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Erschienen in: Current Cardiology Reports 1/2016

01.01.2016 | Nuclear Cardiology (V Dilsizian, Section Editor)

Nuclear Image-Guided Approaches for Cardiac Resynchronization Therapy (CRT)

verfasst von: Weihua Zhou, Ernest V. Garcia

Erschienen in: Current Cardiology Reports | Ausgabe 1/2016

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Abstract

Cardiac resynchronization therapy (CRT) is a standard treatment for patients with heart failure. However, 30–40 % of the patients having CRT do not respond to CRT with improved clinical symptom and cardiac functions. It is important for CRT response that left ventricular (LV) lead is placed away from scar and at or near the site of the latest mechanical activation. Nuclear image-guided approaches for CRT have shown significant clinical value to assess LV myocardial viability and mechanical dyssynchrony, recommend the optimal LV lead position, and navigate the LV lead to the target coronary venous site. All these techniques, once validated and implemented, should impact the current clinical practice.
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Literatur
1.
Zurück zum Zitat Heart disease and stroke statistics—2013 update: a report from the American Heart Association. Circulation 2013;127:e6-e245 Heart disease and stroke statistics—2013 update: a report from the American Heart Association. Circulation 2013;127:e6-e245
2.
Zurück zum Zitat McAlister FA, Ezekowitz J, Dryden DM, et al. Cardiac resynchronization therapy and implantable cardiac defibrillators in left ventricular systolic dysfunction. Evid Rep Technol Assess (Full Rep). 2007;152:1–199. McAlister FA, Ezekowitz J, Dryden DM, et al. Cardiac resynchronization therapy and implantable cardiac defibrillators in left ventricular systolic dysfunction. Evid Rep Technol Assess (Full Rep). 2007;152:1–199.
3.
Zurück zum Zitat Lozano I, Bocchiardo M, Achtelik M, et al. Impact of biventricular pacing on mortality in a randomized crossover study of patients with heart failure and ventricular arrhythmias. Pacing Clin Electrophysiol. 2000;23:1711–2.PubMedCrossRef Lozano I, Bocchiardo M, Achtelik M, et al. Impact of biventricular pacing on mortality in a randomized crossover study of patients with heart failure and ventricular arrhythmias. Pacing Clin Electrophysiol. 2000;23:1711–2.PubMedCrossRef
4.
Zurück zum Zitat Cazeau S, Leclercq C, Lavergne T, et al. Effects of multisite biventricular pacing in patients with heart failure and intraventricular conduction delay. N Engl J Med. 2001;344:873–80.PubMedCrossRef Cazeau S, Leclercq C, Lavergne T, et al. Effects of multisite biventricular pacing in patients with heart failure and intraventricular conduction delay. N Engl J Med. 2001;344:873–80.PubMedCrossRef
5.
Zurück zum Zitat Auricchio A, Stellbrink C, Sack S, et al. Long-term clinical effect of hemodynamically optimized cardiac resynchronization therapy in patients with heart failure and ventricular conduction delay. J Am Coll Cardiol. 2002;39:2026–33.PubMedCrossRef Auricchio A, Stellbrink C, Sack S, et al. Long-term clinical effect of hemodynamically optimized cardiac resynchronization therapy in patients with heart failure and ventricular conduction delay. J Am Coll Cardiol. 2002;39:2026–33.PubMedCrossRef
6.
Zurück zum Zitat Abraham WT, Fisher WG, Smith AL, et al. Cardiac resynchronization in chronic heart failure. N Engl J Med. 2002;346:1845–53.PubMedCrossRef Abraham WT, Fisher WG, Smith AL, et al. Cardiac resynchronization in chronic heart failure. N Engl J Med. 2002;346:1845–53.PubMedCrossRef
7.
Zurück zum Zitat Young JB, Abraham WT, Smith AL, et al. Combined cardiac resynchronization and implantable cardioversion defibrillation in advanced chronic heart failure: the MIRACLE ICD Trial. JAMA. 2003;289:2685–94.PubMedCrossRef Young JB, Abraham WT, Smith AL, et al. Combined cardiac resynchronization and implantable cardioversion defibrillation in advanced chronic heart failure: the MIRACLE ICD Trial. JAMA. 2003;289:2685–94.PubMedCrossRef
8.
Zurück zum Zitat Auricchio A, Stellbrink C, Butter C, et al. Clinical efficacy of cardiac resynchronization therapy using left ventricular pacing in heart failure patients stratified by severity of ventricular conduction delay. J Am Coll Cardiol. 2003;42:2109–16.PubMedCrossRef Auricchio A, Stellbrink C, Butter C, et al. Clinical efficacy of cardiac resynchronization therapy using left ventricular pacing in heart failure patients stratified by severity of ventricular conduction delay. J Am Coll Cardiol. 2003;42:2109–16.PubMedCrossRef
9.
Zurück zum Zitat Bristow MR, Saxon LA, Boehmer J, et al. Cardiac-resynchronization therapy with or without an implantable defibrillator in advanced chronic heart failure. N Engl J Med. 2004;350:2140–50.PubMedCrossRef Bristow MR, Saxon LA, Boehmer J, et al. Cardiac-resynchronization therapy with or without an implantable defibrillator in advanced chronic heart failure. N Engl J Med. 2004;350:2140–50.PubMedCrossRef
10.
Zurück zum Zitat Cleland JG, Daubert JC, Erdmann E, et al. The effect of cardiac resynchronization on morbidity and mortality in heart failure. N Engl J Med. 2005;352:1539–49.PubMedCrossRef Cleland JG, Daubert JC, Erdmann E, et al. The effect of cardiac resynchronization on morbidity and mortality in heart failure. N Engl J Med. 2005;352:1539–49.PubMedCrossRef
11.
Zurück zum Zitat 2012 ACCF/AHA/HRS focused update incorporated into the ACCF/AHA/HRS 2008 guidelines for device-based therapy of cardiac rhythm abnormalities: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines and the Heart Rhythm Society. Circulation 2013;127:e283-352 2012 ACCF/AHA/HRS focused update incorporated into the ACCF/AHA/HRS 2008 guidelines for device-based therapy of cardiac rhythm abnormalities: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines and the Heart Rhythm Society. Circulation 2013;127:e283-352
12.
Zurück zum Zitat Schuster P, Faerestrand S, Ohm O. Reverse remodeling of systolic left ventricular contraction pattern by long term cardiac resynchronization therapy: colour Doppler shows resynchronization. Heart. 2004;90:1411–6.PubMedPubMedCentralCrossRef Schuster P, Faerestrand S, Ohm O. Reverse remodeling of systolic left ventricular contraction pattern by long term cardiac resynchronization therapy: colour Doppler shows resynchronization. Heart. 2004;90:1411–6.PubMedPubMedCentralCrossRef
13.
Zurück zum Zitat Verhaert D, Grimm RA, Puntawangkoon C. Long-term reverse remodeling with cardiac resynchronization therapy: results of extended echocardiographic follow-up. J Am Coll Cardiol. 2010;55:1788–95.PubMedCrossRef Verhaert D, Grimm RA, Puntawangkoon C. Long-term reverse remodeling with cardiac resynchronization therapy: results of extended echocardiographic follow-up. J Am Coll Cardiol. 2010;55:1788–95.PubMedCrossRef
14.
Zurück zum Zitat Bax JJ, Bleeker GB, Marwick TH, et al. Left ventricular dyssynchrony predicts response and prognosis after cardiac resynchronization therapy. J Am Coll Cardiol. 2004;44:1834–40.PubMedCrossRef Bax JJ, Bleeker GB, Marwick TH, et al. Left ventricular dyssynchrony predicts response and prognosis after cardiac resynchronization therapy. J Am Coll Cardiol. 2004;44:1834–40.PubMedCrossRef
15.
Zurück zum Zitat Yu CM, Fung JW, Zhang Q, et al. Tissue Doppler imaging is superior to strain rate imaging and postsystolic shortening on the prediction of reverse remodeling in both ischemic and nonischemic heart failure after cardiac resynchronization therapy. Circulation. 2004;110:66–73.PubMedCrossRef Yu CM, Fung JW, Zhang Q, et al. Tissue Doppler imaging is superior to strain rate imaging and postsystolic shortening on the prediction of reverse remodeling in both ischemic and nonischemic heart failure after cardiac resynchronization therapy. Circulation. 2004;110:66–73.PubMedCrossRef
16.
Zurück zum Zitat Yu CM, Zhang Q, Chan YS, et al. Tissue Doppler velocity is superior to displacement and strain mapping in predicting left ventricular reverse remodeling response after cardiac resynchronization therapy. Heart. 2006;92:1452–6.PubMedPubMedCentralCrossRef Yu CM, Zhang Q, Chan YS, et al. Tissue Doppler velocity is superior to displacement and strain mapping in predicting left ventricular reverse remodeling response after cardiac resynchronization therapy. Heart. 2006;92:1452–6.PubMedPubMedCentralCrossRef
17.
Zurück zum Zitat Donal E, de Chillou C, Magnin-Poull I, Leclercq C. Imaging in cardiac resynchronization therapy: what does the clinician need? Europace. 2008;10 Suppl 3:iii70–2.PubMed Donal E, de Chillou C, Magnin-Poull I, Leclercq C. Imaging in cardiac resynchronization therapy: what does the clinician need? Europace. 2008;10 Suppl 3:iii70–2.PubMed
18.
Zurück zum Zitat Hawkins NM, Petrie MC, MacDonald MR, Hogg KJ, McMurray JJ. Selecting patients for cardiac resynchronization therapy: electrical or mechanical dyssynchrony? Eur Heart J. 2006;27:1270–81.PubMedCrossRef Hawkins NM, Petrie MC, MacDonald MR, Hogg KJ, McMurray JJ. Selecting patients for cardiac resynchronization therapy: electrical or mechanical dyssynchrony? Eur Heart J. 2006;27:1270–81.PubMedCrossRef
19.
Zurück zum Zitat Tanaka H, Nesser HJ, Buck T. Dyssynchrony by speckle-tracking echocardiography and response to cardiac resynchronization therapy: results of the Speckle Tracking and Resynchronization (STAR) study. Eur Heart J. 2010;31:1690–700.PubMedPubMedCentralCrossRef Tanaka H, Nesser HJ, Buck T. Dyssynchrony by speckle-tracking echocardiography and response to cardiac resynchronization therapy: results of the Speckle Tracking and Resynchronization (STAR) study. Eur Heart J. 2010;31:1690–700.PubMedPubMedCentralCrossRef
20.
Zurück zum Zitat Friehling M, Chen J, Saba S, et al. A prospective pilot study to evaluate the relationship between acute change in left ventricular synchrony after cardiac resynchronization therapy and patient outcome using a single-injection gated SPECT protocol. Circ Cardiovasc Imaging. 2011;4:532–9.PubMedPubMedCentralCrossRef Friehling M, Chen J, Saba S, et al. A prospective pilot study to evaluate the relationship between acute change in left ventricular synchrony after cardiac resynchronization therapy and patient outcome using a single-injection gated SPECT protocol. Circ Cardiovasc Imaging. 2011;4:532–9.PubMedPubMedCentralCrossRef
21.•
Zurück zum Zitat Auger D, Bleeker GB, Bertini M, et al. Effect of cardiac resynchronization therapy in patients without left intraventricular dyssynchrony. Eur Heart J. 2012;33:913–20. Article concludes that in patients without significant LV dyssynchrony, the induction of LV dyssynchrony after CRT may be related to a less favorable long-term outcome.PubMedPubMedCentralCrossRef Auger D, Bleeker GB, Bertini M, et al. Effect of cardiac resynchronization therapy in patients without left intraventricular dyssynchrony. Eur Heart J. 2012;33:913–20. Article concludes that in patients without significant LV dyssynchrony, the induction of LV dyssynchrony after CRT may be related to a less favorable long-term outcome.PubMedPubMedCentralCrossRef
22.
Zurück zum Zitat White JA, Yee R, Yuan X, et al. Delayed enhancement magnetic resonance imaging predicts response to cardiac resynchronization therapy in patients with intraventricular dyssynchrony. J Am Coll Cardiol. 2006;48:1953–60.PubMedCrossRef White JA, Yee R, Yuan X, et al. Delayed enhancement magnetic resonance imaging predicts response to cardiac resynchronization therapy in patients with intraventricular dyssynchrony. J Am Coll Cardiol. 2006;48:1953–60.PubMedCrossRef
23.
Zurück zum Zitat Adelstein EC, Saba S. Scar burden by myocardial perfusion imaging predicts echocardiographic response to cardiac resynchronization therapy in ischemic cardiomyopathy. Am Heart J. 2007;153:105–12.PubMedCrossRef Adelstein EC, Saba S. Scar burden by myocardial perfusion imaging predicts echocardiographic response to cardiac resynchronization therapy in ischemic cardiomyopathy. Am Heart J. 2007;153:105–12.PubMedCrossRef
24.
Zurück zum Zitat Bleeker GB, Kaandorp TA, Lamb HJ, et al. Effect of postero-lateral scar tissue on clinical and echocardiographic improvement after cardiac resynchronization therapy. Circulation. 2006;113:969–76.PubMedCrossRef Bleeker GB, Kaandorp TA, Lamb HJ, et al. Effect of postero-lateral scar tissue on clinical and echocardiographic improvement after cardiac resynchronization therapy. Circulation. 2006;113:969–76.PubMedCrossRef
25.
Zurück zum Zitat Ypenburg C, van Bommel RJ, Delgado V, et al. Optimal left ventricular lead position predicts reverse remodeling and survival after cardiac resynchronization therapy. J Am Coll Cardiol. 2008;52:1402–9.PubMedCrossRef Ypenburg C, van Bommel RJ, Delgado V, et al. Optimal left ventricular lead position predicts reverse remodeling and survival after cardiac resynchronization therapy. J Am Coll Cardiol. 2008;52:1402–9.PubMedCrossRef
26.
Zurück zum Zitat Murphy RT, Sigurdsson G, Mulamalla S, et al. Tissue synchronization imaging and optimal left ventricular pacing site in cardiac resynchronization therapy. Am J Cardiol. 2006;97:1615–21.PubMedCrossRef Murphy RT, Sigurdsson G, Mulamalla S, et al. Tissue synchronization imaging and optimal left ventricular pacing site in cardiac resynchronization therapy. Am J Cardiol. 2006;97:1615–21.PubMedCrossRef
27.
Zurück zum Zitat Khan FZ, Virdee MS, Palmer CR, et al. Targeted left ventricular lead placement to guide cardiac resynchronization therapy: the TARGET study: a randomized, controlled trial. J Am Coll Cardiol. 2012;59:1509–18.PubMedCrossRef Khan FZ, Virdee MS, Palmer CR, et al. Targeted left ventricular lead placement to guide cardiac resynchronization therapy: the TARGET study: a randomized, controlled trial. J Am Coll Cardiol. 2012;59:1509–18.PubMedCrossRef
28.
Zurück zum Zitat Saba S, Marek J, Schwartzman D, et al. Echocardiography-guided left ventricular lead placement for cardiac resynchronization therapy: results of the Speckle Tracking Assisted Resynchronization Therapy for Electrode Region trial. Circ Heart Fail. 2013;6:427–34.PubMedCrossRef Saba S, Marek J, Schwartzman D, et al. Echocardiography-guided left ventricular lead placement for cardiac resynchronization therapy: results of the Speckle Tracking Assisted Resynchronization Therapy for Electrode Region trial. Circ Heart Fail. 2013;6:427–34.PubMedCrossRef
29.
Zurück zum Zitat Singh JP, Klein HU, Huang DT, et al. Left ventricular lead position and clinical outcome in the multicenter automatic defibrillator implantation trial—cardiac resynchronization therapy (MADIT-CRT) trial. Circulation. 2011;123:1159–66.PubMedCrossRef Singh JP, Klein HU, Huang DT, et al. Left ventricular lead position and clinical outcome in the multicenter automatic defibrillator implantation trial—cardiac resynchronization therapy (MADIT-CRT) trial. Circulation. 2011;123:1159–66.PubMedCrossRef
30.
Zurück zum Zitat Gorcsan III J, Marek JJ, Onishi T. The contemporary role of echocardiography in improving patient response to cardiac resynchronization therapy. Curr Cardiovasc Imaging Rep. 2012;5(6):462–72.PubMedPubMedCentralCrossRef Gorcsan III J, Marek JJ, Onishi T. The contemporary role of echocardiography in improving patient response to cardiac resynchronization therapy. Curr Cardiovasc Imaging Rep. 2012;5(6):462–72.PubMedPubMedCentralCrossRef
31.•
Zurück zum Zitat Boogers MJ, Chen J, van Bommel RJ, et al. Optimal left ventricular lead position assessed with phase analysis on gated myocardial perfusion SPECT. Eur J Nucl Med Mol Imaging. 2011;38:230–8. Article concludes that patients with LV lead position placed concordant to image-guidance showed significant improvement in LV volumes and LV systolic function, whereas patients with a discordant LV lead position showed no significant improvements.PubMedPubMedCentralCrossRef Boogers MJ, Chen J, van Bommel RJ, et al. Optimal left ventricular lead position assessed with phase analysis on gated myocardial perfusion SPECT. Eur J Nucl Med Mol Imaging. 2011;38:230–8. Article concludes that patients with LV lead position placed concordant to image-guidance showed significant improvement in LV volumes and LV systolic function, whereas patients with a discordant LV lead position showed no significant improvements.PubMedPubMedCentralCrossRef
32.
Zurück zum Zitat Khan FZ, Virdee MS, Fynn SP, Dutka DP. Left ventricular lead placement in cardiac resynchronization therapy: where and how? Europace. 2009;11(5):554–61.PubMedCrossRef Khan FZ, Virdee MS, Fynn SP, Dutka DP. Left ventricular lead placement in cardiac resynchronization therapy: where and how? Europace. 2009;11(5):554–61.PubMedCrossRef
33.
Zurück zum Zitat Becker M, Hoffmann R, Schmitz F. Relation of optimal lead positioning as defined by three-dimensional echocardiography to long-term benefit of cardiac resynchronization. Am J Cardiol. 2007;100(11):1671–6.PubMedCrossRef Becker M, Hoffmann R, Schmitz F. Relation of optimal lead positioning as defined by three-dimensional echocardiography to long-term benefit of cardiac resynchronization. Am J Cardiol. 2007;100(11):1671–6.PubMedCrossRef
34.
Zurück zum Zitat Kronborg MB, Kim WY, Mortensen PT, Niesen JC. Non-contrast magnetic resonance imaging for guiding left ventricular lead position in cardiac resynchronization therapy. J Interv Card Electrophysiol. 2012;33(1):27–35.PubMedCrossRef Kronborg MB, Kim WY, Mortensen PT, Niesen JC. Non-contrast magnetic resonance imaging for guiding left ventricular lead position in cardiac resynchronization therapy. J Interv Card Electrophysiol. 2012;33(1):27–35.PubMedCrossRef
35.
Zurück zum Zitat Uebleis C, Ulbrich M, Tegtmeyer R, et al. Electrocardiogram-gated 18F-FDG PET/CT hybrid imaging in patients with unsatisfactory response to cardiac resynchronization therapy: initial clinical results. J Nucl Med. 2011;52:67–71.PubMedCrossRef Uebleis C, Ulbrich M, Tegtmeyer R, et al. Electrocardiogram-gated 18F-FDG PET/CT hybrid imaging in patients with unsatisfactory response to cardiac resynchronization therapy: initial clinical results. J Nucl Med. 2011;52:67–71.PubMedCrossRef
36.
Zurück zum Zitat Lehner S, Uebleis C, Schubler F, et al. The amount of viable and dyssynchronous myocardium is associated with response to cardiac resynchronization therapy: initial clinical results using multiparametric ECG-gated [18F] FDG PET. Eur J Nucl Med Mol Imaging. 2013;40:1876–83.PubMedCrossRef Lehner S, Uebleis C, Schubler F, et al. The amount of viable and dyssynchronous myocardium is associated with response to cardiac resynchronization therapy: initial clinical results using multiparametric ECG-gated [18F] FDG PET. Eur J Nucl Med Mol Imaging. 2013;40:1876–83.PubMedCrossRef
37.
Zurück zum Zitat Friehling M, Chen J, Saba S, et al. A prospective pilot study to evaluate the relationship between acute change in left ventricular synchrony after cardiac resynchronization therapy and patient outcome using a single-injection gated SPECT protocol. Circ Cardiovasc Imaging. 2011;4:532–9.PubMedPubMedCentralCrossRef Friehling M, Chen J, Saba S, et al. A prospective pilot study to evaluate the relationship between acute change in left ventricular synchrony after cardiac resynchronization therapy and patient outcome using a single-injection gated SPECT protocol. Circ Cardiovasc Imaging. 2011;4:532–9.PubMedPubMedCentralCrossRef
38.
Zurück zum Zitat Gorcsan 3rd J, Abraham T, Agler DA. Echocardiography for cardiac resynchronization therapy: recommendations for performance and reporting—a report from the American Society of Echocardiography Dyssynchrony Writing Group endorsed by the Heart Rhythm Society. J Am Soc Echocardiogr. 2008;21:191–213.PubMedCrossRef Gorcsan 3rd J, Abraham T, Agler DA. Echocardiography for cardiac resynchronization therapy: recommendations for performance and reporting—a report from the American Society of Echocardiography Dyssynchrony Writing Group endorsed by the Heart Rhythm Society. J Am Soc Echocardiogr. 2008;21:191–213.PubMedCrossRef
39.
Zurück zum Zitat Chen J, Boogers MM, Bax JJ, Soman P, Garcia EV. The use of nuclear imaging for cardiac resynchronization therapy. Curr Cardiol Rep. 2010;12:185–91.PubMedPubMedCentralCrossRef Chen J, Boogers MM, Bax JJ, Soman P, Garcia EV. The use of nuclear imaging for cardiac resynchronization therapy. Curr Cardiol Rep. 2010;12:185–91.PubMedPubMedCentralCrossRef
40.
Zurück zum Zitat AlJaroudi W, Chen J, Jaber WA, Lloyd SG, Cerqueira MD, Markwick T. Non-echocardiographic imaging in evaluation for cardiac resynchronization therapy. Circ Cardiovasc Imaging. 2011;4:334–43.PubMedPubMedCentralCrossRef AlJaroudi W, Chen J, Jaber WA, Lloyd SG, Cerqueira MD, Markwick T. Non-echocardiographic imaging in evaluation for cardiac resynchronization therapy. Circ Cardiovasc Imaging. 2011;4:334–43.PubMedPubMedCentralCrossRef
41.
Zurück zum Zitat Bax JJ, Delgado V. Myocardial viability as integral part of the diagnostic and therapeutic approach to ischemic heart failure. J Nucl Cardiol. 2015;22(2):229–45.PubMedPubMedCentralCrossRef Bax JJ, Delgado V. Myocardial viability as integral part of the diagnostic and therapeutic approach to ischemic heart failure. J Nucl Cardiol. 2015;22(2):229–45.PubMedPubMedCentralCrossRef
42.
Zurück zum Zitat Bleeker GB, Mollema SA, Holman ER, et al. Left ventricular resynchronization is mandatory for response to cardiac resynchronization therapy: analysis in patients with echocardiographic evidence of left ventricular dyssynchrony at baseline. Circulation. 2007;116:1440–8.PubMedCrossRef Bleeker GB, Mollema SA, Holman ER, et al. Left ventricular resynchronization is mandatory for response to cardiac resynchronization therapy: analysis in patients with echocardiographic evidence of left ventricular dyssynchrony at baseline. Circulation. 2007;116:1440–8.PubMedCrossRef
43.
Zurück zum Zitat Chung ES, Leon AR, Tavazzi L, et al. Results of the Predictors of Response to CRT (PROSPECT) trial. Circulation. 2008;117:2608–16.PubMedCrossRef Chung ES, Leon AR, Tavazzi L, et al. Results of the Predictors of Response to CRT (PROSPECT) trial. Circulation. 2008;117:2608–16.PubMedCrossRef
44.
Zurück zum Zitat Jongbloed MR, Lamb HJ, Bax JJ, et al. Noninvasive visualization of the cardiac venous system using multislice computed tomography. J Am Coll Cardiol. 2005;45:749–53.PubMedCrossRef Jongbloed MR, Lamb HJ, Bax JJ, et al. Noninvasive visualization of the cardiac venous system using multislice computed tomography. J Am Coll Cardiol. 2005;45:749–53.PubMedCrossRef
45.
Zurück zum Zitat Van de Veire NR, Schuijf JD, De Sutter J, et al. Noninvasive visualization of the cardiac venous system in coronary artery disease patients using 64-slice computed tomography. J Am Coll Cardiol. 2006;48:1832–8.PubMedCrossRef Van de Veire NR, Schuijf JD, De Sutter J, et al. Noninvasive visualization of the cardiac venous system in coronary artery disease patients using 64-slice computed tomography. J Am Coll Cardiol. 2006;48:1832–8.PubMedCrossRef
46.
Zurück zum Zitat Nieman K, Shapiro MD, Ferencik M, et al. Reperfused myocardial infarction: contrast-enhanced 64-section CT in comparison to MR imaging. Radiology. 2008;247:49–56.PubMedCrossRef Nieman K, Shapiro MD, Ferencik M, et al. Reperfused myocardial infarction: contrast-enhanced 64-section CT in comparison to MR imaging. Radiology. 2008;247:49–56.PubMedCrossRef
47.
Zurück zum Zitat Truong QA, Singh JP, Cannon CP, et al. Quantitative analysis of intraventricular dyssynchrony using wall thickness by multidetector computed tomography. JACC Cardiovasc Imaging. 2008;1:772–81.PubMedPubMedCentralCrossRef Truong QA, Singh JP, Cannon CP, et al. Quantitative analysis of intraventricular dyssynchrony using wall thickness by multidetector computed tomography. JACC Cardiovasc Imaging. 2008;1:772–81.PubMedPubMedCentralCrossRef
49.
Zurück zum Zitat Chen J, Bax JJ, Henneman MM, Boogers MJ, Garcia EV. Is nuclear imaging a viable alternative technique to assess dyssynchrony? Europace. 2008;10 Suppl 3:iii101–5.PubMed Chen J, Bax JJ, Henneman MM, Boogers MJ, Garcia EV. Is nuclear imaging a viable alternative technique to assess dyssynchrony? Europace. 2008;10 Suppl 3:iii101–5.PubMed
50.
Zurück zum Zitat Boogers MM, Chen J, Bax JJ. Myocardial perfusion single photon emission computed tomography for the assessment of mechanical dyssynchrony. Curr Opin Cardiol. 2008;23:431–9.PubMedCrossRef Boogers MM, Chen J, Bax JJ. Myocardial perfusion single photon emission computed tomography for the assessment of mechanical dyssynchrony. Curr Opin Cardiol. 2008;23:431–9.PubMedCrossRef
51.
Zurück zum Zitat Boogers MM, Chen J, Bax JJ. Role of nuclear imaging in cardiac resynchronization therapy. Expert Rev Cardiovasc Ther. 2009;7:65–72.PubMedCrossRef Boogers MM, Chen J, Bax JJ. Role of nuclear imaging in cardiac resynchronization therapy. Expert Rev Cardiovasc Ther. 2009;7:65–72.PubMedCrossRef
52.
Zurück zum Zitat Schwartzman D, Chang I, Michele JJ, Mirotznik MS, Foster KR. Electrical impedance properties of normal and chronically infarcted ventricular myocardium. J Interv Card Electrophysiol. 1999;3:213–24.PubMedCrossRef Schwartzman D, Chang I, Michele JJ, Mirotznik MS, Foster KR. Electrical impedance properties of normal and chronically infarcted ventricular myocardium. J Interv Card Electrophysiol. 1999;3:213–24.PubMedCrossRef
53.
Zurück zum Zitat Reddy VY, Wrobleski D, Houghtaling C, Josephson ME, Ruskin JN. Combined epicardial and endocardial electroanatomic mapping in a porcine model of healed myocardial infarction. Circulation. 2003;107:3236–42.PubMedCrossRef Reddy VY, Wrobleski D, Houghtaling C, Josephson ME, Ruskin JN. Combined epicardial and endocardial electroanatomic mapping in a porcine model of healed myocardial infarction. Circulation. 2003;107:3236–42.PubMedCrossRef
54.
Zurück zum Zitat Tedrow U, Maisel WH, Epstein LM, Soejima K, Stevenson WG. Feasibility of adjusting paced left ventricular activation by manipulating stimulus strength. J Am Coll Cardiol. 2004;44:2249–52.PubMedCrossRef Tedrow U, Maisel WH, Epstein LM, Soejima K, Stevenson WG. Feasibility of adjusting paced left ventricular activation by manipulating stimulus strength. J Am Coll Cardiol. 2004;44:2249–52.PubMedCrossRef
55.
Zurück zum Zitat Breithardt OA, Stellbrink C, Kramer AP, et al. Echocardiographic quantification of left ventricular asynchrony predicts an acute hemodynamic benefit of cardiac resynchronization therapy. J Am Coll Cardiol. 2002;40:536–45.PubMedCrossRef Breithardt OA, Stellbrink C, Kramer AP, et al. Echocardiographic quantification of left ventricular asynchrony predicts an acute hemodynamic benefit of cardiac resynchronization therapy. J Am Coll Cardiol. 2002;40:536–45.PubMedCrossRef
56.
Zurück zum Zitat Gibbons RJ, Verani MS, Behrenbeck T, et al. Feasibility of tomographic technetium-99m-hexakis-2- methylpropyl-isonitrile imaging for the assessment of myocardial area at risk and the effect of acute treatment in myocardial infarction. Circulation. 1989;80:1277–86.PubMedCrossRef Gibbons RJ, Verani MS, Behrenbeck T, et al. Feasibility of tomographic technetium-99m-hexakis-2- methylpropyl-isonitrile imaging for the assessment of myocardial area at risk and the effect of acute treatment in myocardial infarction. Circulation. 1989;80:1277–86.PubMedCrossRef
57.
Zurück zum Zitat O’Connor MD, Gibbons RJ, Juny JE, O’Keefe JH, Ali A. Quantitative myocardial SPECT for infarct sizing: feasibility of a multicenter trial evaluated using a cardiac phantom. J Nucl Med. 1995;36:1130–6.PubMed O’Connor MD, Gibbons RJ, Juny JE, O’Keefe JH, Ali A. Quantitative myocardial SPECT for infarct sizing: feasibility of a multicenter trial evaluated using a cardiac phantom. J Nucl Med. 1995;36:1130–6.PubMed
58.
Zurück zum Zitat O’Connor MK, Hammell T, Gibbons RJ. In vitro validation of a simple tomographic technique for estimation of percentage myocardium at risk using methoxyisobutyl isonitrile technetium 99m (sestamibi). Eur J Nucl Med. 1990;17:69–76.PubMedCrossRef O’Connor MK, Hammell T, Gibbons RJ. In vitro validation of a simple tomographic technique for estimation of percentage myocardium at risk using methoxyisobutyl isonitrile technetium 99m (sestamibi). Eur J Nucl Med. 1990;17:69–76.PubMedCrossRef
59.
Zurück zum Zitat Medrano R, Lowry RW, Young JB, et al. Assessment of myocardial viability with Tc-99m sestamibi in patients undergoing cardiac transplantation. Circulation. 1996;94:1010–7.PubMedCrossRef Medrano R, Lowry RW, Young JB, et al. Assessment of myocardial viability with Tc-99m sestamibi in patients undergoing cardiac transplantation. Circulation. 1996;94:1010–7.PubMedCrossRef
60.
Zurück zum Zitat Maes AF, Borgers M, Flameng W, et al. Assessment of myocardial viability in chronic coronary artery disease using technetioum-99m sestamibi SPECT. J Am Coll Cardiol. 1997;29:62–8.PubMedCrossRef Maes AF, Borgers M, Flameng W, et al. Assessment of myocardial viability in chronic coronary artery disease using technetioum-99m sestamibi SPECT. J Am Coll Cardiol. 1997;29:62–8.PubMedCrossRef
61.
Zurück zum Zitat Dakik HA, Howell JF, Lawrie GM, Espada R, Weibaecher DG. Assessment of myocardial viability with 99m Tc-sestamibi tomography before coronary bypass graft surgery: correlation with histopathology and postoperative improvement in cardiac function. Circulation. 1997;96:2892–8.PubMedCrossRef Dakik HA, Howell JF, Lawrie GM, Espada R, Weibaecher DG. Assessment of myocardial viability with 99m Tc-sestamibi tomography before coronary bypass graft surgery: correlation with histopathology and postoperative improvement in cardiac function. Circulation. 1997;96:2892–8.PubMedCrossRef
62.
Zurück zum Zitat Riedlbauchova L, Brunken R, Jaber WA, et al. The impact of myocardial viability on the clinical outcome of cardiac resynchronization therapy. J Cardiovasc Electrophysiol. 2009;20:50–7.PubMedCrossRef Riedlbauchova L, Brunken R, Jaber WA, et al. The impact of myocardial viability on the clinical outcome of cardiac resynchronization therapy. J Cardiovasc Electrophysiol. 2009;20:50–7.PubMedCrossRef
63.
Zurück zum Zitat Bose A, Kandala J, Upadhyay GA, et al. Impact of myocardial viability and left ventricular lead location on clinical outcome in cardiac resynchronization therapy recipients with ischemic cardiomyopathy. J Cardiovasc Electrophysiol. 2014;25:507–13.PubMedCrossRef Bose A, Kandala J, Upadhyay GA, et al. Impact of myocardial viability and left ventricular lead location on clinical outcome in cardiac resynchronization therapy recipients with ischemic cardiomyopathy. J Cardiovasc Electrophysiol. 2014;25:507–13.PubMedCrossRef
64.
Zurück zum Zitat Ypenburg C, Schalij MJ, Bleeker GB, et al. Impact of viability and scar tissue on response to cardiac resynchronization therapy in ischaemic heart failure patients. Eur Heart J. 2007;28:33–41.PubMedCrossRef Ypenburg C, Schalij MJ, Bleeker GB, et al. Impact of viability and scar tissue on response to cardiac resynchronization therapy in ischaemic heart failure patients. Eur Heart J. 2007;28:33–41.PubMedCrossRef
65.
Zurück zum Zitat Ficaro EP, Lee BC, Kritzman JN, Corbett JR. Corridor4DM: the Michigan method for quantitative nuclear cardiology. J Nucl Cardiol. 2007;14:455–65.PubMedCrossRef Ficaro EP, Lee BC, Kritzman JN, Corbett JR. Corridor4DM: the Michigan method for quantitative nuclear cardiology. J Nucl Cardiol. 2007;14:455–65.PubMedCrossRef
66.
Zurück zum Zitat Berman DS, Kang X, Gransar H. Quantitative assessment of myocardial perfusion abnormality on SPECT myocardial perfusion imaging is more reproducible than expert visual analysis. J Nucl Cardiol. 2009;16:45–53.PubMedPubMedCentralCrossRef Berman DS, Kang X, Gransar H. Quantitative assessment of myocardial perfusion abnormality on SPECT myocardial perfusion imaging is more reproducible than expert visual analysis. J Nucl Cardiol. 2009;16:45–53.PubMedPubMedCentralCrossRef
67.
Zurück zum Zitat Bleeker GB, Mollema SA, Holman ER, et al. Left ventricular resynchronization is mandatory for response to cardiac resynchronization therapy: analysis in patients with echocardiographic evidence of left ventricular dyssynchrony at baseline. Circulation. 2007;116:1440–8.PubMedCrossRef Bleeker GB, Mollema SA, Holman ER, et al. Left ventricular resynchronization is mandatory for response to cardiac resynchronization therapy: analysis in patients with echocardiographic evidence of left ventricular dyssynchrony at baseline. Circulation. 2007;116:1440–8.PubMedCrossRef
68.
Zurück zum Zitat Chen J, Garcia EV, Folks RD, et al. Onset of left ventricular mechanical contraction as determined by phase analysis of ECG-gated myocardial perfusion SPECT imaging: development of a diagnostic tool for assessment of cardiac mechanical dyssynchrony. J Nucl Cardiol. 2005;12:687–95.PubMedCrossRef Chen J, Garcia EV, Folks RD, et al. Onset of left ventricular mechanical contraction as determined by phase analysis of ECG-gated myocardial perfusion SPECT imaging: development of a diagnostic tool for assessment of cardiac mechanical dyssynchrony. J Nucl Cardiol. 2005;12:687–95.PubMedCrossRef
69.
Zurück zum Zitat Trimble MA, Borges-Neto S, Smallheiser S, et al. Evaluation of left ventricular mechanical dyssynchrony as determined by phase analysis of ECG-gated SPECT myocardial perfusion imaging in patients with left ventricular dysfunction and conduction disturbances. J Nucl Cardiol. 2007;14:298–307.PubMedCrossRef Trimble MA, Borges-Neto S, Smallheiser S, et al. Evaluation of left ventricular mechanical dyssynchrony as determined by phase analysis of ECG-gated SPECT myocardial perfusion imaging in patients with left ventricular dysfunction and conduction disturbances. J Nucl Cardiol. 2007;14:298–307.PubMedCrossRef
70.
Zurück zum Zitat Trimble MA, Borges-Neto S, Honeycutt EF, et al. Evaluation of mechanical dyssynchrony and myocardial perfusion using phase analysis of gated SPECT imaging in patients with left ventricular dysfunction. J Nucl Cardiol. 2008;15:663–70.PubMedPubMedCentralCrossRef Trimble MA, Borges-Neto S, Honeycutt EF, et al. Evaluation of mechanical dyssynchrony and myocardial perfusion using phase analysis of gated SPECT imaging in patients with left ventricular dysfunction. J Nucl Cardiol. 2008;15:663–70.PubMedPubMedCentralCrossRef
71.
Zurück zum Zitat Chen J, Faber TL, Cooke CD, Garcia EV. Temporal resolution of multiharmonic phase analysis of ECG-gated myocardial perfusion SPECT studies. J Nucl Cardiol. 2008;15:383–91.PubMedPubMedCentralCrossRef Chen J, Faber TL, Cooke CD, Garcia EV. Temporal resolution of multiharmonic phase analysis of ECG-gated myocardial perfusion SPECT studies. J Nucl Cardiol. 2008;15:383–91.PubMedPubMedCentralCrossRef
72.
Zurück zum Zitat Trimble MA, Velazquez EJ, Adams GL, et al. Repeatability and reproducibility of phase analysis of gated single-photon emission computed tomography myocardial perfusion imaging used to quantify cardiac dyssynchrony. Nucl Med Commun. 2008;29:374–81.PubMedPubMedCentralCrossRef Trimble MA, Velazquez EJ, Adams GL, et al. Repeatability and reproducibility of phase analysis of gated single-photon emission computed tomography myocardial perfusion imaging used to quantify cardiac dyssynchrony. Nucl Med Commun. 2008;29:374–81.PubMedPubMedCentralCrossRef
73.
Zurück zum Zitat Lin X, Xu H, Zhao X, et al. Repeatability of left ventricular dyssynchrony and function parameters in serial gated myocardial perfusion SPECT studies. J Nucl Cardiol. 2010;17:811–6.PubMedPubMedCentralCrossRef Lin X, Xu H, Zhao X, et al. Repeatability of left ventricular dyssynchrony and function parameters in serial gated myocardial perfusion SPECT studies. J Nucl Cardiol. 2010;17:811–6.PubMedPubMedCentralCrossRef
74.
Zurück zum Zitat Pazhenkottil AP, Buechel RR, Herzog BA, et al. Ultrafast assessment of left ventricular dyssynchrony from nuclear myocardial perfusion imaging on a new high-speed gamma camera. Eur J Nucl Med Mol Imaging. 2010;37:2086–92.PubMedCrossRef Pazhenkottil AP, Buechel RR, Herzog BA, et al. Ultrafast assessment of left ventricular dyssynchrony from nuclear myocardial perfusion imaging on a new high-speed gamma camera. Eur J Nucl Med Mol Imaging. 2010;37:2086–92.PubMedCrossRef
75.
Zurück zum Zitat Aljaroudi W, Koneru J, Heo J, Iskandrian AE. Impact of ischemia on left ventricular dyssynchrony by phase analysis of gated single photon emission computed tomography myocardial perfusion imaging. J Nucl Cardiol. 2011;18:36–42.PubMedCrossRef Aljaroudi W, Koneru J, Heo J, Iskandrian AE. Impact of ischemia on left ventricular dyssynchrony by phase analysis of gated single photon emission computed tomography myocardial perfusion imaging. J Nucl Cardiol. 2011;18:36–42.PubMedCrossRef
76.
Zurück zum Zitat AlJaroudi W, Iqbal F, Heo J, Iskandrian AE. Relation between heart rate and left ventricular mechanical dyssynchrony in patients with end-stage renal disease. Am J Cardiol. 2011;107:1235–40.CrossRef AlJaroudi W, Iqbal F, Heo J, Iskandrian AE. Relation between heart rate and left ventricular mechanical dyssynchrony in patients with end-stage renal disease. Am J Cardiol. 2011;107:1235–40.CrossRef
77.
Zurück zum Zitat Cheung A, Zhou Y, Faber TL, Garcia EV, Zhu L, Chen J. The performance of phase analysis of gated SPECT myocardial perfusion imaging in the presence of perfusion defects: a simulation study. J Nucl Cardiol. 2012;19:500–6.PubMedPubMedCentralCrossRef Cheung A, Zhou Y, Faber TL, Garcia EV, Zhu L, Chen J. The performance of phase analysis of gated SPECT myocardial perfusion imaging in the presence of perfusion defects: a simulation study. J Nucl Cardiol. 2012;19:500–6.PubMedPubMedCentralCrossRef
78.
Zurück zum Zitat Henneman MM, Chen J, Ypenburg C, et al. Phase analysis of gated myocardial perfusion SPECT compared to tissue Doppler imaging for the assessment of left ventricular dyssynchrony. J Am Coll Cardiol. 2007;49:1708–14.PubMedCrossRef Henneman MM, Chen J, Ypenburg C, et al. Phase analysis of gated myocardial perfusion SPECT compared to tissue Doppler imaging for the assessment of left ventricular dyssynchrony. J Am Coll Cardiol. 2007;49:1708–14.PubMedCrossRef
79.
Zurück zum Zitat Marsan NA, Henneman MM, Chen J, et al. Left ventricular dyssynchrony assessed by two 3-dimensional imaging modalities: phase analysis of gated myocardial perfusion SPECT and tri-plane tissue Doppler imaging. Eur J Nucl Med Mol Imaging. 2008;35:166–73.PubMedCrossRef Marsan NA, Henneman MM, Chen J, et al. Left ventricular dyssynchrony assessed by two 3-dimensional imaging modalities: phase analysis of gated myocardial perfusion SPECT and tri-plane tissue Doppler imaging. Eur J Nucl Med Mol Imaging. 2008;35:166–73.PubMedCrossRef
80.
Zurück zum Zitat Samad Z, Atchley AE, Trimble MA, et al. Prevalence and predictors of mechanical dyssynchrony as defined by phase analysis in patients with left ventricular dysfunction undergoing gated SPECT myocardial perfusion imaging. J Nucl Cardiol. 2011;18:24–30.PubMedPubMedCentralCrossRef Samad Z, Atchley AE, Trimble MA, et al. Prevalence and predictors of mechanical dyssynchrony as defined by phase analysis in patients with left ventricular dysfunction undergoing gated SPECT myocardial perfusion imaging. J Nucl Cardiol. 2011;18:24–30.PubMedPubMedCentralCrossRef
81.
Zurück zum Zitat Henneman MM, Chen J, Dibbets-Schneider P, et al. Can LV dyssynchrony as assessed with phase analysis on gated myocardial perfusion SPECT predict response to CRT? J Nucl Med. 2007;48:1104–11.PubMedCrossRef Henneman MM, Chen J, Dibbets-Schneider P, et al. Can LV dyssynchrony as assessed with phase analysis on gated myocardial perfusion SPECT predict response to CRT? J Nucl Med. 2007;48:1104–11.PubMedCrossRef
82.
Zurück zum Zitat IAEA-VISION CRT. Nuclear Cardiology in Congestive Heart Failure Value of Intraventricular Synchronism Assessment by Gated-SPECT Myocardial Perfusion Imaging in the Management of Heart Failure Patients Submitted to Cardiac Resynchronization Therapy. IAEA annual report 2013, additional annex information. IAEA-VISION CRT. Nuclear Cardiology in Congestive Heart Failure Value of Intraventricular Synchronism Assessment by Gated-SPECT Myocardial Perfusion Imaging in the Management of Heart Failure Patients Submitted to Cardiac Resynchronization Therapy. IAEA annual report 2013, additional annex information.
83.
Zurück zum Zitat Dekker AL, Phelps B, Dijkman B. Epicardial left ventricular lead placement for cardiac resynchronization therapy: optimal pace site selection with pressure-volume loops. J Thorac Cardiovasc Surg. 2004;127:1641–7.PubMedCrossRef Dekker AL, Phelps B, Dijkman B. Epicardial left ventricular lead placement for cardiac resynchronization therapy: optimal pace site selection with pressure-volume loops. J Thorac Cardiovasc Surg. 2004;127:1641–7.PubMedCrossRef
85.•
Zurück zum Zitat Zhou W, Hou X, Piccinelli M, et al. 3D fusion of LV venous anatomy on fluoroscopy venograms with epicardial surface on SPECT myocardial perfusion images for guiding CRT LV lead placement. JACC Cardiovasc Imaging. 2014;7:1239–48. Article describes image guided method for accurate CRT LV lead placement. Zhou W, Hou X, Piccinelli M, et al. 3D fusion of LV venous anatomy on fluoroscopy venograms with epicardial surface on SPECT myocardial perfusion images for guiding CRT LV lead placement. JACC Cardiovasc Imaging. 2014;7:1239–48. Article describes image guided method for accurate CRT LV lead placement.
Metadaten
Titel
Nuclear Image-Guided Approaches for Cardiac Resynchronization Therapy (CRT)
verfasst von
Weihua Zhou
Ernest V. Garcia
Publikationsdatum
01.01.2016
Verlag
Springer US
Erschienen in
Current Cardiology Reports / Ausgabe 1/2016
Print ISSN: 1523-3782
Elektronische ISSN: 1534-3170
DOI
https://doi.org/10.1007/s11886-015-0687-4

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