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Erschienen in:
01.11.2015 | Original Article
The Feasibility of Performing Colorectal Endoscopic Submucosal Dissection Without Previous Experience in Performing Gastric Endoscopic Submucosal Dissection
Erschienen in: Digestive Diseases and Sciences | Ausgabe 11/2015
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Background
Experience in gastric endoscopic submucosal dissection (ESD) has been suggested as a prerequisite for performing colorectal ESD by some experts.
Aims
To evaluate the feasibility of performing colorectal ESD without experience in gastric ESD.
Methods
Between November 2009 and December 2013, ESD was attempted for 250 colorectal lesions by an endoscopist having extensive colonoscopy experience but no prior experience of gastric ESD. All attempts were categorized according to the chronological order of procedures: group 1, attempts 1–50; group 2, attempts 51–100; group 3, attempts 101–150; group 4, attempts 151–200; and group 5, attempts 201–250. Procedure-related outcomes were analyzed.
Results
En bloc resection rate ≥80 % was achieved after initial ten ESD attempts. The ESD success rate (72, 80, 90, 90, and 94 % in group 1–5, respectively; p for trend = 0.001), perforation rate (14, 14, 6, 6, and 0 % in group 1–5, respectively; p for trend = 0.003), and macroperforation rate (6, 6, 2, 2, and 0 % in group 1–5, respectively; p for trend = 0.042) improved as experience accumulated. Performing >100 ESDs, rectal location, and absence of submucosal fibrosis were independent predictors of successful procedure.
Conclusion
Colorectal ESD can be safely and effectively performed by an endoscopist having extensive experience in colonoscopy-related procedures even without previous experience of gastric ESD. Meticulous case selection for ESD novice and active supervision by expert endoscopists during the initial learning period may minimize the risk of perforation.