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Erschienen in: Familial Cancer 4/2011

01.12.2011

Microsatellite instability analysis in uterine cavity washings as a screening tool for endometrial cancer in Lynch syndrome

verfasst von: Julie Bouquier, Hélène Blons, Céline Narjoz, Fabrice Lécuru, Pierre Laurent-Puig, Anne-Sophie Bats

Erschienen in: Familial Cancer | Ausgabe 4/2011

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Abstract

Although patients with Lynch syndrome (LS) are at high risk of endometrial cancer, gynecologic screening has been poorly investigated and diagnostic value of current screening tests remains unclear. Microsatellite instability (MSI) phenotype is found in more than 90% of endometrial cancers developed in LS patients. Here we report the first two cases of unstable endometrial tumors with detection of MSI in uterine cavity washings cells. This new technique may be a promising screening tool in LS.
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Metadaten
Titel
Microsatellite instability analysis in uterine cavity washings as a screening tool for endometrial cancer in Lynch syndrome
verfasst von
Julie Bouquier
Hélène Blons
Céline Narjoz
Fabrice Lécuru
Pierre Laurent-Puig
Anne-Sophie Bats
Publikationsdatum
01.12.2011
Verlag
Springer Netherlands
Erschienen in
Familial Cancer / Ausgabe 4/2011
Print ISSN: 1389-9600
Elektronische ISSN: 1573-7292
DOI
https://doi.org/10.1007/s10689-011-9470-x

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