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01.07.2014 | Original Article

Salvage lymphadenectomy without esophagectomy is an option for recurrent or residual lymph nodes after definitive chemoradiotherapy for esophageal cancer

verfasst von: Satoru Matono, Hiromasa Fujita, Toshiaki Tanaka, Naoki Mori, Takeshi Nagano, Kohei Nishimura, Haruhiro Hino, Kazuo Shirouzu, Hidehiro Eto, Etsuyo Ogo, Takashi Yanagawa

Erschienen in: Esophagus | Ausgabe 3/2014

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Abstract

Purposes

The aim of this study was to determine the prognostic factors in salvage surgery following definitive chemoradiotherapy (dCRT) for esophageal cancer.

Methods

We retrospectively reviewed twenty-five patients who underwent salvage surgery from 1986 to 2011 at Kurume University Hospital.

Results

Esophagectomy was adopted for 20 patients, while lymphadenectomy alone without esophagectomy was adopted for the other 5 patients. Univariate analysis found that age, response to initial treatment, presence of residual tumor, pT after salvage surgery, and severe complications were each significantly correlated with overall survival after salvage surgery. The type of surgery (esophagectomy vs lymphadenectomy) and presence of residual tumor (R) were each determined to be an independent prognostic factor by the multivariate analysis. Namely, the prognosis after R0 resection was better than that after R1/2 resection (HR 18.050, p < 0.0001), and the prognosis after salvage lymphadenectomy was better than that after salvage esophagectomy (HR 5.091, p = 0.0086).

Conclusions

Salvage lymphadenectomy without esophagectomy is suggested to be an option for patients having recurrent or residual lymph nodes without any other recurrence or residual tumor after dCRT for esophageal cancer.

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Titel: Salvage lymphadenectomy without esophagectomy is an option for recurrent or residual lymph nodes after definitive chemoradiotherapy for esophageal cancer
verfasst von: Satoru Matono
Hiromasa Fujita
Toshiaki Tanaka
Naoki Mori
Takeshi Nagano
Kohei Nishimura
Haruhiro Hino
Kazuo Shirouzu
Hidehiro Eto
Etsuyo Ogo
Takashi Yanagawa
Publikationsdatum: 01.07.2014
Verlag: Springer Japan
Erschienen in: Esophagus / Ausgabe 3/2014
Print ISSN: 1612-9059
Elektronische ISSN: 1612-9067
DOI: https://doi.org/10.1007/s10388-014-0430-z

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Abstract

Purposes

Methods

Results

Conclusions

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