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Erschienen in: Journal of Assisted Reproduction and Genetics 8/2010

01.08.2010 | fertility preservation

Ovarian stimulation during the luteal phase for fertility preservation of cancer patients: case reports and review of the literature

verfasst von: Giuliano M. Bedoschi, Felipe Oliveira de Albuquerque, Rui Alberto Ferriani, Paula Andrea Navarro

Erschienen in: Journal of Assisted Reproduction and Genetics | Ausgabe 8/2010

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Abstract

Purpose

To report the case of a patient with a diagnosis of infiltrative ductal carcinoma of the breast (case 1) and of a patient with Hodgkin’s lymphoma (case 2), both submitted to ovarian stimulation during the luteal phase of the menstrual cycle in order to cryopreserve embryos and oocytes, respectively, in view of the need to start chemotherapy within a maximum of three weeks.

Methods

Case reports

Results

Both patients were submitted to ovarian stimulation with recombinant follicle stimulating hormone together with pituitary blockade with a GnRH antagonist during the luteal phase of the cycle. Oocyte retrieval was performed nine days after the beginning of ovarian stimulation, with 12 mature oocytes being obtained in both cases. In case 1, all mature oocytes were submitted to ICSI, with fertilization and cleavage rates of 83.3% and 70%, respectively, and with the formation of seven good quality embryos. In case 2, all of mature oocytes were cryopreserved.

Conclusions

These cases demonstrate that it is possible to obtain mature oocytes when ovarian stimulation is started in the luteal phase in situations in which there is not sufficient time for conventional stimulation.
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Metadaten
Titel
Ovarian stimulation during the luteal phase for fertility preservation of cancer patients: case reports and review of the literature
verfasst von
Giuliano M. Bedoschi
Felipe Oliveira de Albuquerque
Rui Alberto Ferriani
Paula Andrea Navarro
Publikationsdatum
01.08.2010
Verlag
Springer US
Erschienen in
Journal of Assisted Reproduction and Genetics / Ausgabe 8/2010
Print ISSN: 1058-0468
Elektronische ISSN: 1573-7330
DOI
https://doi.org/10.1007/s10815-010-9429-0

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