Erschienen in:
01.06.2015 | New Imaging Techniques (A Rastinehad and S Rais-Bahrami, Section Editors)
The Role of MRI in Active Surveillance for Prostate Cancer
verfasst von:
Michele Fascelli, Arvin K. George, Thomas Frye, Baris Turkbey, Peter L. Choyke, Peter A. Pinto
Erschienen in:
Current Urology Reports
|
Ausgabe 6/2015
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Abstract
Approximately one in seven American men will be diagnosed with prostate cancer during his lifetime, and at least 50 % of newly diagnosed patients will present with low-risk disease. In the last decade, the decision-making paradigm for management has shifted due to high rates of disease detection and overtreatment, attributed to prostate-specific antigen screening, with more men deferring definitive treatment for active surveillance. The advent of multiparametric magnetic resonance imaging (MP-MRI) and MRI/ transrectal ultrasound-guided fusion-guided prostate biopsy has refined the process of diagnosis, identifying patients with clinically-significant cancer and larger disease burden who would most likely benefit from intervention. In parallel, the utilization of MP-MRI in the surveillance of low-grade, low-volume disease is on the rise, reflecting support in a growing body of literature. The aim of this review is to appraise and summarize the data evaluating the role of magnetic resonance imaging in active surveillance for prostate cancer.