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Hydroxychavicol: a potent xanthine oxidase inhibitor obtained from the leaves of betel, Piper betle

verfasst von: Kazuya Murata, Kikuyo Nakao, Noriko Hirata, Kensuke Namba, Takao Nomi, Yoshihisa Kitamura, Kenzo Moriyama, Takahiro Shintani, Munekazu Iinuma, Hideaki Matsuda

Erschienen in: Journal of Natural Medicines | Ausgabe 3/2009

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Abstract

The screening of Piperaceous plants for xanthine oxidase inhibitory activity revealed that the extract of the leaves of Piper betle possesses potent activity. Activity-guided purification led us to obtain hydroxychavicol as an active principle. Hydroxychavicol is a more potent xanthine oxidase inhibitor than allopurinol, which is clinically used for the treatment of hyperuricemia.

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Titel: Hydroxychavicol: a potent xanthine oxidase inhibitor obtained from the leaves of betel, Piper betle
verfasst von: Kazuya Murata
Kikuyo Nakao
Noriko Hirata
Kensuke Namba
Takao Nomi
Yoshihisa Kitamura
Kenzo Moriyama
Takahiro Shintani
Munekazu Iinuma
Hideaki Matsuda
Publikationsdatum: 01.07.2009
Verlag: Springer Japan
Erschienen in: Journal of Natural Medicines / Ausgabe 3/2009
Print ISSN: 1340-3443
Elektronische ISSN: 1861-0293
DOI: https://doi.org/10.1007/s11418-009-0331-y

Springer Medizin

Abstract

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