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Current Neurology and Neuroscience Reports
Erschienen in: Current Neurology and Neuroscience Reports 6/2012

01.12.2012 | Infection (B Jubelt, Section Editor)

Tetanus in Ethiopia: Unveiling the Blight of an Entirely Vaccine-Preventable Disease

verfasst von: Yohannes Woubishet Woldeamanuel

Erschienen in: Current Neurology and Neuroscience Reports | Ausgabe 6/2012

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Abstract

Today, tetanus exacts its toll only in resource-poor countries like Ethiopia. Agrarian rural life with limited vaccine typifies tetanus risk in Ethiopia where current tetanus control trends on expanding infant immunization and eliminating highly prevalent maternal and neonatal tetanus (MNT). Protection by infant tetanus immunization primers disappears within an average of 3 years, if not followed by boosters. Second-year of life, school-based, and universal 10-yearly tetanus immunizations need to be supplemented. Facility-based reviews in Ethiopia reveal a continued burden of tetanus at tertiary-level hospitals where ICU care is suboptimal. Quality of medical care for tetanus is low - reflected by high case-fatality-rates. Opportunities at primary-health-care-units (antenatal-care, family planning, abortion, wound-care, tetanus-survivors) need to be fully-utilized to expand tetanus immunization. Prompt wound-care with post-exposure prophylaxis and proper footwear must be promoted. Standard ICU care needs to exist. Realization of cold-chain-flexible, needle-less and mono-dose vaccine programs allow avoiding boosters, vaccine-refrigeration, and improve compliance.
Literatur
1.
2.
•• Central Statisitcal Agency, A.A., Ethiopia, Ethiopia Demographic and Health Survey, 2012. This report provides the most recent and the largest community-based data summary on immunization and related indicators in Ethiopia. It gives a comprehensive review of health and demographic indicators that can be accessed by multitude of sectors.
3.
WHO, The global burden of disease. 2004; update, 2008.
4.
•• Amare A, Melkamu Y, Mekonnen D. Tetanus in adults: clinical presentation, treatment and predictors of mortality in a tertiary hospital in Ethiopia. J Neurol Sci. 2012;317:62–5. This recent study provides a retrospective analysis of 68 tetanus patients admitted from 2001–2009 to the highest referral specialized hospital in Ethiopia - the Black Lion Hospital. It has a comprehensive description of clinical forms of disease, treatment modalities, rates, and predictors of fatality, and relevant recommendations. PubMedCrossRef
5.
Tadesse H, Deribew A, Woldie M. Predictors of defaulting from completion of child immunization in south Ethiopia, May 2008–a case control study. BMC Publ Health. 2009;9:150.CrossRef
6.
Woldeamanuel YW, Hassan A. Tetanus weighs on neurological burden in Ethiopia. World Neurol. 2010;25:14.
7.
Amare A, Yami A. Case-fatality of adult Tetanus at Jimma University Teaching Hospital, Southwest Ethiopia. Afr Health Sci. 2011;11:36–40.PubMed
8.
Worku T, Bayou A, Aseffa A. Tetanus in a rural hospital in Northeast Ethiopia. Ethiopian J Health Dev. 2004;18:55–6.
9.
Amsalu S, Lulseged S. Tetanus in a children's hospital in Addis Ababa: review of 113 cases. Ethiopia Med J. 2005;43:233–40.
10.
Hodes RM, Teferedegne B. Tetanus in Ethiopia: analysis of 55 cases from Addis Ababa. East Afr Med J. 1990;67:887–93.PubMed
11.
Nida H. Neonatal tetanus in Awassa: retrospective analysis of patients admitted over 5 years. Ethiopia Med J. 2001;39:241–6.
12.
Ogunrin O. Tetanus–a review of current concepts in management. J Postgrad Med. 2009;11:46–61.
13.
Atkinson W, Wolfe C, Hamborsk J, editors. Tetanus, in epidemiology and prevention of vaccine-preventable diseases. Washington: Public Health Foundation; 2011. p. 291–300.
14.
Cherry J, Harrison R. Tetanus. In: Feigin RD, Cherry J, Demmler-Harrison GJ, Kaplan SL, editors. Textbook of pediatric infectious diseases. Philadelphia: Elsevier; 2004. p. 1766–76.
15.
Bleck T. Clostridium tetani. In: Mandell GL, Bennett JE, Dolin R, editors. Bennett's principles and practice of infectious diseases. Philadelphia: Churchill Livingstone; 1995. 9-p. 2373–8.
16.
Alene G. Harmful traditional health practices: a cross-sectional survey among under-five children in Dembia district, north-west Ethiopia. Ethiopia J Health Biomed Sci. 2010;2:83–93.
17.
WHO. Podoconiosis: endemic non-filarial elephantiasis. 2012 (cited 2012 29/05/12).
18.
Simmonsen O, Block A, Heron I. Epidemiology of tetanus in Denmark 1920–1982. Scand J Infect Dis. 1987;19:437–44.CrossRef
19.
20.
21.
22.
23.
24.
25.
Kidane T, Yigzaw A, Sahilemariam Y, Bulto T, Mengistu H, Belay T, et al. National EPI coverage survey report in Ethiopia, 2006. Ethiopia J Health Dev. 2008;22:148–57.
26.
27.
28.
29.
30.
Using early childhood booster doses to maintain the elimination of Neonatal Tetanus. Steinglass R. Based on a paper delivered at the World Health Organization (WHO) Neonatal Tetanus Elimination Technical Consultation, Geneva, 1997. Available at: pdf.​usaid.​gov/​pdf_​docs/​PNACN105.​pdf. Accessed June 16, 2012.
31.
Galazka A. The immunological basis for immunization. Module 3: tetanus. Global programme for vaccines and immunization. Geneva: Expanded Programme on Immunization; 1996.
32.
Naimoli JF, Challa S, Schneidman M, Kostermans K. Toward a grounded theory of why some immunization programs in sub-Saharan Africa are more successful than others: a descriptive and exploratory assessment in 6 countries. Health Policy Plann. 2008:23:379–89.
33.
England S. “The evidence base for interventions to reduce mortality from vaccine-preventable diseases in low and middle-income Countries” (Geneva: Commission on Macroeconomics and Health, Working Paper Series, June 5, 2001) 2001.
34.
Bloom D, Canning D, Weston M. The value of vaccination. World Econ. 2004;6:15–39.
35.
Miguel E, Kremer M. Worms: identifying impacts on education and health the presence of treatment externalities. Econometrica. 2004;72:159–217.CrossRef
36.
Bawah AA, Phillips JF, Adjuik M, Vaughan-Smith M, Macleod B, Binka FN. The impact of immunization on the association between poverty and child survival: evidence from Kassena-Nankana District of northern Ghana. Scand J Publ Health. 2010;38:95–103.
37.
Mekonen Y. Missed opportunity of tetanus toxoid immunization among pregnant women in Southern Ethiopia. Ethiopian J Health Dev. 2000;14:143–8.
38.
WHO. Tetanus vaccine: WHO position paper. Wkly Epidemiol Rec. 2006;81:198–208.
39.
40.
Maru M, Getahun A, Hosana S. A house-to-house survey of neonatal tetanus in urban and rural areas in the Gondar region, Ethiopia. Trop Geogr Med. 1988;40:233–6.PubMed
41.
42.
Kidane T. Factors influencing TT immunization coverage and protection at birth coverage in Tselemi District, Ethiopia. Ethiopia J Health Dev. 2004;18:153–8.
43.
Steinglass R. Eliminating neonatal tetanus, excerpted from basic support for institutionalizing child survival project (BASICS II) for the United States Agency for International Development. Arlington, Virginia, June 2001.
44.
Ramos JM, Reyes F, Tesfamariam A. Tetanus in a rural Ethiopian hospital. Trop Doct. 2008;38:104–5.PubMedCrossRef
45.
Habte-Gabr E, Mengistu M. Tetanus in Gondar Public Health College Hospital, Ethiopia: a review of 72 cases. Ethiopia Med J. 1978;16:53–61.
46.
Black RE, Cousens S, Johnson HL, Lawn JE, Rudan I, Bassani DG, et al. Global, regional, and national causes of child mortality in 2008: a systematic analysis. Lancet (online). 2010;375:1969–87.CrossRef
47.
48.
Stanfield J, Galazka A. Neonatal tetanus in the world today. Bull World Health Organ. 1984;62:647–69.PubMed
49.
Meegan ME, Conroy RM, Lengeny SO, Renhault K, Nyangole J. Effect on neonatal tetanus mortality after a culturally-based health promotion programme. Lancet. 2001;358:640–1.PubMedCrossRef
50.
Vandelaer J, Birmingham M, Gasse F, Kurian M, Shaw C, Garnier S. Tetanus in developing countries: an update on the maternal and neonatal tetanus elimination initiative. Vaccine. 2003;21:3442–5.
51.
Brenzel L, Wolfson LJ, Fox-Rushby J, Miller M, Halsey NA. Vaccine-preventable disease. In: Jamison D, Breman J, Measham J, editors. Disease control priorities in developing countries. New York: Oxford University Press; 2006. p. 389–411.
52.
Laxminarayan R, Mills AJ, Breman JG, Measham AR, Alleyne G, Claeson M, et al. Advancement of global health: key messages from the Disease Control Priorities Project. Lancet. 2006;367:1193–208.PubMedCrossRef
53.
54.
55.
56.
Pascual FB, McGinley EL, Zanardi LR, Cortese MM, Murphy TV. Tetanus surveillance - United States. MMWR Surveill Summ. 2003;52:1–8.PubMed
57.
Wassila S, et al. Tetanus toxoid. In: Plotkin S, Orenstein W, Offit P, editors. Vaccines. Philadelphia: Saunders; 2008. p. 805–39.
58.
Deressa W, Ali A. Malaria-related perceptions and practices of women with children under the age of five years in rural Ethiopia. BMC Publ Health. 2009;9:259.
59.
Hadgu P, Tsega E, Geremew S. Tetanus: review of the literature and outline of prophylaxis and management. Ethiopia Med J. 1975;1:161–70.
60.
Brabin BJ, Nagel J, Hagenaars AM, Ruitenberg E, van Tilborgh AM. The influence of malaria and gestation on the immune response to one and two doses of adsorbed tetanus toxoid in pregnancy. Bull, Geneva, World Health Organ. 1984;62:919–30.
61.
62.
63.
Blanche S, Le Deist F, Fischer A, Veber F, Debre M, Chamaret S, et al. Longitudinal study of 18 children with perinatal LAV/HTLV infection: attempt at prognostic evaluation. J Pediatr. 1986;109:965–70.
64.
Kurtzhals JA, Kjeldsen K, Heron I, Skinhøj P. Immunity against diphtheria and tetanus in human immunodeficiency virus -infected Danish men born 1950–1959. APMIS. 1992;100:803–8.PubMedCrossRef
65.
Kroon F. Immunoglobulin (IgG) subclass distribution and IgG1 avidity of antibodies in human immunodeficiency virus-infected individuals after revaccination with tetanus toxoid. Clin Diagn Lab Immunol. 1999;6:352–5.PubMed
66.
Moss WJ, Clements CJ, Halsey NA. Immunization of children at risk of infection with human immunodeficiency virus. Bulletin, Geneva, World Health. Organization. 2003;81:6170.
67.
de Moraes-Pinto MI, Almeida AC, Kenj G, Filgueiras TE, Tobias W, Santos AM, et al. Placental transfer and maternally acquired neonatal IgG immunity in human immunodeficiency virus infection. J Infect Dis. 1996;173:1077–84.
68.
Okoko J, Wesumperuma H, Hart C. The influence of prematurity and low birthweight on transplacental antibody transfer in a rural west African population. Trop Med Int Health. 2001;6:529–34.PubMedCrossRef
69.
de Moraes-Pinto MI, Verhoeff F, Chimsuku L, Milligan PJ, Wesumperuma L, Broadhead RL, et al. Placental antibody transfer: influence of maternal HIV infection and placental malaria. Arch Dis Child Fetal Neonatal Ed. 1998;79:202–5.
70.
Okoko BJ, Wesuperuma LH, Ota MO, Banya WA, Pinder M, Gomez FS, et al. Influence of palcental malaria infection and maternal hypergammaglobulinema on materno-foetal transfer of measles and tetanus antibodies in a rural west African population. J Health Popul Nutr. 2001;19:59–65.
71.
72.
Hodes R, Teferedegne B. Tetanus in leprosy patients: report of five cases. Int J Lepr Other Mycobact Dis. 1988;56:228–30.PubMed
73.
Singh M, Kumar B, Ayagiri A, Kaur S. Natural tetanus immunity in lepromatous leprosy patients. Indian J Lepr. 1986;58:91–5.PubMed
74.
Dharmendra SH. Leprosy. Bombay: Kothari Publishing House; 1978. p. I.
75.
Goodwin D, Wood M. Bacteria isolated from plantar ulcers of Ethiopian leprosy patients with antibacterial drug sensitivities of the isolates. Trans R Soc Trop Med Hyg. 1970;64:421–6.PubMedCrossRef
76.
Guilfoile P. Deadly diseases and epidemics: tetanus. In: Babock H, editor. Deadly diseases and epidemics. New York: Infobase Publishing; 2008. p. 100.
77.
Berger SA, Cherubin CE, Nelson S, Levine L. Tetanus despite preexisting antitetanus antibody. JAMA. 1978;240:769–70.PubMedCrossRef
78.
Goulon M, Girard O, Grosbuis S, Desormeau JP, Capponi MF. [Les anticorps antitetaniques. Titrage avant seroanatoxiono-therapie chez 64 tetaniques]. Nouv Presse Med. 1972;1:3049–50.PubMed
79.
Passen E, Andersen B. Clinical tetanus despite a “protective” level of toxin-neutralizing antibody. JAMA. 1986;255:1171–3.PubMedCrossRef
80.
Matzkin H, Regev S. Naturally acquired immunity to tetanus in an isolated community. Infect Immun. 1985;48:267–8.PubMed
81.
Ray SN, Ray K, Grover SS, Sharma RS, Sharma SP. Sero-survey of diphtheria and tetanus antitoxin. Indian J Med Res. 1978;68:901–4.PubMed
82.
Veronesi R, Cecin H, Corrêa A, Tavares J, Moraes C, Bertoldo OJ. New concepts in tetanus immunization: naturally acquired immunity. J Hyg Epidemiol Microbiol Immunol. 1975;19:126–34.
83.
Veronesi R, Bizzini B, Focaccia R, Coscina AL, Mazza CC, Focaccia MT, et al. Naturally acquired antibodies to tetanus toxin in humans and animals from Galapagos Islands. J Infect Dis. 1983;147:308–11.
84.
Dastur FD, Awatramani VP, Dixit SK, D'Sa JA, Cooverji ND, Anand MP. Response to single dose of tetanus vaccine in subjects with naturally acquired tetanus antitoxin. Lancet. 1981;2:219–22.
85.
MacLennan R, Schofield FD, Pittman M, Hardegree MC, Barile MF. Immunization against neonatal tetanus in New Guinea: antitoxin response of pregnant women to adjuvant and plain toxoids. Bull, Geneva, World Health Organ. 1965;32:683–97.
86.
Breman JG, Wright GG, Levine L, Latham WC, Compaoré KP. The primary serological response to a single dose of adsorbed tetanus toxoid, high concentration type. Bull, Geneva, World Health Organ. 1981;59:745–52.
87.
Menon PS, Sahai G, Joshi VB, Murthy RG, Boparai MS, Thomas AK. Field trial on frozen and thawed tetanus toxoid. Indian J Med Res. 1976;64:25–32.
88.
Borrow R, Balmer P, Roper M. The immunological basis for immunization series. Module 3: tetanus. Geneva, Switzerland: WHO Document Production Services. 2006.
89.
Trujillo MH, Castillo A, España J, Manzo A, Zerpa R. Impact of intensive care management on prognosis of tetanus: analysis of 641 cases. Chest. 1987;92:63–5.PubMedCrossRef
90.
Melaku Z, Alemayehu M, Oli K, Tizazu G. Pattern of admissions to the medical intensive care unit of Addis Ababa University Teaching Hospital. Ethiopia Med J. 2006;44:33–42.
91.
Afshar M, Raju M, Ansell D, Bleck TP. Narrative review: tetanus-a health threat after natural disasters in developing countries. Ann Intern Med. 2011;154:329–35.PubMed
92.
Shibuya M, Sugimoto H, Sugimoto T, Shimazu T, Uenishi M, Yoshioka T. The use of continuous spinal anesthesia in severe tetanus with autonomic disturbance. J Trauma. 1989;29:1423–9.
93.
Vassa NT, Doshi HV, Yajnik VH, Shah SS, Joshi KR, Patel SH. Comparative clinical trial of diazepam with other conventional drugs in tetanus. Postgrad Med J. 1974;50:755–8.
94.
Saissy JM, Demazière J, Vitris M, Seck M, Marcoux L, Gaye M, et al. Treatment of severe tetanus by intrathecal injections of baclofen without artificial ventilation. Intensive Care Med. 1992;18:241–4.
95.
Engrand N, Guerot E, Rouamba A, Vilain G. The efficacy of intrathecal baclofen in severe tetanus. Anesthesiology. 1999;90:1773–6.PubMedCrossRef
96.
Salimpour R. Tetanus of the newborn in Tehran. A ten year study of 880 cases. J Trop Pediatr Environ Child Health. 1978;24:140–2.PubMed
97.
Ertem M, Cakmak A, Saka G, Ceylan A. Neonatal tetanus in the South-Eastern region of Turkey: changes in prognostic aspects by better health care. J Trop Pediatr Environ Child Health. 2004;50:297–300.
98.
Thwaites CL, Yen LM, Loan HT, Thuy TT, Thwaites GE, Stepniewska K, et al. Magnesium sulphate for treatment of severe tetanus: a randomised controlled trial. Lancet. 2006;368:1436–43.
99.
King W, Cave D. Use of esmolol to control autonomic instability of tetanus. Am J Med. 1991;91:425–8.PubMedCrossRef
100.
Sutton DN, Tremlett MR, Woodcock TE, Nielsen MS. Management of autonomic dysfunction in severe tetanus: the use of magnesium sulphate and clonidine. Intensive Care Med. 1990;16:75–80.PubMedCrossRef
101.
Buchanan N, Cane RD, Wolfson G, De Andrade M. Autonomic dysfunction in tetanus: the effects of a variety of therapeutic agents, with special reference to morphine. Intensive Care Med. 1979;5:65–8.PubMedCrossRef
102.
103.
Wright DK, Lalloo UG, Nayiager S, Govender P. Autonomic nervous system dysfunction in severe tetanus: current perspectives. Crit Care Med. 1989;17:371–5.PubMedCrossRef
104.
Buchanan N, Smit L, Cane RD, De Andrade M. Sympathetic overactivity in tetanus: fatality associated with propanolol. BMJ. 1978;2:254–5.PubMedCrossRef
105.
Joshi S, Agrawal B, Malla G, Karmacharya B. Complete elimination of tetanus is still elusive in developing countries: a review of adult tetanus cases from referral hospital in Eastern Nepal. Kathmandu Univ Med J (KUMJ). 2007;5:378–81.
106.
Gibson K, Bonaventure Uwineza J, Kiviri W, Parlow J. Tetanus in developing countries: a case series and review. Can J Anaesth. 2009;56:307–15.PubMedCrossRef
107.
Handel J, McCallum D. A different form of nutrition delivery. Hosp Update. 1995;21:270–7.
108.
Cook TM, Protheroe RT, Handel JM. Tetanus: a review of the literature. Br J Anaesth. 2001;87:477–87.
109.
Griggs WM, Worthley LI, Gilligan JE, Thomas PD, Myburg JA. A simple percutaneous tracheostomy technique. Surg Gynae Obs. 1990;170:543–5.
110.
Singh S, Fetters T, Gebreselassie H, Abdella A, Gebrehiwot Y, Kumbi S, et al. The estimated incidence of induced abortion in Ethiopia. Int Perspect Sex Reproduct Health. 2010;36:16–25.
111.
Gebreselassie H, Fetters T, Singh S, Abdella A, Gebrehiwot Y, Tesfaye S, et al. Caring for women with abortion complications in Ethiopia: national estimates and future implications. Int Perspect Sex Reproduct Health. 2010;36:6–15.
112.
Brabin L, Kemp J, Maxwell SM, Ikimalo J, Obunge OK, Briggs ND. Protecting adolescent girls against tetanus. BMJ. 1995;311:73–4.PubMedCrossRef
113.
Shi Z, Zeng M, Yang G, Siegel F, Cain LJ, van Kampen KR, et al. Protection against tetanus by needle-free inoculation of adenovirus-vectored nasal and epicutaneous vaccines. J Virol. 2001;75:11474–82.
114.
Elkharrat D, Espinoza P, De la Coussaye J, Potel G, Pourriat JL, Sanson-Le Pors MJ. [Inclusion of a rapid test in the current Health Ministry Guidelines with the purpose of improving anti-tetanus prophylaxis prescribed to wounded patients presenting at French Emergency Departments]. (Article in French). Med Mal Infect. 2005;35:323–8.
115.
Hashem FM, Fahmy SA, El-Sayed AM, Al-Sawahli MM. Development and evaluation of chitosan microspheres for tetanus, diphtheria and divalent vaccines: a comparative study of subcutaneous and intranasal administration in mice. Pharm Dev Technol. 2011. doi:10.​3109/​10837450.​2011.​618949
116.
Baxendale A, van Hooff P, Durrant LG, Spendlove I, Howdle SM, Woods HM, et al. Single shot tetanus vaccine manufactured by a supercritical fluid encapsulation technology. Int J Pharm. 2011;413:147–54.
117.
Merhai Z, Kumar A. Tetanus in infancy and childhood (a review of 110 cases from Addis Ababa, Ethiopia). East Afr Med J. 1986;63:736–41.PubMed
118.
George AO, Ogunbiyi AO, Amanor-Boadu S, Oluwole OA, Kumuyi O. Tetanus in Nigeria: the economic burden. Trop Doct. 2005;35:126–7.PubMedCrossRef
119.
120.
Metadaten
Titel
Tetanus in Ethiopia: Unveiling the Blight of an Entirely Vaccine-Preventable Disease
verfasst von
Yohannes Woubishet Woldeamanuel
Publikationsdatum
01.12.2012
Verlag
Current Science Inc.
Erschienen in
Current Neurology and Neuroscience Reports / Ausgabe 6/2012
Print ISSN: 1528-4042
Elektronische ISSN: 1534-6293
DOI
https://doi.org/10.1007/s11910-012-0314-3

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