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Erschienen in: Current Hypertension Reports 5/2015

01.05.2015 | Hypertension and Obesity (E Reisin, Section Editor)

Cardiovascular and Renal Effects of Weight Reduction in Obesity and the Metabolic Syndrome

verfasst von: Jordana B. Cohen, Debbie L. Cohen

Erschienen in: Current Hypertension Reports | Ausgabe 5/2015

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Abstract

Obesity is a critical public health issue worldwide. Patients with obesity have markedly increased morbidity and mortality compared to the general population. The increased health risks of obesity in part are due to its close association with each of the other components of the metabolic syndrome, including hypertension, dyslipidemia, and insulin resistance. Accordingly, obese individuals are at particularly increased risk of cardiovascular disease and chronic kidney disease. Modest weight loss results in improvements in serum cholesterol levels, blood pressure, and glycemic profiles. Lifestyle interventions for weight loss have long been the mainstay of treatment in obesity. However, the existing literature demonstrates limited weight loss sustainability and inconsistent cardiovascular and renal benefits using these modalities. In addition to improvements in intermediate risk factors, surgical interventions provide a more lasting impact on long-term cardiovascular and renal outcomes, though carry higher short-term risks due to perioperative complications.
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Metadaten
Titel
Cardiovascular and Renal Effects of Weight Reduction in Obesity and the Metabolic Syndrome
verfasst von
Jordana B. Cohen
Debbie L. Cohen
Publikationsdatum
01.05.2015
Verlag
Springer US
Erschienen in
Current Hypertension Reports / Ausgabe 5/2015
Print ISSN: 1522-6417
Elektronische ISSN: 1534-3111
DOI
https://doi.org/10.1007/s11906-015-0544-2

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