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Current Cardiology Reports
Erschienen in: Current Cardiology Reports 11/2017

01.11.2017 | Psychological Aspects of Cardiovascular Diseases (A Steptoe, Section Editor)

Psychological Stress, Inflammation, and Coronary Heart Disease

verfasst von: Petra H. Wirtz, Roland von Känel

Erschienen in: Current Cardiology Reports | Ausgabe 11/2017

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Abstract

Purpose of Review

In this review, we summarize evidence on the risk factor psychological stress in the context of coronary heart disease (CHD) in humans and explore the role of inflammation as a potential underlying mechanism.

Recent Findings

While chronic stress increases the risk of incident CHD and poor cardiovascular prognosis, acute emotional stress can trigger acute CHD events in vulnerable patients. Evidence supporting a potential role for inflammation as a promising biological mechanism comes from population-based studies showing associations between chronic stress and increased inflammation. Similarly, experimental studies demonstrate acute stress-induced increases in inflammatory markers and suggest modulatory potential for pharmacological and biobehavioral interventions. So far, studies investigating patients with cardiovascular disease are few and the full sequence of events from stress to inflammation to CHD remains to be established.

Summary

Psychological stress is an independent CHD risk factor associated with increased inflammation. Although promising, causality needs to be further explored.
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Metadaten
Titel
Psychological Stress, Inflammation, and Coronary Heart Disease
verfasst von
Petra H. Wirtz
Roland von Känel
Publikationsdatum
01.11.2017
Verlag
Springer US
Erschienen in
Current Cardiology Reports / Ausgabe 11/2017
Print ISSN: 1523-3782
Elektronische ISSN: 1534-3170
DOI
https://doi.org/10.1007/s11886-017-0919-x

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