E., Kolkman, J.J., et al.: Dutch endoscopic capacity in the era of colorectal screening. Neth. J. Med. 64, 371–374 (2006) Terhaar sive Droste, J.S., Craanen, M.E., Kolkman, J.J., et al.: Dutch endoscopic capacity in the era of colorectal screening. Neth. J. Med. 64, 371–374 (2006)
46.
Zurück zum Zitat Price, J., Campbell, C., Sells, J., et al.: Impact of UK colorectal cancer screening pilot on hospital diagnostic services. J. Public Health 27, 246–253 (2005)CrossRef Price, J., Campbell, C., Sells, J., et al.: Impact of UK colorectal cancer screening pilot on hospital diagnostic services. J. Public Health 27, 246–253 (2005)CrossRef
47.
Zurück zum Zitat Weller, D., Coleman, D., Robertson, R., et al.: The UK colorectal cancer screening pilot: results of the second round of screening in England. Br. J. Cancer 97, 1601–1605 (2007)CrossRef Weller, D., Coleman, D., Robertson, R., et al.: The UK colorectal cancer screening pilot: results of the second round of screening in England. Br. J. Cancer 97, 1601–1605 (2007)CrossRef
48.
Zurück zum Zitat Fernando, S.A., Duggan, A.E., Dent, O.F., et al.: Colonoscopy capacity in selected New Shouth Wales hospitals. Med. J. Aust. 187, 249–250 (2007) Fernando, S.A., Duggan, A.E., Dent, O.F., et al.: Colonoscopy capacity in selected New Shouth Wales hospitals. Med. J. Aust. 187, 249–250 (2007)
49.
Zurück zum Zitat Bowles, C.J.A., Leicester, R., Romaya, C., et al.: A prospective study of colonoscopy practice in the UK today: are we adequately prepared for national colorectal cancer screening tomorrow? Gut 53, 277–283 (2004)CrossRef Bowles, C.J.A., Leicester, R., Romaya, C., et al.: A prospective study of colonoscopy practice in the UK today: are we adequately prepared for national colorectal cancer screening tomorrow? Gut 53, 277–283 (2004)CrossRef
50.
Zurück zum Zitat Macrae, F.A.: Providing colonoscopy services for the National Bowel Cancer Screening Program. MJA 186, 280–281 (2007) Macrae, F.A.: Providing colonoscopy services for the National Bowel Cancer Screening Program. MJA 186, 280–281 (2007)
51.
Zurück zum Zitat Shapero, T., Hoover, J., Paszat, L.F., et al.: Colorectal cancer screening with nurse-performed flexible sigmoidoscopy: results from a Canadian community-based program. Gastrointest. Endosc. 65, 640–645 (2007)CrossRef Shapero, T., Hoover, J., Paszat, L.F., et al.: Colorectal cancer screening with nurse-performed flexible sigmoidoscopy: results from a Canadian community-based program. Gastrointest. Endosc. 65, 640–645 (2007)CrossRef
52.
Zurück zum Zitat Coebergh, J.W.W.: Challenges and pit-falls of mass screening in the European Union. Eur. J. Cancer 36, 1469–1472 (2000)CrossRef Coebergh, J.W.W.: Challenges and pit-falls of mass screening in the European Union. Eur. J. Cancer 36, 1469–1472 (2000)CrossRef
53.
Zurück zum Zitat Coebergh, J.W.W.: Colorectal cancer screening in Europe: first things first. Eur. J. Cancer 40, 638–642 (2004)CrossRef Coebergh, J.W.W.: Colorectal cancer screening in Europe: first things first. Eur. J. Cancer 40, 638–642 (2004)CrossRef
68.
Zurück zum Zitat European Society Medical Oncology Working Group: Colon cancer: ESMO clinical recommendations for diagnosis adjuvant treatment and follow-up. Ann. Oncol. 18(S2), ii21–22 (2007) European Society Medical Oncology Working Group: Colon cancer: ESMO clinical recommendations for diagnosis adjuvant treatment and follow-up. Ann. Oncol. 18(S2), ii21–22 (2007)
70.
Zurück zum Zitat European Society Medical Oncology Working Group: Advanced colorectal cancer: ESMO clinical recommendations for diagnosis, treatment and follow-up. Ann. Oncol. 18(S2), ii25–26 (2007) European Society Medical Oncology Working Group: Advanced colorectal cancer: ESMO clinical recommendations for diagnosis, treatment and follow-up. Ann. Oncol. 18(S2), ii25–26 (2007)
71.
Zurück zum Zitat European Society Medical Oncology Working Group: Rectal cancer: ESMO clinical recommendations for diagnosis, treatment and follow-up. Ann. Oncol. 18(S2), ii23–24 (2007) European Society Medical Oncology Working Group: Rectal cancer: ESMO clinical recommendations for diagnosis, treatment and follow-up. Ann. Oncol. 18(S2), ii23–24 (2007)
72.
73.
74.
Zurück zum Zitat National Comprehensive Cancer Network: Colon and rectal cancer: treatment guidelines for patients. Version V (2007) National Comprehensive Cancer Network: Colon and rectal cancer: treatment guidelines for patients. Version V (2007)
75.
Zurück zum Zitat Bisschops, R., Wilmer, A., Tack, J.: A survey on gastroenterology training in Europe. Gut 50, 724–729 (2002)CrossRef Bisschops, R., Wilmer, A., Tack, J.: A survey on gastroenterology training in Europe. Gut 50, 724–729 (2002)CrossRef
76.
Zurück zum Zitat Rivera, P., Delorg, J.P., Grosclaude, P., et al.: French medical demography in oncology: demographic futurology for the next 30 years. Bull. Cancer 91, 271–277 (2004) Rivera, P., Delorg, J.P., Grosclaude, P., et al.: French medical demography in oncology: demographic futurology for the next 30 years. Bull. Cancer 91, 271–277 (2004)
77.
Zurück zum Zitat Ruiter, D.J., Roald, B., Underwood, J., et al.: Histopathology training in Europe: a lesson for other specialties? Virchows Arch. 444, 278–282 (2004)CrossRef Ruiter, D.J., Roald, B., Underwood, J., et al.: Histopathology training in Europe: a lesson for other specialties? Virchows Arch. 444, 278–282 (2004)CrossRef
79.
Zurück zum Zitat Ciccolallo, L., Capocaccia, R., Coleman, M.P., et al.: Survival differences between European and US patients with colorectal cancer: role of stage at diagnosis. Gut 54, 268–273 (2005)CrossRef Ciccolallo, L., Capocaccia, R., Coleman, M.P., et al.: Survival differences between European and US patients with colorectal cancer: role of stage at diagnosis. Gut 54, 268–273 (2005)CrossRef
80.
Zurück zum Zitat Bouhier, K., Maurel, J., Lefevre, H., et al.: Changing practices for diagnosis and treatment of colorectal cancer in Calvados: 1990–1999. Gastroenterol. Clin. Biol. 28, 371–376 (2004)CrossRef Bouhier, K., Maurel, J., Lefevre, H., et al.: Changing practices for diagnosis and treatment of colorectal cancer in Calvados: 1990–1999. Gastroenterol. Clin. Biol. 28, 371–376 (2004)CrossRef
81.
Zurück zum Zitat de Leon, M.P., Pezzi, A., Benatti, P., et al.: Survival, surgical management and perioperative mortality of colorectal cancer in the 21-year experience of a specialised registry. Int. J. Colorectal Dis. 24, 777–788 (2009)CrossRef de Leon, M.P., Pezzi, A., Benatti, P., et al.: Survival, surgical management and perioperative mortality of colorectal cancer in the 21-year experience of a specialised registry. Int. J. Colorectal Dis. 24, 777–788 (2009)CrossRef
82.
Zurück zum Zitat Manfredi, S., Benhamiche, A.M., Meny, B., et al.: Population-based study of factors influencing occurrence and prognosis of local recurrence after surgery for rectal cancer. Br. J. Surg. 88, 1221–1227 (2001)CrossRef Manfredi, S., Benhamiche, A.M., Meny, B., et al.: Population-based study of factors influencing occurrence and prognosis of local recurrence after surgery for rectal cancer. Br. J. Surg. 88, 1221–1227 (2001)CrossRef
83.
Zurück zum Zitat Evans, H.S., Moller, H., Robinson, D., et al.: The risk of subsequent primary cancers after colorectal cancer in southeast England. Gut 50, 647–652 (2002)CrossRef Evans, H.S., Moller, H., Robinson, D., et al.: The risk of subsequent primary cancers after colorectal cancer in southeast England. Gut 50, 647–652 (2002)CrossRef
84.
Zurück zum Zitat Bouvier, A.M., Latournierie, M., Jooste, V., et al.: The lifelong risk of metachronous colorectal cancer justifies long-term colonoscopic follow-up. Eur. J. Cancer 44, 522–527 (2008)CrossRef Bouvier, A.M., Latournierie, M., Jooste, V., et al.: The lifelong risk of metachronous colorectal cancer justifies long-term colonoscopic follow-up. Eur. J. Cancer 44, 522–527 (2008)CrossRef
85.
Zurück zum Zitat Guyot, F., Faivre, J., Manfredi, S., et al.: Time trends in the treatment and survival of recurrences from colorectal cancer. Ann. Oncol. 16, 756–761 (2005)CrossRef Guyot, F., Faivre, J., Manfredi, S., et al.: Time trends in the treatment and survival of recurrences from colorectal cancer. Ann. Oncol. 16, 756–761 (2005)CrossRef
86.
Zurück zum Zitat Clerc, L., Jooste, V., Lejeune, C., et al.: Cost of care of colorectal cancers according to health care patterns and stage at diagnosis in France. Eur. J. Health Econ. (2007) Clerc, L., Jooste, V., Lejeune, C., et al.: Cost of care of colorectal cancers according to health care patterns and stage at diagnosis in France. Eur. J. Health Econ. (2007)
Metadaten
Titel
The dynamics of colorectal cancer management in 17 countries
verfasst von
Panos Kanavos
Willemien Schurer
Publikationsdatum
01.01.2010
Verlag
Springer-Verlag
Erschienen in
The European Journal of Health Economics / Ausgabe Sonderheft 1/2010
Print ISSN: 1618-7598
Elektronische ISSN: 1618-7601
DOI
https://doi.org/10.1007/s10198-009-0201-2

Weitere Artikel der Sonderheft 1/2010

The European Journal of Health Economics 1/2010 Zur Ausgabe