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Japanese Journal of Ophthalmology

Erschienen in:

01.05.2013 | Clinical Investigation

Positive correlation between the degree of visual field defect and optic radiation damage in glaucoma patients

verfasst von: Hideki Murai, Yukihisa Suzuki, Motohiro Kiyosawa, Aya M. Tokumaru, Kenji Ishii, Manabu Mochizuki

Erschienen in: Japanese Journal of Ophthalmology | Ausgabe 3/2013

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Abstract

Purpose

We evaluated optic radiation (OR) damage in patients with glaucoma by using fractional anisotropy (FA) of diffusion-tensor magnetic resonance imaging.

Methods

We studied 29 patients with glaucoma and 19 healthy controls. Regions of interest were placed over the bilateral anterior and posterior ORs on the FA maps, and the FA value of each region was measured.

Results

FA values of the bilateral anterior and posterior ORs were significantly lower in patients with glaucoma (anterior right, P = 0.0002; anterior left, P = 0.00028; posterior right, P = 0.0004; and posterior left, P = 0.0001) than in the healthy controls. In glaucoma patients, significant correlations were observed between the FA values and the average of the total deviation of the contralateral hemifields of both eyes (left hemifield and anterior right OR, correlation coefficient [r] = 0.46 [P = 0.013]; right hemifield and anterior left OR, r = 0.43 [P = 0.021]; left hemifield and posterior right OR, r = 0.54 [P = 0.0027]; and right hemifield and posterior left OR, r = 0.46 [P = 0.012]).

Conclusions

FA values of the entire OR were decreased in glaucoma patients and correlated with the degree of visual field defect.

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Titel: Positive correlation between the degree of visual field defect and optic radiation damage in glaucoma patients
verfasst von: Hideki Murai
Yukihisa Suzuki
Motohiro Kiyosawa
Aya M. Tokumaru
Kenji Ishii
Manabu Mochizuki
Publikationsdatum: 01.05.2013
Verlag: Springer Japan
Erschienen in: Japanese Journal of Ophthalmology / Ausgabe 3/2013
Print ISSN: 0021-5155
Elektronische ISSN: 1613-2246
DOI: https://doi.org/10.1007/s10384-013-0233-0

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Positive correlation between the degree of visual field defect and optic radiation damage in glaucoma patients

Abstract

Purpose

Methods

Results

Conclusions

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Ophthalmika in der Schwangerschaft

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Springer Medizin

Abstract

Purpose

Methods

Results

Conclusions

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