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International Urology and Nephrology

Erschienen in:

01.03.2010 | Nephrology - Review

Acute kidney injury in the elderly population

verfasst von: Rahmi Yılmaz, Yunus Erdem

Erschienen in: International Urology and Nephrology | Ausgabe 1/2010

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Abstract

The elderly population is more prone to acute kidney injury (AKI) than younger populations. Older patients have less renal reserve because of reduced glomerular filtration rates due to anatomic/functional changes, and concomitant diseases such as hypertension, diabetes, atherosclerosis, heart failure, ischemic renal disease, and obstructive uropathy. The risk of AKI may also increase as a result of aggressive diagnostic and therapeutic procedures, which include medical agents, radiology, and surgical intervention. AKI in the elderly has a multifactorial physiopathology due to different etiologies. Studies that have specifically compared prognosis of AKI in elderly versus young over the recent years suggest that age is a predictor of long-term outcome. In most cases, the treatment of AKI is similar for all age groups. The majority of critically ill patients with AKI will eventually need renal replacement therapy (RRT). The influence of RRT on renal outcome remains a subject of intense investigation and debate. Avoiding situations that could damage the kidney is an important strategy to prevent AKI development in the elderly, besides medical and interventional therapeutics.

Akposso K, Hertig A, Couprie R et al (2000) Acute renal failure in patients over 80 years old: 25 years experience. Intensive Care Med 26:400–406PubMed

Fliser D, Ritz E, Franek E (1995) Renal reserve in the elderly. Semin Nephrol 15:463–467PubMed

Musso CG, Liakopoulos V, Ioannidis I et al (2006) Acute renal failure in the elderly: particular characteristics. Int Urol Nephrol 38:787–793PubMed

Bellomo R, Kellum J, Ronco C (2001) Acute renal failure: time for consensus. Intensive Care Med 27:1685–1688PubMed

Kellum JA, Mehta RL, Ronco C (2001) Acute Dialysis Quality Initiative (ADQI). Contrib Nephrol 132:258–265PubMed

Bellomo R, Ronco C, Kellum JA et al (2004) Acute renal failure—definition, outcome measures, animal models, fluid therapy and information technology needs: the Second International Consensus Conference of the Acute Dialysis Quality Initiative (ADQI) Group. Crit Care 8:R204–R210PubMed

Kellum JA, Bellomo R, Ronco C (2008) Definition and classification of acute kidney injury. Nephron Clin Pract 109:c182–c187PubMed

Prescott GJ, Metcalfe W, Baharani J et al (2007) A prospective national study of acute renal failure treated with RRT: incidence, aetiology and outcomes. Nephrol Dial Transplant 22:2513–2519PubMed

Lameire N, Nelde A, Hoeben H et al (1999) Acute renal failure in the elderly. Geriatr Nephrol Urol 9:153–165PubMed

10.

Bellomo R (2005) Defining, quantifying, and classifying acute renal failure. Crit Care Clin 21(2):223–237PubMed

11.

Kaufman J, Dhakal M, Patel B et al (1991) Community-acquired acute renal failure. Am J Kidney Dis 17(2):191–198PubMed

12.

Feest TG, Round A, Hamad S (1993) Incidence of severe acute renal failure in adults: results of a community based study. BMJ 306:481–483PubMed

13.

Liano F, Pascual J (1996) Epidemiology of acute renal failure: a prospective, multicenter, community-based study. Madrid Acute Renal Failure Study Group. Kidney Int 50(3):811–818PubMed

14.

Nash K, Hafeez A, Hou SH (2002) Hospital-acquired renal insufficiency. Am J Kidney Dis 39(5):930–936PubMed

15.

Nolan CR, Anderson RJ (1998) Hospital-acquired acute renal failure. J Am Soc Nephrol 9(4):710–718PubMed

16.

Obialo CI, Okonofua EC, Tayade AS et al (2000) Epidemiology of de novo acute renal failure in hospitalized African Americans: comparing community-acquired vs. hospital-acquired disease. Arch Intern Med 160(9):1309–1313PubMed

17.

Wang Y, Cui Z, Fan M (2007) Hospital-acquired and community-acquired acute renal failure in hospitalized Chinese: a ten-year review. Ren Fail 29:163–168PubMed

18.

Barrantes F, Tian J, Vazquez R et al (2008) Acute kidney injury criteria predict outcomes of critically ill patients. Crit Care Med 36:1397–1403PubMed

19.

Kohli HS, Bhat A, Aravindan AN et al (2007) Predictors of mortality in elderly patients with acute renal failure in a developing country. Int Urol Nephrol 39(1):339–344PubMed

20.

Epstein M (1996) Aging and the kidney. J Am Soc Nephrol 7:1106–1122PubMed

21.

Van den Noortgate N, Janssens WH, Afschrift M et al (2001) Renal function in oldest-old on acute geriatric wards. Int Urol Nephrol 32:531–537PubMed

22.

Fliser D, Franek E, Joest M et al (1997) Renal function in elderly: impact of hypertension and cardiac function. Kidney Int 51:1196–1204PubMed

23.

Brown WW, Davis BB, Spry LA et al (1986) Aging and the kidney. Arch Intern Med 146:1790–1796PubMed

24.

Goyal VK (1982) Changes with age in the human kidney. Exp Gerontol 17:321–331PubMed

25.

Tracy RE, Berenson G, Wattigney W et al (1990) The evolution of benign arterionephrosclerosis from age 6 to 70 years. Am J Pathol 136:429–439PubMed

26.

Baert L, Steg A (1977) Is the diverticulum of the distal and collecting tubules a preliminary stage of the simple cyst in the adult? J Urol 118:707–710PubMed

27.

Musso CG (2002) Geriatric nephrology and the ‘nephrogeriatric giants’. Int Urol Nephrol 34:255–256PubMed

28.

Abrass CK, Adcox MJ, Raugi GJ (1995) Aging-associated changes in renal extracellular matrix. Am J Pathol 146:742–752PubMed

29.

Fuiano G, Sund S, Mazza G et al (2001) Renal hemodynamic response to maximal vasodilating stimulus in healthy older subjects. Kidney Int 59:1052–1058PubMed

30.

Hoang K, Tan JC, Derby G et al (2003) Determinants of glomerular hypofiltration in aging humans. Kidney Int 64:1417–1424PubMed

31.

Bäck SE, Ljungberg B, Nilsson-Ehle I et al (1989) Age dependence of renal function: clearance of iohexol and p-amino hippurate in healthy males. Scand J Clin Lab Invest 49:641–646PubMed

32.

Musso CG, Michelangelo H, Vilas M et al (2009) Creatinine reabsorption by the aged kidney. Int Urol Nephrol 41(3):727–731PubMed

33.

Goldberg TH, Finkelstein MS (1987) Difficulties in estimating glomerular filtration rate in the elderly. Arch Intern Med 147:1430–1433PubMed

34.

Wieczorowska-Tobis K, Niemir ZI, Guzik P et al (2006) Difference in estimated GFR with two different formulas in elderly individuals. Int Urol Nephrol 38:381–385PubMed

35.

Levey AS, Bosch JP, Lewis JB et al (1999) A more accurate method to estimate glomerular filtration rate from serum creatinine: a new prediction. Modification of diet in Renal Disease Study Group. Ann Intern Med 130:461–470PubMed

36.

Tian Y, Serino R, Verbalis JG et al (2004) Down regulation of renal vasopressin V2 receptor and aquaporin-2 expression parallels age-associated defects in urine concentration. Am J Physiol Renal Physiol 287:F797–F805PubMed

37.

Johnson TM, Miller M, Pillion DJ et al (2003) Arginine vasopressin and nocturnal polyuria in older adults with frequent nighttime voiding. J Urol 170:480–484PubMed

38.

Leosco D, Ferrara N, Landino P et al (1996) Effects of age on the role of atrial natriuretic factor in renal adaptation to physiologic variations of dietary salt intake. J Am Soc Nephrol 7:1045–1051PubMed

39.

Musso CG, Reynaldi J, Vilas M et al (2009) Fractional excretion of K, Na and Cl following furosemide infusion in healthy, young and very old people. Int Urol Nephrol (published online March 2009) [Epub ahead of print]

40.

Pascual J, Liaño F (1998) Causes and prognosis of acute renal failure in very old. Madrid Acute Renal Failure Study Group. J Am Geriatr Soc 46:721–725PubMed

41.

Lameire N, Van Biessen W, Vanholder R (1999) Dialysing the patient with acute renal failure in the ICU: the emperor’s clothes? Nephrol Dial Transplant 14:2570–2573PubMed

42.

Lopez-Gomez JM, Francisco Rivera F (2008) Renal biopsy findings in acute renal failure in the cohort of patients in the Spanish Registry of Glomerulonephritis. Clin J Am Soc Nephrol 3:674–681PubMed

43.

Lameire N, Matthys E, Vanholder R et al (1987) Causes and prognosis of acute renal failure in elderly patients. Nephrol Dial Transplant 2(5):316–322PubMed

44.

Kohli HS, Bhaskaran MC, Muthukumar T et al (2000) Treatment-related acute renal failure in the elderly: a hospital-based prospective study. Nephrol Dial Transplant 15:212–217PubMed

45.

Spangler PF, Risley TR, Bilyew DD (1984) The management of dehydration and incontinence in nonambulatory geriatric patients. J Appl Behav Anal 17:397–401PubMed

46.

Weinberg AD, Pals JK, Levesque PG et al (1994) Dehydration and death during febrile episodes in the nursing home. J Am Geriatr Soc 42:968–971PubMed

47.

Jerkić M, Vojvodić S, Lopez-Novoa JM (2001) The mechanism of increased renal susceptibility to toxic substances in the elderly. Part I. The role of increased vasoconstriction. Int Urol Nephrol 32:539–547PubMed

48.

Wen YK (2009) Impact of acute kidney injury on metformin-associated lactic acidosis. Int Urol Nephrol (published online March 2009) [Epub ahead of print]

49.

Frost L, Engholm G, Johnsen S et al (2001) Incident thromboembolism in the aorta and the renal, mesenteric, pelvic, and extremity arteries after discharge from the hospital with a diagnosis of atrial fibrillation. Arch Intern Med 161:272–276PubMed

50.

Haas M, Spargo BH, Wit EJ et al (2000) Etiologies and outcome of acute renal insufficiency in older adults: a renal biopsy study of 259 cases. Am J Kidney Dis 35:433–447PubMed

51.

Uezono S, Hara S, Sato Y, Komatsu H et al (2006) Renal biopsy in elderly patients: a clinicopathological analysis. Ren Fail 28:549–555PubMed

52.

Demircin G, Delibagi A, Bek K et al (2008) A one-center experience with pediatric percutaneous renal biopsy and histopathology in Ankara, Turkey. Int Urol Nephrol (published online August 2008) [Epub ahead of print]

53.

Prakash J, Singh AK, Saxena RK, Usha (2003) Glomerular diseases in the elderly in India. Int Urol Nephrol 35:283–288PubMed

54.

Furci L, Medici G, Baraldi A et al (1993) Rapidly progressive glomerulonephritis in the elderly. Long-term results. Contrib Nephrol 105:98–101PubMed

55.

Kohli HS, Bhat A, Aravindan AN, Sud K et al (2006) Spectrum of renal failure in elderly patients. Int Urol Nephrol 38(3–4):759–765PubMed

56.

Jeffrey RF, Gardiner DS, More IA et al (1992) Crescentic glomerulonephritis: experience of a single unit over a five year period. Scott Med J 37:175–178PubMed

57.

Serra A, Romero R (2002) Vasculitis with predominantly renal involvement: influence of age on the mode of presentation. Int Urol Nephrol 34(1):151–157PubMed

58.

Chen M, Yu F, Zhang Y et al (2008) Antineutrophil cytoplasmic autoantibody-associated vasculitis in older patients. Medicine 87:203–209PubMed

59.

Pascual J, Orofino L, Liaño F et al (1990) Incidence and prognosis of acute renal failure in older patients. J Am Geriatr Soc 38:25–30PubMed

60.

Mouzopoulos G, Lasanianos N, Mouzopoulos D (2008) Acute renal failure due to rhabdomyolysis after proximal humerus fracture associated with axillary artery rupture. Int Urol Nephrol 40(3):855–858PubMed

61.

Landoni G, Bove T, Crivellari M et al (2007) Acute renal failure after isolated CABG surgery: six years of experience. Minerva Anestesiol 73:559–565PubMed

62.

Uchino S, Kellum JA, Belloma R et al (2005) Acute renal failure in critically ill patients: a multinational, multicenter study. JAMA 294:813–818PubMed

63.

Garg AX, Papaioannou A, Ferko N et al (2004) Estimating the prevalence of renal in sufficiency in seniors requiring long-term care. Kidney Int 65:649–653PubMed

64.

Gupta BK, Spinowitz BS, Charytan C et al (1993) Cholesterol crystal embolization-associated renal failure after therapy with recombinant tissue-type plasminogen activator. Am J Kidney Dis 21:659–662PubMed

65.

Perazella MA (1999) Crystal-induced acute renal failure. Am J Med 106:459–465PubMed

66.

Schmitt R, Coca S, Kanbay M et al (2008) Recovery of kidney function after acute kidney injury in the elderly: a systematic review and meta-analysis. Am J Kidney Dis 52:262–271PubMed

67.

Albright RC Jr, Smelser JM, McCarthy JT et al (2000) Patient survival and renal recovery in acute renal failure: randomized comparison of cellulose acetate and polysulfone membrane dialyzers. Mayo Clin Proc 75:1141–1147PubMed

68.

Spurney RF, Fulkerson WJ, Schwab SJ (1991) Acute renal failure in critically ill patients: prognosis for recovery of kidney function after prolonged dialysis support. Crit Care Med 19:8–11PubMed

69.

Morgera S, Kraft AK, Siebert G et al (2002) Long-term outcomes in acute renal failure patients treated with continuous renal replacement therapies. Am J Kidney Dis 40:275–279PubMed

70.

Manns B, Doig CJ, Lee H et al (2003) Cost of acute renal failure requiring dialysis in the intensive care unit: clinical and resource implications of renal recovery. Crit Care Med 31:449–455PubMed

71.

Korkeila M, Ruokonen E, Takala J (2000) Costs of care, long-term prognosis and quality of life in patients requiring renal replacement therapy during intensive care. Intensive Care Med 26:1824–1831PubMed

72.

Schiffl H (2006) Renal recovery from acute tubular necrosis requiring renal replacement therapy: a prospective study in critically ill patients. Nephrol Dial Transplant 21:1248–1252PubMed

73.

Schiffl H, Fischer R (2008) Five-year outcomes of severe acute kidney injury requiring renal replacement therapy. Nephrol Dial Transplant 23:2235–2241PubMed

74.

Bagshaw SM, Laupland KB, Doig CJ et al (2005) Prognosis for long-term survival and renal recovery in critically ill patients with severe acute renal failure: a population-based study. Crit Care 9:700–709

75.

Mahajan S, Tiwari S, Bhowmik D et al (2006) Factors affecting the outcome of acute renal failure among the elderly population in India: a hospital based study. Int Urol Nephrol 38:391–396PubMed

76.

Kohli HS, Bhat A, Aravindan AN et al (2007) Predictors of mortality in elderly patients with acute renal failure in a developing country. Int Urol Nephrol 39:339–344PubMed

77.

Lima RS, Marques CN, Silva Junior GB et al (2008) Comparison between early and delayed acute kidney injury secondary to infectious disease in the intensive care unit. Int Urol Nephrol 40:731–739PubMed

78.

Santacruz F, Barreto S, Mayor MM et al (1996) Mortality in elderly patients with acute renal failure. Ren Fail 18:601–605PubMed

79.

Swartz RD, Bustami RT, Daley JM et al (2005) Estimating the impact of renal replacement therapy choice on outcome in severe acute renal failure. Clin Nephrol 63:335–345PubMed

80.

Hoste EA, Clermont G, Kersten A et al (2006) RIFLE criteria for acute kidney injury are associated with hospital mortality in critically ill patients: a cohort analysis. Crit Care 10(3):R73PubMed

81.

Coca GS, Peixoto AJ, Garg AX et al (2007) The prognostic importance of a small acute decrement in kidney function in hospitalized patients: a systematic review and meta-analysis. Am J Kidney Dis 50:712–720PubMed

82.

Bonomini V, Stefoni S, Vangelista A (1984) Long-term patient and renal prognosis in acute renal failure. Nephron 36:169–172PubMed

83.

Bagshaw SM (2006) The long-term outcome after acute renal failure. Curr Opin Crit Care 12:561–566PubMed

84.

Van Dijk PT, Mehr DR, Ooms ME et al (2005) Comorbidity and 1-year mortality risks in nursing home residents. J Am Geriatr Soc 53:660–665PubMed

85.

Gijsen R, Hoeymans N, Schellevis FG et al (2001) Causes and consequences of comorbidity: a review. J Clin Epidemiol 54:661–674PubMed

86.

Bagshaw SM (2006) Epidemiology of renal recovery after acute renal failure. Curr Opin Crit Care 12:544–550PubMed

87.

Druml W (2005) Nutritional management of acute renal failure. J Ren Nutr 15:63–70PubMed

88.

Fiaccadori E, Parenti E, Maggiore U (2008) Nutritional support in acute kidney injury. J Nephrol 21:645–656PubMed

89.

Abel RM (1983) Nutritional support in the patient with acute renal failure. J Am Coll Nutr 2:33–44PubMed

90.

Martin CM, Doig GS, Heyland DK et al (2004) Multicentre, cluster-randomized clinical trial of algorithms for critical-care enteral and parenteral therapy (ACCEPT). CMAJ 170:197–204PubMed

91.

Allen DA, Harwood S, Varagunam M et al (2003) High glucose-induced oxidative stress causes apoptosis in proximal tubular epithelial cells and is mediated by multiple caspases. FASEB J 17:908–910PubMed

92.

Augustin R, Pocar P, Wrenzycki C et al (2003) Mitogenic and antiapoptotic activity of insulin on bovine embryos produced in vitro. Reproduction 126:91–99PubMed

93.

Wan L, Bellomo R, Di Giantomasso D, Ronco C (2003) The pathogenesis of septic acute renal failure. Curr Opin Crit Care 9:496–502PubMed

94.

Van den Berghe G, Wilmer A, Hermans G et al (2006) Intensive insulin therapy in the medical ICU. N Engl J Med 354:449–461PubMed

95.

Ritchie-McLean S, Kirwan C, Levy JB (2007) Is there a role for intensive insulin therapy in patients with kidney disease. Am J Kidney Dis 50:371–378PubMed

96.

Brezis M, Agmon Y, Epstein FH (1994) Determinants of intrarenal oxygenation. I. Effects of diuretics. Am J Physiol 267(6 Pt 2):F1059–F1062PubMed

97.

Besen A, Kose F, Paydas S et al (2008) The effects of the nonsteroidal anti-inflammatory drug diclofenac sodium on the rat kidney, and alteration by furosemide. Int Urol Nephrol (published online November 2008) [Epub ahead of print]

98.

Cantarovich F, Rangoonwala B, Lorenz H et al (2004) High-dose furosemide for established ARF: a prospective, randomized, double-blind, placebo controlled, multicentre trial. Am J Kidney Dis 44:402–409PubMed

99.

Bagshaw SM, Delaney A, Haase M et al (2007) Loop diuretics in the management of acute renal failure: a systematic review and meta-analysis. Crit Care Resusc 9:60–68PubMed

100.

Mehta RL, Pascual MT, Soroko S et al (2002) Diuretics, mortality, and nonrecovery of renal function in acute renal failure. JAMA 288:2547–2553PubMed

101.

Uchino S, Doig GS, Bellomo R et al (2004) Diuretics and mortality in acute renal failure. Crit Care Med 32:1669–1677PubMed

102.

Mentzer RM Jr, Oz MC, Sladen RV et al (2007) Effects of perioperative nesiritide in patients with left ventricular dysfunction undergoing cardiac surgery the NAPA trial. J Am Coll Cardiol 49:716–726PubMed

103.

Darveau M, Notebaert E, Denault AY et al (2002) Recombinant human erythropoietin use in intensive care. Ann Pharmacother 36:1068–1074PubMed

104.

Corwin HL (2004) Erythropoietin in the critically ill: is it more than just blood? Crit Care 8:325–326PubMed

105.

Sharples EJ, Patel N, Brown P et al (2004) Erythropoietin protects the kidney against the injury and dysfunction caused by ischemia-reperfusion. J Am Soc Nephrol 15:2115–2124PubMed

106.

Johnson DW, Pat B, Vesey DA et al (2006) Delayed administration of darbepoetin or erythropoietin protects against ischemic acute renal injury and failure. Kidney Int 69:1806–1813PubMed

107.

Humes HD, Buffington DA, Lou L et al (2003) Cell therapy with a tissue-engineered kidney reduces the multiple-organ consequences of septic shock. Crit Care Med 31:2421–2428PubMed

108.

Semedo P, Wang PM, Andreucci TH et al (2007) Mesenchymal stem cells ameliorate tissue damages triggered by renal ischemia and reperfusion injury. Transplant Proc 39(2):421–423PubMed

109.

Becherucci F, Mazzinghi B, Ronconi E (2009) The role of endothelial progenitor cells in acute kidney injury. Blood Purif 27(3):261–270PubMed

110.

Jo SK, Cha DR, Cho WY et al (2002) Inflammatory cytokines and lipopolysaccharide induce fas-mediated apoptosis in renal tubular cells. Nephron 91:406–415PubMed

111.

Turgut F, Bayrak O, Catal F et al (2008) Antioxidant and protective effects of silymarin on ischemia and reperfusion injury in the kidney tissues of rats. Int Urol Nephrol 40(2):453–460PubMed

112.

Splendiani G, Mazzarella V (1996) Is the choice of membrane important for patients with acute renal failure requiring hemodialysis? Artif Organs 20:281PubMed

113.

Ronco C, Bellomo R, Homel P et al (2000) Effects of different doses in continuous veno-venous haemofiltration on outcomes of acute renal failure: a prospective randomised trial. Lancet 356:26–30PubMed

114.

Schiffl H, Lang SM, Fisher R (2002) Daily hemodialysis and the outcome of acute renal failure. N Engl J Med 346:305–310PubMed

115.

Ash SR, Bever SL (1995) Peritoneal dialysis for acute renal failure: the safe, effective, and low-cost modality. Adv Ren Replace Ther 2:160–163PubMed

116.

Ismail N, Hakim RN, Oreopoulos DG et al (1993) Renal replacement therapies in elderly: Part I. Hemodialysis and chronic peritoneal dialysis. Am J Kidney Dis 22:759–782PubMed

117.

Manji S, Shikora S, McMahon M et al (1990) Peritoneal dialysis for acute renal failure: overfeeding resulting from dextrose absorbed during dialysis. Crit Care Med 18:29–31PubMed

118.

Gabriel DP, Caramori JT, Martim LC et al (2008) High volume peritoneal dialysis vs daily hemodialysis: a randomized, controlled trial in patients with acute kidney injury. Kidney Int Suppl (108):87–93

119.

Waldrop J, Ciraulo DL, Milner TP et al (2005) A comparison of continuous renal replacement therapy to intermittent dialysis in the management of renal insufficiency in the acutely ill surgical patient. Am Surg 71:36–39PubMed

120.

Jacka MJ, Ivancinova X, Gibney RT (2005) Continuous renal replacement therapy improves renal recovery from acute renal failure. Can J Anaesth 52:327–332PubMed

121.

Mehta RL, McDonald B, Gabbai FB et al (2001) A randomized clinical trial of continuous versus intermittent dialysis for acute renal failure. Kidney Int 60:1154–1163PubMed

122.

Uehlinger DE, Jakob SM, Ferrari P et al (2005) Comparison of continuous and intermittent renal replacement therapy for acute renal failure. Nephrol Dial Transplant 20:1630–1637PubMed

123.

Augustine JJ, Sandy D, Seifert TH et al (2004) A randomized controlled trial comparing intermittent with continuous dialysis in patients with ARF. Am J Kidney Dis 44:1000–1007PubMed

124.

Rauf AA, Long KH, Gajic O et al (2008) Intermittent hemodialysis versus continuous renal replacement therapy for acute renal failure in the intensive care unit: an observational outcomes analysis. J Intensive Care Med 23:195–203PubMed

125.

Lins RL, Elseviers MM, Niepen PV et al (2009) Intermittent versus continuous renal replacement therapy for acute kidney injury patients admitted to the intensive care unit: results of a randomized clinical trial. Nephrol Dial Transplant 24(2):512–518PubMed

126.

Uchino S, Bellomo R, Kellum JA et al (2007) Patient and kidney survival by dialysis modality in critically ill patients with acute kidney injury. Int J Artif Organs 30(4):281–292PubMed

127.

Pakfetrat M, Nikoo MH, Malekmakan L et al (2009) A comparison of sodium bicarbonate infusion versus normal saline infusion and its combination with oral acetazolamide for prevention of contrast-induced nephropathy: a randomized, double-blind trial. Int Urol Nephrol 41(3):629–634PubMed

128.

Lameire N, Verbeke M, Vanholder R (1995) Prevention of clinical acute tubular necrosis with drug therapy. Nephrol Dial Transplant 10:1992–2000PubMed

129.

Lameire N, Vanholder R (2000) Drug therapy of acute renal failure. IDrugs 3:1206–1216PubMed

Titel: Acute kidney injury in the elderly population
verfasst von: Rahmi Yılmaz
Yunus Erdem
Publikationsdatum: 01.03.2010
Verlag: Springer Netherlands
Erschienen in: International Urology and Nephrology / Ausgabe 1/2010
Print ISSN: 0301-1623
Elektronische ISSN: 1573-2584
DOI: https://doi.org/10.1007/s11255-009-9629-7

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