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Erschienen in: Current HIV/AIDS Reports 4/2014

01.12.2014 | Behavioral-Bio-Medical Interface (JL Brown and RJ DiClemente, Section Editors)

Optimizing ART Adherence: Update for HIV Treatment and Prevention

verfasst von: Reuben N. Robbins, Anya Y. Spector, Claude A. Mellins, Robert H. Remien

Erschienen in: Current HIV/AIDS Reports | Ausgabe 4/2014

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Abstract

Optimal adherence to antiretroviral therapy (ART) is central to achieving viral suppression and positive health outcomes in HIV-infected individuals. Virally suppressed individuals can also reduce the risk of HIV transmission to uninfected partners. Hence, adherence to ART has become both an HIV treatment and an HIV prevention strategy. However, achieving optimal ART adherence can be challenging, especially over the long term. It is increasingly important for clinicians and researchers to be abreast of the most recent developments in the field as new biomedical approaches to treatment emerge and as guidelines for the use of pre-exposure prophylaxis (PrEP) are disseminated to providers serving HIV affected populations. Several reviews have described numerous ART adherence interventions that have been developed and/or tested with the most recent review including literature up to 2012. To augment the literature, we present a review of ART adherence interventions from 2013 to the present. We included peer-reviewed journals as well as abstracts from two key conferences.
Literatur
1.
Zurück zum Zitat Meichenbaum D, Turk DC. Facilitating treatment adherence: a practitioner’s guidebook. The University of Michigan: Plenum Press; 1987. 310 p.CrossRef Meichenbaum D, Turk DC. Facilitating treatment adherence: a practitioner’s guidebook. The University of Michigan: Plenum Press; 1987. 310 p.CrossRef
2.
Zurück zum Zitat Hertogs K, Bloor S, Vroey VD, Eynde CD, Dehertogh P, Cauwenberge A, et al. A novel human immunodeficiency virus type 1 reverse transcriptase mutational pattern confers phenotypic lamivudine resistance in the absence of mutation 184V. Antimicrobial Agents Chemotherapy. 2000;44(3):568–73.PubMedCentralPubMedCrossRef Hertogs K, Bloor S, Vroey VD, Eynde CD, Dehertogh P, Cauwenberge A, et al. A novel human immunodeficiency virus type 1 reverse transcriptase mutational pattern confers phenotypic lamivudine resistance in the absence of mutation 184V. Antimicrobial Agents Chemotherapy. 2000;44(3):568–73.PubMedCentralPubMedCrossRef
3.
Zurück zum Zitat Hogg RS, Heath K, Bangsberg D, Yip B, Press N, O’Shaughnessy MV, et al. Intermittent use of triple-combination therapy is predictive of mortality at baseline and after 1 year of follow-up. AIDS. 2002;17(7):1051–8.CrossRef Hogg RS, Heath K, Bangsberg D, Yip B, Press N, O’Shaughnessy MV, et al. Intermittent use of triple-combination therapy is predictive of mortality at baseline and after 1 year of follow-up. AIDS. 2002;17(7):1051–8.CrossRef
4.
Zurück zum Zitat Kozal MJ, Rivet AK, Chiarella J, Schreibman T, Cornman D, Fisher W, et al. Antiretroviral resistance and high-risk transmission behavior among HIV-positive patients in clinical care. AIDS. 2004;18(16):2185–9.PubMedCrossRef Kozal MJ, Rivet AK, Chiarella J, Schreibman T, Cornman D, Fisher W, et al. Antiretroviral resistance and high-risk transmission behavior among HIV-positive patients in clinical care. AIDS. 2004;18(16):2185–9.PubMedCrossRef
5.
Zurück zum Zitat Mannheimer S, Friedland G, Matts J, Child C, Chesney M. The consistency of adherence to antiretroviral therapy predicts biologic outcomes for human immunodeficiency virus-infected persons in clinical trials. Clin Infect Dis. 2002;34(8):1115–21.PubMedCrossRef Mannheimer S, Friedland G, Matts J, Child C, Chesney M. The consistency of adherence to antiretroviral therapy predicts biologic outcomes for human immunodeficiency virus-infected persons in clinical trials. Clin Infect Dis. 2002;34(8):1115–21.PubMedCrossRef
6.
Zurück zum Zitat McNabb J, Ross JW, Abriola K, Turley C, Nightingale CH, Nicolau DP. Adherence to highly active antiretroviral therapy predicts virologic outcome at an inner-city human immunodeficiency virus clinic. Clin Infect Dis. 2001;33(5):700–5.PubMedCrossRef McNabb J, Ross JW, Abriola K, Turley C, Nightingale CH, Nicolau DP. Adherence to highly active antiretroviral therapy predicts virologic outcome at an inner-city human immunodeficiency virus clinic. Clin Infect Dis. 2001;33(5):700–5.PubMedCrossRef
7.
Zurück zum Zitat Wood E, Hogg RS, Yip B, Harrigan PR, O’Shaughnessy MV, Montaner JS. Effect of medication adherence on survival of HIV infected adults who start highly active antiretroviral therapy when the CD4? cell count is 0.200 to 0.350 9 10(9) cells/L. Ann Intern Med. 2003;139:810–6.PubMedCrossRef Wood E, Hogg RS, Yip B, Harrigan PR, O’Shaughnessy MV, Montaner JS. Effect of medication adherence on survival of HIV infected adults who start highly active antiretroviral therapy when the CD4? cell count is 0.200 to 0.350 9 10(9) cells/L. Ann Intern Med. 2003;139:810–6.PubMedCrossRef
8.
Zurück zum Zitat Pasternak AO, de Bruin M, Jurriaans S, Bakker M, Berkhout B, Prins JM, et al. (2012) Modest nonadherence to antiretroviral therapy promotes residual HIV-1 replication in the absence of virological rebound in plasma. J Infect Dis 210(3) Pasternak AO, de Bruin M, Jurriaans S, Bakker M, Berkhout B, Prins JM, et al. (2012) Modest nonadherence to antiretroviral therapy promotes residual HIV-1 replication in the absence of virological rebound in plasma. J Infect Dis 210(3)
10.
Zurück zum Zitat Granich RM, Gilks CF, Dye C, De Cock KM, Williams BG. Universal voluntary HIV testing with immediate antiretroviral therapy as a strategy for elimination of HIV transmission: a mathematical model. Lancet. 2009;373:48–57.PubMedCrossRef Granich RM, Gilks CF, Dye C, De Cock KM, Williams BG. Universal voluntary HIV testing with immediate antiretroviral therapy as a strategy for elimination of HIV transmission: a mathematical model. Lancet. 2009;373:48–57.PubMedCrossRef
11.
Zurück zum Zitat Walensky RP, Paltiel AD, Losina E, Morris BL, Scott CA, Rhode ER, et al. Test and treat DC: forecasting the impact of a comprehensive HIV strategy in Washington DC. Clin Infect Dis. 2010;51(4):392–400.PubMedCentralPubMedCrossRef Walensky RP, Paltiel AD, Losina E, Morris BL, Scott CA, Rhode ER, et al. Test and treat DC: forecasting the impact of a comprehensive HIV strategy in Washington DC. Clin Infect Dis. 2010;51(4):392–400.PubMedCentralPubMedCrossRef
12.
Zurück zum Zitat Centers for Disease Control. Vital signs: HIV prevention through care and treatment. MMWR CDC Surveillance Summary. 2011;60(47):1618–23. Centers for Disease Control. Vital signs: HIV prevention through care and treatment. MMWR CDC Surveillance Summary. 2011;60(47):1618–23.
13.
Zurück zum Zitat Gardner EM, McLees MP, Steiner JF, del Rio C, Burman WJ. The spectrum of engagement in HIV care and its relevance to test-and-treat strategies for prevention of HIV infection. Clin Infect Dis. 2011;52(6):793–800.PubMedCentralPubMedCrossRef Gardner EM, McLees MP, Steiner JF, del Rio C, Burman WJ. The spectrum of engagement in HIV care and its relevance to test-and-treat strategies for prevention of HIV infection. Clin Infect Dis. 2011;52(6):793–800.PubMedCentralPubMedCrossRef
15.
Zurück zum Zitat Kashuba AD, Dyer JR, Kramer LM, Raasch RH, Eron JJ, Cohen MS. Antiretroviral-drug concentrations in semen: implications for sexual transmission of human immunodeficiency virus type 1. Antimicrob Agents Chemother. 1999;43:1817–26.PubMedCentralPubMed Kashuba AD, Dyer JR, Kramer LM, Raasch RH, Eron JJ, Cohen MS. Antiretroviral-drug concentrations in semen: implications for sexual transmission of human immunodeficiency virus type 1. Antimicrob Agents Chemother. 1999;43:1817–26.PubMedCentralPubMed
16.
Zurück zum Zitat Karim QA, Karim SSA, Frohlich JA, Grobler AC, Baxter C, Mansoor LE, et al. Effectiveness and safety of tenofovir gel, an antiretroviral microbicide, for the prevention of HIV infection in women. Science. 2010;329(5996):1168–74.CrossRef Karim QA, Karim SSA, Frohlich JA, Grobler AC, Baxter C, Mansoor LE, et al. Effectiveness and safety of tenofovir gel, an antiretroviral microbicide, for the prevention of HIV infection in women. Science. 2010;329(5996):1168–74.CrossRef
17.
Zurück zum Zitat Grant RM. Antiretroviral agents used by HIV-uninfected persons for prevention: pre- and postexposure prophylaxis. Clin Infect Dis. 2010;50(Supplement 3):S96–S101.PubMedCentralPubMedCrossRef Grant RM. Antiretroviral agents used by HIV-uninfected persons for prevention: pre- and postexposure prophylaxis. Clin Infect Dis. 2010;50(Supplement 3):S96–S101.PubMedCentralPubMedCrossRef
18.
Zurück zum Zitat Baeten JM, Donnell D, Ndase P, Mugo NR, Campbell JD, Wangisi J, et al. Antiretroviral prophylaxis for HIV prevention in heterosexual men and women. N Engl J Med. 2012;367:399–410.PubMedCentralPubMedCrossRef Baeten JM, Donnell D, Ndase P, Mugo NR, Campbell JD, Wangisi J, et al. Antiretroviral prophylaxis for HIV prevention in heterosexual men and women. N Engl J Med. 2012;367:399–410.PubMedCentralPubMedCrossRef
19.
Zurück zum Zitat Nicol MR, Adams JL, Kashuba ADM (2013) HIV PrEP trials: the road to success. Clin Investig 3(3) Nicol MR, Adams JL, Kashuba ADM (2013) HIV PrEP trials: the road to success. Clin Investig 3(3)
20.
Zurück zum Zitat Boffito M, Jackson A, Asboe D. Pharmacology lessons from chemoprophylaxis studies. Clin Infect Dis. 2014;59(supplement 1):S52–S4.PubMedCrossRef Boffito M, Jackson A, Asboe D. Pharmacology lessons from chemoprophylaxis studies. Clin Infect Dis. 2014;59(supplement 1):S52–S4.PubMedCrossRef
21.
Zurück zum Zitat Wolf MS, Davis TC, Osborn CY, Skripkauskasa S, Bennett CL, Makoul G. Literacy, self-efficacy, and HIV medication adherence. Patient Educ Couns. 2007;65(2):253–60.PubMedCrossRef Wolf MS, Davis TC, Osborn CY, Skripkauskasa S, Bennett CL, Makoul G. Literacy, self-efficacy, and HIV medication adherence. Patient Educ Couns. 2007;65(2):253–60.PubMedCrossRef
22.
Zurück zum Zitat Lucas GM. Substance abuse, adherence with antiretroviral therapy, and clinical outcomes among HIV-infected individuals. Life Sci. 2011;88(21–22):948–52.PubMedCentralPubMedCrossRef Lucas GM. Substance abuse, adherence with antiretroviral therapy, and clinical outcomes among HIV-infected individuals. Life Sci. 2011;88(21–22):948–52.PubMedCentralPubMedCrossRef
23.
Zurück zum Zitat Pence BW. The impact of mental health and traumatic life experiences on antiretroviral treatment outcomes for people living with HIV/AIDS. J Antimicrob Chemother. 2009;63(4):636–40.PubMedCentralPubMedCrossRef Pence BW. The impact of mental health and traumatic life experiences on antiretroviral treatment outcomes for people living with HIV/AIDS. J Antimicrob Chemother. 2009;63(4):636–40.PubMedCentralPubMedCrossRef
24.
Zurück zum Zitat Weiser SD, Frongillo EA, Ragland K, Hogg RS, Riley ED, Bangsberg DR. Food insecurity is associated with incomplete HIV RNA suppression among homeless and marginally housed HIV-infected individuals in San Francisco. J Gen Intern Med. 2009;24(1):14–20.PubMedCentralPubMedCrossRef Weiser SD, Frongillo EA, Ragland K, Hogg RS, Riley ED, Bangsberg DR. Food insecurity is associated with incomplete HIV RNA suppression among homeless and marginally housed HIV-infected individuals in San Francisco. J Gen Intern Med. 2009;24(1):14–20.PubMedCentralPubMedCrossRef
25.
Zurück zum Zitat Rintamaki LS, Davis TC, Skripkauskas S, Bennett CL, Wolf MS. Social stigma concerns and HIV medication adherence. AIDS Patient Care STDs. 2006;20(5):359–68.PubMedCrossRef Rintamaki LS, Davis TC, Skripkauskas S, Bennett CL, Wolf MS. Social stigma concerns and HIV medication adherence. AIDS Patient Care STDs. 2006;20(5):359–68.PubMedCrossRef
26.
Zurück zum Zitat Tuller DM, Bangsberg D, Senkungu J, Ware NC, Emenyonu N, Weiser SD. Transportation costs impede sustained adherence and access to HAART in a clinic population in southwestern Uganda: a qualitative study. AIDS Behav. 2010;14(4):778–84.PubMedCentralPubMedCrossRef Tuller DM, Bangsberg D, Senkungu J, Ware NC, Emenyonu N, Weiser SD. Transportation costs impede sustained adherence and access to HAART in a clinic population in southwestern Uganda: a qualitative study. AIDS Behav. 2010;14(4):778–84.PubMedCentralPubMedCrossRef
27.
Zurück zum Zitat Golin CE, Liu H, Hays RD, Miller LG, Beck CK, Ickovics J, et al. A prospective study of predictors of adherence to combination antiretroviral medication. J Gen Intern Med. 2002;17(10):756–65.PubMedCentralPubMedCrossRef Golin CE, Liu H, Hays RD, Miller LG, Beck CK, Ickovics J, et al. A prospective study of predictors of adherence to combination antiretroviral medication. J Gen Intern Med. 2002;17(10):756–65.PubMedCentralPubMedCrossRef
28.
Zurück zum Zitat Simoni JM, Pearson CR, Pantalone DW, Marks G, Crepaz N. Efficacy of interventions in improving highly active antiretroviral therapy adherence and HIV-1 RNA viral load. A meta-analytic review of randomized controlled trials. JAIDS J Acquir Immune Defic Syndr. 2006;43(Supplement 1):S23–35.CrossRef Simoni JM, Pearson CR, Pantalone DW, Marks G, Crepaz N. Efficacy of interventions in improving highly active antiretroviral therapy adherence and HIV-1 RNA viral load. A meta-analytic review of randomized controlled trials. JAIDS J Acquir Immune Defic Syndr. 2006;43(Supplement 1):S23–35.CrossRef
29.
Zurück zum Zitat Amico KR, Harman J, Johnson BT. Efficacy of antiretroviral therapy adherence interventions: a research synthesis of trials, 1996 to 2004. JAIDS J Acquir Immune Defic Syndr. 2006;41(3):285–97.CrossRef Amico KR, Harman J, Johnson BT. Efficacy of antiretroviral therapy adherence interventions: a research synthesis of trials, 1996 to 2004. JAIDS J Acquir Immune Defic Syndr. 2006;41(3):285–97.CrossRef
30.
Zurück zum Zitat Chaiyachati KH, Ogbuoji O, Price M, Suthar AB, Negussie EK, Bärnighausen T (2014) Interventions to improve adherence to antiretroviral therapy: a rapid systematic review. AIDS Suppl 2:S187-204 Chaiyachati KH, Ogbuoji O, Price M, Suthar AB, Negussie EK, Bärnighausen T (2014) Interventions to improve adherence to antiretroviral therapy: a rapid systematic review. AIDS Suppl 2:S187-204
31.
Zurück zum Zitat Thompson MA, Mugavero MJ, Amico KR, Cargill VA, Chang LW, Gross R, et al. Guidelines for improving entry into and retention in care and antiretroviral adherence for persons with HIV: evidence-based recommendations from an international association of physicians in AIDS care panel. Ann Intern Med. 2012;256:817–33.CrossRef Thompson MA, Mugavero MJ, Amico KR, Cargill VA, Chang LW, Gross R, et al. Guidelines for improving entry into and retention in care and antiretroviral adherence for persons with HIV: evidence-based recommendations from an international association of physicians in AIDS care panel. Ann Intern Med. 2012;256:817–33.CrossRef
32.
Zurück zum Zitat Belzer ME, Naar-King S, Olson J, Sarr M, Thornton S, Kahana SY, et al (2013) The use of cell phone support for non-adherent HIV-infected youth and young adults: an initial randomized and controlled intervention trial. AIDS Behav Belzer ME, Naar-King S, Olson J, Sarr M, Thornton S, Kahana SY, et al (2013) The use of cell phone support for non-adherent HIV-infected youth and young adults: an initial randomized and controlled intervention trial. AIDS Behav
33.
Zurück zum Zitat Castro JG, Waldrop-Valverde D, Valverde EE (2013) An educational intervention with Hispanic HIV infected patients: a randomized study. Epidemiol 4(1). Castro JG, Waldrop-Valverde D, Valverde EE (2013) An educational intervention with Hispanic HIV infected patients: a randomized study. Epidemiol 4(1).
34.
Zurück zum Zitat Robbins GK, Testa MA, Su M, Safren SA, Morse G, Lammert S, et al. Site nurse-initiated adherence and symptom support telephone calls for HIV-positive individuals starting antiretroviral therapy, ACTG 5031: substudy of ACTG 384. HIV Clinical Trials. 2013;14(5):235–53.PubMedCentralPubMedCrossRef Robbins GK, Testa MA, Su M, Safren SA, Morse G, Lammert S, et al. Site nurse-initiated adherence and symptom support telephone calls for HIV-positive individuals starting antiretroviral therapy, ACTG 5031: substudy of ACTG 384. HIV Clinical Trials. 2013;14(5):235–53.PubMedCentralPubMedCrossRef
35.
Zurück zum Zitat Kalichman S, Cherry C, Kalichman MO, Amaral C, White D, Cruess D, et al. Randomized clinical trial of HIV treatment adherence counseling interventions for people living with HIV and limited health literacy. JAIDS J Acquir Immune Defic Syndr. 2013;63(1):42–50.CrossRef Kalichman S, Cherry C, Kalichman MO, Amaral C, White D, Cruess D, et al. Randomized clinical trial of HIV treatment adherence counseling interventions for people living with HIV and limited health literacy. JAIDS J Acquir Immune Defic Syndr. 2013;63(1):42–50.CrossRef
36.
Zurück zum Zitat Lewis MA, Uhrig JD, Bann CM, Harris JL, Furberg RD, Coomes C, et al. Tailored text messaging intervention for HIV adherence: a proof-of-concept study. Health Psychol. 2013;32(3):248–53.PubMedCrossRef Lewis MA, Uhrig JD, Bann CM, Harris JL, Furberg RD, Coomes C, et al. Tailored text messaging intervention for HIV adherence: a proof-of-concept study. Health Psychol. 2013;32(3):248–53.PubMedCrossRef
37.
Zurück zum Zitat Claborn KR, Leffingwell TR, Miller MB, Ellen Meier E, Stephens JR. Pilot study examining the efficacy of an electronic intervention to promote HIV medication adherence. AIDS Care. 2014;26(3):404–9.PubMedCrossRef Claborn KR, Leffingwell TR, Miller MB, Ellen Meier E, Stephens JR. Pilot study examining the efficacy of an electronic intervention to promote HIV medication adherence. AIDS Care. 2014;26(3):404–9.PubMedCrossRef
38.
Zurück zum Zitat Letourneau EJ, Ellis DA, Naar-King S, Chapman JE, Cunningham PB, Fowler S. Multisystemic therapy for poorly adherent youth with HIV: results from a pilot randomized controlled trial. AIDS Care. 2013;25(4):507–14.PubMedCrossRef Letourneau EJ, Ellis DA, Naar-King S, Chapman JE, Cunningham PB, Fowler S. Multisystemic therapy for poorly adherent youth with HIV: results from a pilot randomized controlled trial. AIDS Care. 2013;25(4):507–14.PubMedCrossRef
39.
Zurück zum Zitat Reznick OG, McCartney K, Gregorich SE, Zack B, Feaster DJ. An ecosystem-based intervention to reduce HIV transmission risk and increase medication adherence among inmates being released to the community. J Correct Health Care. 2013;19(3):178–93.PubMedCentralPubMedCrossRef Reznick OG, McCartney K, Gregorich SE, Zack B, Feaster DJ. An ecosystem-based intervention to reduce HIV transmission risk and increase medication adherence among inmates being released to the community. J Correct Health Care. 2013;19(3):178–93.PubMedCentralPubMedCrossRef
40.
Zurück zum Zitat Robbins RN, Mellins CA, Leu C, Rowe J, Warne P, Abrams E, et al. (2014) Enhancing lay counselor capacity to improve patient outcomes with multimedia technology. AIDS Behav. Forthcoming 2015. Robbins RN, Mellins CA, Leu C, Rowe J, Warne P, Abrams E, et al. (2014) Enhancing lay counselor capacity to improve patient outcomes with multimedia technology. AIDS Behav. Forthcoming 2015.
41.
Zurück zum Zitat Bhana A, Mellins CA, Petersen I, Alicea S, Myeza N, Holst H, et al. The VUKA family program: piloting a family-based psychosocial intervention to promote health and mental health among HIV infected early adolescents in South Africa. AIDS Care. 2014;26(1):1–11.PubMedCrossRef Bhana A, Mellins CA, Petersen I, Alicea S, Myeza N, Holst H, et al. The VUKA family program: piloting a family-based psychosocial intervention to promote health and mental health among HIV infected early adolescents in South Africa. AIDS Care. 2014;26(1):1–11.PubMedCrossRef
42.
Zurück zum Zitat Jones D, Bofil L, Aristegui I, Mattioli I, Ceccini D, Sued O, et al. (eds) (2014) COPA: Enhancing adherence, engagement, and retention in HIV Care in Argentina. 9th International Conference on HIV treatment and Prevention Adherence. Miami, Fl. Jones D, Bofil L, Aristegui I, Mattioli I, Ceccini D, Sued O, et al. (eds) (2014) COPA: Enhancing adherence, engagement, and retention in HIV Care in Argentina. 9th International Conference on HIV treatment and Prevention Adherence. Miami, Fl.
43.
Zurück zum Zitat Enriquez M, Hart K (eds) (2014) "Someone to Listen": Becoming adherent to HIV medication after repeated failure. 9th International Conference on HIV Treatment and Prevention Adherence. Miami, Fl. Enriquez M, Hart K (eds) (2014) "Someone to Listen": Becoming adherent to HIV medication after repeated failure. 9th International Conference on HIV Treatment and Prevention Adherence. Miami, Fl.
44.
Zurück zum Zitat van der Straten A, Mayo A, Brown E, Amico KR, Cheng H, Laborde N, et al. (eds) (2014) Assessment of VOICE adherence support program (VASP) in the MTN-003 Trial. 9th International Conference on HIV treatment and Prevention Adherence. Miami, Fl. van der Straten A, Mayo A, Brown E, Amico KR, Cheng H, Laborde N, et al. (eds) (2014) Assessment of VOICE adherence support program (VASP) in the MTN-003 Trial. 9th International Conference on HIV treatment and Prevention Adherence. Miami, Fl.
45.
Zurück zum Zitat Rana A, van den Berg J, Lamy E, Beckwith CG (eds) (2014) Piloting an mHealth intervention to improve treatment adherence among newly diagnosed and non-adherent HIV positive patients. 9th International Conference on HIV treatment and Prevention Adherence. Miami, Fl. Rana A, van den Berg J, Lamy E, Beckwith CG (eds) (2014) Piloting an mHealth intervention to improve treatment adherence among newly diagnosed and non-adherent HIV positive patients. 9th International Conference on HIV treatment and Prevention Adherence. Miami, Fl.
46.
Zurück zum Zitat Ingersoll K, Dillingham R, Reynolds G, Freeman J, Hosseinbor A, Hettema J (eds) (2014) Feasibility and impact of a personalized bidirectional text messaging ART adherence tool for nonurban substance users. 9th International Conference on HIV treatment and Prevention Adherence. Miami, Fl. Ingersoll K, Dillingham R, Reynolds G, Freeman J, Hosseinbor A, Hettema J (eds) (2014) Feasibility and impact of a personalized bidirectional text messaging ART adherence tool for nonurban substance users. 9th International Conference on HIV treatment and Prevention Adherence. Miami, Fl.
47.
Zurück zum Zitat Dennis D, Abrams L, Morey T, Melker R (eds) (2014) Usability evaluation of SMART adherence system in HIV-positive patients. 9th International Conference on HIV treatment and Prevention Adherence. Miami, Fl. Dennis D, Abrams L, Morey T, Melker R (eds) (2014) Usability evaluation of SMART adherence system in HIV-positive patients. 9th International Conference on HIV treatment and Prevention Adherence. Miami, Fl.
48.
Zurück zum Zitat Schneider MP, Rotzinger A, Maestralli D, Bugnon O, Cavassini M, Parienti JJ. Adherence-enhancing program and retention to care in the Swiss Cohort. 9th International Conference on HIV Treatment and Prevention Adherence. Miami, Fl; 2014. Schneider MP, Rotzinger A, Maestralli D, Bugnon O, Cavassini M, Parienti JJ. Adherence-enhancing program and retention to care in the Swiss Cohort. 9th International Conference on HIV Treatment and Prevention Adherence. Miami, Fl; 2014.
49.
Zurück zum Zitat Sevelius J, Johnson M, Saberi P (eds) (2014) Health Divas: a culturally relevant intervention to improve engagement in care among transgender women living with HIV. 9th International Conference on HIV treatment and Prevention Adherence. Miami, Fl. Sevelius J, Johnson M, Saberi P (eds) (2014) Health Divas: a culturally relevant intervention to improve engagement in care among transgender women living with HIV. 9th International Conference on HIV treatment and Prevention Adherence. Miami, Fl.
50.
Zurück zum Zitat Teti M, Gerkovich M, Farnan R. Snapshots of adherence: photo-stories as a tool to promote medication use among people with HIV. 9th International Conference on HIV Treatment and Prevention Adherence. Miami, Fl; 2014. Teti M, Gerkovich M, Farnan R. Snapshots of adherence: photo-stories as a tool to promote medication use among people with HIV. 9th International Conference on HIV Treatment and Prevention Adherence. Miami, Fl; 2014.
51.
Zurück zum Zitat Lehrman S, Evans E, Brady K, Terrell C (eds) (2014) Early results from the Philadelphia Integrative Behavioral Health Initiative: Improved Retention in Care. 9th International Conference on HIV treatment and Prevention Adherence. Miami, Fl. Lehrman S, Evans E, Brady K, Terrell C (eds) (2014) Early results from the Philadelphia Integrative Behavioral Health Initiative: Improved Retention in Care. 9th International Conference on HIV treatment and Prevention Adherence. Miami, Fl.
52.
Zurück zum Zitat Green K, Jones R, Ortiz-Ricard A (eds) (2014) Updating the evidence-based intervention pager messaging into a mobile application to improve adherence to antiretroviral treatment. 9th International Conference on HIV treatment and Prevention Adherence. Miami, Fl. Green K, Jones R, Ortiz-Ricard A (eds) (2014) Updating the evidence-based intervention pager messaging into a mobile application to improve adherence to antiretroviral treatment. 9th International Conference on HIV treatment and Prevention Adherence. Miami, Fl.
53.
Zurück zum Zitat Gross R, Zheng L, La Rosa A, Sun X, Rosenkranz S, Cardoso-Wagner S, et al. (eds) (2014) Partner-based intervention for adherence to second-line ART: a multinational trial (ACTG A5234). 2014 Conference on Retroviruses and Opportunistic Infections. Boston, Mass. Gross R, Zheng L, La Rosa A, Sun X, Rosenkranz S, Cardoso-Wagner S, et al. (eds) (2014) Partner-based intervention for adherence to second-line ART: a multinational trial (ACTG A5234). 2014 Conference on Retroviruses and Opportunistic Infections. Boston, Mass.
54.
Zurück zum Zitat Simoni JM, Wiebe JS, Sauceda JA, Huh D, Sanchez G, Longoria V, et al. A preliminary RCT of CBT-AD for adherence and depression among HIV-positive Latinos on the US-Mexico border: the Nuevo Dia study. AIDS Behav. 2013;17(8):2816–29.PubMedCentralPubMedCrossRef Simoni JM, Wiebe JS, Sauceda JA, Huh D, Sanchez G, Longoria V, et al. A preliminary RCT of CBT-AD for adherence and depression among HIV-positive Latinos on the US-Mexico border: the Nuevo Dia study. AIDS Behav. 2013;17(8):2816–29.PubMedCentralPubMedCrossRef
57.
Zurück zum Zitat Ellis DA, Naar-King S, Cunningham PB, Secord E. Use of multisystemic therapy to improve antiretroviral adherence and health outcomes in HIV-infected pediatric patients: evaluation of a pilot program. AIDS Patient Care STDs. 2006;20(2):112–21.PubMedCrossRef Ellis DA, Naar-King S, Cunningham PB, Secord E. Use of multisystemic therapy to improve antiretroviral adherence and health outcomes in HIV-infected pediatric patients: evaluation of a pilot program. AIDS Patient Care STDs. 2006;20(2):112–21.PubMedCrossRef
58.
Zurück zum Zitat McKay MM, Chase K, Baptiste D, Bell C, Coleman D, Madision S, et al. Family-level impact of the CHAMP family program: a community collaborative effort to support urban families and reduce youth HIV risk exposure. Fam Process. 2004;77:77–91. McKay MM, Chase K, Baptiste D, Bell C, Coleman D, Madision S, et al. Family-level impact of the CHAMP family program: a community collaborative effort to support urban families and reduce youth HIV risk exposure. Fam Process. 2004;77:77–91.
59.
Zurück zum Zitat Petersen I, Bhana A, Baillie K (2011) The feasibility of adapted group-based interpersonal therapy (IPT) for the treatment of depression by community health workers within the context of task shifting in South Africa. Commun Mental Health J:1–6. Petersen I, Bhana A, Baillie K (2011) The feasibility of adapted group-based interpersonal therapy (IPT) for the treatment of depression by community health workers within the context of task shifting in South Africa. Commun Mental Health J:1–6.
60.
Zurück zum Zitat Bosworth K, Espelage D, DuBay T, Daytner G, Karageorge K. Preliminary evaluation of a multimedia violence prevention program for adolescents. Am J Health Behav. 2000;24:268–80.CrossRef Bosworth K, Espelage D, DuBay T, Daytner G, Karageorge K. Preliminary evaluation of a multimedia violence prevention program for adolescents. Am J Health Behav. 2000;24:268–80.CrossRef
61.
Zurück zum Zitat Bartholomew LK, Shegog R, Parcel GS, et al. Watch, discover, think, and act: a model for patient education program development. Patient Educ Couns. 2000;39(2):253–68.PubMedCrossRef Bartholomew LK, Shegog R, Parcel GS, et al. Watch, discover, think, and act: a model for patient education program development. Patient Educ Couns. 2000;39(2):253–68.PubMedCrossRef
62.
Zurück zum Zitat Rubin DH, Leventhal JM, Sadock RT, et al. Educational intervention by computer in childhood asthma: a randomized clinical trial testing the use of a new teaching intervention in childhood asthma. Pediatrics. 1986;77:1–10.PubMed Rubin DH, Leventhal JM, Sadock RT, et al. Educational intervention by computer in childhood asthma: a randomized clinical trial testing the use of a new teaching intervention in childhood asthma. Pediatrics. 1986;77:1–10.PubMed
63.
Zurück zum Zitat Brown SJ, Lieberman DA, Gemeny BA, Fan YC, Wilson DM, Pasta DJ. Educational video game for juvenile diabetes: results of a controlled trial. Med Inform (Lond). 1997;22:77–89.CrossRef Brown SJ, Lieberman DA, Gemeny BA, Fan YC, Wilson DM, Pasta DJ. Educational video game for juvenile diabetes: results of a controlled trial. Med Inform (Lond). 1997;22:77–89.CrossRef
64.
Zurück zum Zitat French D. Influence smoking cessation with computer-assisted instruction. AAOHN. 1986;34:391–4. French D. Influence smoking cessation with computer-assisted instruction. AAOHN. 1986;34:391–4.
65.
Zurück zum Zitat Tingen MS, Grimling LF, Bennet G, Gibson EM, Renew MM. A pilot study of preadolescents to evaluate a video game-based smoking prevention strategy. J Addict Nurs. 1997;9:118–24.CrossRef Tingen MS, Grimling LF, Bennet G, Gibson EM, Renew MM. A pilot study of preadolescents to evaluate a video game-based smoking prevention strategy. J Addict Nurs. 1997;9:118–24.CrossRef
66.
Zurück zum Zitat Reis J, Riley W, Baer J. Interactive multimedia preventive alcohol education: an evaluation of effectiveness with college students. J Educ Comput Res. 2000;23:41–65.CrossRef Reis J, Riley W, Baer J. Interactive multimedia preventive alcohol education: an evaluation of effectiveness with college students. J Educ Comput Res. 2000;23:41–65.CrossRef
67.
Zurück zum Zitat Safren S, Otto MW, Worth JL, Salomon E, Johnson W, Mayer K, et al. Two strategies to increase adherence to HIV antiretroviral medication: life-steps and medication monitoring. Behav Re Ther. 2001;39(10):1151–62.CrossRef Safren S, Otto MW, Worth JL, Salomon E, Johnson W, Mayer K, et al. Two strategies to increase adherence to HIV antiretroviral medication: life-steps and medication monitoring. Behav Re Ther. 2001;39(10):1151–62.CrossRef
68.
Zurück zum Zitat Remien RH, Mellins CA, Robbins RN, Kelsey R, Rowe J, Warne P, et al. Masivukeni: development of a multimedia based antiretroviral therapy adherence intervention for counselors and patients in South Africa. AIDS Behav. 2013;17(6):1979–91.PubMedCentralPubMedCrossRef Remien RH, Mellins CA, Robbins RN, Kelsey R, Rowe J, Warne P, et al. Masivukeni: development of a multimedia based antiretroviral therapy adherence intervention for counselors and patients in South Africa. AIDS Behav. 2013;17(6):1979–91.PubMedCentralPubMedCrossRef
69.
Zurück zum Zitat Remien RH, Stirratt MJ, Dognin J, Day E, El-Bassel N, Warne P. Moving from theory to research to practice. Implementing an effective dyadic intervention to improve antiretroviral adherence for clinic patients. J Acquir Immune Defic Syndr. 2006;43 Suppl 1:S68–78. Remien RH, Stirratt MJ, Dognin J, Day E, El-Bassel N, Warne P. Moving from theory to research to practice. Implementing an effective dyadic intervention to improve antiretroviral adherence for clinic patients. J Acquir Immune Defic Syndr. 2006;43 Suppl 1:S68–78.
70.
Zurück zum Zitat Remien RH, Mellins C (2007) Long-term psychosocial challenges for people living with HIV: let’s not forget the individual in our global response to the pandemic. AIDS Supplement 5:S55-63. Remien RH, Mellins C (2007) Long-term psychosocial challenges for people living with HIV: let’s not forget the individual in our global response to the pandemic. AIDS Supplement 5:S55-63.
71.
Zurück zum Zitat Remien R, Hirky E, Johnson MO, Weinhardt LS, Whittier D, Le GM. Adherence to medication treatment: facilitators and barriers among a diverse sample of HIV+ men and women in four U.S. Cities. AIDS Behav. 2003;7(1):61–72.PubMedCrossRef Remien R, Hirky E, Johnson MO, Weinhardt LS, Whittier D, Le GM. Adherence to medication treatment: facilitators and barriers among a diverse sample of HIV+ men and women in four U.S. Cities. AIDS Behav. 2003;7(1):61–72.PubMedCrossRef
72.
Zurück zum Zitat de Bruin M, Viechtbauer W, Schaalma HP, Kok G, Abraham C, Hospers HJ. Standard care impact on effects of highly active antiretroviral therapy adherence interventions: A meta-analysis of randomized controlled trials. Arch Intern Med. 2010;170(3):240–50.PubMedCrossRef de Bruin M, Viechtbauer W, Schaalma HP, Kok G, Abraham C, Hospers HJ. Standard care impact on effects of highly active antiretroviral therapy adherence interventions: A meta-analysis of randomized controlled trials. Arch Intern Med. 2010;170(3):240–50.PubMedCrossRef
73.
Zurück zum Zitat Wagner GJ, Kanouse DE. Assessing usual care in clinical trials of adherence interventions for highly active antiretroviral therapy. JAIDS J Acquir Immune Defic Syndr. 2003;33(2):276–77.CrossRef Wagner GJ, Kanouse DE. Assessing usual care in clinical trials of adherence interventions for highly active antiretroviral therapy. JAIDS J Acquir Immune Defic Syndr. 2003;33(2):276–77.CrossRef
74.
Zurück zum Zitat Safren S, O’Cleirigh C, Bullis J. CBT for adherence and depression (CBT-AD) in HIV-infected injection drug users: an RCT. J Consult Clin Psychol. 2011;80(3):404–15.CrossRef Safren S, O’Cleirigh C, Bullis J. CBT for adherence and depression (CBT-AD) in HIV-infected injection drug users: an RCT. J Consult Clin Psychol. 2011;80(3):404–15.CrossRef
75.
Zurück zum Zitat Safren SA, O’Cleirigh CM, Bullis JR, Otto MW, Stein MD, Pollack MH. Cognitive behavioral therapy for adherence and depression (CBT-AD) in HIV-infected injection drug users: a randomized controlled trial. J Consult Clin Psychol. 2012;80(3):404.PubMedCentralPubMedCrossRef Safren SA, O’Cleirigh CM, Bullis JR, Otto MW, Stein MD, Pollack MH. Cognitive behavioral therapy for adherence and depression (CBT-AD) in HIV-infected injection drug users: a randomized controlled trial. J Consult Clin Psychol. 2012;80(3):404.PubMedCentralPubMedCrossRef
76.
Zurück zum Zitat Safren S, O’Cleirigh CM, Tan J, et al. A randomized controlled trial of cognitive behavioral therapy for adherence and depression (CBT-AD) in HIV-infected individuals. Health Psychol. 2009;28(1):1–10.PubMedCentralPubMedCrossRef Safren S, O’Cleirigh CM, Tan J, et al. A randomized controlled trial of cognitive behavioral therapy for adherence and depression (CBT-AD) in HIV-infected individuals. Health Psychol. 2009;28(1):1–10.PubMedCentralPubMedCrossRef
Metadaten
Titel
Optimizing ART Adherence: Update for HIV Treatment and Prevention
verfasst von
Reuben N. Robbins
Anya Y. Spector
Claude A. Mellins
Robert H. Remien
Publikationsdatum
01.12.2014
Verlag
Springer US
Erschienen in
Current HIV/AIDS Reports / Ausgabe 4/2014
Print ISSN: 1548-3568
Elektronische ISSN: 1548-3576
DOI
https://doi.org/10.1007/s11904-014-0229-5

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