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Erschienen in: Japanese Journal of Ophthalmology 3/2016

28.03.2016 | Clinical Investigation

Discrepancies in assessing anterior chamber activity among uveitis specialists

verfasst von: Tun Hang Yeo, Siddharthan Ilangovan, Pearse A. Keane, Carlos Pavesio, Rupesh Agrawal

Erschienen in: Japanese Journal of Ophthalmology | Ausgabe 3/2016

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Abstract

Purpose

To evaluate current practices in anterior chamber (AC) inflammation assessment among uveitis specialists.

Methods

Uveitis specialists were invited to participate in an electronic survey designed to understand their practice in assessing AC inflammation.

Results

Sixty-five ophthalmologists participated in the survey. Of them, 69.2 % (n = 45) reported using the current Standardization of Uveitis Nomenclature (SUN) guidelines of a 1 × 1-mm slit beam when grading AC cells. Only 38.5 % (n = 5) reported routinely counting the number of cells. In the management of uveitis, 98.5 % (n = 64) valued flare assessment, but 84.6 % (n = 55) did not use laser flare photometry. In total, 36.9 % (n = 24) agreed that laser flare photometry would change their management, while 16.9 % (n = 11) did not see its usefulness. The remaining participants were undecided.

Conclusion

A number of issues limit the clinical assessment of AC inflammation. Different classifications are still being used despite efforts to standardize practice. While the value of flare is widely recognized, the role of laser flare photometry remains controversial.
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Literatur
1.
Zurück zum Zitat Hogan MJ, Kimura SJ, Thygeson P. Signs and symptoms of uveitis: I. Anterior uveitis. Am J Ophthalmol. 1964;47:155–70.CrossRef Hogan MJ, Kimura SJ, Thygeson P. Signs and symptoms of uveitis: I. Anterior uveitis. Am J Ophthalmol. 1964;47:155–70.CrossRef
2.
Zurück zum Zitat Schlaegel T. Essentials of uveitis. Boston: Little, Brown, & Company; 1967. Schlaegel T. Essentials of uveitis. Boston: Little, Brown, & Company; 1967.
3.
Zurück zum Zitat Nussenblatt RB, Whitcup SM. Uveitis: fundamentals and clinical practice. 3rd ed. Philadelphia: Mosby; 2004. Nussenblatt RB, Whitcup SM. Uveitis: fundamentals and clinical practice. 3rd ed. Philadelphia: Mosby; 2004.
4.
Zurück zum Zitat Foster CS, Vitale AT. Diagnosis and treatment of uveitis. Philadelphia: W.B. Saunders Company; 2002. Foster CS, Vitale AT. Diagnosis and treatment of uveitis. Philadelphia: W.B. Saunders Company; 2002.
5.
Zurück zum Zitat Jabs DA, Nussenblatt RB, Rosenbaum JT. Standardization of Uveitis Nomenclature Working Group. Standardization of uveitis nomenclature for reporting clinical data: results of the first international workshop. Am J Ophthalmol. 2005;140:509–16.CrossRefPubMed Jabs DA, Nussenblatt RB, Rosenbaum JT. Standardization of Uveitis Nomenclature Working Group. Standardization of uveitis nomenclature for reporting clinical data: results of the first international workshop. Am J Ophthalmol. 2005;140:509–16.CrossRefPubMed
6.
Zurück zum Zitat Herbort Carl P. Appraisal, work-up and diagnosis of anterior uveitis: a practical approach. Middle East Afr J Ophthalmol. 2009;16:159–67.PubMedPubMedCentral Herbort Carl P. Appraisal, work-up and diagnosis of anterior uveitis: a practical approach. Middle East Afr J Ophthalmol. 2009;16:159–67.PubMedPubMedCentral
7.
Zurück zum Zitat Kanski JJ, Bowling B. Clinical ophthalmology: a systemic approach. 7th ed. Philadelphia: Elsevier; 2011. Kanski JJ, Bowling B. Clinical ophthalmology: a systemic approach. 7th ed. Philadelphia: Elsevier; 2011.
8.
Zurück zum Zitat Whitcup SM. Examination of the patient with uveitis. In: Nussenblatt RB, Whitcup SM, editors. Uveitis: fundamentals and clinical practice. 4th ed. Philadelphia: Mosby; 2010. Whitcup SM. Examination of the patient with uveitis. In: Nussenblatt RB, Whitcup SM, editors. Uveitis: fundamentals and clinical practice. 4th ed. Philadelphia: Mosby; 2010.
9.
Zurück zum Zitat Ladas JG, Wheeler NC, Morhun PJ, Rimmer SO, Holland GN. Laser flare-cell photometry: methodology and clinical applications. Surv Ophthalmol. 2005;50:27–47.CrossRefPubMed Ladas JG, Wheeler NC, Morhun PJ, Rimmer SO, Holland GN. Laser flare-cell photometry: methodology and clinical applications. Surv Ophthalmol. 2005;50:27–47.CrossRefPubMed
10.
Zurück zum Zitat Sawa M, Tsurimaki Y, Tsuru T, Shimizu H. New quantitative method to determine protein concentration and cell number in aqueous in vivo. Jpn J Ophthalmol. 1988;32:132–42.PubMed Sawa M, Tsurimaki Y, Tsuru T, Shimizu H. New quantitative method to determine protein concentration and cell number in aqueous in vivo. Jpn J Ophthalmol. 1988;32:132–42.PubMed
11.
Zurück zum Zitat Kempen JH, Ganesh SK, Sangwan VS, Rathinam SR. Interobserver agreement in grading activity and site of inflammation in eyes of patients with uveitis. Am J Ophthalmol. 2008;146:813–8.CrossRefPubMed Kempen JH, Ganesh SK, Sangwan VS, Rathinam SR. Interobserver agreement in grading activity and site of inflammation in eyes of patients with uveitis. Am J Ophthalmol. 2008;146:813–8.CrossRefPubMed
12.
Zurück zum Zitat Konstantopoulou K, Del’omo R, Morley AM, Karagiannis D, Bunce C, Pavesio C. A comparative study between clinical grading of anterior chamber flare and flare reading using the Kowa laser flare meter. Int Ophthalmol. 2012;35:629–33.CrossRefPubMed Konstantopoulou K, Del’omo R, Morley AM, Karagiannis D, Bunce C, Pavesio C. A comparative study between clinical grading of anterior chamber flare and flare reading using the Kowa laser flare meter. Int Ophthalmol. 2012;35:629–33.CrossRefPubMed
13.
Zurück zum Zitat Agrawal R, Keane PA, Singh J, Saihan J, Kontos A, Pavesio CE. Comparative analysis of anterior chamber flare grading between clinicians with different levels of experience and semi-automated laser flare photometry. Ocul Immunol Inflamm. 2014;26:1–10.CrossRef Agrawal R, Keane PA, Singh J, Saihan J, Kontos A, Pavesio CE. Comparative analysis of anterior chamber flare grading between clinicians with different levels of experience and semi-automated laser flare photometry. Ocul Immunol Inflamm. 2014;26:1–10.CrossRef
14.
15.
Zurück zum Zitat Tugal-Tutkun I, Herbort CP. Laser flare photometry: a noninvasive, objective, and quantitative method to measure intraocular inflammation. Int Ophthalmol. 2010;30:453–64.CrossRefPubMed Tugal-Tutkun I, Herbort CP. Laser flare photometry: a noninvasive, objective, and quantitative method to measure intraocular inflammation. Int Ophthalmol. 2010;30:453–64.CrossRefPubMed
16.
Zurück zum Zitat Bernasconi O, Papadia M, Herbort CP. Sensitivity of laser flare photometry compared to slit-lamp cell evaluation in monitoring anterior chamber inflammation in uveitis. Int Ophthalmol. 2010;30:495–500.CrossRefPubMed Bernasconi O, Papadia M, Herbort CP. Sensitivity of laser flare photometry compared to slit-lamp cell evaluation in monitoring anterior chamber inflammation in uveitis. Int Ophthalmol. 2010;30:495–500.CrossRefPubMed
17.
Zurück zum Zitat Fang W, Zhou H, Yang P, Huang X, Wang L, Kijlstra A. Longitudinal quantification of aqueous flare and cells in Vogt-Koyanagi-Harada disease. Br J Ophthalmol. 2008;92:182–5.CrossRefPubMed Fang W, Zhou H, Yang P, Huang X, Wang L, Kijlstra A. Longitudinal quantification of aqueous flare and cells in Vogt-Koyanagi-Harada disease. Br J Ophthalmol. 2008;92:182–5.CrossRefPubMed
18.
Zurück zum Zitat Fang W, Zhou H, Yang P, Huang X, Wang L, Kijlstra A. Aqueous flare and cells in Fuchs syndrome. Eye. 2009;23:79–84.CrossRefPubMed Fang W, Zhou H, Yang P, Huang X, Wang L, Kijlstra A. Aqueous flare and cells in Fuchs syndrome. Eye. 2009;23:79–84.CrossRefPubMed
19.
Zurück zum Zitat Guex-Crosier Y, Pittet N, Herbort CP. Sensitivity of laser flare photometry to monitor inflammation in uveitis of the posterior segment. Ophthalmology. 1995;102:613–6.CrossRefPubMed Guex-Crosier Y, Pittet N, Herbort CP. Sensitivity of laser flare photometry to monitor inflammation in uveitis of the posterior segment. Ophthalmology. 1995;102:613–6.CrossRefPubMed
Metadaten
Titel
Discrepancies in assessing anterior chamber activity among uveitis specialists
verfasst von
Tun Hang Yeo
Siddharthan Ilangovan
Pearse A. Keane
Carlos Pavesio
Rupesh Agrawal
Publikationsdatum
28.03.2016
Verlag
Springer Japan
Erschienen in
Japanese Journal of Ophthalmology / Ausgabe 3/2016
Print ISSN: 0021-5155
Elektronische ISSN: 1613-2246
DOI
https://doi.org/10.1007/s10384-016-0438-0

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