Skip to main content
Erschienen in: International Journal of Clinical Pharmacy 6/2009

01.12.2009 | Research Article

Medication review and patient counselling at discharge from the hospital by community pharmacists

verfasst von: J. G. Hugtenburg, S. D. Borgsteede, J. J. Beckeringh

Erschienen in: International Journal of Clinical Pharmacy | Ausgabe 6/2009

Einloggen, um Zugang zu erhalten

Abstract

Aims In 2001, the Association of Amsterdam Community Pharmacists adopted a programme to improve the pharmaceutical care of patients who were discharged from hospital with five or more drug prescriptions. A comprehensive protocol for pharmaceutical care at discharge (IBOM-1) was developed. The aim of the study was to evaluate the initial IBOM protocol and to study the effects of the protocol on drug therapy and patient satisfaction as well as on drug use compliance and mortality. Method A controlled intervention study involving 37 community pharmacies and 715 of their registered patients who were discharged from a hospital and using at least five prescribed drugs in the years 2001–2003. The intervention included an extensive medication review and drug counselling at the patient’s home. Main outcome measure Pharmacy intervention activities, changes in medication, discontinuation of drugs prescribed at discharge, mortality, time spent on the intervention activities, and medication cost savings were all evaluated. Patient satisfaction was measured by means of a questionnaire. Results 379 and 336 patients were enrolled in the intervention and control groups, respectively. The mean number of drugs per patient not dispensed, concomitantly dispensed, or of which the quantity was changed was higher in the intervention group than in the control group (0.70 ± 1.74 vs. 0.40 ± 1.43, 0.11 ± 0.40 vs. 0.038 ± 0.26, and 0.29 ± 1.05 vs. 0.097 ± 0.52, respectively). The mean number of drugs for which the dose or dosage form was changed was similar in both groups. Substitution of brand for generic or vice versa was greater in the intervention group. Changes resulting from a PAIS signal were similar in both groups. The mean number of drugs per patient for which contact was required with the physician or the Pharmacy Hospital Service Desk was higher in the intervention group (0.35 ± 0.51 vs. 0.16 ± 0.38). About 40% of home visits resulted in the clearing of redundant drug supplies. The IBOM-1 intervention did not influence discontinuation of drugs prescribed at discharge, nor did it influence mortality. Medication costs were slightly reduced. More patients of intervention pharmacies than of control pharmacies indicated that they were (very) satisfied with the drug counselling by their community pharmacist upon delivery of their discharge medication (87% vs. 50%; χ2 < 0.001). Conclusions Structured pharmaceutical care according to the IBOM-1 protocol led to more changes in drug therapy. Home visits resulted in the clearing of redundant home drug supplies. In addition, patients were highly satisfied with the counselling at discharge from hospital by their community pharmacist. Patient counselling at discharge from hospital by pharmacists, therefore, appears to be a meaningful pharmaceutical care activity.
Literatur
1.
Zurück zum Zitat Tam VC, Knowles SR, Cornish PL, Fine N, Marchesano R, Etchells EE. Frequency, type and clinical importance of medication history errors at admission to hospital: a systematic review. CMAJ. 2005;173:510–5.PubMed Tam VC, Knowles SR, Cornish PL, Fine N, Marchesano R, Etchells EE. Frequency, type and clinical importance of medication history errors at admission to hospital: a systematic review. CMAJ. 2005;173:510–5.PubMed
2.
Zurück zum Zitat DiMatteo MR. Variations in patients’ adherence to medical recommendations: a quantitative review of 50 years of research. Med Care. 2004;42:200–9.CrossRefPubMed DiMatteo MR. Variations in patients’ adherence to medical recommendations: a quantitative review of 50 years of research. Med Care. 2004;42:200–9.CrossRefPubMed
3.
Zurück zum Zitat Winterstein AG, Sauer BC, Hepler CD, Poole C. Preventable drug-related hospital admissions. Ann Pharmacother. 2002;36:1238–48.CrossRefPubMed Winterstein AG, Sauer BC, Hepler CD, Poole C. Preventable drug-related hospital admissions. Ann Pharmacother. 2002;36:1238–48.CrossRefPubMed
4.
Zurück zum Zitat Audit Commission. A prescription for improvement. Towards more rational prescribing in general practice. London: HMSO; 1994. Audit Commission. A prescription for improvement. Towards more rational prescribing in general practice. London: HMSO; 1994.
5.
Zurück zum Zitat Runciman WB, Roughead EE, Semple SJ, Adams RJ. Adverse drug events and medication errors in Australia. Int J Qual Health Care. 2003;15(1):i49–59.CrossRefPubMed Runciman WB, Roughead EE, Semple SJ, Adams RJ. Adverse drug events and medication errors in Australia. Int J Qual Health Care. 2003;15(1):i49–59.CrossRefPubMed
6.
Zurück zum Zitat Lundkvist J, Johnsson B. Pharmacoeconomics of adverse drug reactions. Fundam Clin Pharmacol. 2004;18:275–80.CrossRefPubMed Lundkvist J, Johnsson B. Pharmacoeconomics of adverse drug reactions. Fundam Clin Pharmacol. 2004;18:275–80.CrossRefPubMed
7.
Zurück zum Zitat Beijer HJ, de Blaey CJ. Hospitalisations caused by adverse drug reactions (ADR): a meta-analysis of observational studies. Pharm World Sci. 2002;24:46–54.CrossRefPubMed Beijer HJ, de Blaey CJ. Hospitalisations caused by adverse drug reactions (ADR): a meta-analysis of observational studies. Pharm World Sci. 2002;24:46–54.CrossRefPubMed
8.
Zurück zum Zitat Miller GC, Britt HC, Valenti L. Adverse drug events in general practice patients in Australia. MJA. 2006;184:321–4.PubMed Miller GC, Britt HC, Valenti L. Adverse drug events in general practice patients in Australia. MJA. 2006;184:321–4.PubMed
9.
Zurück zum Zitat Royal S, Smeaton L, Avery A, Hurwitz B, Sheikh A. Interventions in primary care to reduce medication related adverse events and hospital admissions: systematic review and meta-analysis. Qual Saf Health Care. 2006;15:23–31.CrossRefPubMed Royal S, Smeaton L, Avery A, Hurwitz B, Sheikh A. Interventions in primary care to reduce medication related adverse events and hospital admissions: systematic review and meta-analysis. Qual Saf Health Care. 2006;15:23–31.CrossRefPubMed
10.
Zurück zum Zitat Schnipper JL, Kirwin JL, Cotugno MC, Wahlstrom SA, Brown BA, Tarvin E, et al. Role of pharmacist counseling in preventing adverse drug events after hospitalization. Arch Intern Med. 2006;166:565–71.CrossRefPubMed Schnipper JL, Kirwin JL, Cotugno MC, Wahlstrom SA, Brown BA, Tarvin E, et al. Role of pharmacist counseling in preventing adverse drug events after hospitalization. Arch Intern Med. 2006;166:565–71.CrossRefPubMed
11.
Zurück zum Zitat Wu JY, Leung WY, Chang S, Lee B, Zee B, Tong PC, et al. Effectiveness of telephone counselling by a pharmacist in reducing mortality in patients receiving polypharmacy: randomised controlled trial. Br Med J. 2006; 333:522.CrossRef Wu JY, Leung WY, Chang S, Lee B, Zee B, Tong PC, et al. Effectiveness of telephone counselling by a pharmacist in reducing mortality in patients receiving polypharmacy: randomised controlled trial. Br Med J. 2006; 333:522.CrossRef
12.
Zurück zum Zitat Kripalani S, Jackson AT, Schnipper JL, Coleman EA. Promoting effective transitions of care at hospital discharge: a review of key issues for hospitalists. J Hosp Med. 2007;2:314–23.CrossRefPubMed Kripalani S, Jackson AT, Schnipper JL, Coleman EA. Promoting effective transitions of care at hospital discharge: a review of key issues for hospitalists. J Hosp Med. 2007;2:314–23.CrossRefPubMed
13.
Zurück zum Zitat Buurma H, De Smet PA, Egberts AC. Clinical risk management in Dutch community pharmacies: the case of drug–drug interactions. Drug Saf. 2006;29:723–32.CrossRefPubMed Buurma H, De Smet PA, Egberts AC. Clinical risk management in Dutch community pharmacies: the case of drug–drug interactions. Drug Saf. 2006;29:723–32.CrossRefPubMed
14.
Zurück zum Zitat Viktil KK, Blix HS. The impact of clinical pharmacists on drug-related problems and clinical outcomes. Basic Clin Pharmacol Toxicol. 2008;102:275–80.CrossRefPubMed Viktil KK, Blix HS. The impact of clinical pharmacists on drug-related problems and clinical outcomes. Basic Clin Pharmacol Toxicol. 2008;102:275–80.CrossRefPubMed
16.
Zurück zum Zitat Shaw J, Seal R, Pilling M. Room for review. A guide to medication review: the agenda for patients, practitioners and managers. London: Medicines Partnership; 2002. Shaw J, Seal R, Pilling M. Room for review. A guide to medication review: the agenda for patients, practitioners and managers. London: Medicines Partnership; 2002.
17.
Zurück zum Zitat Herings RMC, Leufkens HGM, Heerdink ER. Chronic pharmacotherapy continued. Utrecht: PHARMO Institute for Pharmaco-Epidemiological Research; 2002 (in Dutch). Herings RMC, Leufkens HGM, Heerdink ER. Chronic pharmacotherapy continued. Utrecht: PHARMO Institute for Pharmaco-Epidemiological Research; 2002 (in Dutch).
18.
Zurück zum Zitat Naylor MD, Brooten D, Campbell R, Jacobsen BS, Mezey MD, Pauly MV, et al. Comprehensive discharge planning and home follow-up of hospitalized elders: a randomized clinical trial. JAMA. 1999;281(7):613–20.CrossRefPubMed Naylor MD, Brooten D, Campbell R, Jacobsen BS, Mezey MD, Pauly MV, et al. Comprehensive discharge planning and home follow-up of hospitalized elders: a randomized clinical trial. JAMA. 1999;281(7):613–20.CrossRefPubMed
19.
Zurück zum Zitat Ryder M, Travers B, Ledwidge M, McDonald K. Multidisciplinary care of heart failure: what have we learned and where can we improve? Eur J Cardiovasc Nurs. 2003;2(4):247–9.CrossRefPubMed Ryder M, Travers B, Ledwidge M, McDonald K. Multidisciplinary care of heart failure: what have we learned and where can we improve? Eur J Cardiovasc Nurs. 2003;2(4):247–9.CrossRefPubMed
20.
Zurück zum Zitat Stewart S, Marley JE, Horowitz JD. Effects of a multidisciplinary, home-based intervention on unplanned readmissions and survival among patients with chronic congestive heart failure: a randomised controlled study. Lancet. 1999;354(9184):1077–83.CrossRefPubMed Stewart S, Marley JE, Horowitz JD. Effects of a multidisciplinary, home-based intervention on unplanned readmissions and survival among patients with chronic congestive heart failure: a randomised controlled study. Lancet. 1999;354(9184):1077–83.CrossRefPubMed
21.
Zurück zum Zitat Nazareth I, Burton A, Shulman S, Smith P, Haines A, Timberal H. A pharmacy discharge plan for hospitalized elderly patients—a randomized controlled trial. Age Ageing. 2001;1:33–40.CrossRef Nazareth I, Burton A, Shulman S, Smith P, Haines A, Timberal H. A pharmacy discharge plan for hospitalized elderly patients—a randomized controlled trial. Age Ageing. 2001;1:33–40.CrossRef
22.
Zurück zum Zitat Holland R, Lenaghan E, Harvey I, Smith R, Shepstone L, Lipp A, et al. Does home-based medication review keep older people out of hospital? The HOMER randomised controlled trial. Br Med J. 2005;330(7486):293.CrossRef Holland R, Lenaghan E, Harvey I, Smith R, Shepstone L, Lipp A, et al. Does home-based medication review keep older people out of hospital? The HOMER randomised controlled trial. Br Med J. 2005;330(7486):293.CrossRef
23.
Zurück zum Zitat Lenaghan E, Holland R, Brooks A. Home-based medication review in a high risk elderly population in primary care—the POLYMED randomised controlled trial. Age Ageing. 2007;36:292–7.CrossRefPubMed Lenaghan E, Holland R, Brooks A. Home-based medication review in a high risk elderly population in primary care—the POLYMED randomised controlled trial. Age Ageing. 2007;36:292–7.CrossRefPubMed
Metadaten
Titel
Medication review and patient counselling at discharge from the hospital by community pharmacists
verfasst von
J. G. Hugtenburg
S. D. Borgsteede
J. J. Beckeringh
Publikationsdatum
01.12.2009
Verlag
Springer Netherlands
Erschienen in
International Journal of Clinical Pharmacy / Ausgabe 6/2009
Print ISSN: 2210-7703
Elektronische ISSN: 2210-7711
DOI
https://doi.org/10.1007/s11096-009-9314-z

Weitere Artikel der Ausgabe 6/2009

International Journal of Clinical Pharmacy 6/2009 Zur Ausgabe

Leitlinien kompakt für die Innere Medizin

Mit medbee Pocketcards sicher entscheiden.

Seit 2022 gehört die medbee GmbH zum Springer Medizin Verlag

Notfall-TEP der Hüfte ist auch bei 90-Jährigen machbar

26.04.2024 Hüft-TEP Nachrichten

Ob bei einer Notfalloperation nach Schenkelhalsfraktur eine Hemiarthroplastik oder eine totale Endoprothese (TEP) eingebaut wird, sollte nicht allein vom Alter der Patientinnen und Patienten abhängen. Auch über 90-Jährige können von der TEP profitieren.

Niedriger diastolischer Blutdruck erhöht Risiko für schwere kardiovaskuläre Komplikationen

25.04.2024 Hypotonie Nachrichten

Wenn unter einer medikamentösen Hochdrucktherapie der diastolische Blutdruck in den Keller geht, steigt das Risiko für schwere kardiovaskuläre Ereignisse: Darauf deutet eine Sekundäranalyse der SPRINT-Studie hin.

Bei schweren Reaktionen auf Insektenstiche empfiehlt sich eine spezifische Immuntherapie

Insektenstiche sind bei Erwachsenen die häufigsten Auslöser einer Anaphylaxie. Einen wirksamen Schutz vor schweren anaphylaktischen Reaktionen bietet die allergenspezifische Immuntherapie. Jedoch kommt sie noch viel zu selten zum Einsatz.

Therapiestart mit Blutdrucksenkern erhöht Frakturrisiko

25.04.2024 Hypertonie Nachrichten

Beginnen ältere Männer im Pflegeheim eine Antihypertensiva-Therapie, dann ist die Frakturrate in den folgenden 30 Tagen mehr als verdoppelt. Besonders häufig stürzen Demenzkranke und Männer, die erstmals Blutdrucksenker nehmen. Dafür spricht eine Analyse unter US-Veteranen.

Update Innere Medizin

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.