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Erschienen in: Clinical Orthopaedics and Related Research® 9/2014

01.09.2014 | Clinical Research

High Early Failure Rate After Cementless Hip Replacement in the Octogenarian

verfasst von: Esa Jämsen, MD, PhD, Antti Eskelinen, MD, PhD, Mikko Peltola, MSc, Keijo Mäkelä, MD, PhD

Erschienen in: Clinical Orthopaedics and Related Research® | Ausgabe 9/2014

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Abstract

Background

Use of cementless hip replacements is increasing in many countries, but the best method for fixation for octogenarian patients remains unknown.

Questions/purposes

We studied how fixation method (cemented, cementless, hybrid) affects the survival of primary hip replacements and mortality in patients 80 years or older. Specifically, we asked if fixation method affects (1) the risk of revision; (2) the reasons for revision; and (3) the mortality after contemporary primary hip replacement in octogenarian patients.

Methods

A total of 4777 primary total hip replacements were performed in 4509 octogenarian patients with primary osteoarthritis in Finland between 1998 and 2009 and were registered in the Finnish Arthroplasty Register. Comorbidity data were collected from a nationwide quality register. Survival of hip replacements, using any revision as the end point, and mortality were analyzed using competing risks survival analysis and Cox regression analysis. The average followup was 4 years (range, 1–13 years).

Results

Cementless hip replacements were associated with a higher rate of early (within 1 year) revision compared with cemented hip replacements (hazard ratio, 2.9; 95% CI, 1.7–5.1), particularly in women. The difference was not explained by comorbidity or provider-related factors. Periprosthetic fracture was the leading mode of failure of cementless hip replacements. After 1 year, there were no differences in the survival rates although 10-year survival was slightly lower for cementless than cemented and hybrid hip replacements (93.9% [95% CI, 91.1%–96.7%] versus 97.4% [95% CI, 96.9%–98.0%] and 98.1% [95% CI, 96.9%–99.4%], respectively). Fixation method was not associated with mortality.

Conclusions

Cementless fixation was associated with an increased risk of revision and did not provide any benefit in terms of lower mortality in octogenarian patients.

Level of Evidence

Level II, therapeutic study. See the Instructions for Authors for a complete description of levels of evidence.
Literatur
1.
Zurück zum Zitat Abdulkarim A, Ellanti P, Motterlini N, Fahey T, O’Byrne JM. Cemented versus uncemented fixation in total hip replacement: a systematic review and meta-analysis of randomized controlled trials. Orthop Rev (Pavia). 2013;5:e8.PubMedCentralPubMedCrossRef Abdulkarim A, Ellanti P, Motterlini N, Fahey T, O’Byrne JM. Cemented versus uncemented fixation in total hip replacement: a systematic review and meta-analysis of randomized controlled trials. Orthop Rev (Pavia). 2013;5:e8.PubMedCentralPubMedCrossRef
2.
Zurück zum Zitat Aro HT, Alm JJ, Moritz N, Mäkinen TJ, Lankinen P. Low BMD affects initial stability and delays stem osseointegration in cementless total hip arthroplasty in women: a 2-year RSA study of 39 patients. Acta Orthop. 2012;83:107–114.PubMedCentralPubMedCrossRef Aro HT, Alm JJ, Moritz N, Mäkinen TJ, Lankinen P. Low BMD affects initial stability and delays stem osseointegration in cementless total hip arthroplasty in women: a 2-year RSA study of 39 patients. Acta Orthop. 2012;83:107–114.PubMedCentralPubMedCrossRef
4.
Zurück zum Zitat Bozic KJ, Durbhakula S, Berry DJ, Naessens JM, Rappaport K, Cisternas M, Saleh KJ, Rubash HE. Differences in patient and procedure characteristics and hospital resource use in primary and revision total joint arthroplasty: a multicenter study. J Arthroplasty. 2005;20(7 suppl 3):17–25.PubMedCrossRef Bozic KJ, Durbhakula S, Berry DJ, Naessens JM, Rappaport K, Cisternas M, Saleh KJ, Rubash HE. Differences in patient and procedure characteristics and hospital resource use in primary and revision total joint arthroplasty: a multicenter study. J Arthroplasty. 2005;20(7 suppl 3):17–25.PubMedCrossRef
5.
Zurück zum Zitat Clement ND, Biant LC, Breusch SJ. Total hip arthroplasty: to cement or not to cement the acetabular socket? A critical review of the literature. Arch Orthop Trauma Surg. 2012;132:411–427.PubMedCrossRef Clement ND, Biant LC, Breusch SJ. Total hip arthroplasty: to cement or not to cement the acetabular socket? A critical review of the literature. Arch Orthop Trauma Surg. 2012;132:411–427.PubMedCrossRef
6.
Zurück zum Zitat Corten K, Bourne RB, Charron KD, Au K, Rorabeck CH. What works best, a cemented or cementless primary total hip arthroplasty?: minimum 17-year followup of a randomized controlled trial. Clin Orthop Relat Res. 2011;469:209–217.PubMedCentralPubMedCrossRef Corten K, Bourne RB, Charron KD, Au K, Rorabeck CH. What works best, a cemented or cementless primary total hip arthroplasty?: minimum 17-year followup of a randomized controlled trial. Clin Orthop Relat Res. 2011;469:209–217.PubMedCentralPubMedCrossRef
7.
Zurück zum Zitat Davidson D, Pike J, Garbuz D, Duncan CP, Masri BA. Intraoperative periprosthetic fractures during total hip arthroplasty: evaluation and management. J Bone Joint Surg Am. 2008;90:2000–2012.PubMedCrossRef Davidson D, Pike J, Garbuz D, Duncan CP, Masri BA. Intraoperative periprosthetic fractures during total hip arthroplasty: evaluation and management. J Bone Joint Surg Am. 2008;90:2000–2012.PubMedCrossRef
8.
Zurück zum Zitat Fernandez-Fernandez R, García-Elias E, Gil-Garay E. Peroperative fractures in uncemented total hip arthroplasty: results with a single design of stem implant. Int Orthop. 2008;32:307–313.PubMedCentralPubMedCrossRef Fernandez-Fernandez R, García-Elias E, Gil-Garay E. Peroperative fractures in uncemented total hip arthroplasty: results with a single design of stem implant. Int Orthop. 2008;32:307–313.PubMedCentralPubMedCrossRef
9.
Zurück zum Zitat Flamme CH, Stukenborg-Colsman C, Wirth CJ. Evaluation of the learning curves associated with uncemented primary total hip arthroplasty depending on the experience of the surgeon. Hip Int. 2006;16:191–197.PubMed Flamme CH, Stukenborg-Colsman C, Wirth CJ. Evaluation of the learning curves associated with uncemented primary total hip arthroplasty depending on the experience of the surgeon. Hip Int. 2006;16:191–197.PubMed
10.
Zurück zum Zitat Hailer NP, Garellick G, Kärrholm J. Uncemented and cemented primary total hip arthroplasty in the Swedish Hip Arthroplasty Register. Acta Orthop. 2010;81:34–41.PubMedCentralPubMedCrossRef Hailer NP, Garellick G, Kärrholm J. Uncemented and cemented primary total hip arthroplasty in the Swedish Hip Arthroplasty Register. Acta Orthop. 2010;81:34–41.PubMedCentralPubMedCrossRef
11.
Zurück zum Zitat Havelin LI, Fenstad AM, Salomonsson R, Mehnert F, Furnes O, Overgaard S, Pedersen AB, Herberts P, Kärrholm J, Garellick G. The Nordic Arthroplasty Register Association: a unique collaboration between 3 national hip arthroplasty registries with 280,201 THRs. Acta Orthop. 2009;80:393–401.PubMedCentralPubMedCrossRef Havelin LI, Fenstad AM, Salomonsson R, Mehnert F, Furnes O, Overgaard S, Pedersen AB, Herberts P, Kärrholm J, Garellick G. The Nordic Arthroplasty Register Association: a unique collaboration between 3 national hip arthroplasty registries with 280,201 THRs. Acta Orthop. 2009;80:393–401.PubMedCentralPubMedCrossRef
12.
Zurück zum Zitat Jameson SS, Baker PN, Mason J, Rymaszewska M, Gregg PJ, Deehan DJ, Reed MR. Independent predictors of failure up to 7.5 years after 35 386 single-brand cementless total hip replacements: a retrospective cohort study using National Joint Registry data. Bone Joint J. 2013;95:747–757.PubMedCrossRef Jameson SS, Baker PN, Mason J, Rymaszewska M, Gregg PJ, Deehan DJ, Reed MR. Independent predictors of failure up to 7.5 years after 35 386 single-brand cementless total hip replacements: a retrospective cohort study using National Joint Registry data. Bone Joint J. 2013;95:747–757.PubMedCrossRef
13.
Zurück zum Zitat Jämsen E, Peltola M, Eskelinen A, Lehto MU. Comorbid diseases as predictors of survival of primary total hip and knee replacements: a nationwide register-based study of 96 754 operations on patients with primary osteoarthritis. Ann Rheum Dis. 2013;72:1975–1982.PubMedCentralPubMedCrossRef Jämsen E, Peltola M, Eskelinen A, Lehto MU. Comorbid diseases as predictors of survival of primary total hip and knee replacements: a nationwide register-based study of 96 754 operations on patients with primary osteoarthritis. Ann Rheum Dis. 2013;72:1975–1982.PubMedCentralPubMedCrossRef
14.
Zurück zum Zitat Jämsen E, Puolakka T, Eskelinen A, Jäntti P, Kalliovalkama J, Nieminen J, Valvanne J. Predictors of mortality following primary hip and knee replacement in the aged: a single-center analysis of 1,998 primary hip and knee replacements for primary osteoarthritis. Acta Orthop. 2013;84:44–53.PubMedCentralPubMedCrossRef Jämsen E, Puolakka T, Eskelinen A, Jäntti P, Kalliovalkama J, Nieminen J, Valvanne J. Predictors of mortality following primary hip and knee replacement in the aged: a single-center analysis of 1,998 primary hip and knee replacements for primary osteoarthritis. Acta Orthop. 2013;84:44–53.PubMedCentralPubMedCrossRef
15.
Zurück zum Zitat Keisu KS, Orozco F, Sharkey PF, Hozack WJ, Rothman RH, McGuigan FX. Primary cementless total hip arthroplasty in octogenarians: two to eleven-year follow-up. J Bone Joint Surg Am. 2001;83:359–363.PubMedCrossRef Keisu KS, Orozco F, Sharkey PF, Hozack WJ, Rothman RH, McGuigan FX. Primary cementless total hip arthroplasty in octogenarians: two to eleven-year follow-up. J Bone Joint Surg Am. 2001;83:359–363.PubMedCrossRef
16.
Zurück zum Zitat Kennedy JW, Johnston L, Cochrane L, Boscainos PJ. Outcomes of total hip arthroplasty in the octogenarian population. Surgeon. 2013;11:199–204.PubMedCrossRef Kennedy JW, Johnston L, Cochrane L, Boscainos PJ. Outcomes of total hip arthroplasty in the octogenarian population. Surgeon. 2013;11:199–204.PubMedCrossRef
17.
Zurück zum Zitat Mäkelä KT, Eskelinen A, Pulkkinen P, Paavolainen P, Remes V. Total hip arthroplasty for primary osteoarthritis in patients fifty-five years of age or older: an analysis of the Finnish arthroplasty registry. J Bone Joint Surg Am. 2008;90:2160–2170.PubMedCrossRef Mäkelä KT, Eskelinen A, Pulkkinen P, Paavolainen P, Remes V. Total hip arthroplasty for primary osteoarthritis in patients fifty-five years of age or older: an analysis of the Finnish arthroplasty registry. J Bone Joint Surg Am. 2008;90:2160–2170.PubMedCrossRef
18.
Zurück zum Zitat McMinn DJ, Snell KI, Daniel J, Treacy RB, Pynsent PB, Riley RD. Mortality and implant revision rates of hip arthroplasty in patients with osteoarthritis: registry based cohort study. BMJ. 2012;344:e3319.PubMedCentralPubMedCrossRef McMinn DJ, Snell KI, Daniel J, Treacy RB, Pynsent PB, Riley RD. Mortality and implant revision rates of hip arthroplasty in patients with osteoarthritis: registry based cohort study. BMJ. 2012;344:e3319.PubMedCentralPubMedCrossRef
21.
Zurück zum Zitat Ogino D, Kawaji H, Konttinen L, Lehto M, Rantanen P, Malmivaara A, Konttinen YT, Salo J. Total hip replacement in patients eighty years of age and older. J Bone Joint Surg Am. 2008;90:1884–1890.PubMedCrossRef Ogino D, Kawaji H, Konttinen L, Lehto M, Rantanen P, Malmivaara A, Konttinen YT, Salo J. Total hip replacement in patients eighty years of age and older. J Bone Joint Surg Am. 2008;90:1884–1890.PubMedCrossRef
22.
Zurück zum Zitat Parvizi J, Pour AE, Keshavarzi NR, D’Apuzzo M, Sharkey PF, Hozack WJ. Revision total hip arthroplasty in octogenarians: a case-control study. J Bone Joint Surg Am. 2007;89:2612–2618.PubMedCrossRef Parvizi J, Pour AE, Keshavarzi NR, D’Apuzzo M, Sharkey PF, Hozack WJ. Revision total hip arthroplasty in octogenarians: a case-control study. J Bone Joint Surg Am. 2007;89:2612–2618.PubMedCrossRef
23.
Zurück zum Zitat Peltola M, Juntunen M, Häkkinen U, Rosenqvist G, Seppälä TT, Sund R. A methodological approach for register-based evaluation of cost and outcomes in health care. Ann Med. 2011;43(suppl 1):S4–13.PubMedCrossRef Peltola M, Juntunen M, Häkkinen U, Rosenqvist G, Seppälä TT, Sund R. A methodological approach for register-based evaluation of cost and outcomes in health care. Ann Med. 2011;43(suppl 1):S4–13.PubMedCrossRef
24.
Zurück zum Zitat Peltola M, Malmivaara A, Paavola M. Hip prosthesis introduction and early revision risk: a nationwide population-based study covering 39,125 operations. Acta Orthop. 2013;84:25–31.PubMedCentralPubMedCrossRef Peltola M, Malmivaara A, Paavola M. Hip prosthesis introduction and early revision risk: a nationwide population-based study covering 39,125 operations. Acta Orthop. 2013;84:25–31.PubMedCentralPubMedCrossRef
25.
Zurück zum Zitat Pennington M, Grieve R, Sekhon JS, Gregg P, Black N, van der Meulen JH. Cemented, cementless, and hybrid prostheses for total hip replacement: cost effectiveness analysis. BMJ. 2013;346:f1026.PubMedCentralPubMedCrossRef Pennington M, Grieve R, Sekhon JS, Gregg P, Black N, van der Meulen JH. Cemented, cementless, and hybrid prostheses for total hip replacement: cost effectiveness analysis. BMJ. 2013;346:f1026.PubMedCentralPubMedCrossRef
26.
Zurück zum Zitat Pieringer H, Labek G, Auersperg V, Bohler N. Cementless total hip arthroplasty in patients older than 80 years of age. J Bone Joint Surg Br. 2003;85:641–645.PubMed Pieringer H, Labek G, Auersperg V, Bohler N. Cementless total hip arthroplasty in patients older than 80 years of age. J Bone Joint Surg Br. 2003;85:641–645.PubMed
27.
Zurück zum Zitat Puolakka TJ, Pajamäki KJ, Halonen PJ, Pulkkinen PO, Paavolainen P, Nevalainen JK. The Finnish Arthroplasty Register: report of the hip register. Acta Orthop Scand. 2001;72:433–441.PubMedCrossRef Puolakka TJ, Pajamäki KJ, Halonen PJ, Pulkkinen PO, Paavolainen P, Nevalainen JK. The Finnish Arthroplasty Register: report of the hip register. Acta Orthop Scand. 2001;72:433–441.PubMedCrossRef
28.
Zurück zum Zitat Ranstam J, Kärrholm J, Pulkkinen P, Mäkelä K, Espehaug B, Pedersen AB, Mehnert F, Furnes O; NARA study group. Statistical analysis of arthroplasty data: II. Guidelines. Acta Orthop. 2011;82:258–267.PubMedCentralPubMedCrossRef Ranstam J, Kärrholm J, Pulkkinen P, Mäkelä K, Espehaug B, Pedersen AB, Mehnert F, Furnes O; NARA study group. Statistical analysis of arthroplasty data: II. Guidelines. Acta Orthop. 2011;82:258–267.PubMedCentralPubMedCrossRef
29.
Zurück zum Zitat Rhyu KH, Lee SM, Chun YS, Kim KI, Cho YJ, Yoo MC. Does osteoporosis increase early subsidence of cementless double-tapered femoral stem in hip arthroplasty? J Arthroplasty. 2012;27:1305–1309.PubMedCrossRef Rhyu KH, Lee SM, Chun YS, Kim KI, Cho YJ, Yoo MC. Does osteoporosis increase early subsidence of cementless double-tapered femoral stem in hip arthroplasty? J Arthroplasty. 2012;27:1305–1309.PubMedCrossRef
30.
Zurück zum Zitat Sheth NP, Brown NM, Moric M, Berger RA, Della Valle CJ. Operative treatment of early peri-prosthetic femur fractures following primary total hip arthroplasty. J Arthroplasty. 2013;28:286–291.PubMedCrossRef Sheth NP, Brown NM, Moric M, Berger RA, Della Valle CJ. Operative treatment of early peri-prosthetic femur fractures following primary total hip arthroplasty. J Arthroplasty. 2013;28:286–291.PubMedCrossRef
31.
Zurück zum Zitat Stroh DA, Zywiel MG, Johnson AJ, Mont MA. Excellent survivorship with the use of proximally coated tapered cementless stems for total hip arthroplasty in octogenarians. Geriatr Orthop Surg Rehabil. 2011;2:100–104.PubMedCentralPubMedCrossRef Stroh DA, Zywiel MG, Johnson AJ, Mont MA. Excellent survivorship with the use of proximally coated tapered cementless stems for total hip arthroplasty in octogenarians. Geriatr Orthop Surg Rehabil. 2011;2:100–104.PubMedCentralPubMedCrossRef
34.
Zurück zum Zitat Thillemann TM, Pedersen AB, Johnsen SP, Søballe K. Inferior outcome after intraoperative femoral fracture in total hip arthroplasty: outcome in 519 patients from the Danish Hip Arthroplasty Registry. Acta Orthop. 2008;79:327–334.PubMedCrossRef Thillemann TM, Pedersen AB, Johnsen SP, Søballe K. Inferior outcome after intraoperative femoral fracture in total hip arthroplasty: outcome in 519 patients from the Danish Hip Arthroplasty Registry. Acta Orthop. 2008;79:327–334.PubMedCrossRef
35.
Zurück zum Zitat Toossi N, Adeli B, Timperley AJ, Haddad FS, Maltenfort M, Parvizi J. Acetabular components in total hip arthroplasty: is there evidence that cementless fixation is better? J Bone Joint Surg Am. 2013;95:168–174.PubMedCrossRef Toossi N, Adeli B, Timperley AJ, Haddad FS, Maltenfort M, Parvizi J. Acetabular components in total hip arthroplasty: is there evidence that cementless fixation is better? J Bone Joint Surg Am. 2013;95:168–174.PubMedCrossRef
36.
Zurück zum Zitat Troelsen A, Malchau E, Sillesen N, Malchau H. A review of current fixation use and registry outcomes in total hip arthroplasty: the uncemented paradox. Clin Orthop Relat Res. 2013;471:2052–2059.PubMedCentralPubMedCrossRef Troelsen A, Malchau E, Sillesen N, Malchau H. A review of current fixation use and registry outcomes in total hip arthroplasty: the uncemented paradox. Clin Orthop Relat Res. 2013;471:2052–2059.PubMedCentralPubMedCrossRef
37.
Zurück zum Zitat White PF, White LM, Monk T, Jakobsson J, Raeder J, Mulroy MF, Bertini L, Torri G, Solca M, Pittoni G, Bettelli G. Perioperative care for the older outpatient undergoing ambulatory surgery. Anesth Analg. 2012;114:1190–1215.PubMedCrossRef White PF, White LM, Monk T, Jakobsson J, Raeder J, Mulroy MF, Bertini L, Torri G, Solca M, Pittoni G, Bettelli G. Perioperative care for the older outpatient undergoing ambulatory surgery. Anesth Analg. 2012;114:1190–1215.PubMedCrossRef
38.
Zurück zum Zitat Wurtz LD, Feinberg JR, Capello WN, Meldrum R, Kay PJ. Elective primary total hip arthroplasty in octogenarians. J Gerontol A Biol Sci Med Sci. 2003;58:M468–M471.PubMedCrossRef Wurtz LD, Feinberg JR, Capello WN, Meldrum R, Kay PJ. Elective primary total hip arthroplasty in octogenarians. J Gerontol A Biol Sci Med Sci. 2003;58:M468–M471.PubMedCrossRef
Metadaten
Titel
High Early Failure Rate After Cementless Hip Replacement in the Octogenarian
verfasst von
Esa Jämsen, MD, PhD
Antti Eskelinen, MD, PhD
Mikko Peltola, MSc
Keijo Mäkelä, MD, PhD
Publikationsdatum
01.09.2014
Verlag
Springer US
Erschienen in
Clinical Orthopaedics and Related Research® / Ausgabe 9/2014
Print ISSN: 0009-921X
Elektronische ISSN: 1528-1132
DOI
https://doi.org/10.1007/s11999-014-3641-7

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