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Erschienen in: Obesity Surgery 6/2013

01.06.2013 | Review

Influence of Bariatric Surgery on the Use and Pharmacokinetics of Some Major Drug Classes

verfasst von: Jan Peter Yska, Susanne van der Linde, Véronique V. Tapper, Jan A. Apers, Marloes Emous, Erik R. Totté, Bob Wilffert, Eric N. van Roon

Erschienen in: Obesity Surgery | Ausgabe 6/2013

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Abstract

The purpose of this review is to evaluate the influence of bariatric surgery on the use and pharmacokinetics of some frequently used drugs. A PubMed literature search was conducted. Literature was included on influence of bariatric surgery on pharmacoepidemiology and pharmacokinetics. Drug classes to be searched for were antidepressants, antidiabetics, statins, antihypertensive agents, corticosteroids, oral contraceptives, and thyroid drugs. A reduction in the use of medication by patients after bariatric surgery has been reported for various drug classes. Very few studies have been published on the influence of bariatric surgery on the pharmacokinetics of drugs. After bariatric surgery, theoretically, reduced drug absorption may occur. Correct dosing and choosing the right dosage form for drugs used by patients after bariatric surgery are necessary for optimal pharmacotherapy. Therefore, more clinical studies are needed on the influence of bariatric surgery on the pharmacokinetics of major drugs.
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Metadaten
Titel
Influence of Bariatric Surgery on the Use and Pharmacokinetics of Some Major Drug Classes
verfasst von
Jan Peter Yska
Susanne van der Linde
Véronique V. Tapper
Jan A. Apers
Marloes Emous
Erik R. Totté
Bob Wilffert
Eric N. van Roon
Publikationsdatum
01.06.2013
Verlag
Springer-Verlag
Erschienen in
Obesity Surgery / Ausgabe 6/2013
Print ISSN: 0960-8923
Elektronische ISSN: 1708-0428
DOI
https://doi.org/10.1007/s11695-013-0882-6

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CME: 2 Punkte

Inhalte des Webinars zur S1-Leitlinie „Empfehlungen zur Therapie der akuten Appendizitis bei Erwachsenen“ sind die Darstellung des Projektes und des Erstellungswegs zur S1-Leitlinie, die Erläuterung der klinischen Relevanz der Klassifikation EAES 2015, die wissenschaftliche Begründung der wichtigsten Empfehlungen und die Darstellung stadiengerechter Therapieoptionen.

Dr. med. Mihailo Andric
Berufsverband der Deutschen Chirurgie e.V.