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Erschienen in: Digestive Diseases and Sciences 5/2010

01.05.2010 | Original Article

Clinical Outcomes After Self-Expanding Plastic Stent Placement for Refractory Benign Esophageal Strictures

verfasst von: Young S. Oh, Michael L. Kochman, Nuzhat A. Ahmad, Gregory G. Ginsberg

Erschienen in: Digestive Diseases and Sciences | Ausgabe 5/2010

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Abstract

Background

Refractory benign esophageal strictures (RBES) are defined as those that persist structurally and symptomatically after repeated dilation sessions. Small series have reported favorable outcomes after placement and subsequent removal of Polyflex™ self-expanding plastic stents (SEPS).

Aims

To characterize the outcomes after Polyflex™ stent placement in patients with RBES.

Methods

Outcomes of consecutive patients who underwent Polyflex™ stent placement for RBES between April 15, 2005 and November 20, 2006 were analyzed retrospectively. The etiology of the stricture, number of dilations prior to initial SEPS placement, size of stent placed, stricture resolution after SEPS removal, cases of stent migration, duration of SEPS placement, time to repeat dilation and/or SEPS replacement after stent removal, and complications were assessed.

Results

Twenty-three Polyflex™ stents were placed in 13 patients suitable for analysis. The majority of stenoses (11/13) were attributable to anastomotic strictures after curative esophagogastrectomy for esophageal neoplasms. All 11 patients in this group had satisfactory relief of dysphagia to solids determined clinically with indwelling SEPS placement. SEPS migration occurred in seven instances (30% of SEPS placed). Dysphagia remediation after subsequent SEPS removal was observed in only three patients (23%). Placement of a partially covered metal stent within a Polyflex™ stent was necessary in one case due to epithelial hyperplasia. The mean time for repeat dilation and/or SEPS reinsertion due to recurrent dysphagia after stent removal was 37 days (range 6–120 days).

Conclusions

Polyflex™ stents provided satisfactory palliation of dysphagia for RBES while in place. However, unplanned SEPS migration and dysphagia recurrence after stent removal were common.
Literatur
1.
Zurück zum Zitat Marks RD, Richter JE. Peptic strictures of the esophagus. Am J Gastroenterol. 1993;88:1160–1173.PubMed Marks RD, Richter JE. Peptic strictures of the esophagus. Am J Gastroenterol. 1993;88:1160–1173.PubMed
2.
Zurück zum Zitat Kochman ML, McClave SA, Boyce HW. The refractory and the recurrent esophageal stricture: a definition. Gastrointest Endosc. 2005;62:474–475.CrossRefPubMed Kochman ML, McClave SA, Boyce HW. The refractory and the recurrent esophageal stricture: a definition. Gastrointest Endosc. 2005;62:474–475.CrossRefPubMed
3.
Zurück zum Zitat Shah JN. Benign refractory esophageal strictures: widening the endoscopist’s role. Gastrointest Endosc. 2006;63:164–167.CrossRefPubMed Shah JN. Benign refractory esophageal strictures: widening the endoscopist’s role. Gastrointest Endosc. 2006;63:164–167.CrossRefPubMed
4.
Zurück zum Zitat Lee M, Kubik CM, Polhamus CD, Brady CE 3rd, Kadakia SC. Preliminary experience with endoscopic intralesional steroid injection therapy for refractory upper gastrointestinal strictures. Gastroinest Endosc. 1995;41:598–601.CrossRef Lee M, Kubik CM, Polhamus CD, Brady CE 3rd, Kadakia SC. Preliminary experience with endoscopic intralesional steroid injection therapy for refractory upper gastrointestinal strictures. Gastroinest Endosc. 1995;41:598–601.CrossRef
5.
Zurück zum Zitat Zein NN, Greseth JM, Perrault J. Endoscopic intralesional steroid injections in the management of refractory esophageal strictures. Gastrointest Endosc. 1995;41:596–598.CrossRefPubMed Zein NN, Greseth JM, Perrault J. Endoscopic intralesional steroid injections in the management of refractory esophageal strictures. Gastrointest Endosc. 1995;41:596–598.CrossRefPubMed
6.
Zurück zum Zitat Ramage JI Jr, Rumalla A, Baron TH, et al. A prospective, randomized, double-blind, placebo-controlled trial of endoscopic steroid injection therapy for recalcitrant esophageal peptic strictures. Am J Gastroenterol. 2005;100:2419–2425.CrossRefPubMed Ramage JI Jr, Rumalla A, Baron TH, et al. A prospective, randomized, double-blind, placebo-controlled trial of endoscopic steroid injection therapy for recalcitrant esophageal peptic strictures. Am J Gastroenterol. 2005;100:2419–2425.CrossRefPubMed
7.
Zurück zum Zitat Hordijk ML, Sersema PD, Tilanus HW, Kuipers EJ. Electrocautery therapy for refractory anastomotic strictures of the esophagus. Gastrointest Endosc. 2006;63:157–163.CrossRefPubMed Hordijk ML, Sersema PD, Tilanus HW, Kuipers EJ. Electrocautery therapy for refractory anastomotic strictures of the esophagus. Gastrointest Endosc. 2006;63:157–163.CrossRefPubMed
8.
Zurück zum Zitat Beilstein MC, Kochman ML. Endoscopic incision of a refractory esophageal stricture: novel management with an endoscopic scissors. Gastrointest Endosc. 2005;61:623–625.CrossRefPubMed Beilstein MC, Kochman ML. Endoscopic incision of a refractory esophageal stricture: novel management with an endoscopic scissors. Gastrointest Endosc. 2005;61:623–625.CrossRefPubMed
9.
Zurück zum Zitat Karbowski M, Schembre D, Kozarek R, Ayub K, Low D. Polyflex self-expanding, removable plastic stents: assessment of treatment efficacy and safety in a variety of benign and malignant conditions of the esophagus. Surg Endosc. 2008;22:1326–1333.CrossRefPubMed Karbowski M, Schembre D, Kozarek R, Ayub K, Low D. Polyflex self-expanding, removable plastic stents: assessment of treatment efficacy and safety in a variety of benign and malignant conditions of the esophagus. Surg Endosc. 2008;22:1326–1333.CrossRefPubMed
10.
Zurück zum Zitat Repici A, Conio M, De Angelis C, et al. Temporary placement of an expandable polyester silicone-covered stent for treatment of refractory benign esophageal stricture. Gastrointest Endosc. 2004;60:513–519.CrossRefPubMed Repici A, Conio M, De Angelis C, et al. Temporary placement of an expandable polyester silicone-covered stent for treatment of refractory benign esophageal stricture. Gastrointest Endosc. 2004;60:513–519.CrossRefPubMed
11.
Zurück zum Zitat Evrard S, Le Moine O, Lazaraki G, Dormann A, El Nakadi I, Devière J. Self-expanding plastic stents for benign esophageal lesions. Gastrointest Endosc. 2004;60:894–900.CrossRefPubMed Evrard S, Le Moine O, Lazaraki G, Dormann A, El Nakadi I, Devière J. Self-expanding plastic stents for benign esophageal lesions. Gastrointest Endosc. 2004;60:894–900.CrossRefPubMed
12.
Zurück zum Zitat Triester SL, Fleischer DE, Sharma VK. Failure of self-expanding plastic stents in treatment of refractory benign esophageal strictures. Endoscopy. 2006;38:533–537.CrossRefPubMed Triester SL, Fleischer DE, Sharma VK. Failure of self-expanding plastic stents in treatment of refractory benign esophageal strictures. Endoscopy. 2006;38:533–537.CrossRefPubMed
13.
Zurück zum Zitat Oh YS, Kochman ML. Polyflex esophageal stent migration with elimination per rectum. Gastrointest Endosc. 2007;66:633.CrossRefPubMed Oh YS, Kochman ML. Polyflex esophageal stent migration with elimination per rectum. Gastrointest Endosc. 2007;66:633.CrossRefPubMed
14.
Zurück zum Zitat Dua KS, Vleggaar FP, Santharam R, Siersema PD. Removable self-expanding plastic esophageal stent as a continuous, non-permanent dilator in treating refractory benign esophageal strictures: a prospective two-center study. Am J Gastroenterol. 2008;103:2988–2994.CrossRefPubMed Dua KS, Vleggaar FP, Santharam R, Siersema PD. Removable self-expanding plastic esophageal stent as a continuous, non-permanent dilator in treating refractory benign esophageal strictures: a prospective two-center study. Am J Gastroenterol. 2008;103:2988–2994.CrossRefPubMed
15.
Zurück zum Zitat Holm AN, a Levy JG, Gostout CJ, Topazian MD, Baron TH. Self-expanding plastic stents in the treatment of benign esophageal conditions. Gastrointest Endosc. 2008;67:20–25.CrossRefPubMed Holm AN, a Levy JG, Gostout CJ, Topazian MD, Baron TH. Self-expanding plastic stents in the treatment of benign esophageal conditions. Gastrointest Endosc. 2008;67:20–25.CrossRefPubMed
16.
Zurück zum Zitat Barthel JS, Kelley ST, Klapman JB. Management of persistent gastroesophageal anastomotic strictures with removable self-expandable polyester silicon-covered (Polyflex) stents: an alternative to serial dilation. Gastorintest Endosc. 2008;67:546–552.CrossRef Barthel JS, Kelley ST, Klapman JB. Management of persistent gastroesophageal anastomotic strictures with removable self-expandable polyester silicon-covered (Polyflex) stents: an alternative to serial dilation. Gastorintest Endosc. 2008;67:546–552.CrossRef
17.
Zurück zum Zitat Radecke K, Gerken G, Treichel U. Impact of a self-expanding, plastic esophageal stent on various esophageal stenoses, fistulas, and leakages: a single-center experience in 39 patients. Gastrointest Endosc. 2005;61:812–818.CrossRefPubMed Radecke K, Gerken G, Treichel U. Impact of a self-expanding, plastic esophageal stent on various esophageal stenoses, fistulas, and leakages: a single-center experience in 39 patients. Gastrointest Endosc. 2005;61:812–818.CrossRefPubMed
18.
Zurück zum Zitat Rogart J, Greenwald A, Rossi F, Barrett P, Aslanian H. Aortoesophageal fistula following Polyflex stent placement for refractory benign esophageal stricture. Endoscopy. 2007;39(Suppl 1):E321–E322.CrossRefPubMed Rogart J, Greenwald A, Rossi F, Barrett P, Aslanian H. Aortoesophageal fistula following Polyflex stent placement for refractory benign esophageal stricture. Endoscopy. 2007;39(Suppl 1):E321–E322.CrossRefPubMed
19.
Zurück zum Zitat Pennathur A, Chang AC, McGrath KM, et al. Polyflex expandable stents in the treatment of esophageal disease: initial experience. Ann Thorac Surg. 2008;85:1968–1973.CrossRefPubMed Pennathur A, Chang AC, McGrath KM, et al. Polyflex expandable stents in the treatment of esophageal disease: initial experience. Ann Thorac Surg. 2008;85:1968–1973.CrossRefPubMed
20.
Zurück zum Zitat Kochman ML. Removable endoprostetics in the management of esophageal pathology: all strictures and fistulae are not created equal. Gastrointest Endosc. 2008;67:26–27.CrossRefPubMed Kochman ML. Removable endoprostetics in the management of esophageal pathology: all strictures and fistulae are not created equal. Gastrointest Endosc. 2008;67:26–27.CrossRefPubMed
Metadaten
Titel
Clinical Outcomes After Self-Expanding Plastic Stent Placement for Refractory Benign Esophageal Strictures
verfasst von
Young S. Oh
Michael L. Kochman
Nuzhat A. Ahmad
Gregory G. Ginsberg
Publikationsdatum
01.05.2010
Verlag
Springer US
Erschienen in
Digestive Diseases and Sciences / Ausgabe 5/2010
Print ISSN: 0163-2116
Elektronische ISSN: 1573-2568
DOI
https://doi.org/10.1007/s10620-010-1134-4

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