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Current Neurology and Neuroscience Reports
Erschienen in: Current Neurology and Neuroscience Reports 10/2016

01.10.2016 | Neuro-Ophthalmology (A Kawasaki, Section Editor)

Visual Cortex Plasticity Following Peripheral Damage To The Visual System: fMRI Evidence

verfasst von: João Lemos, Daniela Pereira, Miguel Castelo-Branco

Erschienen in: Current Neurology and Neuroscience Reports | Ausgabe 10/2016

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Abstract

Over the last two decades, functional magnetic resonance imaging (fMRI) has become a powerful research method to investigate cortical visual plasticity. Abnormal fMRI response patterns have been occasionally detected in the visually deprived cortex of patients with bilateral retinal diseases. Controversy remains whether these observations indicate structural reorganization of the visual cortex or unmasking of previously silent cortico-cortical connections. In optic nerve diseases, there is weak evidence showing that early visual cortex seems to lack reorganization, while higher-order visual areas undergo plastic changes which may contribute to optimise visual function. There is however accumulating imaging evidence demonstrating trans-synaptic degeneration of the visual cortex in patients with disease of the anterior visual pathways. This may preclude the use of restorative treatments in these patients. Here, we review and update the body of fMRI evidence on visual cortical plasticity.
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Metadaten
Titel
Visual Cortex Plasticity Following Peripheral Damage To The Visual System: fMRI Evidence
verfasst von
João Lemos
Daniela Pereira
Miguel Castelo-Branco
Publikationsdatum
01.10.2016
Verlag
Springer US
Erschienen in
Current Neurology and Neuroscience Reports / Ausgabe 10/2016
Print ISSN: 1528-4042
Elektronische ISSN: 1534-6293
DOI
https://doi.org/10.1007/s11910-016-0691-0

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