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Erschienen in:

01.08.2013 | Microvascular Complications-Neuropathy (D Ziegler, Section Editor)

Magnetic Resonance Imaging of the Central Nervous System in Diabetic Neuropathy

verfasst von: Iain D. Wilkinson, Dinesh Selvarajah, Marni Greig, Pallai Shillo, Elaine Boland, Rajiv Gandhi, Solomon Tesfaye

Erschienen in: Current Diabetes Reports | Ausgabe 4/2013

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Abstract

Diabetic ‘peripheral’ neuropathy (DPN) is one of the common sequelae to the development of both type-1 and type-2 diabetes mellitus. Neuropathy has a major negative impact on quality of life. Abnormalities in both peripheral vasculature and nerve function are well documented and, in addition, evidence is emerging regarding changes within the central nervous system (CNS) that are concomitant with the presence of DPN. The often-resistant nature of DPN to medical treatment highlights the need to understand the role of the CNS in neuropathic symptomatology and progression, as this may modulate therapeutic approaches. Advanced neuroimaging techniques, especially those that can provide quantitative measures of structure and function, can provide objective markers of CNS status. With that comes great potential for not only furthering our understanding of involvement of the CNS in neuropathic etiology but also most importantly aiding the development of new and more effective, targeted, analgesic interventions.

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Titel: Magnetic Resonance Imaging of the Central Nervous System in Diabetic Neuropathy
verfasst von: Iain D. Wilkinson
Dinesh Selvarajah
Marni Greig
Pallai Shillo
Elaine Boland
Rajiv Gandhi
Solomon Tesfaye
Publikationsdatum: 01.08.2013
Verlag: Springer US
Erschienen in: Current Diabetes Reports / Ausgabe 4/2013
Print ISSN: 1534-4827
Elektronische ISSN: 1539-0829
DOI: https://doi.org/10.1007/s11892-013-0394-8

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