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Current Gastroenterology Reports

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01.06.2014 | Small Intestine (J Sellin, Section Editor)

Tropical Sprue in 2014: the New Face of an Old Disease

verfasst von: Uday C. Ghoshal, Deepakshi Srivastava, Abhai Verma, Ujjala Ghoshal

Erschienen in: Current Gastroenterology Reports | Ausgabe 6/2014

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Abstract

Tropical sprue (TS), once known to be a common cause of malabsorption syndrome (MAS) in India and other tropical countries, is believed to be uncommon currently in spite of contrary evidence. Several recent studies from India showed TS to be the commonest cause of sporadic MAS in Indian adults. TS is diagnosed in patients presenting with suggestive clinical presentation, which cannot be explained by another cause of MAS and investigations revealing malabsorption of two unrelated substances, abnormal small-intestinal mucosal histology, which responds to treatment with antibiotics such as tetracycline and folic acid. There is substantial overlap between TS and postinfectious irritable bowel syndrome. There have been several advances in epidemiology, pathogenesis, and diagnosis of TS, hitherto an enigmatic condition.

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Titel: Tropical Sprue in 2014: the New Face of an Old Disease
verfasst von: Uday C. Ghoshal
Deepakshi Srivastava
Abhai Verma
Ujjala Ghoshal
Publikationsdatum: 01.06.2014
Verlag: Springer US
Erschienen in: Current Gastroenterology Reports / Ausgabe 6/2014
Print ISSN: 1522-8037
Elektronische ISSN: 1534-312X
DOI: https://doi.org/10.1007/s11894-014-0391-3

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