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Erschienen in: The International Journal of Cardiovascular Imaging 5/2018

30.11.2017 | Original Paper

Mechanical deformation in adult patients with unrepaired aortic coarctation

verfasst von: Leonel Avendaño-Pérez, María Elena Soto, Nydia Ávila-Vanzzini, Guillermo Bracamontes-Castelo, José Carlos Ruán-Díaz, Erick Alexanderson-Rosas, Nilda Espinola-Zavaleta

Erschienen in: The International Journal of Cardiovascular Imaging | Ausgabe 5/2018

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Abstract

Aortic coarctation is a congenital heart disease that causes an increased left ventricular afterload, resulting in increased systolic parietal tension, compensatory hypertrophy, and left ventricular systolic and diastolic dysfunction. The speckle tracking is a new echocardiographic technique that allows the detection of subclinic left ventricular systolic dysfunction. The aim of this study was to detect early left ventricular dysfunction using mechanical deformation by echocardiography in adults with un-repaired aortic coarctation. A total of 41 subjects were studied, 20 patients with aortic coarctation and 21 control subjects, 21 women (51.2%), with an average age of 30 ± 10 years. All patients with aortic coarctation had systemic arterial hypertension (p < 0.001). Seventy percent (14/20) of the patients had bicuspid aortic valve. Statistically significance (p < 0.005) were found in left ventricular mass index, E/e ratio, pulmonary artery systolic pressure and peak velocity and maximum gradient of the aortic valve. The global longitudinal deformation of the left ventricle in patients with aortic coarctation was significative decreased, p < 0.001. The ejection fraction and the global longitudinal deformation of the left ventricle were significantly lower in patients with aortic coarctation compared to the control group, p < 0.003, p < 0.001, respectively. The subgroup of patients with coarctation and left ventricular ejection fraction < 55% had a marked decrease in global longitudinal strain (− 15.9 ± 4%). The radial deformation was increased in patients with aortic coarctation and showed a trend to be significant (r = 0.421; p < 0.06). A significant negative correlation was observed between the global longitudinal deformation and left ventricular mass index (r = 0.54; p = 0.01) in the aortic coarctation group. The patients with aortic coarctation and left ventricular hypertrophy had marked reduction of left ventricular global longitudinal deformation (− 16%, p < 0.05). In our study patients with normal left ventricular ejection fraction had abnormal global longitudinal deformation and also the increased left ventricular mass was related with a decreased left ventricular global longitudinal deformation as a sign of subclinical systolic dysfunction.
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Metadaten
Titel
Mechanical deformation in adult patients with unrepaired aortic coarctation
verfasst von
Leonel Avendaño-Pérez
María Elena Soto
Nydia Ávila-Vanzzini
Guillermo Bracamontes-Castelo
José Carlos Ruán-Díaz
Erick Alexanderson-Rosas
Nilda Espinola-Zavaleta
Publikationsdatum
30.11.2017
Verlag
Springer Netherlands
Erschienen in
The International Journal of Cardiovascular Imaging / Ausgabe 5/2018
Print ISSN: 1569-5794
Elektronische ISSN: 1875-8312
DOI
https://doi.org/10.1007/s10554-017-1286-9

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