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Erschienen in: Breast Cancer Research and Treatment 1/2015

01.05.2015 | Review

An open letter to panels that are deciding guidelines for breast cancer screening

verfasst von: Daniel B. Kopans

Erschienen in: Breast Cancer Research and Treatment | Ausgabe 1/2015

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Abstract

Panels are presently reviewing breast cancer screening guidelines. It is critical that they understand which publications are scientifically valid, and which analyses are methodologically flawed and not valid. The scientific evidence clearly supports annual mammography screening beginning at the age of 40. The analyses that suggest that screening leads to overdiagnosis of invasive breast cancers are flawed and incorrect. There is little if any overdiagnosis of these cancers. The vast majority of breast cancers occur in women who are not at elevated risk so that excluding them from screening and only screening high risk women will deny the benefits of early detection to most women who develop breast cancer. Guidelines panels should not make decisions that exclude women from screening. Women should be provided with accurate information so that they can make informed decisions and have unimpeded access to screening if that is their preference.
Literatur
2.
Zurück zum Zitat US Preventive Services Task Force (2009) Screening for breast cancer: US Preventive Services Task Force recommendation statement. Ann Intern Med 151(10):716–726CrossRef US Preventive Services Task Force (2009) Screening for breast cancer: US Preventive Services Task Force recommendation statement. Ann Intern Med 151(10):716–726CrossRef
4.
Zurück zum Zitat Jorgensen KJ, Gotzsche PC (2009) Overdiagnosis in publicly organised mammography screening programmes: systematic review of incidence trends. BMJ 339:b2587CrossRefPubMedCentralPubMed Jorgensen KJ, Gotzsche PC (2009) Overdiagnosis in publicly organised mammography screening programmes: systematic review of incidence trends. BMJ 339:b2587CrossRefPubMedCentralPubMed
5.
Zurück zum Zitat Gotzsche PC, Jorgensen KJ, Zahl PH, Mæhlen J (2012) Why mammography screening hasn’t lived up to expectations from the randomised trials. Cancer Causes Control 23:15–21CrossRefPubMed Gotzsche PC, Jorgensen KJ, Zahl PH, Mæhlen J (2012) Why mammography screening hasn’t lived up to expectations from the randomised trials. Cancer Causes Control 23:15–21CrossRefPubMed
7.
Zurück zum Zitat Zahl PH, Maehlen J, Welch HG (2008) The natural history of invasive breast cancers detected by screening mammography. Arch Intern Med 168(21):2302–2303CrossRef Zahl PH, Maehlen J, Welch HG (2008) The natural history of invasive breast cancers detected by screening mammography. Arch Intern Med 168(21):2302–2303CrossRef
8.
Zurück zum Zitat Autier P, Boniol M, Gavin A, Vatten LJ (2011) Breast cancer mortality in neighbouring European countries with different levels of screening but similar access to treatment: trend analysis of WHO mortality database. BMJ 343:55–57CrossRef Autier P, Boniol M, Gavin A, Vatten LJ (2011) Breast cancer mortality in neighbouring European countries with different levels of screening but similar access to treatment: trend analysis of WHO mortality database. BMJ 343:55–57CrossRef
9.
Zurück zum Zitat Bleyer A, Welch HG (2012) Effect of three decades of screening mammography on breast-cancer incidence. N Engl J Med 367(21):1999–2005CrossRef Bleyer A, Welch HG (2012) Effect of three decades of screening mammography on breast-cancer incidence. N Engl J Med 367(21):1999–2005CrossRef
10.
Zurück zum Zitat Welch HG, Frankel BA (2011) Likelihood that a woman with screen-detected breast cancer has had her “life saved” by that screening. Arch Intern Med 171(22):2043–2056CrossRefPubMed Welch HG, Frankel BA (2011) Likelihood that a woman with screen-detected breast cancer has had her “life saved” by that screening. Arch Intern Med 171(22):2043–2056CrossRefPubMed
11.
Zurück zum Zitat Kalager M, Zelen M, Langmark F, Adami HO (2010) Effect of screening mammography on breast-cancer mortality in Norway. N Engl J Med 363(13):1203–1210CrossRefPubMed Kalager M, Zelen M, Langmark F, Adami HO (2010) Effect of screening mammography on breast-cancer mortality in Norway. N Engl J Med 363(13):1203–1210CrossRefPubMed
12.
Zurück zum Zitat Lynge E, Braaten T, Njor SH, Olsen AH, Kumle M, Waaseth M, Lund E (2011) Mammography -activity in Norway 1983 to 2008. Acta Oncol 50(7):1062–1067CrossRefPubMed Lynge E, Braaten T, Njor SH, Olsen AH, Kumle M, Waaseth M, Lund E (2011) Mammography -activity in Norway 1983 to 2008. Acta Oncol 50(7):1062–1067CrossRefPubMed
13.
Zurück zum Zitat Hofvind S, Ursin G, Tretli S, Sebuødegård S, Møller B (2013) Breast cancer mortality in participants of the Norwegian Breast Cancer Screening Program. Cancer 119(17):3106–3112CrossRefPubMed Hofvind S, Ursin G, Tretli S, Sebuødegård S, Møller B (2013) Breast cancer mortality in participants of the Norwegian Breast Cancer Screening Program. Cancer 119(17):3106–3112CrossRefPubMed
14.
Zurück zum Zitat Tabar L, Vitak B, Tony HH, Yen MF, Duffy SW, Smith RA (2001) Beyond randomized controlled trials: organized mammographic screening substantially reduces breast carcinoma mortality. Cancer 91:1724–1731CrossRefPubMed Tabar L, Vitak B, Tony HH, Yen MF, Duffy SW, Smith RA (2001) Beyond randomized controlled trials: organized mammographic screening substantially reduces breast carcinoma mortality. Cancer 91:1724–1731CrossRefPubMed
15.
Zurück zum Zitat Duffy SW, Tabar L, Chen H, Holmqvist M, Yen M, Abdsalah S, Epstein B, E Frodis, Ljungberg E, Hedborg-Melander C, Sundbom A, Tholin M, Wiege M, Akerlund A, Wu H, Tung T, Chiu Y, Chiu C, Huang C, Smith RA, Rosen M, Stenbeck M, Holmberg L, Akerlund A (2002) The impact of organized mammography service screening on breast carcinoma mortality in seven Swedish counties. Cancer 95:458–469CrossRefPubMed Duffy SW, Tabar L, Chen H, Holmqvist M, Yen M, Abdsalah S, Epstein B, E Frodis, Ljungberg E, Hedborg-Melander C, Sundbom A, Tholin M, Wiege M, Akerlund A, Wu H, Tung T, Chiu Y, Chiu C, Huang C, Smith RA, Rosen M, Stenbeck M, Holmberg L, Akerlund A (2002) The impact of organized mammography service screening on breast carcinoma mortality in seven Swedish counties. Cancer 95:458–469CrossRefPubMed
16.
Zurück zum Zitat Otto SJ, Fracheboud J, Looman CWN, Broeders MJM, Boer R, Hendriks JNHCL, Verbeek ALM, de Koning HJ, The National Evaluation Team for Breast Cancer Screening (2003) Initiation of population-based mammography screening in Dutch municipalities and effect on breast-cancer mortality: a systematic review. Lancet 361:411–417CrossRef Otto SJ, Fracheboud J, Looman CWN, Broeders MJM, Boer R, Hendriks JNHCL, Verbeek ALM, de Koning HJ, The National Evaluation Team for Breast Cancer Screening (2003) Initiation of population-based mammography screening in Dutch municipalities and effect on breast-cancer mortality: a systematic review. Lancet 361:411–417CrossRef
17.
Zurück zum Zitat van Schoor G, Moss SM, Otten JD, Donders R, Paap E, den Heeten GJ, Holland R, Broeders MJ, Verbeek AL (2011) Increasingly strong reduction in breast cancer mortality due to screening. Br J Cancer 104(6):910–914CrossRefPubMedCentralPubMed van Schoor G, Moss SM, Otten JD, Donders R, Paap E, den Heeten GJ, Holland R, Broeders MJ, Verbeek AL (2011) Increasingly strong reduction in breast cancer mortality due to screening. Br J Cancer 104(6):910–914CrossRefPubMedCentralPubMed
18.
Zurück zum Zitat Otto SJ, Fracheboud J, Verbeek ALM, Boer R, Reijerink-Verheij JCIY, Otten JDM, Broeders MJM, de Koning HJ, The National Evaluation Team for Breast Cancer Screening (2011) Mammography screening and risk of breast cancer death: a population-based case–control study. Cancer Epidemiol Biomark Prev. doi:10.1158/1055-9965.EPI-11-0476 Otto SJ, Fracheboud J, Verbeek ALM, Boer R, Reijerink-Verheij JCIY, Otten JDM, Broeders MJM, de Koning HJ, The National Evaluation Team for Breast Cancer Screening (2011) Mammography screening and risk of breast cancer death: a population-based case–control study. Cancer Epidemiol Biomark Prev. doi:10.​1158/​1055-9965.​EPI-11-0476
19.
Zurück zum Zitat Swedish Organised Service Screening Evaluation Group (2006) Reduction in breast cancer mortality from organized service screening with mammography: 1. Further confirmation with extended data. Cancer Epidemiol Biomark Prev 15:45–51CrossRef Swedish Organised Service Screening Evaluation Group (2006) Reduction in breast cancer mortality from organized service screening with mammography: 1. Further confirmation with extended data. Cancer Epidemiol Biomark Prev 15:45–51CrossRef
20.
Zurück zum Zitat Hellquist BN, Czene K, Hjälm A, Nyström L, Jonsson H (2015) Effectiveness of population-based service screening with mammography for women ages 40 to 49 years with a high or low risk of breast cancer: socioeconomic status, parity, and age at birth of first child. Cancer 121(2):251–258CrossRefPubMed Hellquist BN, Czene K, Hjälm A, Nyström L, Jonsson H (2015) Effectiveness of population-based service screening with mammography for women ages 40 to 49 years with a high or low risk of breast cancer: socioeconomic status, parity, and age at birth of first child. Cancer 121(2):251–258CrossRefPubMed
21.
Zurück zum Zitat Coldman A, Phillips N, Warren L, Kan L (2007) Breast cancer mortality after screening mammography in British Columbia women. Int J Cancer 120(5):1076–1080CrossRefPubMed Coldman A, Phillips N, Warren L, Kan L (2007) Breast cancer mortality after screening mammography in British Columbia women. Int J Cancer 120(5):1076–1080CrossRefPubMed
22.
Zurück zum Zitat Kopans DB (2002) Beyond randomized, controlled trials: organized mammographic screening substantially reduces breast cancer mortality. Cancer 94:580–581CrossRefPubMed Kopans DB (2002) Beyond randomized, controlled trials: organized mammographic screening substantially reduces breast cancer mortality. Cancer 94:580–581CrossRefPubMed
23.
Zurück zum Zitat Jonsson H, Bordás P, Wallin H, Nyström L, Lenner P (2007) Service screening with mammography in Northern Sweden: effects on breast cancer mortality: an update. J Med Screen 14(2):87–93CrossRefPubMed Jonsson H, Bordás P, Wallin H, Nyström L, Lenner P (2007) Service screening with mammography in Northern Sweden: effects on breast cancer mortality: an update. J Med Screen 14(2):87–93CrossRefPubMed
24.
Zurück zum Zitat Paap E, Holland R, den Heeten GJ et al (2010) A remarkable reduction of breast cancer deaths in screened versus unscreened women: a case-referent study. Cancer Causes Control 21:1569–1573CrossRefPubMed Paap E, Holland R, den Heeten GJ et al (2010) A remarkable reduction of breast cancer deaths in screened versus unscreened women: a case-referent study. Cancer Causes Control 21:1569–1573CrossRefPubMed
25.
Zurück zum Zitat Coldman A, Phillips N, Wilson C, Decker K, Chiarelli AM, Brisson J, Zhang B, Payne J, Doyle G, Ahmad R (2014) Pan-canadian study of mammography screening and mortality from breast cancer. J Natl Cancer Inst 106(11):dju261CrossRefPubMed Coldman A, Phillips N, Wilson C, Decker K, Chiarelli AM, Brisson J, Zhang B, Payne J, Doyle G, Ahmad R (2014) Pan-canadian study of mammography screening and mortality from breast cancer. J Natl Cancer Inst 106(11):dju261CrossRefPubMed
26.
Zurück zum Zitat Bleyer A, Welch HG (2012) Effect of three decades of screening mammography on breast-cancer incidence. N Engl J Med 367(21):1998–2005CrossRefPubMed Bleyer A, Welch HG (2012) Effect of three decades of screening mammography on breast-cancer incidence. N Engl J Med 367(21):1998–2005CrossRefPubMed
27.
Zurück zum Zitat Bleyer A (2014) Were our estimates of over diagnosis with mammography screening in the United States “based on faulty science”? The Oncol 19:113–126CrossRef Bleyer A (2014) Were our estimates of over diagnosis with mammography screening in the United States “based on faulty science”? The Oncol 19:113–126CrossRef
28.
Zurück zum Zitat Kopans DB (2014) Arguments against mammography screening continue to be based on faulty science. The Oncol 19:107–112CrossRef Kopans DB (2014) Arguments against mammography screening continue to be based on faulty science. The Oncol 19:107–112CrossRef
29.
Zurück zum Zitat Etzioni R, Xia J, Hubbard R, Weiss NS, Gulati R (2014) A reality check for overdiagnosis estimates associated with breast cancer screening. J Natl Cancer Inst 106(12):dju315CrossRefPubMed Etzioni R, Xia J, Hubbard R, Weiss NS, Gulati R (2014) A reality check for overdiagnosis estimates associated with breast cancer screening. J Natl Cancer Inst 106(12):dju315CrossRefPubMed
30.
Zurück zum Zitat Helvie MA, Chang JT, Hendrick RE, Banerjee M (2014) Reduction in late-stage breast cancer incidence in the mammography era: implications for overdiagnosis of invasive cancer. Cancer 120(17):2649–2656. doi:10.1002/cncr.28784 [Epub ahead of print] PubMed PMID: 24840597CrossRefPubMed Helvie MA, Chang JT, Hendrick RE, Banerjee M (2014) Reduction in late-stage breast cancer incidence in the mammography era: implications for overdiagnosis of invasive cancer. Cancer 120(17):2649–2656. doi:10.​1002/​cncr.​28784 [Epub ahead of print] PubMed PMID: 24840597CrossRefPubMed
31.
Zurück zum Zitat Puliti D, Duffy SW, Miccinesi G, de Koning H, Lynge E, Zappa M, Paci E, EUROSCREEN Working Group (2012) Overdiagnosis in mammographic screening for breast cancer in Europe: a literature review. J Med Screen 19(Suppl 1):42–56CrossRefPubMed Puliti D, Duffy SW, Miccinesi G, de Koning H, Lynge E, Zappa M, Paci E, EUROSCREEN Working Group (2012) Overdiagnosis in mammographic screening for breast cancer in Europe: a literature review. J Med Screen 19(Suppl 1):42–56CrossRefPubMed
32.
33.
Zurück zum Zitat Kopans DB (1990) The Canadian screening program: a different perspective. AJR 155:748–749CrossRef Kopans DB (1990) The Canadian screening program: a different perspective. AJR 155:748–749CrossRef
34.
Zurück zum Zitat Yaffe MJ (1993) Correction: Canada study. JNCI 85:94 Yaffe MJ (1993) Correction: Canada study. JNCI 85:94
35.
Zurück zum Zitat Bailar JC, MacMahon B (1997) Randomization in the Canadian National Breast Screening Study: a review for evidence of subversion. Can Med Assoc J 156:193–199 Bailar JC, MacMahon B (1997) Randomization in the Canadian National Breast Screening Study: a review for evidence of subversion. Can Med Assoc J 156:193–199
36.
Zurück zum Zitat Kopans DB, Feig SA (1993) The Canadian National Breast Screening Study: a critical review. AJR 161:755–760CrossRefPubMed Kopans DB, Feig SA (1993) The Canadian National Breast Screening Study: a critical review. AJR 161:755–760CrossRefPubMed
37.
Zurück zum Zitat Tarone RE (1995) The excess of patients with advanced breast cancers in young women screened with mammography in the Canadian National Breast Screening Study. Cancer 75:997–1003CrossRefPubMed Tarone RE (1995) The excess of patients with advanced breast cancers in young women screened with mammography in the Canadian National Breast Screening Study. Cancer 75:997–1003CrossRefPubMed
38.
Zurück zum Zitat Miller AB, Baines CJ, To T, Wall C (1992) Canadian National Breast Screening Study: 1. Breast cancer detection and death rates among women aged 40 to 49 years. CMAJ 147(10):1459–1476PubMedCentralPubMed Miller AB, Baines CJ, To T, Wall C (1992) Canadian National Breast Screening Study: 1. Breast cancer detection and death rates among women aged 40 to 49 years. CMAJ 147(10):1459–1476PubMedCentralPubMed
39.
Zurück zum Zitat Author of Canadian Breast Cancer Study Retracts Warnings (1992) J Natl Cancer Inst. vol 84, No. 11, 832–834 Author of Canadian Breast Cancer Study Retracts Warnings (1992) J Natl Cancer Inst. vol 84, No. 11, 832–834
40.
Zurück zum Zitat Kopans DB (2010) The 2009 US Preventive Services Task Force guidelines ignore important scientific evidence and should be revised or withdrawn. Radiology 256:15–20CrossRefPubMed Kopans DB (2010) The 2009 US Preventive Services Task Force guidelines ignore important scientific evidence and should be revised or withdrawn. Radiology 256:15–20CrossRefPubMed
41.
Zurück zum Zitat Kopans DB (2010) The 2009 US Preventive Services Task Force (USPSTF) guidelines are not supported by science: the scientific support for mammography screening. Radiol Clin N Am 48(5):843–857CrossRefPubMed Kopans DB (2010) The 2009 US Preventive Services Task Force (USPSTF) guidelines are not supported by science: the scientific support for mammography screening. Radiol Clin N Am 48(5):843–857CrossRefPubMed
42.
Zurück zum Zitat Hendrick RE, Helvie MA (2011) United States Preventive Services Task Force screening mammography recommendations: science ignored. AJR Am J Roentgenol 196(2):W112–W116 Hendrick RE, Helvie MA (2011) United States Preventive Services Task Force screening mammography recommendations: science ignored. AJR Am J Roentgenol 196(2):W112–W116
43.
Zurück zum Zitat Hendrick RE, Helvie MA (2012) Mammography screening: a new estimate of number needed to screen to prevent one breast cancer death. Am J Roentgenol 198(3):723–728CrossRef Hendrick RE, Helvie MA (2012) Mammography screening: a new estimate of number needed to screen to prevent one breast cancer death. Am J Roentgenol 198(3):723–728CrossRef
44.
Zurück zum Zitat Sprague BL, Bolton KC, Mace JL, Herschorn SD, James TA, Vacek PM, Weaver DL, Geller BM (2014) Registry-based study of trends in breast cancer screening mammography before and after the 2009 U.S. Preventive Services Task Force recommendations. Radiology 270(2):354–361 Sprague BL, Bolton KC, Mace JL, Herschorn SD, James TA, Vacek PM, Weaver DL, Geller BM (2014) Registry-based study of trends in breast cancer screening mammography before and after the 2009 U.S. Preventive Services Task Force recommendations. Radiology 270(2):354–361
45.
Zurück zum Zitat Duffy SW, Tabar L, Smith RA (2002) The mammographic screening trials: commentary on the recent work by Olsen and Gotzsche. Cancer J Clin 52:68–71CrossRef Duffy SW, Tabar L, Smith RA (2002) The mammographic screening trials: commentary on the recent work by Olsen and Gotzsche. Cancer J Clin 52:68–71CrossRef
46.
Zurück zum Zitat Hendrick RE, Smith RA, Rutledge JH, Smart CR (1997) Benefit of screening mammography in women ages 40–49: a new meta-analysis of randomized controlled trials. Monogr Natl Cancer Inst 22:87–92PubMed Hendrick RE, Smith RA, Rutledge JH, Smart CR (1997) Benefit of screening mammography in women ages 40–49: a new meta-analysis of randomized controlled trials. Monogr Natl Cancer Inst 22:87–92PubMed
47.
Zurück zum Zitat Michaelson JS, Halpern E, Kopans DB (1999) Breast cancer: computer simulation method for estimating optimal intervals for screening. Radiology 21:551–560CrossRef Michaelson JS, Halpern E, Kopans DB (1999) Breast cancer: computer simulation method for estimating optimal intervals for screening. Radiology 21:551–560CrossRef
48.
Zurück zum Zitat Mandelblatt JS, Cronin KA, Bailey S, Berry DA, de Koning HJ, Draisma G, Huang H, Lee SJ, Munsell M, Plevritis SK, Ravdin P, Schechter CB, Sigal B, Stoto MA, Stout NK, van Ravesteyn NT, Venier J, Zelen M, Feuer EJ, Breast Cancer Working Group of the Cancer Intervention and Surveillance Modeling Network (2009) Effects of mammography screening under different screening schedules: model estimates of potential benefits and harms. Ann Intern Med 151(10):738–747CrossRefPubMedCentralPubMed Mandelblatt JS, Cronin KA, Bailey S, Berry DA, de Koning HJ, Draisma G, Huang H, Lee SJ, Munsell M, Plevritis SK, Ravdin P, Schechter CB, Sigal B, Stoto MA, Stout NK, van Ravesteyn NT, Venier J, Zelen M, Feuer EJ, Breast Cancer Working Group of the Cancer Intervention and Surveillance Modeling Network (2009) Effects of mammography screening under different screening schedules: model estimates of potential benefits and harms. Ann Intern Med 151(10):738–747CrossRefPubMedCentralPubMed
49.
Zurück zum Zitat Kopans DB, Moore RH, McCarthy KA, Hall DA, Hulka C, Whitman GJ, Slanetz PJ, Halpern EF (1998) Biasing the interpretation of mammography screening data by age grouping: nothing changes abruptly at age 50. Breast J 4:139–145CrossRef Kopans DB, Moore RH, McCarthy KA, Hall DA, Hulka C, Whitman GJ, Slanetz PJ, Halpern EF (1998) Biasing the interpretation of mammography screening data by age grouping: nothing changes abruptly at age 50. Breast J 4:139–145CrossRef
50.
Zurück zum Zitat Kerlikowske K, Grady D, Barclay J, Sickles EA, Eaton A, Ernster V (1993) Positive predictive value of screening mammography by age and family history of breast cancer. JAMA 270:2444–2450CrossRefPubMed Kerlikowske K, Grady D, Barclay J, Sickles EA, Eaton A, Ernster V (1993) Positive predictive value of screening mammography by age and family history of breast cancer. JAMA 270:2444–2450CrossRefPubMed
51.
Zurück zum Zitat Kopans DB (1994) Screening for breast cancer and mortality reduction among women 40–49 years of age. Cancer 74(1 Suppl):311–322CrossRefPubMed Kopans DB (1994) Screening for breast cancer and mortality reduction among women 40–49 years of age. Cancer 74(1 Suppl):311–322CrossRefPubMed
52.
Zurück zum Zitat Tabár L, Vitak B, Chen TH, Yen AM, Cohen A, Tot T, Chiu SY, Chen SL, Fann JC, Rosell J, Fohlin H, Smith RA, Duffy SW (2011) Swedish two-county trial: impact of mammographic screening on breast cancer mortality during 3 decades. Radiology 260:658–663CrossRefPubMed Tabár L, Vitak B, Chen TH, Yen AM, Cohen A, Tot T, Chiu SY, Chen SL, Fann JC, Rosell J, Fohlin H, Smith RA, Duffy SW (2011) Swedish two-county trial: impact of mammographic screening on breast cancer mortality during 3 decades. Radiology 260:658–663CrossRefPubMed
53.
Zurück zum Zitat Seidman H, Stellman SD, Mushinski MH (1982) A different perspective on breast cancer risk factors: some implications of nonattributable risk. Cancer 32(5):301–313 Seidman H, Stellman SD, Mushinski MH (1982) A different perspective on breast cancer risk factors: some implications of nonattributable risk. Cancer 32(5):301–313
54.
Zurück zum Zitat Spivey GH, Perry BW, Clark VA (1982) Predicting the Risk of Cancer at the Time of Breast Biopsy. Am Surg 48(7):326–332PubMed Spivey GH, Perry BW, Clark VA (1982) Predicting the Risk of Cancer at the Time of Breast Biopsy. Am Surg 48(7):326–332PubMed
55.
Zurück zum Zitat Chu KC, Tarone RE, Kessler LG, Ries LA, Hankey BF, Miller BA, Edwards BK (1996) Recent trends in US breast cancer incidence, survival, and mortality rates. J Natl Cancer Inst 88(21):1571–1579CrossRefPubMed Chu KC, Tarone RE, Kessler LG, Ries LA, Hankey BF, Miller BA, Edwards BK (1996) Recent trends in US breast cancer incidence, survival, and mortality rates. J Natl Cancer Inst 88(21):1571–1579CrossRefPubMed
56.
Zurück zum Zitat Ernster VL, Barclay J, Kerliikowske K, Grady D, Henderson C (1996) Incidence of and treatment for ductal carcinoma in situ of the breast. JAMA 275:913–918CrossRefPubMed Ernster VL, Barclay J, Kerliikowske K, Grady D, Henderson C (1996) Incidence of and treatment for ductal carcinoma in situ of the breast. JAMA 275:913–918CrossRefPubMed
57.
Zurück zum Zitat Berry DA, Cronin KA, Plevritis SK, Fryback DG, Clarke L, Zelen M, Mandelblatt JS, Yakovlev AY, Habbema JD, Feuer EJ, Cancer Intervention and Surveillance Modeling Network (CISNET) Collaborators (2005) Effect of screening and adjuvant therapy on mortality from breast cancer. N Engl J Med 353:1784–1792CrossRefPubMed Berry DA, Cronin KA, Plevritis SK, Fryback DG, Clarke L, Zelen M, Mandelblatt JS, Yakovlev AY, Habbema JD, Feuer EJ, Cancer Intervention and Surveillance Modeling Network (CISNET) Collaborators (2005) Effect of screening and adjuvant therapy on mortality from breast cancer. N Engl J Med 353:1784–1792CrossRefPubMed
58.
Zurück zum Zitat Webb ML, Cady B, Michaelson JS, Bush DM, Calvillo KZ, Kopans DB, Smith BL (2014) A failure analysis of invasive breast cancer: most deaths from disease occur in women not regularly screened. Cancer 120(18):2839–2846CrossRefPubMed Webb ML, Cady B, Michaelson JS, Bush DM, Calvillo KZ, Kopans DB, Smith BL (2014) A failure analysis of invasive breast cancer: most deaths from disease occur in women not regularly screened. Cancer 120(18):2839–2846CrossRefPubMed
Metadaten
Titel
An open letter to panels that are deciding guidelines for breast cancer screening
verfasst von
Daniel B. Kopans
Publikationsdatum
01.05.2015
Verlag
Springer US
Erschienen in
Breast Cancer Research and Treatment / Ausgabe 1/2015
Print ISSN: 0167-6806
Elektronische ISSN: 1573-7217
DOI
https://doi.org/10.1007/s10549-015-3373-8

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