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01.01.2012 | Laboratory Investigation - Human/Animal Tissue

The genotoxic effect of radiofrequency waves on mouse brain

verfasst von: Emin Karaca, Burak Durmaz, Huseyin Altug, Teoman Yildiz, Candan Guducu, Melis Irgi, Mehtap Gulcihan Cinar Koksal, Ferda Ozkinay, Cumhur Gunduz, Ozgur Cogulu

Erschienen in: Journal of Neuro-Oncology | Ausgabe 1/2012

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Abstract

Concerns about the health effects of radiofrequency (RF) waves have been raised because of the gradual increase in usage of cell phones, and there are scientific questions and debates about the safety of those instruments in daily life. The aim of this study is to evaluate the genotoxic effects of RF waves in an experimental brain cell culture model. Brain cell cultures of the mice were exposed to 10.715 GHz with specific absorbtion rate (SAR) 0.725 W/kG signals for 6 h in 3 days at 25°C to check for the changes in the micronucleus (MNi) assay and in the expression of 11 proapoptotic and antiapoptotic genes. It was found that MNi rate increased 11-fold and STAT3 expression decreased 7-fold in the cell cultures which were exposed to RF. Cell phones which spread RF may damage DNA and change gene expression in brain cells.

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Titel: The genotoxic effect of radiofrequency waves on mouse brain
verfasst von: Emin Karaca
Burak Durmaz
Huseyin Altug
Teoman Yildiz
Candan Guducu
Melis Irgi
Mehtap Gulcihan Cinar Koksal
Ferda Ozkinay
Cumhur Gunduz
Ozgur Cogulu
Publikationsdatum: 01.01.2012
Verlag: Springer US
Erschienen in: Journal of Neuro-Oncology / Ausgabe 1/2012
Print ISSN: 0167-594X
Elektronische ISSN: 1573-7373
DOI: https://doi.org/10.1007/s11060-011-0644-z

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