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AIDS and Behavior
Erschienen in: AIDS and Behavior 8/2013

01.10.2013 | Original Paper

A Preliminary RCT of CBT-AD for Adherence and Depression Among HIV-Positive Latinos on the U.S.-Mexico Border: The Nuevo Día Study

verfasst von: Jane M. Simoni, John S. Wiebe, John A. Sauceda, David Huh, Giselle Sanchez, Virginia Longoria, C. Andres Bedoya, Steven A. Safren

Erschienen in: AIDS and Behavior | Ausgabe 8/2013

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Abstract

We conducted a preliminary RCT among 40 HIV-positive Latinos of Mexican descent on the U.S.-Mexico border who indicated imperfect adherence and depressive symptomatology. Participants were randomly assigned to culturally adapted cognitive-behavioral therapy for adherence and depression with an alarmed pillbox or usual care. Outcomes were depressive symptoms (self-report and blind clinician ratings), adherence (self-report and electronic pillbox), and biological markers. The intervention, delivered in English and Spanish, proved feasible and acceptable. Generalized estimating equations in intent-to-treat analyses showed some effects of “moderate” to “large” size, with maintenance over time. For example, intervention (vs. control) participants demonstrated at post-intervention a greater drop in BDI scores (OR = −3.64, p = 0.05) and greater adherence according to the electronic pillbox (OR = 3.78, p = 0.03). Biological markers indicated some relative improvement for CD4 count but not VL. The promising results suggest a larger trial to determine efficacy is warranted.
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Metadaten
Titel
A Preliminary RCT of CBT-AD for Adherence and Depression Among HIV-Positive Latinos on the U.S.-Mexico Border: The Nuevo Día Study
verfasst von
Jane M. Simoni
John S. Wiebe
John A. Sauceda
David Huh
Giselle Sanchez
Virginia Longoria
C. Andres Bedoya
Steven A. Safren
Publikationsdatum
01.10.2013
Verlag
Springer US
Erschienen in
AIDS and Behavior / Ausgabe 8/2013
Print ISSN: 1090-7165
Elektronische ISSN: 1573-3254
DOI
https://doi.org/10.1007/s10461-013-0538-5

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