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Journal of Assisted Reproduction and Genetics

Erschienen in:

01.09.2012 | ASSISTED REPRODUCTION TECHNOLOGIES

Outcome of conventional IVF and ICSI on sibling oocytes in the case of isolated teratozoospermia

verfasst von: Wei Fan, Shang wei Li, Lei Li, Zhongying Huang, Qianhong Ma, Yan Wang, Zhun Xiao

Erschienen in: Journal of Assisted Reproduction and Genetics | Ausgabe 9/2012

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Abstract

Purpose

To reevaluate the effect of isolated teratozoospermia on IVF and determine if there was any therapeutic benefit to isolated teratozoospermia by ICSI, since there are no widely accepted criteria for the treatment technique about isolated teratozoospermia.

Methods

A total of 441 couples with >20 million and progressive motility >30 % sperm undergoing their first IVF/ICSI cycle were included in the study between 2008 and 2010, for whom at least 8 oocytes were retrived. Isolated teratozoospermia was diagnosed in 183 of the included couples, and the rest couples (normal sperm morphology) were studied as control. Sibling oocytes were randomized to be inseminated either by ICSI or IVF. Fertilization rate, embryo quality, pregnancy rate, implantation rate and spontaneous abortion rate were assessed.

Results

There was no difference in the percentage of eggs fertilized, implantation rate, pregnancy rate and spontaneous abortion rate between conventional IVF and ICSI regardless of the percentage of normal morphology. The day 3 embryonic morphology and rate of development were not different despite the insemination method and percentage of normal morphology.

Conclusion

Because isolated teratozoospermia did not influence the major indices of IVF and the unnecessary use of ICSI is time-consuming, costly and potential risks, couples with isolated teratozoospermia need not be subjected to ICSI.

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Titel: Outcome of conventional IVF and ICSI on sibling oocytes in the case of isolated teratozoospermia
verfasst von: Wei Fan
Shang wei Li
Lei Li
Zhongying Huang
Qianhong Ma
Yan Wang
Zhun Xiao
Publikationsdatum: 01.09.2012
Verlag: Springer US
Erschienen in: Journal of Assisted Reproduction and Genetics / Ausgabe 9/2012
Print ISSN: 1058-0468
Elektronische ISSN: 1573-7330
DOI: https://doi.org/10.1007/s10815-012-9823-x

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Outcome of conventional IVF and ICSI on sibling oocytes in the case of isolated teratozoospermia